Basic Information

Insect: Drosophila arawakana
Gene Symbol: prg
Assembly: GCA_018151165.1
Location: JAECWX010000394.1:2037551-2039368[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 1.5 85 3.7 0.7 1 19 228 246 228 251 0.73

2 9 0.0016 0.094 13.1 2.3 1 23 257 279 257 280 0.95

3 9 9.9e-07 5.7e-05 23.2 1.4 1 23 286 308 286 308 0.98

4 9 1.1e-07 6.4e-06 26.2 4.3 1 23 314 336 314 336 0.98

5 9 2.2e-05 0.0013 18.9 0.9 1 23 342 364 342 364 0.98

6 9 0.0039 0.23 11.9 0.6 1 23 370 392 370 392 0.98

7 9 3e-06 0.00017 21.7 1.0 1 23 446 468 446 468 0.97

8 9 5.8e-05 0.0033 17.6 0.2 3 23 475 496 473 496 0.91

9 9 0.11 6.2 7.3 1.6 1 23 500 522 500 522 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	1.5	85	3.7	0.7	1	19	228	246	228	251	0.73
2	9	0.0016	0.094	13.1	2.3	1	23	257	279	257	280	0.95
3	9	9.9e-07	5.7e-05	23.2	1.4	1	23	286	308	286	308	0.98
4	9	1.1e-07	6.4e-06	26.2	4.3	1	23	314	336	314	336	0.98
5	9	2.2e-05	0.0013	18.9	0.9	1	23	342	364	342	364	0.98
6	9	0.0039	0.23	11.9	0.6	1	23	370	392	370	392	0.98
7	9	3e-06	0.00017	21.7	1.0	1	23	446	468	446	468	0.97
8	9	5.8e-05	0.0033	17.6	0.2	3	23	475	496	473	496	0.91
9	9	0.11	6.2	7.3	1.6	1	23	500	522	500	522	0.98

Sequence Information

Coding Sequence: ATGTTAATATTAGGCACAGAAGAAGCGACACTTTCAAATGACGATAAAAACAATAACCCAGTGCCCGCGATGGAATCAATACACTGTCGTTTATGCCACTCGCGAACATATTTGGATCCAGAAGCACCCAATATTTACGAGTCGACTGTAGATTTTTGCCGGGACGGTTGCGAAAATAATGAAAATGAAAAGCACTTAATAGTTGATGTATGCCAAGGACTTTGGGGTCTCAAATACGAGCGACATGAATTCCTGCCCGAGCGCATCTGTGCGAATTGTGTTGAAATGCTAAGGGATTTCTACGCGCAACGAAAAGGCATGATACAACGAGAGTCTGAGTTGCAACAGGAATTAAAGAATATGGTCACTTTGGACGCCAAATACCGACCAGGATTAAATGGAAATCCCGGCGTCTTTGAATTCGGCGAGGGTGAAGAAGGCTGCGTGATTGTAGACATCGATCCAGATCAATTGTGTGAGACAAGCGATGATGAGTTCTTGGGCACCGACGGCGAGGCTGACGTCGAGGATGATGAGTGGGATGAAGAGGACGAGGAGGAAACGCAAAATGATGATGACGCAGAGATGCCGCTCGGCATGGATGCAGCACAAATGGCACTAATGCAAGCGCACCAAACGGTTGACATGATGACCAATGCCAGTGCTCATCCGAAGAGCGCATTCCTCTGTCAATATTGCGATTTGGCCTTTACCCTGGAACCAGATTGCCAGCAACATGAGGCCTCATCTCACGATCCTATGGCTCCATACTGCTGCAACTACTGTCAACTGCGGCTGACCACGCGTCCCGCCCTAATAGCACATATCAAGGAACACCATGACGCAGATCGTCCTTATGTGTGTGCCCATTGCAACAAGGGATTTGTTCGTCGTTCGGATCTGAAAAAGCACACAATAGTACATACTGGTGTAAGACCCTTCTCTTGCCACGTTTGCTCCAAGAGTTTCTCGCGCAACACGAATCTTACCAAGCATTTACGAATCCACAGCAGTATAAAGCCATTTGTGTGCCAAAAGTGTCCACGTTCCTTTCAAACGGCTTTGGAGCTAATGAAGCACACCCGATCCCATGCAGAAATTAAACAATTCCAATGCGATCGCTGTATCGCCTCCTTTGCACGCCGGGATAAACTCCTGATGCACCAACAGATGCACATCAGACGTGATGCGGAGCAGCAGCAGCAGAGCGCTAGGATAAACATGAGCTTGACACCGGAGCAAGTGCAGCTGCCGCTCCATCCATATGTAGAAGCCGATGGAGCTGCCTATCAGCAGCAGGTGACGCCCTCAGCCAAGGTGAGAACTGGGCGCGGCTATCGTTGCACCGTCTGTGATAGAAGTTTCCAGCGGGAACGAGATCTGCAACGTCACCAGGCTCTGCACATGGACACACTGTTGGCCTGCAAGCTATGTGGCCAGGGATTTAACCGACGCGAGCAGTTGCAACGTCACGAGCTGGAGGCACATGGTCCTAGCTACACTTGTGCCATTTGTTGCATCACCTTCTTGCAGCAGTCTGAGCTGGAAACTCATTTCAAGGTCCATGAACTGCAGCACAATGTGGCCAAGTGTGCCCAGGAAGCATTGAATGCTGCAGTTCAGCCCTTGCCACTTCCGGCGGGCACTGAGCAAGCTAGAGTGGCTGTGCCACCTGCTGCTCAAGAGCTTCCAGTTCCGGTTCCATTGCCCAACGTAAGACCCACAGCAGCAGAGATGTCCTTCTACAGCAACATGATACCCACCATGAATCTGGGTTTCTACAGCGAGACGCGTCCGGAGGAACGCAACGGAATATGA
Protein Sequence: MLILGTEEATLSNDDKNNNPVPAMESIHCRLCHSRTYLDPEAPNIYESTVDFCRDGCENNENEKHLIVDVCQGLWGLKYERHEFLPERICANCVEMLRDFYAQRKGMIQRESELQQELKNMVTLDAKYRPGLNGNPGVFEFGEGEEGCVIVDIDPDQLCETSDDEFLGTDGEADVEDDEWDEEDEEETQNDDDAEMPLGMDAAQMALMQAHQTVDMMTNASAHPKSAFLCQYCDLAFTLEPDCQQHEASSHDPMAPYCCNYCQLRLTTRPALIAHIKEHHDADRPYVCAHCNKGFVRRSDLKKHTIVHTGVRPFSCHVCSKSFSRNTNLTKHLRIHSSIKPFVCQKCPRSFQTALELMKHTRSHAEIKQFQCDRCIASFARRDKLLMHQQMHIRRDAEQQQQSARINMSLTPEQVQLPLHPYVEADGAAYQQQVTPSAKVRTGRGYRCTVCDRSFQRERDLQRHQALHMDTLLACKLCGQGFNRREQLQRHELEAHGPSYTCAICCITFLQQSELETHFKVHELQHNVAKCAQEALNAAVQPLPLPAGTEQARVAVPPAAQELPVPVPLPNVRPTAAEMSFYSNMIPTMNLGFYSETRPEERNGI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00537663;
90% Identity: iTF_00471035; iTF_00569142;
80% Identity: -