Dano002574.1
Basic Information
- Insect
- Drosophila anomalata
- Gene Symbol
- -
- Assembly
- GCA_035046425.1
- Location
- JAWNNY010000448.1:1131674-1134802[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 9e-05 0.0077 16.8 2.6 1 23 174 197 174 197 0.96 2 14 0.0031 0.26 12.0 1.1 1 23 214 237 214 237 0.95 3 14 0.0011 0.092 13.4 2.8 1 23 310 333 310 333 0.96 4 14 0.0021 0.18 12.5 0.7 2 23 390 411 389 411 0.95 5 14 0.018 1.5 9.6 0.6 1 23 555 577 555 577 0.94 6 14 0.001 0.089 13.5 0.6 1 23 584 607 584 607 0.96 7 14 8e-05 0.0069 17.0 3.3 1 23 615 637 615 637 0.98 8 14 0.0059 0.51 11.1 0.1 2 22 664 684 663 687 0.90 9 14 0.00085 0.072 13.8 1.3 1 23 722 745 722 745 0.96 10 14 0.004 0.34 11.6 0.2 1 23 782 805 782 805 0.96 11 14 3.9e-05 0.0034 17.9 0.4 1 23 827 850 827 850 0.96 12 14 0.0047 0.4 11.4 0.2 1 23 860 882 860 882 0.96 13 14 4.8e-05 0.0041 17.7 2.1 1 23 888 910 888 910 0.99 14 14 1.2e-05 0.001 19.6 1.2 1 23 916 938 916 938 0.97
Sequence Information
- Coding Sequence
- ATGACCAGGACATGCAGGATCTGTGGCGGAGTCGATGGGCGGTACTGGGTCGAAACGCCCGTGGAAAAGTGCGCCGGGAAGACTTTCGTCCAGTTAATGGCAGAACTGACCAAAATTGAGGTGTCTGCACTTTTGAGCGAGAAGTTTCCGCAGTGGCTCTGTGCTGGGTGCGCACATAAGCTTGAAATGGCCTATGAATTAGTGATGCAAGCCAAAGAGACGCACAATCTGTGGATGCAAAAGTTAGGAGAGGAAACAAAGGATCGGGACGTGGAGTCGCAAGGGATGGAAGCATTGGAGTGCCTCAAGGAGACGCCTATCCACCTGTTTGATATCGAAGGAGTAACGATTAAAACAGAGGAACTAGACCAAACGCCTTCAGTCGCGAAAAAAGACCCTCTCATCCGTCCGCGCATTGTGAAGCGGAGTATTACACATTACAGTGACGCTGACGACGACCAGGACGATGTACCCCTTCGCCAGACCCGCAAGCACTTGCCGTTTTCTGTTCAAAAGCTGCATATCTGCAGCATCTGCAACAAGGCATTCCGATATGTAACAAATCTGTATCGTCACAGGCAGAGGGATCATGGTGCGCCCGGAAAACCAGGCACTGACCTGGACGAGGATGAAAACTATTATAAGTGTGATCAGTGTGACAACTCATTTAAGTACGTTATGGATTTGGTGAAGCACAACAAAAATGAACACGATGCTAGTCTGCTGCCCTCCAAAATGTACCTccaaaaatgcaaaacgtCTCGTCGAACAACACCAACGCAGGAGGAAGTAACCCGTTCAAGTCCTGCATCGACTGCAGCAACTTCGACGCAGCGAAAAACATGCAAGAGTGATACATTAGTGCACAGCTTCATCAAGACCGTAGTTCTCTCAGATGAAGATGAAAGCAGCAGCTCAGAGAACTACTATAAGTGCGAGGACTGCACCAAGTCGTACAAATACGTCATAAGCCTAATCAAGCACAAGCATAGCGAGCACTCTGGCGAAAACAGGCAGTTAGGAAGACAGGAGGTGGAGGAAGATCAGCGCATTGGTGCTTCTACGTCAACTGTTTCTGCAGCTGTGCTGCCGAAACCATCGAGGATCAACCGGCGCGTCAATGGATTTGATCTTCATCGATGCGAACCCAATGGGGCTAAAGAAATAAAGTGCATGATTTGCTTGAAACGGTTTACAAAGCTTCGCCAGTTAAGAGATCACCTAGAAGCGCATCCGAccgatttcgatttcgaaGCACATGGGGAACCAATCGAAAGAATTGCCGAGGGGTTTTTCAAGACCGCTGTAGAGTCGACGTCGGAGGGCTTAAAGCGTCGGATATTAAGAGATCTGAGACTGGGCGTTTATGGGCGCTATTATTCCATCACAAATGAAGCTCGTTACGAAATGAGTCTGGACAGTTCGGATACAGACagtgatggtgatggtgagGATGTTGTGGTGAGACGTAGCTATGTTTGCGATCTGTGTGATGATCCCGATGCTAGGTGGCCGCGAAAGTATCAAATCCACAAGCATCATCTTCAGGAGCACAACTGGCTAGACGCTCCCCACGTCTGTCTGCGTTGCGATTCCAGGTTCTTGAATGCCGATCTTCTGGACCACCATACCAGCCAACTGTGTCAAAATACCCTTAAGCGTTTCATGTGTGACAAGTGTCCGCAGCGCTTTTTTTGGCGCAGAAATCTTCGCGCCCATCTTGTGGAGCATAAGAGCAAGCAAGACAGCTATCCTTGCGATCAGTGCTCCCGCAGCTATCAGGACAAGAGCGCCGTAACCAAGCACAAGTTAATGATGCACCGGGACAGTAGCACCCAACTATTTCCCTGCCGGTGGTGCACCCGCACCTTTTACCGCCCCTCCTTGTTGCACAAGCACGTCAAGCGCCATGGATTTAGTGGCGATGACCTGCCGTTGGCAGAAACTCTCTTGGCTGATGCCGCAAAGGCAACCAGGCCGAAAACCATCCAGTGCAAGCTGTGCGAAATCCAGTTTATCAGCGTGGTGGATCTACGCCGGCACATATCCATGCAGGGCCACAGTGATCAGCCATCGGCCTACATGATAAGCACGGAAGCTGGCTTCGAAATGCTAATAGACGACACCGATGACAGTGATGAGGAGAGCTCCTCCGGCAGGTGCTACTCCTGCGATATGTGCCAGCTTAGTTTCCGGCGCAGGAAAGATATAAACGAACATCAGTACTCCCTGCACAGCTTCGATAAGCTGCCCTTTGCCTGCGAACACTGCATTTTTAAAACGGTGGATAAGGATATCCTGGAGCAGCATTTGATCACTCAGTGTCGAAAcaatgaaaagaaatttatcTGCCCGCGCTGCGGATACAAATTTATGTGGGAAGAGAATCTGACCCAGCACCTAGCCACTCAGCACCAGACCAAAAATCAGAACATTCCGGAACAACAGACACCTCTGCGACGCAAGAGAAGATTTCGTTATCAGTGCCCTCATTGTTGGCGATCCTTTGTGGCTCAGCCTAGCTTGGACAAACACATTCGGGACATGCATGTGGCCAAAAGGAACCTCGGAAAGAAGTATCTGTGCTCCCTGTGCGGCTTAGAAGCGCAAACTCCCAACAAACTTAACATCCATATGCGACGGCACATGGGTGAGAAACCATTTAAGTGCGATCTCTGTGACATGCGCTTTACGGTTTTCTATGAGCTGAAGGTCCACCGGCGAAAGCACACGGGCGAAAGACCCTACCAGTGCACCTTCTGCTCTAAGGAGTTCGCCCGCCCAGATAAGTTGCGGCGACATGTTTTTATCCACAATGTAAAACCGCAGTGA
- Protein Sequence
- MTRTCRICGGVDGRYWVETPVEKCAGKTFVQLMAELTKIEVSALLSEKFPQWLCAGCAHKLEMAYELVMQAKETHNLWMQKLGEETKDRDVESQGMEALECLKETPIHLFDIEGVTIKTEELDQTPSVAKKDPLIRPRIVKRSITHYSDADDDQDDVPLRQTRKHLPFSVQKLHICSICNKAFRYVTNLYRHRQRDHGAPGKPGTDLDEDENYYKCDQCDNSFKYVMDLVKHNKNEHDASLLPSKMYLQKCKTSRRTTPTQEEVTRSSPASTAATSTQRKTCKSDTLVHSFIKTVVLSDEDESSSSENYYKCEDCTKSYKYVISLIKHKHSEHSGENRQLGRQEVEEDQRIGASTSTVSAAVLPKPSRINRRVNGFDLHRCEPNGAKEIKCMICLKRFTKLRQLRDHLEAHPTDFDFEAHGEPIERIAEGFFKTAVESTSEGLKRRILRDLRLGVYGRYYSITNEARYEMSLDSSDTDSDGDGEDVVVRRSYVCDLCDDPDARWPRKYQIHKHHLQEHNWLDAPHVCLRCDSRFLNADLLDHHTSQLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKSKQDSYPCDQCSRSYQDKSAVTKHKLMMHRDSSTQLFPCRWCTRTFYRPSLLHKHVKRHGFSGDDLPLAETLLADAAKATRPKTIQCKLCEIQFISVVDLRRHISMQGHSDQPSAYMISTEAGFEMLIDDTDDSDEESSSGRCYSCDMCQLSFRRRKDINEHQYSLHSFDKLPFACEHCIFKTVDKDILEQHLITQCRNNEKKFICPRCGYKFMWEENLTQHLATQHQTKNQNIPEQQTPLRRKRRFRYQCPHCWRSFVAQPSLDKHIRDMHVAKRNLGKKYLCSLCGLEAQTPNKLNIHMRRHMGEKPFKCDLCDMRFTVFYELKVHRRKHTGERPYQCTFCSKEFARPDKLRRHVFIHNVKPQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00550395;
- 90% Identity
- iTF_00550395;
- 80% Identity
- -