Basic Information

Insect: Drosophila arizonae
Gene Symbol: -
Assembly: GCA_001654025.1
Location: NW:2272935-2275803[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.6e-06 9.1e-05 22.2 1.4 1 23 101 123 101 123 0.98

2 14 0.0048 0.27 11.2 6.2 1 23 129 151 129 151 0.96

3 14 1.8e-05 0.001 18.8 0.9 1 23 157 179 157 179 0.98

4 14 3.8 2.2e+02 2.1 1.5 2 13 186 197 186 199 0.87

5 14 0.00014 0.0081 16.0 0.0 2 23 203 224 202 224 0.97

6 14 2.8e-07 1.6e-05 24.5 1.8 1 23 230 252 230 252 0.98

7 14 0.0022 0.12 12.3 2.3 1 19 258 276 258 278 0.96

8 14 0.004 0.22 11.5 0.5 1 21 418 438 418 439 0.93

9 14 0.00011 0.0063 16.4 2.9 1 23 453 475 453 475 0.98

10 14 0.042 2.4 8.3 4.8 1 23 494 516 494 516 0.98

11 14 0.00019 0.01 15.7 2.9 1 23 524 546 524 546 0.98

12 14 0.00042 0.023 14.6 7.1 1 23 552 574 552 574 0.99

13 14 0.023 1.3 9.1 7.0 1 23 580 602 580 602 0.96

14 14 0.0023 0.13 12.2 3.9 1 23 608 630 608 630 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.6e-06	9.1e-05	22.2	1.4	1	23	101	123	101	123	0.98
2	14	0.0048	0.27	11.2	6.2	1	23	129	151	129	151	0.96
3	14	1.8e-05	0.001	18.8	0.9	1	23	157	179	157	179	0.98
4	14	3.8	2.2e+02	2.1	1.5	2	13	186	197	186	199	0.87
5	14	0.00014	0.0081	16.0	0.0	2	23	203	224	202	224	0.97
6	14	2.8e-07	1.6e-05	24.5	1.8	1	23	230	252	230	252	0.98
7	14	0.0022	0.12	12.3	2.3	1	19	258	276	258	278	0.96
8	14	0.004	0.22	11.5	0.5	1	21	418	438	418	439	0.93
9	14	0.00011	0.0063	16.4	2.9	1	23	453	475	453	475	0.98
10	14	0.042	2.4	8.3	4.8	1	23	494	516	494	516	0.98
11	14	0.00019	0.01	15.7	2.9	1	23	524	546	524	546	0.98
12	14	0.00042	0.023	14.6	7.1	1	23	552	574	552	574	0.99
13	14	0.023	1.3	9.1	7.0	1	23	580	602	580	602	0.96
14	14	0.0023	0.13	12.2	3.9	1	23	608	630	608	630	0.99

Sequence Information

Coding Sequence: ATGCGAATCATGAGTGGTATAATCGACCTGTCCTGTGTGAAAATTGAGCGAGaccaggagctggagcagcagcaggaattcTGTGGAATCTTGGAGAACGCCAACAGTGCTCAACTAAAAACTGAATTGCCTTTCGCAGAGATGGACATAGGACCTGTTAAAGTAGATCCGGATGGATTGAAAGAGGAGCCAGCAGGCAAGGGGCAGATTAAACAAAGAAATGAGTCTCCGAGGACtcgcaagaagaagagagctGCTGCACCAGCAGTTGCTGTTCCTCCTACTGATGCCAAGAGACACTATCAATGCCCACATTGTCCACGGCATTTCGAACGCAGCGATGAGCTGAGTATCCACCtgctaatacacacacataatctATCCTACAAGTGTTCCTACTGCCCGTGCAGCTTTTCGCACAAATCCATCTATACAAGCCACATGTATGGACATACGGGGAAATTTCCACATCAGTGCCCCGACTGTCCTCAgggatatatgaaatatgcggATCTGATGAAGCACCAACGCACGCACATTATCAAGGATTTGAACCGGTGTCCTTTGTGTCCCAAGAATTGCATACATAAAGGCAAGAGTTTTCTCCAATGCCCGGAATGTCCACGCGTCTTTGCCAAAGGCTTCGAATTGGAAATCCATCTGCAGATCCACAGCAACAAGTTGCCCTACAAGTGCCCACATTGTCCAATCAGTTTTGCCCACAAATCGAATTTTATAGCGCACGTTCGCGAGCATACGGGCCAGTTTCCTCATAAATGCCCGAATTGTCCGAAAGGATTTATGAAGCGCACTGATTTGATTAAGCACAATTGCGAAGGGTGGAATACTCCAAGCAGGGcgaacaaaaggaaaaaaagtgGCATTGATAAGGAGGGTGTGGAGCCAGTGGAGCAACATAAGGCGCTGCTAAAAAAGGAGCCAGTTAAGAGTCAGGTGGAAAGAAGGAGCAGTCCAAGAGTCAAAAGGCCTGAAAAGGAATCGACAACAGCAGGGAGCATACAAGAACCGAGGAAGGAgatgcagctggagcagcaggcaTCCATAAAAAAAGACAGTGCCTTAGCGAACCTGAACAGTAAAAATGATTCAAAGCTGACCTCTATCAAAACAGAGCCGcaggaggaagaggagcagAGCACGCCTAAGCAGCAGCCTTTAAATGTTAACTCAAGACTCAAAGCCAGAAAACCTATGGAGCAGCCCGTTGTAAGAATTAAGAGGCTGCGCAGCCATacatgcaatttatgcagcaaGGAATTCCCAACAGTCCAGGAACTGCAAATGCATGAAAAACGCTGCGCCTCGTCGAGCAGGCCAGGCGAGGAATCAAGTCCTTATAAATGTGAGCATTGCTTGAGGAAGTTCGCCCAGTTGTCCAGCCTCACAGAGCACAAACTCAGTCATGTGGCAACACTTCCAGATAAATCCCCGCCTCCTGTGCGTCCAGTCAAGAAGCCATTTAAGTGTCCGCACTGTGCGTGCACCTTTGACAGCACTTTGAATCGGAAAAACCATTTGCAAATCCATCAGGCCCAGAGCAATTATTCCTACAAGTGTCTGCATTGTGCAAGGACCTATCAGCAGAAGTCGAACTTTCTGGCGCACTTGCGCGGACACACGGACGAGCGTCCCTATCAGTGCTCCTACTGCATGAAGGTCTTCAAACACAGCCACGTTCTGAAGAAACATCTGCGCAATCATAGGGGCGATCGGCCGTACCTATGTCTGCATTGCCTGCAAACCTTTGCGCAGAGCTCGCACTTCCATGAGCATCTACAAAAACATGCCAACGAAATGCCATACAAGTGTCCACATTGCACGCGGTTCTTCCTTAAGGCCGTTAGCTACAAACTACATCTGCGCACCCATACGGGCGGAAAATCGTGA
Protein Sequence: MRIMSGIIDLSCVKIERDQELEQQQEFCGILENANSAQLKTELPFAEMDIGPVKVDPDGLKEEPAGKGQIKQRNESPRTRKKKRAAAPAVAVPPTDAKRHYQCPHCPRHFERSDELSIHLLIHTHNLSYKCSYCPCSFSHKSIYTSHMYGHTGKFPHQCPDCPQGYMKYADLMKHQRTHIIKDLNRCPLCPKNCIHKGKSFLQCPECPRVFAKGFELEIHLQIHSNKLPYKCPHCPISFAHKSNFIAHVREHTGQFPHKCPNCPKGFMKRTDLIKHNCEGWNTPSRANKRKKSGIDKEGVEPVEQHKALLKKEPVKSQVERRSSPRVKRPEKESTTAGSIQEPRKEMQLEQQASIKKDSALANLNSKNDSKLTSIKTEPQEEEEQSTPKQQPLNVNSRLKARKPMEQPVVRIKRLRSHTCNLCSKEFPTVQELQMHEKRCASSSRPGEESSPYKCEHCLRKFAQLSSLTEHKLSHVATLPDKSPPPVRPVKKPFKCPHCACTFDSTLNRKNHLQIHQAQSNYSYKCLHCARTYQQKSNFLAHLRGHTDERPYQCSYCMKVFKHSHVLKKHLRNHRGDRPYLCLHCLQTFAQSSHFHEHLQKHANEMPYKCPHCTRFFLKAVSYKLHLRTHTGGKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00551734;
90% Identity: iTF_00549697;
80% Identity: -