Basic Information

Insect: Drosophila anomalata
Gene Symbol: PRDM1
Assembly: GCA_035046425.1
Location: JAWNNY010002097.1:547713-552357[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 2.8e-05 0.0024 18.4 2.5 1 23 913 935 913 935 0.99

2 5 8.3e-06 0.00071 20.1 5.1 1 23 941 963 941 963 0.98

3 5 1.7e-06 0.00015 22.2 4.3 1 23 969 991 969 991 0.98

4 5 0.00058 0.05 14.3 2.4 1 23 997 1019 997 1019 0.97

5 5 9.8e-05 0.0084 16.7 0.1 1 22 1025 1046 1025 1046 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	2.8e-05	0.0024	18.4	2.5	1	23	913	935	913	935	0.99
2	5	8.3e-06	0.00071	20.1	5.1	1	23	941	963	941	963	0.98
3	5	1.7e-06	0.00015	22.2	4.3	1	23	969	991	969	991	0.98
4	5	0.00058	0.05	14.3	2.4	1	23	997	1019	997	1019	0.97
5	5	9.8e-05	0.0084	16.7	0.1	1	22	1025	1046	1025	1046	0.96

Sequence Information

Coding Sequence: ATGCATGGACACCACCACACTCATCTgcaacaacaccagcagcagcagcagcagcaacaacagttgTCACAGAACCCACAGGGACAGGAGCCGGGAGCCGCCATGATGAAGGCAGCGAATCATCCACTCAGCCATCCCCACAACCATGCCCAGTCCCACCcacatccccatccccatccgcATCCACACCACAAGCTGTCGTCAGCGAGAAGGGCGCGCAGTCGCAGTCGAAGTCGCAGTCCGACGCCGGACGGCAATCAGGACTACGATGTGACCAGGATGCGGGAGGAGGACTTCCAGCGCCTGGCCGTCTACCTGGTGCCGGATGTCCAGGCCGAGCGGGGGCTACCCAATCGGGCGGACAAGACGCTGCCCCGCAGCCTTACGCTCAAGTCATCCATGGTCTACTCAACGCCAAATGTTAAGACTGAAGGAGTTTGGAGCAGCGGTGTCATCCCACGAGGCACTCGCTTTGGCCCATTCGAAGGCATTCCAACCTCAAACTATCCCAATGATAAGAATAAGGCGCGCTATTTCTGGCGGGTGCAGGGAACACGCCACATAACCTACGGGAATATTAAGATCTTCAAGGACGATGACTACTACTATCTGGATGGCTCGGATCGCTCGCAATCCAACTGGATGCGGTACGTGGCCTCCGCCTACAGCCTGTCGGTGATGAACCTGGTGGCTTGCCAGCACCAGGAGAACATCTACTTCTACACCACCCGCGACATCCTGCCCAACGAGGAGCTGATGGTGTGGTACTGCAAGGACTTCGCCAGTCGGCTGGGCTACGACGTGGATCCCGAGCGGACGATCTTCGGTGCCTGCAAGCAggcggtggaggaggaggtggacgaggaggaggaggaagcgGATCCGGATGCGGATGAGCGGGAGGAGGTCGAGGGTGAGGGTAAGCCGCATTACTCCATGCCGGCTCCCGAAATCCCCGCCGAGGTGGCGGTGAGCCATATCACCTACGTGATGGGCCTCCATCTGCCGGTGGGTGCGGGAGGTGCTCCCGGAGCCACGCCCCCTCCATCAGGCAGTTCAACGGGCAGCGGCCAGTGCTGCCGCCGCTCCAGTCCACCCGCCCATGTCAGCACCACCTCCTGCAActcgcaccaccaccagcagcaccaccaccaccacccccacatCCAGCACGCCAGCCGCCACGCTTCGGTGATCATCGGACAGGATCGATCGCCGATGGCCAACAGCGACAAGGACACAGCGGGATCTCCGCTGTCCGGGCTGGACCACCAGATGACCCCACAGGACGGCAGTGTGCGATCGGTGCGCTCGGACGAGGGCTACCACAGCAACGAGTGCCACGAGGATGGCCTGACCCCGCCCGAGGACTCCAGCGACAGCGAGAGCGAGCACAACTATGTTCTGGACTGCTCCAAGAAGGCGATAGCCCCCAAGGAGACAGTTATTGCCCAGGCCCAGAAGCCGGGCTGCTCTCCTTCGGCAGTGACGGTCCTGACCAACACCACTTCGACGACGACTACCGCCTCTCTGGGCCACAGCTCACCCACTACCACGCCCTCTTGTGAGACAGACAAGAACGAGTACCGGAAGTTCAAGGTCAAGATGCCGCTGAAGTACGAGTTCAAGAACAAGAGCTGCGTGAAGCAGGAGCCCAGTCTGAAGGAGATGGACCAGGAGATGTCCCTGCCgccagaggaggaggaggagcactCTATGCACCCAGAACCCGATTCCATCTGCCCCTCGACCACCACCCACCTGGGGGATGAGCATTTAATGATTCTGGAGCGAGaaagggagagggagagagagcgCGAGAGGGAGCGAGAGAGGGAGCATCAGTCCAACCAGCAGCCCGCCTCCTCGACGGTGATTGTTCTGGAGCATGGTGGCCCCCAAACCCGCACCATTGTCCCTCTGAGCAAGCCCTACTACGAGGCCGATCCCCCGGGAGAGCGCTATGTGAGATTCGGACAGCCCAGCTCCAGCATTCTGGAGACCATCCTCACCAGCCAGCACCGTCTGGAGGCAGCTGCGGCAGCAGCCAATGCTTGCCGTCAGGCCAacgctgccacgcccccgcccACCTCGCCCACGGAAATGGCCTACAGCTACAAGAAGTCGCAGCGTTACGGCAATGCCGTGAGCCCAGACAGCAGTTCCAATCTGGGCCAGAATCCCGAGCAGCCAGGCGGTGGAGTTGGAAGTGGAGCCAATGGAGTTGTGGTGGTCAGTGATCCGGAAATGACCAGGGCCACCCTGATCAAGGGAGAGTGCTCGCCACCACCGCCCAGCCACCATCACCACAATGTGATCTTCTCGCCGTCGCGGCATGCCGCTTATCTGGGAGCCAGCGATGCAGGGGGTCACTCCCCGAGTCCCGGGTACCCGGGATATCCTCACTACGGAGCGGCGGCCACCTCCACGTTCCACTCGCCGCCCCACAGCTCTCATTCCCCCTTCGACCGCCAGTCGAACGCCTCGAGCGGCGCTGGTTCCGCCTCCAATTTGCATTTGCTGCAGAGTAGCACCCAGATGTTGAACCACCCGCTGATGCAGCCACTTACCCCGCTGCAGCGCCTGTCGCCCTTGAGGATCTCCCCGCCCAGCAGCCTGAGTCCGGACGGCAATTCCTGTCCTAGGAGCGGCAGCCCCCTGAGTCCCAACTCGCTGGCGTCCCGCGGCTACCGATCCCTGCCCTATCCGCTGAAGAAGAAGGATGGGAAGATGCACTATGAGTGCAATGTGTGCTGCAAGACATTCGGGCAGCTGAGCAACTTGAAGGTCCACCTACGCACCCATTCCGGGGAAAGGCCCTTCAAGTGCAACGTCTGCACGAAGAGCTTCACCCAGTTGGCGCACCTGCAGAAGCACCACCTGGTCCACACCGGCGAGAAGCCGCatcagtgcgacatctgcaAGAAGCGCTTCTCGAGCACCTCCAACCTGAAGACCCATCTCCGGCTGCACAGCGGCCAGAAGCCGTACGCCTGCGACCTCTGCCCCCAGAAGTTCACCCAGTTTGTCCACCTGAAGCTGCACAAGAGGCTGCACACGAACGACAGGCCGTACGTGTGCCAGGGATGCGACAAGAAGTACATCAGTGCCTCGGGTTTGAGGACACACTGGAAGACCACCAGTTGCAAGCCCAACAatctggaggaggagctggccaTGGCCGCAGCTGCCACATCGGAGTGCTTGGACAAAGACCACCCCGAACCGGATTCCCGGGAGGCGTacgagcaactgcagcagcacaTGCATCCTGCTGTGCATCCTGGCTTGAGGCATCTCTCCAATGGCGGTCAGTCGCCTCCCCGTTTGATACCCCTGGGTAGCCACATGCcgccacaacaacagcagcagcagcatcagcaacaacagcagcagcagggccTGCCCCCGCCCCACCTTCTCATGGGCCAACATCCGGGCGTGGGTCCAGCCACCATGCTGCTGACCACCGCCAGCCAGCTGCCACCTCCACCGCCGCACCACCAGCAGAACTCCCCCAGCAGCCGGCTGCTGCAACATGCCCACCCACATGCCATGCAAcaaatgcaacagcagcagcagcaacactcCCCCAAGGGGCTCAAGTCGCTGCCCGAATCGGGGGTGTATCTGCATGGAGGTCATGTGCAGGCCCAGGAGAGCAGGCCCTCGGTCATCGAGTCCTCCAACCAGCCGATGATCATCGAGTGCACGTAG
Protein Sequence: MHGHHHTHLQQHQQQQQQQQQLSQNPQGQEPGAAMMKAANHPLSHPHNHAQSHPHPHPHPHPHHKLSSARRARSRSRSRSPTPDGNQDYDVTRMREEDFQRLAVYLVPDVQAERGLPNRADKTLPRSLTLKSSMVYSTPNVKTEGVWSSGVIPRGTRFGPFEGIPTSNYPNDKNKARYFWRVQGTRHITYGNIKIFKDDDYYYLDGSDRSQSNWMRYVASAYSLSVMNLVACQHQENIYFYTTRDILPNEELMVWYCKDFASRLGYDVDPERTIFGACKQAVEEEVDEEEEEADPDADEREEVEGEGKPHYSMPAPEIPAEVAVSHITYVMGLHLPVGAGGAPGATPPPSGSSTGSGQCCRRSSPPAHVSTTSCNSHHHQQHHHHHPHIQHASRHASVIIGQDRSPMANSDKDTAGSPLSGLDHQMTPQDGSVRSVRSDEGYHSNECHEDGLTPPEDSSDSESEHNYVLDCSKKAIAPKETVIAQAQKPGCSPSAVTVLTNTTSTTTTASLGHSSPTTTPSCETDKNEYRKFKVKMPLKYEFKNKSCVKQEPSLKEMDQEMSLPPEEEEEHSMHPEPDSICPSTTTHLGDEHLMILEREREREREREREREREHQSNQQPASSTVIVLEHGGPQTRTIVPLSKPYYEADPPGERYVRFGQPSSSILETILTSQHRLEAAAAAANACRQANAATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQNPEQPGGGVGSGANGVVVVSDPEMTRATLIKGECSPPPPSHHHHNVIFSPSRHAAYLGASDAGGHSPSPGYPGYPHYGAAATSTFHSPPHSSHSPFDRQSNASSGAGSASNLHLLQSSTQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDHPEPDSREAYEQLQQHMHPAVHPGLRHLSNGGQSPPRLIPLGSHMPPQQQQQQHQQQQQQQGLPPPHLLMGQHPGVGPATMLLTTASQLPPPPPHHQQNSPSSRLLQHAHPHAMQQMQQQQQQHSPKGLKSLPESGVYLHGGHVQAQESRPSVIESSNQPMIIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00476215;
90% Identity: iTF_00539186;
80% Identity: -