Basic Information

Insect: Drosophila arizonae
Gene Symbol: kipf
Assembly: GCA_001654025.1
Location: NW:13371975-13373208[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 3.6e-08 2e-06 27.4 0.2 2 23 153 174 152 174 0.97

2 8 5.1e-06 0.00029 20.6 4.0 1 23 180 202 180 202 0.97

3 8 5e-08 2.8e-06 26.9 1.4 1 23 208 230 208 230 0.99

4 8 1.8e-07 9.8e-06 25.2 0.8 1 23 247 269 247 269 0.98

5 8 1.9e-07 1e-05 25.1 0.5 1 23 275 297 275 297 0.98

6 8 5e-07 2.8e-05 23.8 2.7 1 23 303 325 303 325 0.99

7 8 2e-07 1.1e-05 25.0 4.7 1 23 331 353 331 353 0.99

8 8 3.7e-06 0.00021 21.0 2.3 1 23 359 381 359 381 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	3.6e-08	2e-06	27.4	0.2	2	23	153	174	152	174	0.97
2	8	5.1e-06	0.00029	20.6	4.0	1	23	180	202	180	202	0.97
3	8	5e-08	2.8e-06	26.9	1.4	1	23	208	230	208	230	0.99
4	8	1.8e-07	9.8e-06	25.2	0.8	1	23	247	269	247	269	0.98
5	8	1.9e-07	1e-05	25.1	0.5	1	23	275	297	275	297	0.98
6	8	5e-07	2.8e-05	23.8	2.7	1	23	303	325	303	325	0.99
7	8	2e-07	1.1e-05	25.0	4.7	1	23	331	353	331	353	0.99
8	8	3.7e-06	0.00021	21.0	2.3	1	23	359	381	359	381	0.98

Sequence Information

Coding Sequence: ATGGATGAAGTTTGTCGCGTTTGCACAAGCAGCGCAGTCACTCTAGTGGATATATTCGCCAAGCGCGACCAATCCGACGAATCCGAGCCCTGTCTGGCCGAGATGCTGAACGAATGCGTTGACTGTCTCGTAAGACGCGACGATCCGTTTCCCAAACAAATTTGCTTATCCTGTGTGCTGGCTGCGCAAAATGCATATCGTTTCAAACGGAGGTGCGAGCAGAGCTATCAACACTTCTGTCAGCTGCTCCGCGAGGCGTGGCAATATCCGGAGTGCACCATCAAAGTAGAAGCTAAGGAAATTGAGGAAGAGGAGCGAGGAGTCAATAGAAACAATATAGAAGTGCACATAAAGAGCGAGGAGCAGGAGTTCATGGAACCGATAGCCAACTCAAACACCAGTGAACAGCTCAATGAATCAGTCCAACTGCAATCAAGTAAATCGGACAATGCTCAGCCATGTCCCGTTTGCTCAAAGGCTTTCACGAACCAAGGCAGCCTTAAGAGGCATATTCGGATTCATTCCGGCGAGCGACCCTATACCTGCATCTACTGCCAAAAGACCTTCAATCAAAGTGGTAACCTGCACAAACATATGAGATTGCACACAGGCGAGCGCCCGTTTAAGTGTGTCGAGTGCCCGAAGTCCTTCACACAGAGCAATCATCTGGCCAATCACATACGCATTCACATACGTTCATGGCAGGTTAAGGAGCGGCCTAGTCCTGTCGACAGACTATACAAGTGCACAGAATGCTCAAAGGCCTTCACTAGCAAATGGTATCTGCAGGAACACATACGCGCCCATGCCGGTGAACGTTCCTTCAAGTGTAGCCTTTGCCCCAAGACATTTCCGAGTAGCGCAGATCTGCAGCGGCACAGTCGGGTTCACTCTGGCGAAAGGCCGTATAAGTGCATGCACTGTCCAAAAACGTTTACCCAAATTGTTAATCTGGAAAGGCATAAACGTGTCCATTCTGGGGACCGCCCCTATCAGTGTCCACATTGTCACATGGCCTTCACGCAGAGCAGCCATTTGGTCAACCACATTCTCACTCATTCGGGAGAACGGCCTTTTCAGTGCTTGGAGTGCATGAAGAGCTTCACCCGGAAAGAGTATCTAGAAAAACATAGACGAATTCACTCATTTCCATAA
Protein Sequence: MDEVCRVCTSSAVTLVDIFAKRDQSDESEPCLAEMLNECVDCLVRRDDPFPKQICLSCVLAAQNAYRFKRRCEQSYQHFCQLLREAWQYPECTIKVEAKEIEEEERGVNRNNIEVHIKSEEQEFMEPIANSNTSEQLNESVQLQSSKSDNAQPCPVCSKAFTNQGSLKRHIRIHSGERPYTCIYCQKTFNQSGNLHKHMRLHTGERPFKCVECPKSFTQSNHLANHIRIHIRSWQVKERPSPVDRLYKCTECSKAFTSKWYLQEHIRAHAGERSFKCSLCPKTFPSSADLQRHSRVHSGERPYKCMHCPKTFTQIVNLERHKRVHSGDRPYQCPHCHMAFTQSSHLVNHILTHSGERPFQCLECMKSFTRKEYLEKHRRIHSFP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00554514;
90% Identity: iTF_00549683;
80% Identity: -