Basic Information

Insect: Drosophila anomalata
Gene Symbol: ham
Assembly: GCA_035046425.1
Location: JAWNNY010001937.1:2940473-2957932[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.05 4.3 8.2 0.0 2 21 321 340 320 343 0.87

2 9 0.0063 0.54 11.0 1.3 1 23 350 373 350 373 0.93

3 9 1.5e-07 1.3e-05 25.6 1.8 1 23 379 402 379 402 0.96

4 9 9.1e-07 7.8e-05 23.1 1.6 1 23 408 430 408 430 0.97

5 9 2.4e-05 0.002 18.6 3.3 1 23 436 458 436 458 0.97

6 9 0.00056 0.048 14.3 1.7 2 21 466 485 465 486 0.94

7 9 5.4e-09 4.7e-07 30.1 1.3 1 23 923 945 923 945 0.99

8 9 3.9e-07 3.3e-05 24.3 0.5 1 23 951 974 951 974 0.97

9 9 6.2e-06 0.00053 20.5 1.3 1 23 980 1002 980 1002 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.05	4.3	8.2	0.0	2	21	321	340	320	343	0.87
2	9	0.0063	0.54	11.0	1.3	1	23	350	373	350	373	0.93
3	9	1.5e-07	1.3e-05	25.6	1.8	1	23	379	402	379	402	0.96
4	9	9.1e-07	7.8e-05	23.1	1.6	1	23	408	430	408	430	0.97
5	9	2.4e-05	0.002	18.6	3.3	1	23	436	458	436	458	0.97
6	9	0.00056	0.048	14.3	1.7	2	21	466	485	465	486	0.94
7	9	5.4e-09	4.7e-07	30.1	1.3	1	23	923	945	923	945	0.99
8	9	3.9e-07	3.3e-05	24.3	0.5	1	23	951	974	951	974	0.97
9	9	6.2e-06	0.00053	20.5	1.3	1	23	980	1002	980	1002	0.98

Sequence Information

Coding Sequence: ATGCTGTTCGATCGATACGTCATATCAGCAGGCTCCAACGGCAGTGACGACTTCGACCCAAGTGCGAGTGTTGTGCGTCATCACCACCatctccaccaccaccacctggaTCTCAGTGGGAGGAGTCAGGGATTCCCGCCGCGGCCCGATCAGATCGAGGACCCCTTTGCCAGTCGCCATTCGCAGGCAGAAGGGTCTCCGCCAAGCAATCAGGACCATCCTCTTCTGCAGAACCACTCCAATCATCTCCAGCTACAGCCCCCGCCTCCCACGTTGCCGGTGCCAGTGCCAGGAATAGAatctgccgccgccgctgcaggatCTGCCGCCAGCATGGAGAACTTGCAGCTCTTGCAGGAGTGGGCGCGGAGGCGCGAACCCGTCTGTGATCTGGACATCCGCGAGAGCGGCGTCTACGCAAAGACCCCACTCCCAAGGGGCACCCGGTACGGGCCCTTTCCGGTGAACCTCTGCCATCAGCCGAACGATATGCAGCTGGCGTGGAAGGCCCAGGCTGGCCACTATAACGGATGGCTCGAGCCCACATCCGAGGTTTCGGCGTGGCTGAAAAAGATCCGCGTCGTGCAGGACGAGGGCATTTCGAAGGCCAATCTGCAGAGCTACATCGATCACGGCTGTctGTGGTACGAGACGAATTGCCATGTAAGTGCTGGCGTCGAGATGGTCGTGGACGGCAGGCCCCACAGTCCGGTGCAGATTAACGAGAGCTTCGTTGCCGGAGGGGGAGTCCTGGCggcagccgccgcagcagcagcagcggcagtggcagccgcCTCATCCTCGGGAGTGAACAGTGGAGGCGGTGGCAGCTCCCTGGCGGGCGATGATCGCAGTGACCGTGATAATGGCTCTTTGTACAGCGGTGACGAATTCCCCAAAGATAAGAAAATCATCCAGGGTGATATCGACTTCACAGACGACGAACACGGATTCGATATACGCTGCGAGGTCTGTGATAAAGTCTATCCGGACTTAGAACGCTTGGACGATCATCTGGTGGGCGTGCATCACTTCAAGCAGGACGACTTCCCCTGCAAGCTCTGTTCGCAGCGATTCTGCTATCGTCCTCTGCTGATCAAACACGAAGCCATCTCCCACAACAATATACGGAAGTATTCCTGTGAGAATTGCACCAAGGTATTTTGTGACCCCTCGAATTTACAGCGGCATATTCGCGCCTACCACGTCGGAGCTCGCTGTCATCCGTGTCCGGAGTGCGGGAAAACGTTCGGAACTTCCTCGGGCTTGAAGCAACACCAGCACATCCACAGCTCGGTAAAGCCCTTCGCCTGCGAGGTCTGCTCCAAGGCGTACACGCAGTTCTCGAACCTGTGCCGGCACAAGCGGATGCACGCCACCTGCCGGATGCAGATAAAGTGCGACAAGTGCAGCCAGAGCTTCAGCACCCTCACGTCCCTGACGAAGCACAAGAAGTTCTGTGATTCCACCGGATCGTACCGCCAGCCGCTCAACCGCCATCATCCGCATCAGCAGCCACTGCCGCACCACCAGCACCCGCACACCCATCCACtggcagccacagccacatccTCAGGCACAGCCGGAGAGCCCTCAGGACCGGGATCAGGTTCGGTGCCAggatcatcatcatcagcagcagctgccgccgtAGCCGCCATGTCGACGCCTCCGAATCCATTCCTCATGTTCCGCAACGGAGCCCCCTTCTTTCCGGGCTTTCCGCCATACGGCCTGCCCGGAATCTTCCCGCAAAGTCCCCTGCGGGCGGCCAACTTTCCGCTGTTCTTTCCAAAACCGCCTCTGGATATGAATATGCCAACATGCCAACCGTTCCGCCAACAGCTGCCCTTCGGGTTACCCGGCATGGAAATGCACCAAGGTGATCCCCAGACGGATATCCAGCTGAAGAACGAAAGCATGGCCGAGAAAAAGCTCAAAGAAGAGCCGATGGTGCATGTGTCCGAGGGCGAAGAGGATGAAGAGGGATCCTTGGATCTCAAGAGGGAAGTGGGGCATGTGAAGGACGAGGCAAAGACCGAGAAGCAGCGGGAGGTGAAAACAGAGCCGGAGAGATCAGACAGCCCGGATCAGCAGCTGGGCGAGGATGACAGGAAATCCATCGACATTGTGAGCACACCGCCTCCCACAGATCCCACCTCCGGAGAAGACCTGGACAAGCCCGCTGCGGATACTCCTTTGGACCTGTCTGTCTGCCGCAAGCGCTATGCTGGCTACTACCCGGAGATCCTGCAACCCGAAAACCGCCTCTTGTCCTCCAACCTGATGCGGTTCCTGCCCAGGACCGAAGAAGACGACACCGAAGGAGAGGAGCCGCCAATGAAGATGCGAAAGGCGCACAGCTCGGGAGAGTCCTCCACGTCGCAGAAGTCCTACAAGGGCAGCAGCCCCACTCCCACCGCTTCGCCAGGACTCACGCCCTCACCCTCGCCGCCCACGAGTGCCGGCGGCGAGCTGAGCAGCATGTCCGAGGGGGCAGTaacagcggcagcggcggctgcggctgcggcagTGGCGGCCGCTGGAGCTGCCGAGGCCGCTCTGGTGGCCCGCTACCAGAACAACACTGCTCCCCAGATACACCCCCTGATGCTGGAGGAGATCTACCGCAACCGGTATTCTTTTTTATGCCCAACGGGCGGACGGCCCGGCATTGAGGCTCTGCTGCAAAGCGCAGCTTCAAAGAGGCCGCTTCCGCCCGTGAAATTCGCTACGGGCAACCCAGCACTCAAGACAAAGGACCGGTATACGTGCAAGTTCTGCGGCAAAGTGTTTCCCCGATCGGCCAATCTGACGCGCCATCTGAGGACCCACACTGGGGAGCAGCCGTATCCGTGCAAGTACTGCGACCGGGCGTTCAGCATCTCCTCGAACCTGCAGCGCCACGTGCGGAACATCCACAACAAGGAACGCCCCTTCCGGTGTGAGCTCTGCGACAGATCCTTCGGCCAGCAGACGAATCTCGATCGGCACGTGAAGAAGCACGAGGCGGAAGGCAACAACTTCCGCGACTCGCCCAGCTCCGGCGGGATGGCGGACCGCGAGGAGTACTTCGAGGAGATCCGGACCTTCATGAACCACGTCTACACCCCTAATAGCCTGATTGGAGCGGAGGGGGACACCGAGGAGTATCCCAACAGTGATGACCAGTCTGTGAGCCTCGAAAAGGATACCAGCATCAAtctgaacaacaacaacaatagcagtAACAGCAGCAAAAGCAATCCAAAAGCTATAACAATAAGCTCTTAA
Protein Sequence: MLFDRYVISAGSNGSDDFDPSASVVRHHHHLHHHHLDLSGRSQGFPPRPDQIEDPFASRHSQAEGSPPSNQDHPLLQNHSNHLQLQPPPPTLPVPVPGIESAAAAAGSAASMENLQLLQEWARRREPVCDLDIRESGVYAKTPLPRGTRYGPFPVNLCHQPNDMQLAWKAQAGHYNGWLEPTSEVSAWLKKIRVVQDEGISKANLQSYIDHGCLWYETNCHVSAGVEMVVDGRPHSPVQINESFVAGGGVLAAAAAAAAAAVAAASSSGVNSGGGGSSLAGDDRSDRDNGSLYSGDEFPKDKKIIQGDIDFTDDEHGFDIRCEVCDKVYPDLERLDDHLVGVHHFKQDDFPCKLCSQRFCYRPLLIKHEAISHNNIRKYSCENCTKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCSKAYTQFSNLCRHKRMHATCRMQIKCDKCSQSFSTLTSLTKHKKFCDSTGSYRQPLNRHHPHQQPLPHHQHPHTHPLAATATSSGTAGEPSGPGSGSVPGSSSSAAAAAVAAMSTPPNPFLMFRNGAPFFPGFPPYGLPGIFPQSPLRAANFPLFFPKPPLDMNMPTCQPFRQQLPFGLPGMEMHQGDPQTDIQLKNESMAEKKLKEEPMVHVSEGEEDEEGSLDLKREVGHVKDEAKTEKQREVKTEPERSDSPDQQLGEDDRKSIDIVSTPPPTDPTSGEDLDKPAADTPLDLSVCRKRYAGYYPEILQPENRLLSSNLMRFLPRTEEDDTEGEEPPMKMRKAHSSGESSTSQKSYKGSSPTPTASPGLTPSPSPPTSAGGELSSMSEGAVTAAAAAAAAAVAAAGAAEAALVARYQNNTAPQIHPLMLEEIYRNRYSFLCPTGGRPGIEALLQSAASKRPLPPVKFATGNPALKTKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYPCKYCDRAFSISSNLQRHVRNIHNKERPFRCELCDRSFGQQTNLDRHVKKHEAEGNNFRDSPSSGGMADREEYFEEIRTFMNHVYTPNSLIGAEGDTEEYPNSDDQSVSLEKDTSINLNNNNNSSNSSKSNPKAITISS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00566227;
90% Identity: iTF_00476070;
80% Identity: -