Basic Information

Insect: Drosophila anomalata
Gene Symbol: Glis3
Assembly: GCA_035046425.1
Location: JAWNNY010000840.1:144778-149715[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.054 4.6 8.1 0.3 3 23 409 432 407 432 0.89

2 5 0.16 14 6.6 0.4 1 23 441 468 441 468 0.88

3 5 1e-06 8.6e-05 23.0 0.5 2 23 475 498 474 498 0.97

4 5 0.00081 0.069 13.8 0.8 3 23 506 528 504 528 0.92

5 5 3.3e-05 0.0028 18.2 0.4 1 23 534 558 534 558 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.054	4.6	8.1	0.3	3	23	409	432	407	432	0.89
2	5	0.16	14	6.6	0.4	1	23	441	468	441	468	0.88
3	5	1e-06	8.6e-05	23.0	0.5	2	23	475	498	474	498	0.97
4	5	0.00081	0.069	13.8	0.8	3	23	506	528	504	528	0.92
5	5	3.3e-05	0.0028	18.2	0.4	1	23	534	558	534	558	0.94

Sequence Information

Coding Sequence: ATGTCGTCTACGCTGAAGATTGCCAGCCAAAACGGCGGCATGTACGTCAAAACATCGGAGATTTCGGGGAAGGCAGGTCCCTGCTATGGGGGCTTCATGTCGCCCCCGCTAAGTGCGAATATGTGCTCGGCAGCTGGAGCAGATCGACAGACTTTCCGAGTGCCGGCCAAAGTTGAACCAGGAACCGCACATAACAACTTCGTGTCCGGTGACTTGCAATTCCCAGACTTTTCGCACCTTTGCTTTGCCGCCGAGACCCCCAACTCGGTGTTCAGCGATTGCAACAACTACGCCGGACAGGATCAGCAGCAGGACTCGGATCAGGATGATATAGTGTGTGCGGCAGCGGGCAACACCGGTATTCTACCCTATCAACAAGGCCAGTATACGCAGCTTAACCGCGAGGACATCTTCCGCTTCGAGCCGGAGGATATAGCACGTCTTACTGGAGACTCCGCCGATTTTAACGGAATGCCGCCACAAACTCCATACACCCCCTACACCCCATATACGCCGTGCAGCGCCCAAAATACGCAGCTACCCGTGCAAGCTACCTGCGCCGAGTCTATTAATCTGGATATTGATTACTTTAATTATGATGAGATTAATTGCCAATCAAAAAACCAATCTCCGTGCTCATCACCGCACCTGGATGCCTGGCTGAACTTCAATCTCGGCGAGATTGGAACATCGGCTGACGGAGGTGCATCGCCAAAACTGGGCAACGTTTTCGAGGACGAAATCATCAAGCAGGAGCAATCGCCCACGCAGAAATTGCCGTCGATGAACTCTACCTTTGGTACCCCCAAATGCATTCCCATGTGCGCGGGCAATTACGGGGACTACTCGAATATGTACCAGGGACCGTCATATCCTGCCGAAAATTACCAGCATAATTTGGCTCAAGCTATTGAAAAGCCAAATCGTGAACACAAGGACATCTGGACTATAGATGAGCTGGACGAATTGATGCTGGGtgagcagcaacaggagcaacatcaacaacagcaTCTGTCTTCACAAATCACACAACAACCTGATCTAGTTGATTATTATCCAGAGGATCATATCAAGGCAGAGGAATTTCGCAATCTTGACAGTGATTTTGAAGAAAACTATGACGACGAGGATGATGAGGTGTTCTCCCTTCCGGCGGAAAACGAAACTAAACCTGATTCCACCTGCTGCGACCCAGAGGCTGAAACAGAGGCTGTACCACTGATTTGCCGCTGGACTGGCTGCGACGAAGAGTTTCCCAACCAACAGACCTTTGTGGAGCACATCGAGAAGTGTCACGTGGATGTGCGAAAGGGCGAGGACTTCTCCTGCTTCTGGCTAGATTGCCCCCGTCGCTACAAGCCCTTCAATGCACGCTACAAGCTGCTCATTCACATGCGGGTCCACAGCGGAGAAAAGCCCAACAAATGTCCGTTTCCCGGCTGCAATAAAGCATTTTCGCGtttggaaaatttgaaaattcatCAACGCTCGCACACGGGAGAACGGCCTTATGGCTGCCAGTATAAAGGTTGCCTCAAAGCGTTCAGCAATAGCTCGGATCGGGCGAAACATCAAAGGACCCACTACGACACGAAACCGTATGCCTGCCAGCTACCAGGATGCACGAAGCGCTACACGGATCCCTCCAGCCTCCGTAAACATGTCAAGAACCACGCTCTACGCAACGCCAACGGACAGCTGATGCGCCGCAAATCTGCCGGAGGCTCTGGATccggcaacggcaacagctCCATCAATGGCTCCGTCTCTGGCTCGGGCTCCACATCATCTGGCAGCGGAAGGAAGTCGGCCAAAACACGCCGCCACTCGGAATCGGCGGTGGGCGGAGTGACAACGATGGCAGGTGCAAAGCCAACGAGTGTGACAGGCGACCAGCATCGGCAACAGCGCAGCAATAGTTGCAGCGAAGCCTTGCTGCGGATAGACCGCAATGATTGCAGCCGTATTGCGACGGGTGGTGTTGCAGCTAATAACAATTCAATGAACTTTAATGAGTTGTCAAATTGCATTGTCATCATTAAGCACAATCAGAACGGAGCTGCAACATCGGcaaccacagcagcagcagcagcagcaacaacgacaacaacacgGACTTATGCCACAGCAACAACGGAAACGGATGCTCTAAGCGTTTGCAGCagtaacagcaacaacagcatgGTTAACACCCACTACAATGGCCCGGGAAATATTAATCAATTAAGCGAACTCGAACAATTGCTGAAGCCGGCAGTTTCTGGGGAAACAGCTAATGGAATTAGCTTGGCCAGGAGCGGTAGCAACATCACCATTAGCAACAACCATTTGAACGAATTTGTGTCCTTCGAGTACGTGACAAAATACCTCGCCGATGCGTACGAGCCGTCAAACAAGAGTTCTGCGGATAATTATCATTTGCAGCCAGAGTTCGACAATAACTTTGATATGCTGGACTTTCAGCAATTCATATGA
Protein Sequence: MSSTLKIASQNGGMYVKTSEISGKAGPCYGGFMSPPLSANMCSAAGADRQTFRVPAKVEPGTAHNNFVSGDLQFPDFSHLCFAAETPNSVFSDCNNYAGQDQQQDSDQDDIVCAAAGNTGILPYQQGQYTQLNREDIFRFEPEDIARLTGDSADFNGMPPQTPYTPYTPYTPCSAQNTQLPVQATCAESINLDIDYFNYDEINCQSKNQSPCSSPHLDAWLNFNLGEIGTSADGGASPKLGNVFEDEIIKQEQSPTQKLPSMNSTFGTPKCIPMCAGNYGDYSNMYQGPSYPAENYQHNLAQAIEKPNREHKDIWTIDELDELMLGEQQQEQHQQQHLSSQITQQPDLVDYYPEDHIKAEEFRNLDSDFEENYDDEDDEVFSLPAENETKPDSTCCDPEAETEAVPLICRWTGCDEEFPNQQTFVEHIEKCHVDVRKGEDFSCFWLDCPRRYKPFNARYKLLIHMRVHSGEKPNKCPFPGCNKAFSRLENLKIHQRSHTGERPYGCQYKGCLKAFSNSSDRAKHQRTHYDTKPYACQLPGCTKRYTDPSSLRKHVKNHALRNANGQLMRRKSAGGSGSGNGNSSINGSVSGSGSTSSGSGRKSAKTRRHSESAVGGVTTMAGAKPTSVTGDQHRQQRSNSCSEALLRIDRNDCSRIATGGVAANNNSMNFNELSNCIVIIKHNQNGAATSATTAAAAAATTTTTRTYATATTETDALSVCSSNSNNSMVNTHYNGPGNINQLSELEQLLKPAVSGETANGISLARSGSNITISNNHLNEFVSFEYVTKYLADAYEPSNKSSADNYHLQPEFDNNFDMLDFQQFI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00539237;
90% Identity: iTF_00566366;
80% Identity: -