Dano001388.1
Basic Information
- Insect
- Drosophila anomelani
- Gene Symbol
- -
- Assembly
- GCA_035045905.1
- Location
- JAWNOO010000007.1:10573275-10576451[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 3.8 3.4e+02 2.3 0.8 8 23 189 205 179 205 0.63 2 13 0.0065 0.58 11.0 0.6 1 23 211 234 211 234 0.97 3 13 4.4e-05 0.0039 17.8 6.2 1 23 239 262 239 262 0.95 4 13 4.8e-05 0.0043 17.7 2.1 1 23 267 289 267 289 0.98 5 13 4.8 4.3e+02 2.0 3.8 2 23 296 319 295 319 0.91 6 13 0.00063 0.056 14.2 3.9 3 23 330 351 329 351 0.95 7 13 0.0049 0.44 11.4 0.2 1 23 357 380 357 380 0.95 8 13 0.012 1.1 10.2 0.1 2 23 391 413 390 413 0.93 9 13 0.00019 0.017 15.8 0.3 1 23 441 463 441 463 0.97 10 13 8.4e-06 0.00075 20.1 4.0 1 23 470 492 470 492 0.97 11 13 0.00023 0.021 15.6 0.1 2 23 499 520 499 520 0.97 12 13 0.00049 0.043 14.6 0.8 1 23 527 549 527 549 0.99 13 13 0.00023 0.02 15.6 3.2 1 23 555 578 555 578 0.97
Sequence Information
- Coding Sequence
- ATGGAAACGTGTCGTACCTGTGCGATTTCCATGTTTGTGTGCGATTTTGAAAATGGCAGCAACAACTTCCTGGACCTCTACCATTCCAACTGCTGGCCAAGCGAGATGGCCCAAATTCGCCAGCAGTTCCTCAACTGGAATCTAAAGatCTCACCTAATGACGGACTGCCCCAGAAGATTTGTAGCGACTGCTTTACCAAGTTCTGTTCCATCAATTCTTTCCAAGTGGCCTGCCAGGAGGCGCAGGTGAAGCTATCCAACATTTACGACAAAATCGATGCCAGCAGTTTGGAGGATGGGCAGCAAGAGGACTCAGACCATGCAGAGGATCCTCAAGGTCCTGAAACAAccataataacaacaacaacgacggTTTCAGACGAAACACAACCAACAAACACTGCCACTGAACCCATACAGTTTTTTGTGGATGCCCTAGACATCGAAGCAGAAGCTGCAGAGGAAGAGGGATCGGAAGCAAAGACGGAGGAGCAATCACCGGAGGAATCTGCCCCCCCGGAACTGACCATTAGCTATGCCTGCAAGTTTTGCCTGCAGCCACAGGAGAGCTATCAGCTGCAGCAACATTTACTGGAGCACATCAATACCAGCCACGATCCGGAGCAGCCGTACAATTGTCCGGAGTGTGAGGCGCGATTTCAGGATGCCGCCTCCCGGACTGTACACCTCAAGAGCTGTCACGTAGAGAAACAGCACACCTGCGAGGTGTGCGGCAAGAAGTACAGCGATCGGCACAATTTGCGGCACCACGTCGAGAAGTACCATTCGGAAACGGACTTTGAGTGCGGACTGTGCGAGAAGCGTTTCTTTACGCGGAAGAGCCTCAACTATCACATGAAATGGCACAATCCGGAGCGGCAGCTCAAGTGCCGCCAGAGCGGCTGCGAGCGTTTGTTCATCAGCCAGCGGCACCTCAAGTGTCACGAGGCCACGCACACGGGCACCAGTGCCAGGAAGAGCGAGCATTGCGGCTTCTGTGGAAAGACTTTTATACACCTGAAGACCCTTCGCTGGCACATCTACAGGCAACATGGCGGCGAGAAGCCCTTCAAGTGTGCCAACTGCACGGAGGTTTTCGCTTCATATGCGGAGAAGCGGATCCATATGCTGGAGCAGCACAGGGAGAATTTGACGGCCATCGAGCGTAGTGAGTGTATGCTGTGCCGCCAGGCCTTCACCAGTGAACAGGATCTGGTCCTGCACATGTCAGGCGAGCACTTGCAGCACGCCGGTGCTCCAGTGATTGCCAACAATAAGCGAGTGCTCCAGCAGAAGCGGGAGCGCCAGTATTCCGGACTCTTCCAGTGCGACAGCTGCACCCAGCGATTCAACATGAAATCGGCACTGGAGCGGCATGCAGCTGTTCATTCGGAAAAGGATCGACCGCACGCTTGCCCGCATTGCTCGAAGAGATTCAAGCGGGCCCAGGACATGAAATGGCACATCAAGACGCACGAGAAGGAGAAGCCCAATGTGTGCGATGTCTGCGGCAAGGCCTTTGCCCTAAAGTACGTGCTCACGCAGCATCGCTTAAGCCATGAGATCTTGGAGAAGAACTTTAAGTGCAATGTTTGCGGTCGCGCCTATCTGTTTGAGAAGTCTCTGCGGCTCCATCAGCGGGTTCACACAGGCAAGACCTACTATAAATGCGATCTCTGCCAAGAACGATTTGTCACGCACATCAAGTTGAAAACTCACATGCAACAGACACACGCCTCACAGCCGAATATAGCTGATCCTCTGGATGATTTGATAAACATTGTGATTTCCTAG
- Protein Sequence
- METCRTCAISMFVCDFENGSNNFLDLYHSNCWPSEMAQIRQQFLNWNLKISPNDGLPQKICSDCFTKFCSINSFQVACQEAQVKLSNIYDKIDASSLEDGQQEDSDHAEDPQGPETTIITTTTTVSDETQPTNTATEPIQFFVDALDIEAEAAEEEGSEAKTEEQSPEESAPPELTISYACKFCLQPQESYQLQQHLLEHINTSHDPEQPYNCPECEARFQDAASRTVHLKSCHVEKQHTCEVCGKKYSDRHNLRHHVEKYHSETDFECGLCEKRFFTRKSLNYHMKWHNPERQLKCRQSGCERLFISQRHLKCHEATHTGTSARKSEHCGFCGKTFIHLKTLRWHIYRQHGGEKPFKCANCTEVFASYAEKRIHMLEQHRENLTAIERSECMLCRQAFTSEQDLVLHMSGEHLQHAGAPVIANNKRVLQQKRERQYSGLFQCDSCTQRFNMKSALERHAAVHSEKDRPHACPHCSKRFKRAQDMKWHIKTHEKEKPNVCDVCGKAFALKYVLTQHRLSHEILEKNFKCNVCGRAYLFEKSLRLHQRVHTGKTYYKCDLCQERFVTHIKLKTHMQQTHASQPNIADPLDDLINIVIS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00491676;
- 90% Identity
- iTF_00491676;
- 80% Identity
- -