Basic Information

Insect: Drosophila arizonae
Gene Symbol: Cf2
Assembly: GCA_001654025.1
Location: NW:24643473-24649838[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.29 17 5.6 6.0 1 23 95 118 95 118 0.95

2 8 0.34 19 5.4 0.2 1 23 155 178 155 178 0.92

3 8 0.073 4.1 7.5 0.0 1 11 204 214 204 219 0.86

4 8 1.3e-07 7.2e-06 25.6 1.4 1 23 406 428 406 428 0.98

5 8 3.9e-08 2.2e-06 27.2 2.7 1 23 441 463 441 463 0.99

6 8 1.7e-06 9.6e-05 22.1 1.2 1 23 469 491 469 491 0.98

7 8 3.9e-07 2.2e-05 24.1 3.5 1 23 497 519 497 519 0.98

8 8 1.3e-07 7.1e-06 25.6 1.4 1 23 525 548 525 548 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.29	17	5.6	6.0	1	23	95	118	95	118	0.95
2	8	0.34	19	5.4	0.2	1	23	155	178	155	178	0.92
3	8	0.073	4.1	7.5	0.0	1	11	204	214	204	219	0.86
4	8	1.3e-07	7.2e-06	25.6	1.4	1	23	406	428	406	428	0.98
5	8	3.9e-08	2.2e-06	27.2	2.7	1	23	441	463	441	463	0.99
6	8	1.7e-06	9.6e-05	22.1	1.2	1	23	469	491	469	491	0.98
7	8	3.9e-07	2.2e-05	24.1	3.5	1	23	497	519	497	519	0.98
8	8	1.3e-07	7.1e-06	25.6	1.4	1	23	525	548	525	548	0.96

Sequence Information

Coding Sequence: ATGTTAAAGTCTAGCACAAACCCACAGGAATTGCGTCTGCCACGTCCCGAGGAACACCATCAGCCGCATCAGCACACGCAGCAGGGACAGCCGACGCATCAAGTTGCCGCCGTGATAGCCAACAATATAAcgtctgcagcagccgcagccgccgccgcagcagcagccgcagcagcagcagcaggaggaggatcAGCAGTAGTCCCCACCAGCCACAGCATGGACACGCTTAAGACAACATTTCTTCCCAATCTCAGCATGGATCCGAATGTGATTAGTCCGCACTACTGCCCCATGTGCCATCAGCAGTTCGAGCGCATCCAGCATGCGGCCGAGCATATGCAGCTCTGTCATGGCATCTCACTCAATGCCCAGAGCGCTCTCatcgaacagcagcagcagcagcatcaacaacagcagcagcaacaacaacagcagcagcagcaactgaagccGCTTAGCTATGCGTGTCCCAACTGTGATGATAAGTTTGCTAGTGCGCTGGAGGTGGATGAGCACCATCGGCTGACGCATCAGACGGCATTTTTAGCGCGCTGCATTGTGTGTAGCGTTTATGGTGTCAATTCTGTGACTCAGAATCCCAACGAATATAAATGCTCGCACTGTGGCAACGTGTTCAATGCGGCGATGTTGGCAACTGGACAGCAGGCGTTTATGGATCATCAGGAGGCACCGGTGACGCCGGATGAAATGCCAGCTATAGCGCCACGTGATATGAGACTGACGCccgaagagcagcagcaccagcagcaacaacaacagcagcagcaacaacaacagcagcagcaacaacaacagcagcaacaacaacaacagcagcaagtgcaacacCATCAGCAGGATCACCATCACCAGCAActcgaacaacagcaacagcagcaggagcaacagcgacaacgtGAACTccaggagcaacagcatcaggAGGACCTGAACGATCCGTCAACGCAGAAAGTGCCGCCCCTAACAGTGAAACTGCTAAAGAACGGCACTGGAGCAACAGTAGCACATCCGCAGGTCATCATTAAGGAGGAACCACTTAGTTTGAGCGATAGCGGCGATGTGGTCAATTCAGTGCCTGTCTATGCCATACAAGCGAATCCTGGTGTCCAGCCGGCGGGCACAACTGGCGCCGCCACCAGTGTCCTGGTCAGCACGCAATCTGTGCCCGCGGATCTGGCGCACAAGATCCGGCACAAATGTCCCGATTGCCCCAAAACATTTAAGACGCCCGGCACGCTGAACATGCACCGCAAAATACACACGGGCGAAGCAGAcgcCACGCCCAAAGAACGCCCCTACACGTGCTCCTACTGCGGCAAGTCCTTCACTCAATCGAATACACTAAAACAGCACACTCGCATACATACAGGTGAGAAACCATTTAGATGTGGCTTTTGTGGCAGGGCGTTCACTGTTAAGGATTACCTGAACAAACATTTAACGACTCACACGGGTGAAAAACCATTTCATTGTGGCTACTGTGAGAAGTCCTTCAGCGTGAAGGACTATCTCACgaaacacatacgcacacacaccggCGAAAAGCCGTACACCTGTCCGTACTGTGACAAGCGATTCACGCAACGCAGCGCACTCACCGTGCACACGACAAAGCTGCATCCGCTCTAG
Protein Sequence: MLKSSTNPQELRLPRPEEHHQPHQHTQQGQPTHQVAAVIANNITSAAAAAAAAAAAAAAAAGGGSAVVPTSHSMDTLKTTFLPNLSMDPNVISPHYCPMCHQQFERIQHAAEHMQLCHGISLNAQSALIEQQQQQHQQQQQQQQQQQQQLKPLSYACPNCDDKFASALEVDEHHRLTHQTAFLARCIVCSVYGVNSVTQNPNEYKCSHCGNVFNAAMLATGQQAFMDHQEAPVTPDEMPAIAPRDMRLTPEEQQHQQQQQQQQQQQQQQQQQQQQQQQQQQVQHHQQDHHHQQLEQQQQQQEQQRQRELQEQQHQEDLNDPSTQKVPPLTVKLLKNGTGATVAHPQVIIKEEPLSLSDSGDVVNSVPVYAIQANPGVQPAGTTGAATSVLVSTQSVPADLAHKIRHKCPDCPKTFKTPGTLNMHRKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHTRIHTGEKPFRCGFCGRAFTVKDYLNKHLTTHTGEKPFHCGYCEKSFSVKDYLTKHIRTHTGEKPYTCPYCDKRFTQRSALTVHTTKLHPL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00601993;
90% Identity: iTF_00509985;
80% Identity: -