Dano002278.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila anomelani
Gene Symbol
-
Assembly
GCA_035045905.1
Location
JAWNOO010000007.1:17542827-17544773[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.00027 0.024 15.3 5.0 2 23 140 161 139 161 0.98
2 9 6e-07 5.4e-05 23.7 3.1 1 23 167 189 167 189 0.99
3 9 4e-07 3.5e-05 24.3 1.0 1 23 195 217 195 217 0.99
4 9 5e-05 0.0044 17.7 3.5 1 23 278 300 278 300 0.99
5 9 1e-06 9.1e-05 23.0 0.9 1 23 306 328 306 328 0.98
6 9 3.2e-06 0.00029 21.4 5.6 1 23 334 356 334 356 0.99
7 9 4.7e-06 0.00042 20.9 1.0 3 23 490 510 488 510 0.98
8 9 6.3e-06 0.00056 20.5 0.5 1 23 516 538 516 538 0.99
9 9 1.2e-07 1e-05 25.9 2.2 1 23 544 566 544 566 0.98

Sequence Information

Coding Sequence
ATGCATCTGAACCATGCGACTGCCACCACAGCAGCCATGGCCAACTACCAGCACTACCAGCTGCCAGCCTCCcatggtggtggcggcggcgcaGGCGGTGGCGGAGGAGGGGGCAACGGCGGTGGGGGTGGAGCTGGCCTGCAACAGCCCACGACGCTGGCCAGCCTGCAGCAAAGCCCCTTCGCCCTACATCAACTGACTGCGGTGCAGGCCATCCAACATCCCACCCACCAGGCAATGCTCCATCCACAGCACCCGCTGGTCCATTTGCTGGACATTTCCACGACCACGGCGAATAgtggcggcagcggcaacggAGGCGCGGGAAATCATACGCCGATTTCGCCCATGAAACAGGAAGTTCAGAGCGTAATTagcgaggaggaggtggtggtggaTGATCCGCGCAAGAAGAAGCAGTGCCACGTGTGCAAGAACAAGTTCCGGCAGCTGACCACGTTACGCAACCACATGAAGATCCACACGGACGAGCGGCCCTACAAGTGCAAGCACTGTGACAAGGCCTTCCGACAGATCTCGACGCTGACAAACCACGTGAAGATCCACACCGGCGAGAAGCCGTTCACCTGCAACATCTGCGCCAAGGACTTTCGCCAGCAGAGTACGCTGATTAACCACATCAAGACGCACAAGGCGGCAGAGTCCAGTACGCCCACGTCCCTGCTGAATTATCAGCCGCAGCCGGGCAGCGGCAAGCATCGAAAATCGCAGATGCAGgtctaccagcagcagcatcagcgcGTCCAAATCTCAAAGACCCTGTACTCCGGTAGCTATAGCTCTCCGGCGGCAGAGGAGCTGGTGAAGCCGTATCAGTGCAGCGTCTGCAAGCGCCGCTTCCCGCAACTGACCACGCTGCACAACCATGAGCGGACCCACATCGATCCCAAGCCCTACAAGTGCGAGACGTGCGACAAGTCCTTCAGCCAGCTGGCGACACTGGCCAACCATAAGAAGATCCACACGGGCGATAAGCCGTACACGTGTTCCTACTGCCACATGCAGTTCCGCCAGCAGAGCACCCTCACCAACCACCTCAAGACGCATACGCATCAGATAGCCGGCGCTGGCGGTGGAGCAGGAGGACCTGGAGGATCAgcaggaggcggcggcggaggcgccGTAACAGCCACAGTGGATCACGCAATGCCCCCAACCCTGGCGCCCGGGACGCAGCAGCTGACGACTGGACTGTTGCCGAACAACCTGCACGGAAACACGCCAAACATCATCCAGCTGGACCATCATCCGCTACTGCATTTCCTCGATGGCAGCACCACGGTCAGTTCGGTGGTGGCAACGGCGGCGGCTGTCACCAAGGTTGAGCACTTCCAGCCGGGCGCAAgcggcggtggaggaggaggaggaggatcgCCGCCGGGCCGCATGACCATTGTGGGCAACATCAATATGCTGAAGGGCGACAATCCGGATAGACCGTTCGGCTGCAGCGTTTGCCAGCGGTTCTTCTCGCAGCAGAGCACCCTGGTCAATCACATCAAGACGCACACGGGCGAAAAGCCGTACAAGTGCAAGATCTGTGAGGTCAACTTCCGGCAGGTGGCCACGCTTAACAACCACATGAAGATCCATACCGGGGAAAAGCCCTACAACTGTTCCTACTGCCCAAAGCAGTTTCGGCAAAAGAGTACGCTGCAGAACCACCTCAGGGTGCACACCTGTTAG
Protein Sequence
MHLNHATATTAAMANYQHYQLPASHGGGGGAGGGGGGGNGGGGGAGLQQPTTLASLQQSPFALHQLTAVQAIQHPTHQAMLHPQHPLVHLLDISTTTANSGGSGNGGAGNHTPISPMKQEVQSVISEEEVVVDDPRKKKQCHVCKNKFRQLTTLRNHMKIHTDERPYKCKHCDKAFRQISTLTNHVKIHTGEKPFTCNICAKDFRQQSTLINHIKTHKAAESSTPTSLLNYQPQPGSGKHRKSQMQVYQQQHQRVQISKTLYSGSYSSPAAEELVKPYQCSVCKRRFPQLTTLHNHERTHIDPKPYKCETCDKSFSQLATLANHKKIHTGDKPYTCSYCHMQFRQQSTLTNHLKTHTHQIAGAGGGAGGPGGSAGGGGGGAVTATVDHAMPPTLAPGTQQLTTGLLPNNLHGNTPNIIQLDHHPLLHFLDGSTTVSSVVATAAAVTKVEHFQPGASGGGGGGGGSPPGRMTIVGNINMLKGDNPDRPFGCSVCQRFFSQQSTLVNHIKTHTGEKPYKCKICEVNFRQVATLNNHMKIHTGEKPYNCSYCPKQFRQKSTLQNHLRVHTC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00504822;
90% Identity
iTF_00565509;
80% Identity
-