Dano000346.1
Basic Information
- Insect
- Drosophila anomelani
- Gene Symbol
- -
- Assembly
- GCA_035045905.1
- Location
- JAWNOO010000007.1:2802284-2808429[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00084 0.075 13.8 0.8 1 23 1324 1347 1324 1347 0.97 2 13 7.4 6.6e+02 1.4 0.2 1 23 1500 1522 1500 1522 0.91 3 13 0.00016 0.015 16.0 2.7 2 23 1525 1546 1525 1546 0.97 4 13 6.3e-05 0.0056 17.3 0.2 3 23 1554 1574 1552 1574 0.98 5 13 5.3e-07 4.7e-05 23.9 4.1 2 23 1581 1602 1580 1602 0.97 6 13 5 4.4e+02 1.9 0.4 5 23 1615 1633 1613 1633 0.96 7 13 1.2 1.1e+02 3.8 5.4 3 23 1640 1661 1638 1661 0.93 8 13 0.13 12 6.9 0.2 2 23 1672 1692 1671 1692 0.96 9 13 5.1e-05 0.0045 17.6 0.4 1 19 1698 1716 1698 1720 0.95 10 13 3.2e-05 0.0028 18.3 0.4 1 23 1728 1750 1728 1750 0.98 11 13 9.5e-05 0.0084 16.8 7.6 1 23 1756 1778 1756 1779 0.96 12 13 0.0002 0.018 15.8 6.5 1 23 1784 1806 1784 1806 0.98 13 13 0.0024 0.22 12.3 6.1 1 23 1812 1834 1812 1835 0.96
Sequence Information
- Coding Sequence
- ATGGTCGACAACAGCGTTCAGTGCCCCGTGTGCACCCTGTACCTGCATGCGGGAATGAATCTCTCCGATCACCTGGAGACTCATCCCAAGGAGCAGGTGATCAAGGCGCTGGTCCAGATGACGATTGTCGGTAGCGGTGGCAACAACAGCATGGGCAGTGCCTTGGCGGCCGCTATGTTGGCAGGAGGCTctggaggcggaggcggaggaggaggaggtggtgggACTGATGGCGGAGAGGCCAGCATGACAGATGATAAGACCGCCTTCCCATTGTCAACACCCTGTGGCGATGTTAAACCAGTTGTGGCCACCCCCCCGCCAGCGATGTCCAAAACCATATCAGCTGCAATGCCCGTAGTGCCGCCAGCACCGCCGTTGCCGCCGCTCTCCTCCGCCAACGCTACACCCTCCTGCACGTCCCCTTctgcaagcagcagcagcagcagtagcagcagtaATCTGAGCAATCCACCGATGAAAGCACTGAAATGCGCACCGCCCACGACTGAGGCGCGAGCCAACACATCCGCACATCCCACCATAAGCAGCGTGTCCACACTGTACCAGCCGTCGCTGGTCGCTCCGGATTATCGCTTcaatcaccagcagcagcagcagctgcagtcTGACTTTGGGCGTGGTGTTGGTGGCCCCAATGCAGGCACGCTGGTAATACCACAGGTTGCGCAGCAGCACTTCCTCACCagccatcagcagcagccccaCTTTacccatcagcagcagcagcaacaacagcagcatcagcagtcGCCCCTGAAGTTTACCTACGCCACCGctctgccgccgccacccCCGCTGCAGCTCTTtacgcagcaacagcagcagccgacgACAGCTTCAACGCAgtcgcagccgcagccgcagcctcACCAGAAACCACCTCCCGCCTACGGAGCCGCCATCAGTCAAATAAGATCTCAGCACAACCAAATCaagcagcagccacatcaacagcagctgcagcagcagtcacAGTCACCCCAGATGACCGGGCAGCACAACTTAAACCTGGCACCACCGaccccaacaacaacagccctTTCGATATCAAAGCAGCCCAGCAAGGCGCATGCGGAAGTATTCCTGAATcccccaccaccaccgccgcaaCAGCCACAGGCAACGGCACCAATTCACGGCCTGGGTCAGCACCAGCCGAATCATCAGGGTCACCCACAGGCCCATCCCCATTCCCATCCGCAACAGCAGgcccaccagcagcagatggCCACATCGCCTTCCTCAAGATTGCAGCATCAGCAGTCACTGAGCTTGCAGACTTACGGCTCGGGCAGCATCTCTACTTGCAACTCTGGATCAGCCGCTGGTCCGGGCAGTCGCGGCAATCGGCAAACTAACTCTCCCTTTGGGGCACTGCTCAACGCAGCGGCAGCTGTAGCGTGCGCGTCGCCAGCCTCGACCAATGCCTGCTCGTCGGTTTTGCGCTTTGCGGAATCACCAGTGGCCCACTATCTGGAGCGGGAGAATGGTGACTTTATTGTCCAGGAGACGCCCAAGCATATTGTGGAGTGTGTGGAGAAGGAGGACGGTGAGTTCTCTGTGATCGAGCGCATTTACCAATCCCCGCCGAGTGTCCTGCACATACACGATGACGATGAGGACGAAGAAgacgaggaagaggaggaggaggacgacgacAAAGCTCAGCCAGAGGAGGAGGTAGACGGAGACGATGAGCGGGAGGAGAATAGCCGCAGTTGCAGCCGCAGCCGTAATATGAATAAGACAACGAAAAAATCGCGGAAGGCCAAGCCCAAGCGAAGCACCAAGCGCGTCTCGGacggggaggaggaggagtttATGAGCATTAGCAGTGGCGAGAGTGAGGCCGACACAGAGCGCAAGTCCGACTCAATAGCCTCGACGTCAACAGCTGCAACACCGCTTTGCACAGGTGCCTCTACCAGCtcggcggctgctgcagccgcCCACTCCATGTCCAGCAATCTCGCGGACACCCATTCCAATTCGGCCTCCAATTCCGCCTCGAACTCCACCTCTACCACGACCAAGTCCAAGAAGAATCGGATAACAGTGCTCAGCGATGTGCCGCTCAATATGAATGAGTACCTCGACTTAATGGGCAACATTGTGGCCTCCAGTCGCATTGGGGCTGGGCGCCCATTTGCCGCTGTAGTTCCCATTCCCTTTGTCAAggtggagaaggaggagcCCCTAGATGAGTACGACGACAATGAGGCAGCGCAGCAGTTAGAGCAGAAGCCTAGCTTGGAGCACGGCACCACCAGTGTCATTCGCATGGCCAGCACAGTGACAGCGACGGCAACGACACCGGTGACTGAGGAAGCACCTGTCGAGGATCCCAACGAGCCACCGCTCATGAAGGTCGAGGTGGAGCCCAACACGATGTTGCTACCGCAGCGCTTCTCCACTCCTGCCCAGAGTCGTGGGCCCAAGAAATTAGTCATCAAACCAAAGGCAACAGCATCAGCTCCAGCGACAGCGACGGCGGCGACAACAAAAAAGACTGACACCTCTCCATCTTCCTCATCAAGCAGCAACGCATCCATATCAAGAGATCTGGGGCAGGTGCAGGTAAAAAGTGAGACTCCGGAGGCTCCggcagcaagcagcagcagcagcattctGGAGAAGCACCTAACTACCAGCCGCAACCAGACCCAGCACCACCATTCGGCTGTCAACGATGACGATGCCCGCGTGCTGCTGGAGTTTGCCAACTCCAAGCAGCCGCCACCGCCGGCAGCGTCCAGCACCACGTTTGTGGTGAATGCCAGTACGGGATTCCCATCGGCCGGGTCCGTTTtcgccagcagcaacagcactACCACCAGCAGTACCAAGGCGGCGACAAAGCCTGGCGAGGAATACATTCTGCCGGACAACACCAACTTGGATGTGGATGAGATTGTGATATCCTCGTCGTCTTCCTACGCCTCCTCAGCGGCTCAGGTGCAGGCAGCTCTGCAGCCGCCGGACTTTAACTTCCTTTACCACCAGACCACCAGCACAGCCACTGCGGCCAACTATCCCTTCAATGCCTTCTCAaggcagcaccagcagcagcagcaacaacaacaacaacacggTGTTAGCGATGCCACCAATGCGGCCACCTTGGCCTCCTCTTCCAGCAATTCCATGGACCACGACTCGATGAATGCCTCCTTCCGTGTGGCCAAGACGCAGTCGCTGCAGTGGTACCAGCAGGAACAGGAGAACGATCCACAGATCCAGGCAGAAGGAGCCGGCGCGTCGGGGGTGTCCTCCAACCAGAGCCACACAGATGTGGTCAGTCACCAGCCCACCAACTTCAATGCCGCCCTGGCGGCTGTCGATTGCTGCAGTGTTGCGGCAACGCTAGACGAAGAAGCCAAGTATTTGGACTTGGATACCTGCAAGCGGGAGCAgctaagcagcagcagcaacctgCCCTCAGCTTCCGCCTCCACATCTACCACCTCATCCTCGTTCGCCGGTGCTGGCACGGAGAGCAGTTTAGTGGGTGGCCTCAACATTCGCACGGATGAAAAGATGCCCGCCAAGGGTGAGATCTCCGAGCAGGAGAGCAACTGTGACATTGAAAACTCGTGGAGTGAGTCGGTTTACGGGGACATTTCGCAGCGGTACTTTAGGAACCACTTCTCTGCAGGCTACAATCCTGACTGGCGACAGGACTACTACCCGGCTCAGGATCTCAGCAGCGCCCAGCAGAGGGAACAAAAGCGCTTCGACTTCAATGCAATTGATGATGAGGCCTCATCCAGCTCTAGGAAGAGCCAGCTAACGGATATCGTCCCAACTGTGGCCACCTCCCCAACTTCCACGTCATCGGCTTTGCTGGCGGGTCCACCAATAGCTTCGACATCTAGGGCTGCCGCGGAGGCGGCAGCAGAGGCGGCGGCTGCTCTTGCCCAGCGAAAAACACATCGCCGCAAGCTTTACAAGTGCCCCCATTGCGATACCGTCTACGAGAAGCTCAAGGAGCGGAATGCCCACATGATTAGCGAGCATAACTATGTGCGTCAGAATCGACGACTCATCTGTACCCAGCCGCAGGTCACTGAACCGATGCTGCCCCAGCATCATGCCCAGTTGCTGCTGCACACGGACGCGGCTGTGCAGGAAGACTCAAAGGATGGCATTGTGAAGATCAAGCAGGAGCAGTGTTCGGAAAAACCGGAAGTGGAGCAACTGCATCACTCGAATTCTGCTGAGTTGCTGTCGGATGTCAAGGACTCTGAACTTCTGGGCATCGGTGGCGAGGGCGATGGAGACTTGGACGGCGATATTAAGCCACCTAGCCAGCTATTTGAAAAGTCCTCACCATTACCGCCGCTGGCCATGACAACGCCGGCTGCAAAGCTTGCGGCGCTTTACCGCATGCTTATCGCCTACAATGAATCGAAGCTGGGCCAGGAGCGCAACAACCTCAACGAACTGGAGCAAAAGGCCATGGAGAAGTCCATCTTCCTGTGCTATGTCTGCCGCACCGACTTCCCCTCCGTTAAGCTTTACGACGCCCATCTCACCGAGCACCCGGCCGAGTGTTTCACCTGCGGCAAGAAGTTCTACCGCTGGAAGAACTTCTCCCTTCACCTGAAGCGGCACCTGGGCTGGAAGGAGTTTGGCTGCTACGTGTGCGACAAGAAGTTTGTGGTGCGGAGCGCCCTCGTCGAGCACATGCGGATGCACACGGGCCAGACGCCGCTCAAGTGCAAGATATGCGGTAAAAAGTTCAAGCGCTACTCGAATCTGACGCAGCACCGCAAACGGCACACCAAGGTGATGGTACGGAAGAAGGAGTACGTGTGCCACTGTGGCGAGGTTCTGCCCTCAAAGGCGCGCTTCCTGTGGCACAAGGAGACGCACGACCTGAAGCCGAAATGCTGCCCGTATTGCTGTGACCGCTTTGTGCACGCCAACTCGCTGCGCCGCCACATCCGGCTGGCGCACTCGGACAAGTTTGACTACGCCGAGCCGATGGAGTGCCCCATGTGCAAGCAGATCTTTGCCAAGACATCGATCAAGGCCCACATGGCGACGCACTCGACGGAGCCGCAGTACGACTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATCCACTCGTGGGTCCACGCCAATCGGACGGCCAAACCCTTCAAGTGCGAGTACTGCCCGAAGGCGTTTGTGCGCGAGCTGGACTTCAAGAACCACATCAACGCGCACAAGCAGATCAAGCCGTACACGTGCGAGTACTGCGGTTGCAAGTTTATCCGCAAGTACAACTACATGCGGCATCGCCGCGAGCACCACGGCACCAAGAAGTTCACCTGCGACCAGTGCGACAAGTCCTTCCATCGGCATTACTATCTGATCGAGCACCGGCGCATGCATACCGGCGAGCGACCGTTCACCTGCACCATTTGCGGCAAGAGCTCCACCACCAAGACCAACCACAACAAGCATCTGAAGATCCATCATTCGCGCGACCCCTTCACTGTGGAGGTCTAA
- Protein Sequence
- MVDNSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGSGGNNSMGSALAAAMLAGGSGGGGGGGGGGGTDGGEASMTDDKTAFPLSTPCGDVKPVVATPPPAMSKTISAAMPVVPPAPPLPPLSSANATPSCTSPSASSSSSSSSSNLSNPPMKALKCAPPTTEARANTSAHPTISSVSTLYQPSLVAPDYRFNHQQQQQLQSDFGRGVGGPNAGTLVIPQVAQQHFLTSHQQQPHFTHQQQQQQQQHQQSPLKFTYATALPPPPPLQLFTQQQQQPTTASTQSQPQPQPHQKPPPAYGAAISQIRSQHNQIKQQPHQQQLQQQSQSPQMTGQHNLNLAPPTPTTTALSISKQPSKAHAEVFLNPPPPPPQQPQATAPIHGLGQHQPNHQGHPQAHPHSHPQQQAHQQQMATSPSSRLQHQQSLSLQTYGSGSISTCNSGSAAGPGSRGNRQTNSPFGALLNAAAAVACASPASTNACSSVLRFAESPVAHYLERENGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDDDEDEEDEEEEEEDDDKAQPEEEVDGDDEREENSRSCSRSRNMNKTTKKSRKAKPKRSTKRVSDGEEEEFMSISSGESEADTERKSDSIASTSTAATPLCTGASTSSAAAAAAHSMSSNLADTHSNSASNSASNSTSTTTKSKKNRITVLSDVPLNMNEYLDLMGNIVASSRIGAGRPFAAVVPIPFVKVEKEEPLDEYDDNEAAQQLEQKPSLEHGTTSVIRMASTVTATATTPVTEEAPVEDPNEPPLMKVEVEPNTMLLPQRFSTPAQSRGPKKLVIKPKATASAPATATAATTKKTDTSPSSSSSSNASISRDLGQVQVKSETPEAPAASSSSSILEKHLTTSRNQTQHHHSAVNDDDARVLLEFANSKQPPPPAASSTTFVVNASTGFPSAGSVFASSNSTTTSSTKAATKPGEEYILPDNTNLDVDEIVISSSSSYASSAAQVQAALQPPDFNFLYHQTTSTATAANYPFNAFSRQHQQQQQQQQQHGVSDATNAATLASSSSNSMDHDSMNASFRVAKTQSLQWYQQEQENDPQIQAEGAGASGVSSNQSHTDVVSHQPTNFNAALAAVDCCSVAATLDEEAKYLDLDTCKREQLSSSSNLPSASASTSTTSSSFAGAGTESSLVGGLNIRTDEKMPAKGEISEQESNCDIENSWSESVYGDISQRYFRNHFSAGYNPDWRQDYYPAQDLSSAQQREQKRFDFNAIDDEASSSSRKSQLTDIVPTVATSPTSTSSALLAGPPIASTSRAAAEAAAEAAAALAQRKTHRRKLYKCPHCDTVYEKLKERNAHMISEHNYVRQNRRLICTQPQVTEPMLPQHHAQLLLHTDAAVQEDSKDGIVKIKQEQCSEKPEVEQLHHSNSAELLSDVKDSELLGIGGEGDGDLDGDIKPPSQLFEKSSPLPPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLNELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKVMVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTEPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHINAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGTKKFTCDQCDKSFHRHYYLIEHRRMHTGERPFTCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00590408;
- 90% Identity
- iTF_00613125;
- 80% Identity
- -