Basic Information

Insect: Drosophila anomalata
Gene Symbol: PRDM5
Assembly: GCA_035046425.1
Location: JAWNNY010000147.1:1528878-1530861[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.46 40 5.1 0.2 3 23 265 286 264 286 0.92

2 10 4.9e-05 0.0042 17.7 0.1 6 23 295 312 295 312 0.99

3 10 5.5e-06 0.00047 20.6 0.4 1 23 318 341 318 341 0.98

4 10 9.5e-05 0.0081 16.7 0.4 1 23 350 372 350 372 0.97

5 10 0.013 1.1 10.0 5.5 1 23 379 402 379 402 0.97

6 10 6.5e-05 0.0055 17.3 1.9 1 23 408 430 408 430 0.96

7 10 0.28 24 5.8 0.9 2 23 439 460 438 460 0.96

8 10 2.1e-05 0.0018 18.8 2.2 2 23 466 488 465 488 0.95

9 10 1.9e-07 1.6e-05 25.2 0.7 2 23 495 516 494 516 0.97

10 10 0.00017 0.014 16.0 4.4 1 23 522 545 522 545 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.46	40	5.1	0.2	3	23	265	286	264	286	0.92
2	10	4.9e-05	0.0042	17.7	0.1	6	23	295	312	295	312	0.99
3	10	5.5e-06	0.00047	20.6	0.4	1	23	318	341	318	341	0.98
4	10	9.5e-05	0.0081	16.7	0.4	1	23	350	372	350	372	0.97
5	10	0.013	1.1	10.0	5.5	1	23	379	402	379	402	0.97
6	10	6.5e-05	0.0055	17.3	1.9	1	23	408	430	408	430	0.96
7	10	0.28	24	5.8	0.9	2	23	439	460	438	460	0.96
8	10	2.1e-05	0.0018	18.8	2.2	2	23	466	488	465	488	0.95
9	10	1.9e-07	1.6e-05	25.2	0.7	2	23	495	516	494	516	0.97
10	10	0.00017	0.014	16.0	4.4	1	23	522	545	522	545	0.96

Sequence Information

Coding Sequence: ATGATCTGCCGCCTCTGTCTGCGCAGCCTGAGTCCCGGAACAGCAGTCTTTCTCTTCGAAACGAACGAGACTCTGGCGGAGACGCGCCTGGTGAAGATTATCGCCAAGTTTCTTCAAATGGAAATACTTCCGGACGATGGAATCTCGACCAGCGTGTGCACAGAGTGCTGCGAGCACCTCGAGGACTTTCACAGCTTCTGGCAGCTGGTGGAGCAGAAGCAGAGCACCATCATGAACGAGGAGTTTATATCCGTGGACGTGGACTGCGGCGACCTAAAGTGGACAGGAGGCGTGGACGTGAATCTAGACGAGCTGGCTCTGCCTGCAGGAGACGTCGATGAGAAGCCTCTGGACATGCACAACCTCAGTTTGCTGGGCAGCGTTCTCGACGTGAATGTCGACAGTGTGGAGGTAACCGCCGCCAAGAAGCAGTcccaggaggaggagaagcccCTGGTGCAGAAAAGTGATAATAGTGATTCGGAGCCCGAGCCCACATCATTTCCCGCCGACGATTCATCATCCGATGaCGAGCCACTGGTCCGGCTGAAGGCAAAAATGAAGCCGAAGCGCAAGGTACGATCCAAGGTCAAGCGCTCGATTTCACTGCAGCAGGAGCTTAAAGATCTACTAACCGATGGCAGCAAGCGGCGCACGAAGCGGTCTACCGAGCCCACCGAAATGCAGGAGACGGAGCTACAGGCGGTGCTCGAACGCAAACCGAAGGGCTGCTCCCGCGCCCAGCTGGCCAAGCGCTACGAGGAGGCCATCGCCAGCTACATGAGCGCCAATTGTGATCTGTGCGAATTTAGCGCCCCGTACCTGACCGACCTGAAACGCCATTTCCAGGAGGTGCACCAGCGCGAATACTACATCAAGTGCTGCGGCAAGGTCTTCGCACGAGCGTCCAAGCTAATGGATCACATCCGGAAGCATGTCAATCCCAATCTGTTCACATGCACCATCTGCCAGAAATCGCTGAACTCACAGGACTACCTTGCCACCCACATGGAGACGGTCCACAACAAGGTCGCCCAGGTTCTGAAGTTCCCCTGCGCCAAGTGCGATCGCACTTTCAGCAGCGAGCGCCGACTGGCCAATCACTTGGCCAAGCACGACTCTGACCAGTTGGAACACACCTGCGAAATCTGCTGCAAGAGCTTTGCCAATGTACACCGTCTGCGGCGGCACATTCAATCTATCCACGAAGATCTGCATCGCCACGTCTGCGACATTTGCGGAAAGAAGTTCAAGTTCAAGCCCTCCTTTGACCGCCACCTGCTGGAGCACCAGGGCGTGGTGGCGCCCGCGATGGAGTGCTCGGTTTGCGGGGTATGGCTAAAGAACGAGCACAGCCTGCGTCTGCATCGATTCACCCACGACAGCACGGACACGGTGTGTCCGCACTGCGGCAAAACCTGCTCATCCCGCACAGCGCTGCGTGGTCACATCAAGTACGCCCACAAGCTGACGACGAACCTGCAGTGCACCTACTGCGAGAAGACCTTCAAGCAGCAGCGCAACCTAGAAGAGCACATGGCCATCCACACGGGCCTCCAGCTCTACAACTGCCCGCACTGTCCCAAGGAGTGTCGATCCCGTTCCAATATGTATGTACACATAAAGCAGCGGCACGCGGACGAGTGGCTGCGCGCCAAGATGGCCCGCTCCCACAATCCGCAATTCAAGCCGGGACCGGAGGCAACGGCCGTGCAATCCTGA
Protein Sequence: MICRLCLRSLSPGTAVFLFETNETLAETRLVKIIAKFLQMEILPDDGISTSVCTECCEHLEDFHSFWQLVEQKQSTIMNEEFISVDVDCGDLKWTGGVDVNLDELALPAGDVDEKPLDMHNLSLLGSVLDVNVDSVEVTAAKKQSQEEEKPLVQKSDNSDSEPEPTSFPADDSSSDDEPLVRLKAKMKPKRKVRSKVKRSISLQQELKDLLTDGSKRRTKRSTEPTEMQETELQAVLERKPKGCSRAQLAKRYEEAIASYMSANCDLCEFSAPYLTDLKRHFQEVHQREYYIKCCGKVFARASKLMDHIRKHVNPNLFTCTICQKSLNSQDYLATHMETVHNKVAQVLKFPCAKCDRTFSSERRLANHLAKHDSDQLEHTCEICCKSFANVHRLRRHIQSIHEDLHRHVCDICGKKFKFKPSFDRHLLEHQGVVAPAMECSVCGVWLKNEHSLRLHRFTHDSTDTVCPHCGKTCSSRTALRGHIKYAHKLTTNLQCTYCEKTFKQQRNLEEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLRAKMARSHNPQFKPGPEATAVQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615740;
90% Identity: iTF_00481701;
80% Identity: iTF_00476095;