Basic Information

Insect: Drosophila anomelani
Gene Symbol: -
Assembly: GCA_035045905.1
Location: JAWNOO010000007.1:12511594-12513712[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 2.9e-06 0.00025 21.6 0.5 1 23 399 421 399 421 0.98

2 7 0.0002 0.018 15.8 0.8 1 23 427 450 427 450 0.98

3 7 0.071 6.4 7.7 0.2 1 20 456 475 456 479 0.90

4 7 9.2e-05 0.0081 16.8 2.1 1 23 502 524 502 524 0.98

5 7 4.9e-07 4.4e-05 24.0 0.5 1 23 530 552 530 552 0.98

6 7 0.0013 0.11 13.2 0.3 2 23 559 580 558 580 0.96

7 7 0.00026 0.023 15.4 2.2 1 22 586 607 586 610 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	2.9e-06	0.00025	21.6	0.5	1	23	399	421	399	421	0.98
2	7	0.0002	0.018	15.8	0.8	1	23	427	450	427	450	0.98
3	7	0.071	6.4	7.7	0.2	1	20	456	475	456	479	0.90
4	7	9.2e-05	0.0081	16.8	2.1	1	23	502	524	502	524	0.98
5	7	4.9e-07	4.4e-05	24.0	0.5	1	23	530	552	530	552	0.98
6	7	0.0013	0.11	13.2	0.3	2	23	559	580	558	580	0.96
7	7	0.00026	0.023	15.4	2.2	1	22	586	607	586	610	0.91

Sequence Information

Coding Sequence: ATGAGATGTGTGGTGCCCAATTGTAGAAATGCTTCCATAAGCAGATCCAAAAAGGATCAGCAGCCGCCGGTTTCCTTTTTCCAGTTTCCAAAACCCCCGGAACTATTCAACAGATGGCTGTCGTTCTGCAGCGGTTCAGAGAATGCCTTGAAAGTAAAAAATCCGTGCATCTGCATCGAACACTTCCGAGACGAGGATATAGAGGGGTCTATCAAATTCGAAATGGGTCTTGCTAAGAAGAGAACGTTGCGTCCAGGTGCGGTTCCGTGCATAAACAAGAGCCTGGAAAGCCCCTCAGAAAAGGCTCGATTAGAGCGTTCAAAGCGGCGGAGTAACCATAAACTGGTCACCGAACTACTCTTAGAGGATGAGGCCAGATCTATTGCTGCGACAGATGTGGTTCCTACGCCCAACTACGTCCGGTTGAATACGGGAATTGCTTCGGCTCCTCCATTCGTTAGTTCTACGCCGGCAGAAAGTGGGTTAGCTTCTATAATCCTGGAAGACGATCCGCTCGTGGCCGCAGTAAAAACAGAAACGAGGGAGACGTGCCGAGTCTGCTACAAGAAGTTTGTTGTCGACGACAATGCCAAAGATCTCTTTGATCCGGATAACAGTGTGCTGATTTTCCACATTGAAGTCATTAGCGGAGTTTGGATCAGATATATCGAAGGGGAACCCCAGCTCATATGCCCCGCGTGTCAGATGTCCCTTCAGATGGCGATCGAGTTCCGGGAGATGTGTATAAACATCGAGCTGAAGCTCACCCAGCCCAAGCCTGAAATTGATGAAGAACCCGACCTGGAGGCAGTCCAGGAAGAATCATCTGAGCTAGATATTTATTCGGGCTCGGAATATTCCAATCTCGACGAATATCCTCCAGACGATCCTGTGGTGGACGATACCCTCTCCAATACTGACCTAAACCTAGAGTCGGTCGCAGAATCTCCCGATTTGGGTTCACACGATCCCCTCAGTGTGGCCCCTGGAGCCACAATTGTCAAGGATCTAATCAGCCAATATACGGGAAAGTCCATGACAAAgtcaaaaaaagaaacgccCGTTGCAAAGGGGATCGAACCCAATCCTTCTGCCGTGGCTTGCGAAGAGAAACCGAAGAGAATAGCCAACACTAGGACCAAAGAAGAGAGAAATCTTATCCGTCGTGCTAGGATCCGGGCCAGGCCAACGAACTTTGTGTGCGATCAATGCGGCCAGGCCTTTCGCATGGCTCACAACCTGCAAATTCACATCCTGCGGCACACCCGGACCAAGAACTATCAATGCACCGAATGCTCCATGACCTTTTACGATGCCTACATGCGCAACATTCACATCCGAATCAAGCATCGTGGAGAGATGCCCTTTAGCTGTCGATACTGCAAGGCCACGTTCGCCTATGCGGGAGCACGTCAGAAACATGAAGGCGGAGTACATGGAGCACCACCCCGCCGGATCGTGAAACGAATCAATGCTCAACCCATGCCTCGCTCCAAAACGCGCTATCATTGTGAACTCTGCGAGAAACACTACGCCTCCAAGTATGCCCTGGCATGGCACATCAAGTCACACACGGATGCGGGTGCCTACAAGTGTCAGCTGTGTGATAAGAGCTACTCGGATCCTGGCACACTCAAGCGCCATGAGATAACCCACGAGGACAAGAGACCGCTGCAGTGCGAGGTGTGTCTGAAAGGATTCTACCAACAAACGAAGCTCAGAGAGCACGAGCTCATCCATACCGGCGAGCGTCCCTATCGATGCGAAATCTGCGATGTCCACTTCCGCTACAAATACAACATGAAGGTACATGCAAACAGCAAAATGCACCAGGAGAACCTTGCAAAAGCGCAGTCCAATCAAAttgttgaaatttaa
Protein Sequence: MRCVVPNCRNASISRSKKDQQPPVSFFQFPKPPELFNRWLSFCSGSENALKVKNPCICIEHFRDEDIEGSIKFEMGLAKKRTLRPGAVPCINKSLESPSEKARLERSKRRSNHKLVTELLLEDEARSIAATDVVPTPNYVRLNTGIASAPPFVSSTPAESGLASIILEDDPLVAAVKTETRETCRVCYKKFVVDDNAKDLFDPDNSVLIFHIEVISGVWIRYIEGEPQLICPACQMSLQMAIEFREMCINIELKLTQPKPEIDEEPDLEAVQEESSELDIYSGSEYSNLDEYPPDDPVVDDTLSNTDLNLESVAESPDLGSHDPLSVAPGATIVKDLISQYTGKSMTKSKKETPVAKGIEPNPSAVACEEKPKRIANTRTKEERNLIRRARIRARPTNFVCDQCGQAFRMAHNLQIHILRHTRTKNYQCTECSMTFYDAYMRNIHIRIKHRGEMPFSCRYCKATFAYAGARQKHEGGVHGAPPRRIVKRINAQPMPRSKTRYHCELCEKHYASKYALAWHIKSHTDAGAYKCQLCDKSYSDPGTLKRHEITHEDKRPLQCEVCLKGFYQQTKLREHELIHTGERPYRCEICDVHFRYKYNMKVHANSKMHQENLAKAQSNQIVEI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00524598;
90% Identity: iTF_00478049;
80% Identity: iTF_00478049;