Basic Information

Insect: Drosophila anceps
Gene Symbol: zfh1
Assembly: GCA_035045945.1
Location: JAWNON010000225.1:10675829-10702503[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.02 1.4 9.6 2.4 2 23 73 95 72 95 0.93

2 9 0.0013 0.093 13.3 0.1 1 23 294 316 294 316 0.97

3 9 3.1e-05 0.0022 18.4 1.8 2 23 330 351 329 351 0.97

4 9 1.1e-05 0.00078 19.8 6.4 1 23 360 382 360 382 0.99

5 9 0.00032 0.023 15.2 1.2 3 21 390 408 388 409 0.94

6 9 0.029 2.1 9.0 0.4 2 21 636 655 635 656 0.92

7 9 1.4e-05 0.001 19.4 0.5 1 23 1024 1046 1024 1046 0.94

8 9 5.4e-05 0.0038 17.6 7.4 1 23 1052 1074 1052 1074 0.98

9 9 0.0027 0.19 12.3 4.3 1 21 1080 1100 1080 1101 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.02	1.4	9.6	2.4	2	23	73	95	72	95	0.93
2	9	0.0013	0.093	13.3	0.1	1	23	294	316	294	316	0.97
3	9	3.1e-05	0.0022	18.4	1.8	2	23	330	351	329	351	0.97
4	9	1.1e-05	0.00078	19.8	6.4	1	23	360	382	360	382	0.99
5	9	0.00032	0.023	15.2	1.2	3	21	390	408	388	409	0.94
6	9	0.029	2.1	9.0	0.4	2	21	636	655	635	656	0.92
7	9	1.4e-05	0.001	19.4	0.5	1	23	1024	1046	1024	1046	0.94
8	9	5.4e-05	0.0038	17.6	7.4	1	23	1052	1074	1052	1074	0.98
9	9	0.0027	0.19	12.3	4.3	1	21	1080	1100	1080	1101	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCATCGTCTACACGTTTTGGCCAAGAGGATAACATTATACAGCAGAGCATGCCATCGTCCACAGCCTTCTCCATGCAGTTTTCCTCTTTGGCCTCCAGTTTGCATCATCACCAAGCCCACAACAAGCCCAGCAATGCGGCTGCCAACCCAGAGCTGGCCAGCGGCGCCACAGCGAGTGCGGCTGAGGACTGTTTGGTCAAGTGCACGCAGTGCCACAAGCGCTTCACTGAGTTTCAGTCCTTCAGCGAACACATTGCCAACGAGCATCCGCATGACAAACTCAACTATGAGTCACATCGTGCGGCAGCTGAGGCTGCGCAGCCGGAGAGCGAAGCGGAGGAGGATGAGCAGAGCAATTTGAGCAGCAGTAGTCGTCGCTATGCCAAATCTCcaaacaaccacaacaacaacaataacaacagcgaTACAGCAAAgaatcaaaacaacaacaacagcaacagtggcagtggcagtggcagtggcagccatAGAAGCCAACACTCACCGATCAACGATCTGTTTGCCCACCTGCCGCATCAGCCACCGCAGCTGCCCGCCCATTTGCATGCACAATTCATGGCCGCCGCTGCTTTGGCCATGCAATCCGCCCGATCCGCCAGTTCGcccagccaacagcagcaacagcaacaacagcagcaacagcaacaccagcaacaccagcaacagcaacagcaacagcagctgcaacagtcgccacagctgcagcaggcttTGCTGTTGCCACCGCCACAGcccggcagcaacagcagcgtcgGTAGCAACTCCGCCTATGACTTGGACCTGAGTGCACCACGCTCCACCTCCAGCCCGGGCTCCACAACGGGCGACCTCGGCGCCGCCTTTCCCTGCATGCAATGCACCGCCGCCTTTGCCAGCCGCGAGCAGCTCGAacagcaccagctgctgcactCGCCCACGGGCCCACAGACCACACAAAATGTGACACAGACCTGCAAAATATGCCACAAGGCCTTCGCGAACGTGTATCGCCTGCAGCGCCACATGATCAGCCACGACGAGTCGGCATTGCTGcgcaaattcaaatgcaaccAGTGCGACAAGGCCTTCAAGTTTAAGCATCACCTGAAGGAGCATGTGCGCATCCATTCCGGCGAGAAGCCTTTCGGCTGCGACAACTGCGGCAAACGCTTCTCGCACTCGGGCAGCTTCTCCTCGCACATGACCTCCAAGAAGTGCATTAGCATGGGCCTCAAGCTCAACAACAATCGCCAGATGCTCAAAACTCTGGACAAGAACTCATGCGCTCGACGCTCGCCCACagatcagcagcaacagcaacagcaacagctggcgGGCAAACGGAAGCTGCCCGAGCAGGTGCTGCCCAATCCGATGAATTACTTTGCCGGCGAAGTGCAAAACCCACCAACGGCTGTCAACGCTCCTGCGCCCTTCTATCCCAACTACAATGCCATGAATGCGGCCTTGTTGGCATTCCCGAATGCTTTTATGGCGGCCGCGCTGGATCCGCGCATGCATCCTTATAGCATACAACGACTGTTGGAGCTAACTGCTgccgggcagcagcagcagcagcagcgggatgagcagctggagcaggagcacAGAGAGGAACAGAAATTGTATGAGACGAGCAAGGATGATGATGAGACGCCCGATGAGCCCAAATTGGTTATGGATTTGGAGGAATCAGAGCCGAAGCCTGCGGCCAGTCCTGAATTGGCCGTCGCTGAACCTGTCGCCATCGATGTTGGCGTCGTTAAGCAGGAGCCCAGTCGCGAGCCGACGCCCCCCGACACGCCCAAGTCCATCAAAGTGGAGCATGAGGAAGAGCTGGAGGCAGCGGCCGTTGAGCAGTCGCGTACGCAGACACCGCATGATCTGCGCTGCAGTCGCTGTGCCAAGCAATTCAATCATCCCACAGAGCTGGTGCAGCACGAGAAGGTGCTCTGCGGCCTTATCAAAGAGGAGCTGGAACagcaataccaacaacaacaacatcaacaacaacaacaacagcagcaacaacagcagcaacaacatcagcaacaacagcagcaacaacaacaacaacagcagccaagctTTGCTCTGCTGCCATCGGCCAGTGATgcggatgaggatgaggaagACGAGGAGGAGCCACGCCAGGATTACCATGCTGGCAGCAGCGATAGCGGCGAGCGTAAAGTGCGCGTGCGCACCGCCATCaacgaggagcagcagcaacagctcaagCAGCACTACGCCCACAATGCGCGTCCCAGTCGGGATGAGTTCCGCATAATAGCCGCCCGCCTGCACCTGGACGCGCGCGTCGTCCAAGTCTGGTTCCAGAACAATCGCTCACGCGAACGCAAACTGCAGAGCTATGCGAGCAACGGCGAGTCCGCCGGAGCTGCCACAGCTCCAGCACTACCACAGCCACGCGCTGGCGAGGACCAGCCACTGGACCTGTCCGTTAAGCGTGATGCCTCGCCGCTGTACGGCTTGTCGGCACAGCAGGCAGCTGTGCTGCCCGCGCCCGCCGACTTTCAGGAGACCATGGCCATTAATCTGAGCCGCAAGCTGTCCGGCTCGGCGTCCATGTCGccggcgtcgctgtcgcccTGCTCGGGCGCCTCCTCGCTGCAGCAgtcggcggcagctgctgctgccgctgcggcgcTTTACTTTGCGCCCCCTTCGCCGCCCAGCCTGCACGAGTCGGCGCCCGCTTTGGCGGCGACGCACAGCGCAGCGCCGCGTGGCCAGGCATTCGCCGGCCTGCCGCCTTACATGCTGCCACGCCTGCCCATGGAGGCGCTTTTCCAGATGCGGCCCGGCGGCGACTATGCGCCCAATCCGCTCATGAACAGTATTAAGCTGCCCGACTATCGCGGCACCAGCCTTAGCCCCGGCGGCTCCGAGAAGCGCTCGTGGCGCGACGATGATTCCCGCATCTCGCACGATGATGACTATGTGCTGTCGGGTGGCGGCCTGCTGCCGCCCAAGCCCAAGCGGGCCAAAGCCGAAACGCACGGACATGCGGGTGATCCGGACCTGCCCTTTGTCTGCGATCAGTGCGACAAGGCGTTCGCCAAACAGAGCTCACTGGCGCGTCACAAGTACGAGCATTCCGGTCAACGACCCTATCAGTGCATGGACTGTCCCAAGGCCTTCAAGCACAAGCACCATTTGACGGAGCACAAGCGTCTGCATTCCGGCGAGAAGCCGTTTCAATGTTCCAAATGCTTGAAACGCTTCTCCCACTCGGGCAGCTACAGCCAGCACATGAACCACCGTTACTCCTACTGCAAGCCCTACAGGGAATAG
Protein Sequence: MLSCLAPSSTRFGQEDNIIQQSMPSSTAFSMQFSSLASSLHHHQAHNKPSNAAANPELASGATASAAEDCLVKCTQCHKRFTEFQSFSEHIANEHPHDKLNYESHRAAAEAAQPESEAEEDEQSNLSSSSRRYAKSPNNHNNNNNNSDTAKNQNNNNSNSGSGSGSGSHRSQHSPINDLFAHLPHQPPQLPAHLHAQFMAAAALAMQSARSASSPSQQQQQQQQQQQQHQQHQQQQQQQQLQQSPQLQQALLLPPPQPGSNSSVGSNSAYDLDLSAPRSTSSPGSTTGDLGAAFPCMQCTAAFASREQLEQHQLLHSPTGPQTTQNVTQTCKICHKAFANVYRLQRHMISHDESALLRKFKCNQCDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRQMLKTLDKNSCARRSPTDQQQQQQQQLAGKRKLPEQVLPNPMNYFAGEVQNPPTAVNAPAPFYPNYNAMNAALLAFPNAFMAAALDPRMHPYSIQRLLELTAAGQQQQQQRDEQLEQEHREEQKLYETSKDDDETPDEPKLVMDLEESEPKPAASPELAVAEPVAIDVGVVKQEPSREPTPPDTPKSIKVEHEEELEAAAVEQSRTQTPHDLRCSRCAKQFNHPTELVQHEKVLCGLIKEELEQQYQQQQHQQQQQQQQQQQQQHQQQQQQQQQQQQPSFALLPSASDADEDEEDEEEPRQDYHAGSSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDEFRIIAARLHLDARVVQVWFQNNRSRERKLQSYASNGESAGAATAPALPQPRAGEDQPLDLSVKRDASPLYGLSAQQAAVLPAPADFQETMAINLSRKLSGSASMSPASLSPCSGASSLQQSAAAAAAAAALYFAPPSPPSLHESAPALAATHSAAPRGQAFAGLPPYMLPRLPMEALFQMRPGGDYAPNPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHDDDYVLSGGGLLPPKPKRAKAETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00530857;
90% Identity: iTF_00559678;
80% Identity: iTF_00476523;