Basic Information

Insect: Drosophila arawakana
Gene Symbol: zfh1
Assembly: GCA_018151165.1
Location: JAECWX010000001.1:7554010-7558342[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3e-05 0.0017 18.5 1.0 1 23 149 171 149 171 0.97

2 15 0.00092 0.053 13.8 1.2 3 23 179 199 177 199 0.94

3 15 0.0001 0.0058 16.9 0.1 1 23 352 374 352 374 0.98

4 15 0.00094 0.054 13.8 2.2 1 23 380 402 380 402 0.98

5 15 3.5e-05 0.002 18.3 3.2 1 23 433 456 433 456 0.96

6 15 0.00067 0.038 14.3 1.9 1 23 496 518 496 518 0.95

7 15 0.077 4.4 7.8 1.8 1 23 524 547 524 547 0.97

8 15 0.029 1.7 9.1 0.4 3 19 556 572 555 573 0.95

9 15 0.00017 0.01 16.1 5.6 1 23 582 604 582 604 0.97

10 15 0.045 2.6 8.5 1.2 2 23 610 631 609 631 0.96

11 15 1e-05 0.00059 20.0 1.0 1 23 640 662 640 662 0.98

12 15 0.0012 0.067 13.5 0.1 3 23 670 690 668 690 0.97

13 15 6.2e-05 0.0036 17.5 0.5 1 23 696 718 696 719 0.95

14 15 0.18 10 6.6 0.3 1 23 729 751 729 751 0.96

15 15 0.0033 0.19 12.1 0.1 1 23 1295 1317 1295 1317 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3e-05	0.0017	18.5	1.0	1	23	149	171	149	171	0.97
2	15	0.00092	0.053	13.8	1.2	3	23	179	199	177	199	0.94
3	15	0.0001	0.0058	16.9	0.1	1	23	352	374	352	374	0.98
4	15	0.00094	0.054	13.8	2.2	1	23	380	402	380	402	0.98
5	15	3.5e-05	0.002	18.3	3.2	1	23	433	456	433	456	0.96
6	15	0.00067	0.038	14.3	1.9	1	23	496	518	496	518	0.95
7	15	0.077	4.4	7.8	1.8	1	23	524	547	524	547	0.97
8	15	0.029	1.7	9.1	0.4	3	19	556	572	555	573	0.95
9	15	0.00017	0.01	16.1	5.6	1	23	582	604	582	604	0.97
10	15	0.045	2.6	8.5	1.2	2	23	610	631	609	631	0.96
11	15	1e-05	0.00059	20.0	1.0	1	23	640	662	640	662	0.98
12	15	0.0012	0.067	13.5	0.1	3	23	670	690	668	690	0.97
13	15	6.2e-05	0.0036	17.5	0.5	1	23	696	718	696	719	0.95
14	15	0.18	10	6.6	0.3	1	23	729	751	729	751	0.96
15	15	0.0033	0.19	12.1	0.1	1	23	1295	1317	1295	1317	0.97

Sequence Information

Coding Sequence: ATGAACAATCAGGATTATGGCGGCATCCAATGGATACAGCAGCACGCATCTGCAGTCGACTCCGAAACGGATATGCTGGAAAGCGGCGCTGGCGACAGCGAGGTGACTGCAGCTTATTTGGTGAACGGCAATGCCACCGACGAGGATCTTGATCATATGGCGGCCGAGAATCTTATATTCATGGCACGAGATGGTCAGCTAAGCGAAATAATAGCTGCCAATGAATCGGGTGGAGGCACAGTGCTCATCACCGACGGTGGCGTCGCTTATGCCGAGTCATTCGACGATGACGCCCAAGTGGTCACCGAGGAGATCATCACGGATGATTGGGTGCAGCATCAAGGCGCCGAGCGTGTGGAAATCGCCGCTGAGCAAATTGCTGGCAATGCAAATGCGCTGGAGCTACTGGATATGGAGCAGGACGAGTATACGGCACTGCGTCCCTATCCCTGTGATTTCTGTAGCCGTCGTTTTCGCAAAAAGGCCAGTCTCAACAATCATATGCTGGCCCATCAGAACGATCGTCCTCATCTCTGTAAACTCTGTGGAGCACGTTTCTCCCGTCGCGCCGAACTCATCAGCCACTTTAAGGCACATGCCGAGGCACAGGATGCAGCGGATGCCGAGGCTGCAGCGGCAGCATCGATTAAATTTGAACCACCACAGATACAGCGACAAGTGGACGATCATTTCTATGACCAGGAGTGGCCACTGTACCAAGAACAGGAGCAACTTCAGGATCAAACCCAGCAAGTGGAACAGGAACAACTTACCGTGGCCAGTCAGGTAGTGCAAGAGGCTAGCTATGCGGCAGTTAGCAATGTGCCCGCTCCAACAGCCGCTCGTGGTCGCATTAGTCGTCTCAAGCCCAAGGAGGAGAGCACCCAGTACATTGTGATTGCGGAGAAACAGACGCCGGATGAGCTGCCCCAGTTTGTGGACTGCGAGGAGCCGCTAACGGTGACTGCCACATCCAGTGATGCCAACAATCCCACGGACAATGGCCAGGCCATGGACGCGTCTCGTTTCCCAGTGTTAGACGACAGCAAACCCTTCGTGTGCCAGCAATGCGGCTTAGCATTTGCCCGCGAGAAGGCGCTGGTGTCACATATCAAGAATCATCGCGTGGACTCGCCGTTTGAGTGTAATCAGTGCCAGGAGATGTTCTGGGACAATCACAGTCTGCAGGAGCATCAGAAGACGCATCAGTTCGAAGAGAGCAATTCCGAGTATGATCCCGCTTCGGCGGGTGAGGACAGCGCCAGTGAATCGGAGCCAGATCAGCTTTATGGTGAATTTTACTGCAGCGAATGTGGCATATCTTTTCACAGGCAGGACCTGCTCCGACGTCACACCAAGCAGCAGCATAAGCTGTCCATGGCCACCACCATGAGTTCCAATCCGGATGCGGAGGGCAGTGCAGATGCCGATGTTGATGGCGTTACGGACGTCGATGGCGATGGTGAGAATACCAAAGATACGACACATTGTTGTCATACCTGTGGCAAGTCTTTCCCCAGCGCCTTGGAGCTACTTGCTCATGCCGAGATTCATGCACGTCTCCCGCCCTTCAAATGTGTTCTATGTGGCAGCAGCTTCTACGAGGAGCAGGCCATCAAGCGGCATCTACACACACGGCATCCCCACGAGCTGAAGCCCAACTCGTGTGTGCTCTGTGGCAAGGAGTGTCGGGATCGCAAGGCCTTGATTAAACACGCCTGGGATCACTCTCGCGAAAAGTGCCACTCGTGCTCCAAGTGCGGCAAGAATTTCCACAACAAAGCGCGTCTGAAGCGGCACATGGCCTCGCACCGGGACAAGTCGGTGGTGTGCGAGGTCTGCCACGAGGAGTTCCCCGACGGACGCACACTGTCCAATCATCGGCATTCGCATAGCACCACATCTCCGGGCAAACTGTTTCCCTGCCACGAGTGCGGAAAGACCTTTGGCTCACGCAGCTCCCAGCAGATCCATGTACGCATACATACGGGTGAGCGACCCTACGGTTGTCGCTACTGCTGGAAGGCCTTTGCTGACGGCGGCACACTGCGCAAGCACGAGAGGATTCACACTGGCGAGAAGCCCTATGCCTGCTCCGTCTGTCCACGGGCATTCAACCAGCGTGTGGTTCTTAGGGAGCACATTCGATCCCATCACTCGGGATTGGATTCAGTGCGTGGCACATATCATTGCACCGTCTGTGCAGCCGATCTGACCACATCCAATGAGCTCATCCAGCATCTCATTCAACACAGCGACACGAACACAGCCAAACAACGACAGCCAATCACTGGTCCACGCAAGTACAAGCGTCGCAGAAAACTCCAGCCACATGAGATTGCTCATCTGCGGGCGGAGAACAAGGATGAAGAGGATTATGGCAGCGATATGGATCTCTGTGATCTGGATATGGAAAATGTCGACGATCTCTTTGAGGCGGCGGAAGCAGTGCCAGCCAAGAAGGAGAAACGCAAACGCACGGCAGGAGGTCAAGCCAAGGCGACTCCAGGACCCACAAATGGCATCTCCACATCCGCTCTGAACAACAACAACAATAACAACAACACAAGTAAACCAGCCAATGGGAATCAGGATCGCCTGTGGGAGGAAAAGTTCCTGCAGGCTAATGGCAGTGGCGGTGGCACTGTGCCCGCCTCCAATTCCTTGTCAGAGAATTTCTTTCCCATTGATTCATTGGTGGTGGTTAATGATACCACGCTGCAGCCCGTGAGCTCCTCCAGCGCTGTTGCCACCGCTGTGTCCAAGACACGACGTAGTGCCAAACAGACGACTGGAACAGCAGCTGTAACGGGAGCAGGAGCAGCAGATGAATGCAGCAAGAGCAGTGCGTCAGGTAGTCGCACCAGCAGTCGCCGGAAAACTGCCAAATCCAACAAGAACTCCAGCACAACGACAGCCTCCGCGAGCAGTTCGCGTCCCCGCATGATCCATACGGAAAAGTCACGGGTTAGCGGCGAGAATTCATCGAAACGGGCACGTGGCAGATCCTATGTGACCAGAACAAGCACCAGCGAGAGCAGTCAGCTGGGTATGGTCAAGTCGAGTGGCGTTGCCAGTTCTCGTATTGTGGATGACTATGAGATTATATCACCTGCCACACAGCCACCAAATCAGATCAGCTCCAGTCCGCTGCACATCAAGCAGGAACAGGAGCAGCATCACCATCATCATCATCAGCAGCCACATCGTGTTCCCCTCATGTACGATGACACACATCTGTTGATCGATGCAGAGCTGTTGCGTGAGAAGAACTACGAGAAGTTTAATCCCAGCATTGTCAATGATCTCGAGGAGATCTTACGTAGTCCACTCAAACATGATCGGAATGCACGCCTGCGTTTCACCAGTGAATCCTCGACTACGCCCCAGTTTCTGCCGGAGGAGGAACAGAATTTAATCAAAATTGAGCCTACGTCACCGGATCTAAGGGAAATGGTTGAGAGTCAGCAGCGTGTAAGTGCTACTGGCCACACGACCACGCCCTCTTCCTCCTCATCGTCGGCACGAACCTCCCGTCATCTCCGTCAGCTCACTGCCAATTCTGGTTCACGGACGGCGACCAAACGACACCATCAGCACCATAGCAACAGCAGCAGCAGCATTAGTAGCACTACCAAGACCATGTCCGTCTCCAGCTCCAAGAAATCAACATCATCGTCGCTGTCCGCCAGCAGTAAATCCAACTCTTATCTTGGCTACGGCGTCGTGGACTCGTACAATGTGGGCGTTGCTGCCAATACCAGCTCCTCGGACGTTAGCTCAGGTTTCTTCTCCATCTCCGAGGTCGTATCCGCTGCCGATGCCGCCGACGCAGCCGCCAAGGCAGCAGCGGCCAATAAACCGGAGCGTCGTGCTCGCTGCTATGAGTGTGAGATGTGCTCGGCCAATTTTCCGGATCGTGCTCAGCTGCTGGAGCATGTGCACATACACATTTGA
Protein Sequence: MNNQDYGGIQWIQQHASAVDSETDMLESGAGDSEVTAAYLVNGNATDEDLDHMAAENLIFMARDGQLSEIIAANESGGGTVLITDGGVAYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNANALELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAASIKFEPPQIQRQVDDHFYDQEWPLYQEQEQLQDQTQQVEQEQLTVASQVVQEASYAAVSNVPAPTAARGRISRLKPKEESTQYIVIAEKQTPDELPQFVDCEEPLTVTATSSDANNPTDNGQAMDASRFPVLDDSKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNHSLQEHQKTHQFEESNSEYDPASAGEDSASESEPDQLYGEFYCSECGISFHRQDLLRRHTKQQHKLSMATTMSSNPDAEGSADADVDGVTDVDGDGENTKDTTHCCHTCGKSFPSALELLAHAEIHARLPPFKCVLCGSSFYEEQAIKRHLHTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDSVRGTYHCTVCAADLTTSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHLRAENKDEEDYGSDMDLCDLDMENVDDLFEAAEAVPAKKEKRKRTAGGQAKATPGPTNGISTSALNNNNNNNNTSKPANGNQDRLWEEKFLQANGSGGGTVPASNSLSENFFPIDSLVVVNDTTLQPVSSSSAVATAVSKTRRSAKQTTGTAAVTGAGAADECSKSSASGSRTSSRRKTAKSNKNSSTTTASASSSRPRMIHTEKSRVSGENSSKRARGRSYVTRTSTSESSQLGMVKSSGVASSRIVDDYEIISPATQPPNQISSSPLHIKQEQEQHHHHHHQQPHRVPLMYDDTHLLIDAELLREKNYEKFNPSIVNDLEEILRSPLKHDRNARLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVSATGHTTTPSSSSSSARTSRHLRQLTANSGSRTATKRHHQHHSNSSSSISSTTKTMSVSSSKKSTSSSLSASSKSNSYLGYGVVDSYNVGVAANTSSSDVSSGFFSISEVVSAADAADAAAKAAAANKPERRARCYECEMCSANFPDRAQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00579414;
90% Identity: iTF_00569124;
80% Identity: -