Basic Information

Insect: Drosophila anomalata
Gene Symbol: Znf574
Assembly: GCA_035046425.1
Location: JAWNNY010000476.1:1574354-1576566[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 2.3 1.9e+02 3.0 2.5 2 23 343 365 342 365 0.94

2 10 0.054 4.6 8.1 0.1 6 23 375 392 375 392 0.98

3 10 4.8e-06 0.00041 20.8 3.3 1 23 398 420 398 420 0.98

4 10 0.23 20 6.1 0.7 1 14 429 442 429 452 0.73

5 10 0.00049 0.042 14.5 2.6 1 23 460 483 460 483 0.97

6 10 0.14 12 6.7 0.4 3 23 491 512 489 512 0.92

7 10 0.79 67 4.4 0.2 2 23 524 546 523 546 0.90

8 10 0.00023 0.02 15.5 1.5 1 23 553 576 553 576 0.93

9 10 1.7e-06 0.00014 22.3 1.4 1 23 582 604 582 604 0.98

10 10 0.037 3.2 8.6 3.3 1 23 610 633 610 633 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	2.3	1.9e+02	3.0	2.5	2	23	343	365	342	365	0.94
2	10	0.054	4.6	8.1	0.1	6	23	375	392	375	392	0.98
3	10	4.8e-06	0.00041	20.8	3.3	1	23	398	420	398	420	0.98
4	10	0.23	20	6.1	0.7	1	14	429	442	429	452	0.73
5	10	0.00049	0.042	14.5	2.6	1	23	460	483	460	483	0.97
6	10	0.14	12	6.7	0.4	3	23	491	512	489	512	0.92
7	10	0.79	67	4.4	0.2	2	23	524	546	523	546	0.90
8	10	0.00023	0.02	15.5	1.5	1	23	553	576	553	576	0.93
9	10	1.7e-06	0.00014	22.3	1.4	1	23	582	604	582	604	0.98
10	10	0.037	3.2	8.6	3.3	1	23	610	633	610	633	0.97

Sequence Information

Coding Sequence: ATGGCAGATTCCTCGTCTTGCTGTTTACTCTGCATGTGCGAGTATCAGGAGATGATGGCCGACTACATAGATGTGCATTCCGCCAGGGGAACGCAACTGGAAATAGCCCGCATTGTGGGCCAGCACTTCCCGCTACAGATATGCCTAGCCAGTAACGAAAGGATCTGCGGACGCTGCTGGAAAACGGTCTCCGACTTCCATGCCCTCCACGAATTCGTCAGCGCTGCTCAAAACTCATTGCAGGAAACAAAGGTGCTGCTCATGGAGGATGATCCTTTAACCCAGGCCGCCCCCGTCTATACTGACGTTCCGAAATTGGCAGTCGAACAGGTAGAACAGGTGCAGGCTCCGTCAGAAGTCGCTGGACGAAGCTTCTTCTATCCGGAAGTGAAGATCGAGGAGCACGAACTGGACCACCTACCTAGGATAGAGATTCTTGAGGGCGCAAGCAGCACGCAAGGTAACCAAGATCAATTGGATGGAACGACCCGACGGCTAAGGAAACGCGTAAAAGCCGAAGAAGGATCAATTACTGAGCAAGAGAAGTATGAAGAGCCTCTAGAAAGCTTGGAGTTGGAGCCTTCGCCGCCCAAGAAAAAGCGAGGACGTCCCCGCAAGGCAGACACCGCTAGCGCTACGCTCACATCCACAGTGATTGCCATTCCGGACAAACCGAAAGAGGACACTGAAGTAACTCTCAAATCAGAGGAGATAGAGGAATTTATAGACGACGACCCAGATTTCTCTTGCAATTTGGACGATGGCCAGGCGCCAAGTGATAATTCCTCTGACGACAACTTTGGCAGTAAtgattttgatacagattcGGACTTTGAGTTGGACAGCCATGCCAAACAGGAGTTTGCGGTGCTTCCCAAGCGGACTGTGGTGCGACCCAAGAAGTACAAGAAGCGTACGAAACCGGCGGAGCCTAAGGTGCGCATGTCCCGTGAACTGTTGGAGCAGCGCAAGAAGCAGCAGGAGGAGTACGACGGAATTATTGCAAAGTTCTTTACCGACGTACTGCCGTGCTCGATCTGCAACTTGCTGGTGCACAACTTCACCGAGATGCAACGCCACCACCGACTGTCCCATCAGGTGGATCCTGGTTATATGATGTGTTGTGGCCGAAAGTTCACGCAGCGTAAAGTATTGGCCGAGCATGTCCTGGTCCACTGGAATCCGGATCACTTCAAGTGTACCGTGTGCGAGAAGTCGTTCCAGAACTCACGGCACCTAGAGTCTCACCAACAAGTCCACATGGATCCGGCCATTAAGTTGACCTTCAGTTGCGACATTTGCGAGAAAACCTTCCTCAGTAAAACGGCCATCGACTACCACAAGCTGAACAAGCATGTCCCCAAGTCGGAATTCAAATTCACGTGTTCAGAGTGCAATAAGAAATTCCTCACTGAGCGCAAGCTGAAGAACCACATGAGTTCGATGCACGACCCGGAAAGTACCATCATCTGCGACAAGTGCGGAAAACAGATGCGCACTAAGatcattttgaaaaagcacCAGGAACTGATGCATTCTGACAAACCGCGCCCGGAGCCCGAGCTGAAGCAGTGCCAGGTCTGTGGGGCCTGGCTGAAGGGCATGACAGGACTCAAGCAGCACATGAAGAGCATACACGAGGAGAGCGTCGGCGAGCATCGCTGTCCCATTTGCAGTAAGGTATCGCCGAATGCTCGGGCATTGAGGCGCCACATATACCACAACCATGAGTGCGAGCGGAAGTTCAAGTGTACCATGTGTGAGAAGGCTTTTAAGCGGCCGCAGGAACTGAAGGAACACACGTCCACTCACACCGGCGAGGTGCTGTACACCTGCCCCAACTGTCCGATGACCTTCTTCTGTAGCGCCAATATGTACAAGCATCGCCAGCGACTGCATCGCGCACAATACGAGGCGGATAAGAACCAGCCGAAGCCGCCAAACATTCTGAAGATCTCGCGCATCGCTTCATCCCAGAACAAATCCAAACAGGACATTTAG
Protein Sequence: MADSSSCCLLCMCEYQEMMADYIDVHSARGTQLEIARIVGQHFPLQICLASNERICGRCWKTVSDFHALHEFVSAAQNSLQETKVLLMEDDPLTQAAPVYTDVPKLAVEQVEQVQAPSEVAGRSFFYPEVKIEEHELDHLPRIEILEGASSTQGNQDQLDGTTRRLRKRVKAEEGSITEQEKYEEPLESLELEPSPPKKKRGRPRKADTASATLTSTVIAIPDKPKEDTEVTLKSEEIEEFIDDDPDFSCNLDDGQAPSDNSSDDNFGSNDFDTDSDFELDSHAKQEFAVLPKRTVVRPKKYKKRTKPAEPKVRMSRELLEQRKKQQEEYDGIIAKFFTDVLPCSICNLLVHNFTEMQRHHRLSHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCTVCEKSFQNSRHLESHQQVHMDPAIKLTFSCDICEKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELKQCQVCGAWLKGMTGLKQHMKSIHEESVGEHRCPICSKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQYEADKNQPKPPNILKISRIASSQNKSKQDI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00494659;
90% Identity: iTF_00615758;
80% Identity: -