Basic Information

Insect: Drosophila anceps
Gene Symbol: L
Assembly: GCA_035045945.1
Location: JAWNON010000073.1:8221198-8231844[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1e-05 0.00072 19.9 2.9 1 23 165 187 165 187 0.98

2 17 0.35 25 5.6 6.2 1 23 193 215 193 215 0.97

3 17 1.7e-07 1.2e-05 25.5 3.2 1 23 221 243 221 243 0.99

4 17 1.3e-05 0.00088 19.6 0.4 1 23 249 271 249 271 0.99

5 17 0.014 0.98 10.0 0.2 2 23 350 374 349 374 0.93

6 17 0.00031 0.022 15.2 0.2 2 23 404 426 403 426 0.96

7 17 0.062 4.4 8.0 0.7 1 23 491 513 491 513 0.97

8 17 0.073 5.2 7.8 0.3 2 23 521 542 520 542 0.91

9 17 0.03 2.1 9.0 1.7 3 23 553 575 550 575 0.86

10 17 3.4 2.4e+02 2.5 1.0 2 23 611 633 610 633 0.95

11 17 0.0026 0.18 12.4 1.1 1 23 676 699 676 699 0.97

12 17 0.0065 0.46 11.1 1.6 2 23 871 893 870 893 0.96

13 17 0.12 8.1 7.1 0.1 1 23 899 921 899 921 0.92

14 17 0.56 39 5.0 0.4 2 23 929 950 928 950 0.93

15 17 0.31 22 5.8 1.3 1 23 1055 1077 1055 1077 0.94

16 17 0.028 2 9.1 0.0 1 23 1087 1109 1087 1109 0.96

17 17 0.00022 0.016 15.7 1.2 1 23 1114 1136 1114 1136 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1e-05	0.00072	19.9	2.9	1	23	165	187	165	187	0.98
2	17	0.35	25	5.6	6.2	1	23	193	215	193	215	0.97
3	17	1.7e-07	1.2e-05	25.5	3.2	1	23	221	243	221	243	0.99
4	17	1.3e-05	0.00088	19.6	0.4	1	23	249	271	249	271	0.99
5	17	0.014	0.98	10.0	0.2	2	23	350	374	349	374	0.93
6	17	0.00031	0.022	15.2	0.2	2	23	404	426	403	426	0.96
7	17	0.062	4.4	8.0	0.7	1	23	491	513	491	513	0.97
8	17	0.073	5.2	7.8	0.3	2	23	521	542	520	542	0.91
9	17	0.03	2.1	9.0	1.7	3	23	553	575	550	575	0.86
10	17	3.4	2.4e+02	2.5	1.0	2	23	611	633	610	633	0.95
11	17	0.0026	0.18	12.4	1.1	1	23	676	699	676	699	0.97
12	17	0.0065	0.46	11.1	1.6	2	23	871	893	870	893	0.96
13	17	0.12	8.1	7.1	0.1	1	23	899	921	899	921	0.92
14	17	0.56	39	5.0	0.4	2	23	929	950	928	950	0.93
15	17	0.31	22	5.8	1.3	1	23	1055	1077	1055	1077	0.94
16	17	0.028	2	9.1	0.0	1	23	1087	1109	1087	1109	0.96
17	17	0.00022	0.016	15.7	1.2	1	23	1114	1136	1114	1136	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGTTGTATCGCGGTCCCAGTTCGCGTTTAgagaatttaattgaaaagatTCAAGCGACCAAGGAGATAACTAACCACGATATGTACAGCACGCACACTTCATCGAGCTACTCGCCCAGCATCTCCGATGGCACTTTGACGCCCAAttcacagctgcagcagccacagcagcagcagcagcagcagcagcaacagtcccAGTCCGGCGAGGAGGCGGGCGAGGAGGGCAAGGCGAATGGTGATGCTGTGCAGCAAACGGAACTCGAGCAGGAGTTGAGCAAGCCGAAGCGACCGGCACATTtgcaccatcatcatcatcatcattatcaccATCAGCAGGCGCTGAAAATAGCGAACAAGCTGCGCAAAATCAATAAGGATGCAAAACTGGCTGCAGGACAAGGACAAGGACATGGCACAGCCGCCAAGTTTGATAAGTTGACAGGGGAGGGGATTAAAAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGCTACTTGAAGCATCACGTGCAGAGCCACGCCGAGCATTTGCCTTTCAAGTGCGAATACTGCGCGAAGCTCTTCAAGCACAAGCGCTCGCGAGATCGTCATAAGAAGCTGCATACAAATGAGAGGAACTACAAGTGTCCGCATTGCGAGGCTGCTTTCTCCAGAAGCGATCACTTGAAGATTCACATGAAGACGCACGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAATCGCGGCTACAACACGGCCGCCGCCCTCACCTCCCACATGCAGAAGCACAAGAAGAATGCCGCAATTCTGGCCGCTGGCGGCAATCCCAACGCACTCAACTATAGTCCACGCTCCACGGGCTCCGCTTCCATATCGAGCAATGGCAGCTTGCATAAGCGGCGCTATGCCTTGGCTCTGGCCTCCGACAGTAGTCCTAGTCGCTTGGAGTTTCCCAAGCGGGCGCGTGGCCAGTTAACGACCACGCCCACGGCCACAACgttagccacgcccacgccgctGCTGCGCTGCAGCTACTGTCCCAAGGCCACGGAATTTAGCAGTCTCGAGCAGCTAAATGCGCATCTGCAGAGCAcacacgagcagcagcagcaacagcaacagcaacagcaacaacagcagcagcagccaaaggaTGCGGATGGCCAGACAAATGGCTTCCAGTTGAGCTGCGAGTATTGCACGATGAAATTTGTGAATATCGCTGCGCTGTTCCAGCACATGAGAGTGACGCACTTGGATCGTCTCAGCAGTCCCAATTCCTATTACGAGCACTTCAATCGGCTCGGCTCACCGCAGGCGAAGATCAAATCGGATCTGGCGACGTCGGAGAAGCCCGAACAGGAGCTGCCCACGGACttgagcagcaacaagcgACGTCCGCTAACATCGCCCacacagccgccgccgccaccgccgccgggCATCTTCTTTTGCAATCAGTGCAATGCCGGCCTGCCGGACTTCGAGAGCTTTCGCAATCATCTGAAGAGTCATATAGCCGAGGGCATGCAGCTGATCTGTCCGCATTGTGGCTTGAGTTTGCCCGAGCAGTGCGAATACGAACGTCACGTCGTCGCTCACTTCCTGATCAGCAGCTCCGAGTTCAATTGCTGCAGCACCAGCTGTGGCAAGTCGTATGCCAAGGCTGAGGAGCTGCATCAGCATCTGCTGGCCGAGCACGTGCAGACCATGCTCAAGTGTGTCCTGTGCTCCGAGCTGTGCGAGAATCGCATGTCGATGCAGCTGCACCTGGCCTGTGCGCACAGCCAGGAATCGAAGCTGCTGAGATGCAGCGCCTGCCTGGAGCTGTTTCGCAACGATGCCGACTTCCATGTGCACGTAAAGACACGCCATCAGCTGGGCAACCAGGGCCTGGGCAATCCACCAGCTCCGGCCAATCCACTGCAGTGCATGTTCTGTCGCGCCGTCTGCTCGTCGGAGCTGGaaatgcatttccatttggcGGCGCATGCGCGGCAGTTCCGTTGTCCGAGCTGCCCGGAAACGTTTCACGTGGAGTTCCTGCTGGACAGGCATATGCAGAGCCAGCATGGCGGCATCAAGGATAAGGAGTCGCCTGTGGCTGGCGGCATGGGCAGTTTGTATGTGAATGCGTTGCTGCCGCctttggctgcggctgctgcagccgctgccgcagcaaccaatgccaatgccaacaacaacaacaacaacaatagcaacctGCATATAGACTACAATGTCGCCTTCAAGGGTCTGTTTGGTGGCAACAATCCGCCAAGCAAGTTCTACAACAGTCCACTGCAAGTGGACACCAAACAGAGTCCACATCCAGCCCTCATGTACGGCCTGAGCCAGCGCTACTTGATGGAGATGTACGCCGCGAAGGCCAATTCGCCAGCCAATGCCAGTGCCGCTGAGCTGGCCACGCCGCAGCCCGTTCAATCCGCGACAGCGGccagtgccagcagcagcagcaacaacagctacagctgtggCATGTGCGAGCGTCAGGATTTGCGCAGCGAGGCTGAGCTGCATTCGCATCGGAAGCTCGCGCACAATCTGAAGACGGGCGTCAGTCTGCGGTGCGCCTATTGCTCGGGCAACTATAAGAGTCGTgcggagctggagcagcacaTGAAGAGCTGTCACAATTCCAGCGGCAAGCACAAGTGTCTCATCTGTGACGAGATCTTTCCCTCGCCGGCGATACTCGCCGAGCACAAGCTGCAGCACTCCAAGGTTGGGCAGTCCGGCAAGTGTGCCCATTGCGGCCAACAGCTGGAGCATGTGGCCGCCTTTCGTGCCCATCTGGGCGAGCATGGCAACGATGGCAATCTGCCCATGGCCTGTATTTGTTGTCGCCAAACACTGCACTCGGAATTCGAGCTGAGCTTACATGCCAAATTCCATACCAAATCGCCCAGCTGCAATAGCCTGCAGGAGCCCGTCTGTGCCCTGTGCCTGGAGCCGCTGCCCGGCGCTGGCGAGACCGCCAAGCTGTGCGACAAATGTTGCCGCAAGCACAATCTGAATGGCAAGCGCAAGGAGCaagtgcagccagcagcaatagctgcgcccgctgcggctgccgctgctgttgcagttgcagtggcAGCTGGCGCCTATCTGGAGCATCGTTGTAATCTGTGCAAAATGATCTTGCCGCATGCCCAGAAGCTGCAGGAACATCTCGTCGAGCACACCTTTGCCGGCACCGAGCAGCGCGGCTACAATTGCTACATCTGCTCCGCTGTGTTCACGGCACCCGGCGGCCTGCTCGTCCACATAGCGGAGCATGGCACGCGTCCCTATGACTGCAATTTGTGCCCGGAGAAATTCTACTTTCGTGCCGAGCTGGAGCATCATCAGCGAGCGCACGAGCTGCGCCCGCAGCCGGCAGCAATTGCAGCCGCAGCACGTCCCAAACAGGAGACGCATAGCTCGACGGCCAGCTCCCCGCTGACGCTCAGTCCCAGCCATGTCAAGCAGGAGCTCTACGAATCGGAGCCAGCAAATTCACCGAACGCCGCCGAGTTGCccgtgctgcagcagcagcagcagcagcaggaggaggaggaataCATCGAAGTGGAGCAAGTGCCGCAGGAGACGCTGCGCACCGGCGAACTGCTAAGCACCGAGCgttccagcagcagcgcctaA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNHDMYSTHTSSSYSPSISDGTLTPNSQLQQPQQQQQQQQQQSQSGEEAGEEGKANGDAVQQTELEQELSKPKRPAHLHHHHHHHYHHQQALKIANKLRKINKDAKLAAGQGQGHGTAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGQLTTTPTATTLATPTPLLRCSYCPKATEFSSLEQLNAHLQSTHEQQQQQQQQQQQQQQQPKDADGQTNGFQLSCEYCTMKFVNIAALFQHMRVTHLDRLSSPNSYYEHFNRLGSPQAKIKSDLATSEKPEQELPTDLSSNKRRPLTSPTQPPPPPPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLICPHCGLSLPEQCEYERHVVAHFLISSSEFNCCSTSCGKSYAKAEELHQHLLAEHVQTMLKCVLCSELCENRMSMQLHLACAHSQESKLLRCSACLELFRNDADFHVHVKTRHQLGNQGLGNPPAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGIKDKESPVAGGMGSLYVNALLPPLAAAAAAAAAATNANANNNNNNNSNLHIDYNVAFKGLFGGNNPPSKFYNSPLQVDTKQSPHPALMYGLSQRYLMEMYAAKANSPANASAAELATPQPVQSATAASASSSSNNSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCNSLQEPVCALCLEPLPGAGETAKLCDKCCRKHNLNGKRKEQVQPAAIAAPAAAAAAVAVAVAAGAYLEHRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAPGGLLVHIAEHGTRPYDCNLCPEKFYFRAELEHHQRAHELRPQPAAIAAAARPKQETHSSTASSPLTLSPSHVKQELYESEPANSPNAAELPVLQQQQQQQEEEEYIEVEQVPQETLRTGELLSTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: iTF_00502755;
80% Identity: -