Basic Information

Gene Symbol
indra
Assembly
GCA_017639315.1
Location
CM029944.1:20508954-20511801[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.36 27 5.4 2.2 1 23 284 307 284 307 0.95
2 8 0.00078 0.06 13.7 0.2 1 23 315 338 315 338 0.97
3 8 0.00013 0.01 16.2 0.3 1 23 440 463 440 463 0.98
4 8 1.4e-05 0.0011 19.3 1.6 1 23 471 493 471 493 0.98
5 8 0.0018 0.14 12.6 0.3 1 23 619 642 619 642 0.96
6 8 3.2e-05 0.0025 18.1 3.4 1 23 650 673 650 673 0.98
7 8 0.00076 0.058 13.8 1.9 1 23 842 865 842 865 0.97
8 8 0.00047 0.036 14.5 0.1 3 23 899 922 897 922 0.90

Sequence Information

Coding Sequence
ATGGCAACTAAGCCGAAAAAAGAAGTGCTTTGTGATTATTGCGGAAGCAATAACGAAGCCAAGCACATTTACTCGGCCCAAAAGTCGTTCGTCAGCCGGAAAGTGTTGGAACTGCTTGAGATCATAACTCACAAAAACCTGCCCAATAATGTGGGCTTCAAGGTATGCTTTCTGTGCGCCTCCACGCTGATGTCCACCGTTGGTGTCATTGAGAAAACGCAGAAACTGGTGGACGACTGCCTTGTTACTCTTGCCAACAAGAAAAAGAAGCCAGTGGCGAAGGGAAAAGAAGTGGCAGAAGAAGAAGCGAAGGAGGCAGTACATGTGGTGGAAGAGTCCCACAGTGATTCGGAAGAGGAAGACAATCAGCCAGAGGAAGACGATGACGTGGTTGATATTACCGAAGACGGGGAAAAGCCAGAGCCAAAAATAACTACGCCAAAAATCACAACTCCTAAAATCAGTACTCCAAAAATCACTTCTCCTACCAAAAAGGTAAATACAACCATTAGGCAGCGAAGCAAGTCAATGGCTGCTCTTTCGGTGTCTCAAATAAATCACATAACCCAGAGTCCCATCGGGGGTTCGCCCAAAAAAGTCCAGCTCAAGCAGACCACTCTCGTGGACACTTCACAGGCTAAGCAAACGCCGAAAAAGCAAGATTCCCGGCAGGAGGATAACCTCATTGATTCCGTTAAGATAACGCCCTCCAAGGAGATTGCACCCAAAAAGAAGGTGTTCCTGCAGCTATTCGGCTCGAGCAATGGCGAGCAACTGGAGACCGAGAGCGACACTGACGAGAGTGACACTGAACAGAGTAAGAGATTGGTTCAGGTTACGCCTCAGGAGTTCGATTGCAGGATGTGCGACTTTAAATCAAAGTTTCCGAAGCTCTTTAAGGAGCACCTGACGAAGGAGCACGGCCAGCAGAGGCCACGAATCTATTATTGTGATGCCTGTCCCAAGAGCTTTGGTGTTCTGAAGTCACTCAAAGATCACTTGTCCACCGCTCATGGAGTGACATTGGAGAGTGCTGCCGACGCTGCAACCAAAAAACCGAAACCGAAGGAGGAGAAGCCAAAGGATGCAAAACTAAAGAAGGGAAAAGCTACGGAAGCTAAGTCCAAGCCGGAAAATGGAAAGGAAACCAAGGAGAACATACCGGAAGAGGATTCTGATGTACCAGTTGATTTAAATGCCTCCGAAGTCAAGAATAAGATTGTAGAAAAAGTAATAAACAATGATTATACATTCGCAGTGAATGGATCCAGTGCATCCACACCCATGTCTGGTTCCGATACCCCACAATTCGCTGAATTTAAGTGCGACATTTGCGACAGCGAGTTCACCAGCGCGAAACTAATGCAGGAACACATTAAGAAGGCCCATGGCATCGAGAAGCCCAAGATCTTCAAGTGCCAAATCTGCGGGAGGTCCTTGGCCACCAAGAAGACCCTGGCGCACCACATTAAATTGCACCAGGAGGGGGCCGCCGATACCAAGCGAAAGATTTTGCAGGAAGATGAAAAGGATGCTGATAATCTAGACAGTTCCAAGAAGGAGGCTGCAGCTCCAGTTGAGGGCAATACGGCTGCCAAGACAGACACCACCAAGGAAAGTAAAAAGGAGAAGGCACCGAAGAAAGTTAAAGAGGATAAGCCCAAAAATCAAGAGGCACCGATAGAAGCTCCAAAGGAAACTACCCAACCCGAGGATACAGAACGGCCTGTATCTTCATTCAAAGCCTTGAATGAGTCGGCAGTCAAGAAGAAGCGTTCCGAGAAAACAGTCACTAATGATGATCCATTCGCATTGTCGCCCGTGGTTGGAGGCGAGTCTCCGAAAGTCCCTAAATTCAAGTGCGATGTCTGCGATAGCGTGTTCTCCTCCGTCAAGCTAATGAAGAATCACGTTGAGAAGGCCCACGGCATCGAAAAGCCAAAGATCTTCAAGTGCCATATCTGCCAGAAGTCCCTGGCCACCAAGCAGACACTCACGTACCACATTAAGACTCTCCACGAGGAGGAGGCGAAGGAAAATGTGGAGAAAGATGAGGAGGATTTGGATAATGTAGACAGCCCCGTGGCGGTGGCCGAGCCGAAGAGGAAGAAGGCTGTTAAGAAGAGTCTTCCCAGGGAAGAAGGTGAGACTGCCACAACCGCTGAAGCTAAGCCCCAAGAGGTTGAAACTTTAATGGCTGCTCCCAAGTCGCCCGTCAAGAAGGTCAAGAAGGACAAGAAGCAAGCGAACAACTCCCAAGATGACTCGCTGCCTTCCGTCTCTTTGGATGGGGACAAGCTCAACAAATCCGGGAAACGCAAGCTTAAGGTCAACCAATCGGTGGACCAAGATGGGCCAGCCAGCTCCAACAATGATTCCACGATGGAGGAATCTGTTTCCTCGCAGCAGCTGCTGAACGAAGTCAACACCAACGTCCGGCCGCACAAAAAGGCCAGACTGGATTCCATAATTTCGATTGGGGAAGAGAGCAACCTGGACAGCACCACCGACGAGACCACCGACTTCAACTGCAACCAGTGCGGCAAGACCGTGACCTCGCGCAAGCGTCTGGACTCTCATATCCAGAAGAAACACGGCGTGAAGCTCCAGTGTCCGTTGTGCAAGGACAGCCACCGCCTACAGTTGGACTATGTGGCGCACTTTGCCGACTGCAGTGCTCTCGATGGTCTGCCCTGCGGTGTTCCAATGTGCAAGAAGGTCTTCGCCGATGCCAACTACCTGAGCACCCACCTCCGGAAGCGCCATCAGTGGTCTTAG
Protein Sequence
MATKPKKEVLCDYCGSNNEAKHIYSAQKSFVSRKVLELLEIITHKNLPNNVGFKVCFLCASTLMSTVGVIEKTQKLVDDCLVTLANKKKKPVAKGKEVAEEEAKEAVHVVEESHSDSEEEDNQPEEDDDVVDITEDGEKPEPKITTPKITTPKISTPKITSPTKKVNTTIRQRSKSMAALSVSQINHITQSPIGGSPKKVQLKQTTLVDTSQAKQTPKKQDSRQEDNLIDSVKITPSKEIAPKKKVFLQLFGSSNGEQLETESDTDESDTEQSKRLVQVTPQEFDCRMCDFKSKFPKLFKEHLTKEHGQQRPRIYYCDACPKSFGVLKSLKDHLSTAHGVTLESAADAATKKPKPKEEKPKDAKLKKGKATEAKSKPENGKETKENIPEEDSDVPVDLNASEVKNKIVEKVINNDYTFAVNGSSASTPMSGSDTPQFAEFKCDICDSEFTSAKLMQEHIKKAHGIEKPKIFKCQICGRSLATKKTLAHHIKLHQEGAADTKRKILQEDEKDADNLDSSKKEAAAPVEGNTAAKTDTTKESKKEKAPKKVKEDKPKNQEAPIEAPKETTQPEDTERPVSSFKALNESAVKKKRSEKTVTNDDPFALSPVVGGESPKVPKFKCDVCDSVFSSVKLMKNHVEKAHGIEKPKIFKCHICQKSLATKQTLTYHIKTLHEEEAKENVEKDEEDLDNVDSPVAVAEPKRKKAVKKSLPREEGETATTAEAKPQEVETLMAAPKSPVKKVKKDKKQANNSQDDSLPSVSLDGDKLNKSGKRKLKVNQSVDQDGPASSNNDSTMEESVSSQQLLNEVNTNVRPHKKARLDSIISIGEESNLDSTTDETTDFNCNQCGKTVTSRKRLDSHIQKKHGVKLQCPLCKDSHRLQLDYVAHFADCSALDGLPCGVPMCKKVFADANYLSTHLRKRHQWS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

90% Identity
iTF_00477567;
80% Identity
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