Basic Information

Insect: Drosophila arizonae
Gene Symbol: -
Assembly: GCA_001654025.1
Location: NW:7879825-7885201[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 2.3 1.3e+02 2.8 7.8 2 23 335 357 334 357 0.96

2 17 0.0058 0.33 11.0 1.6 2 23 400 421 399 421 0.94

3 17 4.7 2.6e+02 1.8 3.0 2 17 432 447 431 458 0.75

4 17 0.021 1.2 9.2 0.3 3 23 491 511 489 511 0.95

5 17 0.0022 0.12 12.3 0.3 1 23 519 542 519 542 0.98

6 17 0.00034 0.019 14.8 0.3 2 23 547 568 546 568 0.97

7 17 0.22 12 6.0 0.0 1 20 576 595 576 597 0.93

8 17 2.5e-05 0.0014 18.4 0.5 1 22 616 637 616 640 0.90

9 17 0.015 0.86 9.6 1.1 1 21 645 665 645 666 0.94

10 17 0.015 0.84 9.7 0.2 1 23 685 710 685 710 0.96

11 17 0.0081 0.45 10.5 0.6 2 23 726 748 725 748 0.93

12 17 0.00053 0.03 14.2 0.2 2 23 754 776 753 776 0.92

13 17 0.0074 0.41 10.6 0.3 2 23 780 802 779 802 0.96

14 17 1.4e-05 0.00081 19.2 2.1 1 23 808 830 808 830 0.98

15 17 0.0083 0.46 10.5 0.6 1 23 834 857 834 857 0.93

16 17 9.9e-05 0.0056 16.5 1.0 1 23 863 886 863 886 0.97

17 17 0.00035 0.02 14.8 2.5 1 23 890 918 890 918 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	2.3	1.3e+02	2.8	7.8	2	23	335	357	334	357	0.96
2	17	0.0058	0.33	11.0	1.6	2	23	400	421	399	421	0.94
3	17	4.7	2.6e+02	1.8	3.0	2	17	432	447	431	458	0.75
4	17	0.021	1.2	9.2	0.3	3	23	491	511	489	511	0.95
5	17	0.0022	0.12	12.3	0.3	1	23	519	542	519	542	0.98
6	17	0.00034	0.019	14.8	0.3	2	23	547	568	546	568	0.97
7	17	0.22	12	6.0	0.0	1	20	576	595	576	597	0.93
8	17	2.5e-05	0.0014	18.4	0.5	1	22	616	637	616	640	0.90
9	17	0.015	0.86	9.6	1.1	1	21	645	665	645	666	0.94
10	17	0.015	0.84	9.7	0.2	1	23	685	710	685	710	0.96
11	17	0.0081	0.45	10.5	0.6	2	23	726	748	725	748	0.93
12	17	0.00053	0.03	14.2	0.2	2	23	754	776	753	776	0.92
13	17	0.0074	0.41	10.6	0.3	2	23	780	802	779	802	0.96
14	17	1.4e-05	0.00081	19.2	2.1	1	23	808	830	808	830	0.98
15	17	0.0083	0.46	10.5	0.6	1	23	834	857	834	857	0.93
16	17	9.9e-05	0.0056	16.5	1.0	1	23	863	886	863	886	0.97
17	17	0.00035	0.02	14.8	2.5	1	23	890	918	890	918	0.96

Sequence Information

Coding Sequence: ATGTCGGAAAATCCGAAACTAAACAACGAAAATGGGCCTAGCTGCCTGCATTGCAGTGTGCACAGTTCAAAGCAGAAATATCAAGAAATTTTCGATGAAGTGGGCATCGAGATAGAGCTCGCTGATCTTTTGGCAAAGTACTTCCAAATCGTTGTCAAACCCGATGCTCACAAATCGCAATTGCTGTGCCAAGAATGTGTAAATACGCTAATACGCTTCTTTGACATAGACGAGctacagcggcagcaggatgCCGCCAATGCAGCCAAAAAGGCTGCCAAGTCGCTGGATGATCTACCTAGTACTGCTAAGAAGGTAGAGAAATCCGCTAAAAAGGCGACGCCGACGTCACCAAAGACAAAGAGCGTCGCGTCTCCAGTCAAAAATTTGCCAAAGCCCGATGCAATTGCTACCACTGCCGTGGctacaactgcagcaaaaGCTTCTAATAAAGCCTTAACAGTTCTGCCCAAACGATTGCCCGATAAGGCCAAGGAGGTAGTTCCACGAAATGCCACAGCCAAGGCGAAAAATCATGGCGCGGCAGATCAGGAGCAAATCAGCGCGCTCATACGTGACATTCTGGATGATGAGGAGCCGCCGGCCGATGATAAATTTGCCgatgcagcagccacagtgcGGCAGCTAGAAAAGCAAACTGACAAAAAGCAGATACAGCAGGAGACAGTGGAAGAGCAGCTGGGACAGCTGGAGGAAGAGGATAACAATGATGAGCTGGAGTTTCTGCTAGAGCAAGATGATAACTCCTCCGATGCGGACGTGCGTCATTTCAAAGTAGAGCGTAAGGTCAAACGTACCGCTTCACAATCCTTGTCCCAATCGCAGTCACAAAATGAAAGTCAAAGCGAGGATGAATCATTTAAAGTGGAGCCTTTTAATTTTGTACTCATTAAAGAATCTGACAACATTGGCGATCTGCATGAATATCTATCGACCGTGGTCAAGACCTGCTTTGAGACTTTGCAGTTCAATTGGGCCACTGTTTGCCGTCATTGTTCGCTGAAATGCAGCAAATATGAAACTCTGCTCAGCCACATGCTGAAATGCCATCAGCTGGCCGATGAGCGCTACAGTTGTCCCATTGAAGGCTGCACGGCGGAGCTACAAGGacgcaaatatttggccatgCATCTGGTGGTGCTACACGCACCTGTGGCAGAaATACCCATCTATGGCAAGTGTCCCGAGTGTAATATGACCTTCTCcaatatattgcaatataatAAACACTCTTGCGCACACGTCATTAAAAAGCGTCGCGGCATGCGCTTATACTGTGAGATGTGTGGCCTGGAGTTTCCCTCGTGGAAGCGCTTTAATTTCCACAATCAATTTCACTTGGAGCGTCACAGGCCGCGCGCTTGTTTCGTTTGCGATTTTGCAGACAACAACATTGATGAGCTCTTCCGTCATTTGTATTATGCGCACGAGCCGGAGGGCACACTCTTTTGTGATCTCTGTGATCGCAACTTTCGTGACGCTGCCGTCTTTATGGAGCACAACAAATCGCATGCGAATGTCAGCAGCACCACCTACAGCTGCTCGGAGTGCAGCGCCAACTTTGAGACACGCGGTCGTCTCAACGGTCATCTGCGCTCCGTTCATGGCAGCGTCATCAGCTGCGAGTTGTGCAGCCGCGAGTTTGCCACAGAGGCGACCTACAATCTGCATATGAAGACACATTTGATCATCGAGCGTCAGGTGCACGTGTGCAGCGGCTGTGGACTGCTCAGCGATAGTAAAGCGAAGCTGCAGGCTCATGTGGAGGCGGAGGACTCGGCCTGCTTTGGCTTGGAGACCTATGCGGAACTTTTACGCAATGCTTACGTCTGTGAATATTGCTCGGAATACTTCAAGCAGAAGAGCGATTTGCGTGCCCATCGCGACTCGGGCGTGCATAAGGACGGATTCTTCATATGCCATCCGTGTGACAAGGCCTTTGCCGACATGAAACTCTATCGTCATCATTTGCGCAActttcagcagcagcgctcAGATGTATCGCATCGCAAGCTAGAGATATGTCTCTACTATATGTGCGATTATGAGGATTGCGCTGAGGCCTACATTAACTGGAACTCGctgtacacacacaagcgACGTTCGCACGATGCCATTGCGAGAAATGAGCCGCTGATCAAGGAAAACGAATGGATCTGCCAGTTCTGCCAGAAGCAATATCGTTCCAAAATGTCGCTATCGGTGCATGTGGCGCGTAGTCATAATAATAATAATGTTGTATGCCCCCTATGCAAGGCCTCCTATAAGGATAACGATGCCCTGACTAAACATCACGCCTATTGGCATGAGCCCATGGAATGCAGTTTGTGCTTGAAAGTGGTTAAAAATCGTCGCAATTACGATACACACATGAATGTGGTGCATTCGAATAACAAACGCTACTCGTGCAGCGTCTGCCAGAAGGGCTTCTATCATAAAAGCGAAATGGAGGCGCATCAGCGGCTGCATAACCAATCGTATAGCTGCGACCAGTGCAGCTTCGTCACGCGGAACAAGAAGTCGCTGTCGGTGCATGTGCTGGGCCAGCACTTCAAGCGGTTCGCCTTCGAGTGCAAGGCGTGCAACAAGCGGTTCGGACGTCGCCAGGGCCTCTCGAATCACATGCAGCGTGTGCATGGTTCACGCTATACGTGTCACGACTTCTTCGATAGTGGATGCAGCAAATCTTTCAGCTCGACGacgcaattgaaattgcatgTGCGTAAAGCGCACAATGGCAGCATTTACGTAGAAGATGACACTGTGAAAGGCGATGAACTAGATGATctggaggagcaggagcaggagcaggaacaaGAGCAGGAAcaagaggaggagcaggagcaggatcAGCAGGATGAGCAGAAGGAAGTAAACAGCGACGGTCCGTCCTCATCGAAGAAACGCTGCATACGCATCAACGCGAATACGCAAATCGAGTTTATTGGAAACTCATTGGAGAATAAGGAAACGGAGATGTTTGAGGAGCTGCACGAGCCCAAGCCGAAtaagaggcagaggcaaaaaTAA
Protein Sequence: MSENPKLNNENGPSCLHCSVHSSKQKYQEIFDEVGIEIELADLLAKYFQIVVKPDAHKSQLLCQECVNTLIRFFDIDELQRQQDAANAAKKAAKSLDDLPSTAKKVEKSAKKATPTSPKTKSVASPVKNLPKPDAIATTAVATTAAKASNKALTVLPKRLPDKAKEVVPRNATAKAKNHGAADQEQISALIRDILDDEEPPADDKFADAAATVRQLEKQTDKKQIQQETVEEQLGQLEEEDNNDELEFLLEQDDNSSDADVRHFKVERKVKRTASQSLSQSQSQNESQSEDESFKVEPFNFVLIKESDNIGDLHEYLSTVVKTCFETLQFNWATVCRHCSLKCSKYETLLSHMLKCHQLADERYSCPIEGCTAELQGRKYLAMHLVVLHAPVAEIPIYGKCPECNMTFSNILQYNKHSCAHVIKKRRGMRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCDFADNNIDELFRHLYYAHEPEGTLFCDLCDRNFRDAAVFMEHNKSHANVSSTTYSCSECSANFETRGRLNGHLRSVHGSVISCELCSREFATEATYNLHMKTHLIIERQVHVCSGCGLLSDSKAKLQAHVEAEDSACFGLETYAELLRNAYVCEYCSEYFKQKSDLRAHRDSGVHKDGFFICHPCDKAFADMKLYRHHLRNFQQQRSDVSHRKLEICLYYMCDYEDCAEAYINWNSLYTHKRRSHDAIARNEPLIKENEWICQFCQKQYRSKMSLSVHVARSHNNNNVVCPLCKASYKDNDALTKHHAYWHEPMECSLCLKVVKNRRNYDTHMNVVHSNNKRYSCSVCQKGFYHKSEMEAHQRLHNQSYSCDQCSFVTRNKKSLSVHVLGQHFKRFAFECKACNKRFGRRQGLSNHMQRVHGSRYTCHDFFDSGCSKSFSSTTQLKLHVRKAHNGSIYVEDDTVKGDELDDLEEQEQEQEQEQEQEEEQEQDQQDEQKEVNSDGPSSSKKRCIRINANTQIEFIGNSLENKETEMFEELHEPKPNKRQRQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00551740;
90% Identity: iTF_00549700;
80% Identity: -