Danc009153.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila anceps
Gene Symbol
-
Assembly
GCA_035045945.1
Location
JAWNON010000162.1:3525464-3528339[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0015 0.1 13.1 0.4 2 23 143 165 142 165 0.92
2 12 0.00019 0.014 15.9 1.3 2 23 179 201 178 201 0.95
3 12 0.35 25 5.6 8.8 2 23 459 480 459 480 0.97
4 12 1.2e-06 8.2e-05 22.9 2.8 1 23 486 509 486 509 0.96
5 12 0.002 0.14 12.7 0.4 1 23 514 537 514 537 0.96
6 12 0.00014 0.01 16.3 4.6 1 23 555 577 555 577 0.96
7 12 0.00013 0.0094 16.4 1.2 1 23 582 604 582 604 0.98
8 12 3.2e-05 0.0022 18.4 1.7 1 23 610 632 610 632 0.95
9 12 0.00032 0.022 15.2 0.7 1 23 638 660 638 660 0.98
10 12 3.3e-07 2.3e-05 24.6 2.7 3 23 668 688 667 688 0.99
11 12 2.2e-08 1.6e-06 28.3 1.0 1 23 694 716 694 716 0.99
12 12 1.5 1e+02 3.7 5.2 1 19 721 739 721 744 0.88

Sequence Information

Coding Sequence
ATGCCTGACACCTACGACCAATTCGATGCGGAGCGCGTCTGCCGTGTTTGCCTGCGCGAGGTGGGCGACTTCTATTTCATCTACGATGAGGCGCCCGTGGAGCAGGGCGCGAACATTGCCCAAATACTTAATGAATGCACGCGCTACACCTGCGAGCGCTATGACAAAATGCCCCATCATATGTGCGACACCTGCATCAAGGCCGCCTGCCAAGCGTATCGCTTCAAACAGGACGCTGAGAAGGCCTATCGTTCGCTTGTGGCTATGCTGGGACGTACACCTGTGACCAAGCCCAACAGCAGCGATGTCTGCACCCAGACTGAGCAATTAACAATGCTGCCATGCGGGATCTGCAATGATAAATTTCTCAACATTCTCGAATTGCGTCTGCATCGTAATCGCCAGCACTTGAAAACGAAGGAGCTGAAGTGCACGCTCTGCGACGAGCAGTTCCCAAAGCTTCGTCAGCTGCGCAATCATCTCGCCGAGCAGCATGATCAAAAGTCAGCGGCGCCGTTGCTACGTCGACGTCTGGAATGTCGAGTTTGCCAACGTGCGTTCTTGCGACGCGATCATCTTATACGCCATATGCGAAATGCCCACGATGTGCCTCGGCAGCAGGAGTCGGAGCTGGAGTCCGAAGCGACCTGGACGCCCAATGACGAGACAACTATGCAAAGCGGCGATGAACTAGAATCGGCTGCCGTCTTATTCAATGACCCGGCTGCCAGTTCTGACAACGAAAACAACGAGAGTGGCTATCAATGCCATACTACAAATCCTATATCAAGCAATGAGGATTCCGCCGATGATGATGTTCATGCCGAGGCTAAAGAATCGCTCTGGCTGCACATtaagccagagccagaaccaGAGCTGGAGGCGGAGCCGGAACCTGAGCAAGTGAATCGCGATAGacgtaaaaagaaaacacaattaAAAGTTGCAGTTCACACAGATACCGAAGAGGAGAGTGAAAAGGTTAACAAGCACAAGCCTGCCTCGAGTTCGCTTGCAACGGAGGTAAAAGAGGAGCCACTCACTGCCGGCAGCGAGCAGCAATTGTCCATTAAGCAAGAGCGACAGCGCGTGGACAGCATCAAAGTGGATGAGGAGTATGAGATGGAGGCCGCAACAGCTGATCTTTTTCACAGTGCtgatgaggatgaggacgGTGACGAGGAGAGTGACATTGATGAAGAGGATGCTGAAGATGATGACGAGGATGAAGCTAATACAGAGCTCGATAAGCACAAATCAAAACTGGCTCAAGTGGAAATCGTGCGGGAGTATTTGCAGAAACCGACAGCTGGCaagcagcgacgtcgacgacgcAAAAAGACGCAAAGCGAAACGGAAGCAAATCCAGAGAATCGCTGTGATGTCTGCATGCGCACCTTCTCCCGCCATTGCCATTTGTTGCGACACAAATTGTCCCATCTGGAGAAGAAGCCGCACAGCTGTCCCCATTGTCCCAAGGCCTTTGCGCGCAGCGATCACTTAAAGGCGCACGTGCAGAGCCTGCACGGCAATAAGGAGCACAAGTGCGTACTCTGCGATGCGGCGTTCGCCCGTCTCGATGCCCTCGATCGGCACAAGATGAGCAAACACAATGGCGAGGGTCTCGACGCCAGCAACGAGCTGAAGCTCCAAATGAGCGAGCATACGTGTGAGTATTGTGCAAAGCGTTTCTCCAGCAAGACATATCTGCGAAAGCATACACTGCTCCACACGGAGTTCCTATACGCATGCAAGAGCTGCGACGAGACGTTCAAGGAGCGCCAAGAGTTGCGCAGCCACGAAAAGACCCACACCGGTCAGCGTAATTTCCTCTGTTGCATTTGCGGTGACAGTTTCGCGCGCAACGACTATCTGCGCGTCCATATGCGACGGCACAACGGCGAGAAGCCATACAAGTGTCGTTACTGCATCAAAGCATTTCCACGCGCCACAGATCTTAAGGTACATGAGCGGTATCACACGGGCACCAAGCCCAATCTGTGCAACACCTGCGGCAAGAGCTTCCATCGTGCGTACAATCTGACCATACATATGCGTACCCATACGGGCGAACGTCCGTATAAGTGTGATCAGTGCCCCAAGAGCTTTAGCCAGAGCAACGACTTGAAGGCCCACATACGACGGCACACTGGCGAGCGGTACAAGTGCCCGCATTGCGATGCCTACTTTCTGCAGCTGTATCACATGCGCAACCATTGCCTGAGCGCCCACAATAAGCATATTGAGACAAAGACGGGTCGGCTGCAGCGCACTGGCCTGCTGGACGAGCCCAATCACTCGCATCTGACCACTGTCGTAATGCCGCCAGCACGTTACCAGCCATCAACGCCCGAACCGCAACCAATAGCCACTGTTACAACGCAGCTGCCAGCGccaattgccacgcccattatGCATTCACCGGTGACCTATAGTACAACGTCGCCTGTACCTGTATCCGTGTCTGTGCCACTATCAGATGCAGGCGGATTCGTTGGTGCAACGACAAATGCAACAAGTACAACTGCGACGACGGCACCATTTGGCACGTTCAGCATAGCGCCCGTCGTGATGGCGCATCTGATGTACAATCATGGCGGGAACAGTCAGCAGAGCAATGCAAGCAAATAG
Protein Sequence
MPDTYDQFDAERVCRVCLREVGDFYFIYDEAPVEQGANIAQILNECTRYTCERYDKMPHHMCDTCIKAACQAYRFKQDAEKAYRSLVAMLGRTPVTKPNSSDVCTQTEQLTMLPCGICNDKFLNILELRLHRNRQHLKTKELKCTLCDEQFPKLRQLRNHLAEQHDQKSAAPLLRRRLECRVCQRAFLRRDHLIRHMRNAHDVPRQQESELESEATWTPNDETTMQSGDELESAAVLFNDPAASSDNENNESGYQCHTTNPISSNEDSADDDVHAEAKESLWLHIKPEPEPELEAEPEPEQVNRDRRKKKTQLKVAVHTDTEEESEKVNKHKPASSSLATEVKEEPLTAGSEQQLSIKQERQRVDSIKVDEEYEMEAATADLFHSADEDEDGDEESDIDEEDAEDDDEDEANTELDKHKSKLAQVEIVREYLQKPTAGKQRRRRRKKTQSETEANPENRCDVCMRTFSRHCHLLRHKLSHLEKKPHSCPHCPKAFARSDHLKAHVQSLHGNKEHKCVLCDAAFARLDALDRHKMSKHNGEGLDASNELKLQMSEHTCEYCAKRFSSKTYLRKHTLLHTEFLYACKSCDETFKERQELRSHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCIKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFSQSNDLKAHIRRHTGERYKCPHCDAYFLQLYHMRNHCLSAHNKHIETKTGRLQRTGLLDEPNHSHLTTVVMPPARYQPSTPEPQPIATVTTQLPAPIATPIMHSPVTYSTTSPVPVSVSVPLSDAGGFVGATTNATSTTATTAPFGTFSIAPVVMAHLMYNHGGNSQQSNASK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00532523;
90% Identity
iTF_00544635;
80% Identity
-