Basic Information

Insect: Drosophila ananassae
Gene Symbol: Hivep2
Assembly: GCA_017639315.1
Location: CM029942.1:808128-817015[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0006 0.046 14.1 0.2 1 23 180 202 180 202 0.98

2 8 0.0052 0.4 11.1 2.1 1 21 208 228 208 232 0.88

3 8 0.009 0.69 10.4 0.1 1 19 667 685 667 688 0.93

4 8 2e-06 0.00015 21.9 2.0 1 23 1380 1402 1380 1402 0.99

5 8 7.3e-06 0.00056 20.1 3.5 1 23 1408 1432 1408 1432 0.92

6 8 3.7e-05 0.0028 17.9 3.6 2 23 1887 1908 1887 1908 0.97

7 8 0.00057 0.044 14.2 1.2 1 23 1914 1938 1914 1938 0.91

8 8 0.0018 0.14 12.6 2.7 1 23 1959 1983 1959 1983 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0006	0.046	14.1	0.2	1	23	180	202	180	202	0.98
2	8	0.0052	0.4	11.1	2.1	1	21	208	228	208	232	0.88
3	8	0.009	0.69	10.4	0.1	1	19	667	685	667	688	0.93
4	8	2e-06	0.00015	21.9	2.0	1	23	1380	1402	1380	1402	0.99
5	8	7.3e-06	0.00056	20.1	3.5	1	23	1408	1432	1408	1432	0.92
6	8	3.7e-05	0.0028	17.9	3.6	2	23	1887	1908	1887	1908	0.97
7	8	0.00057	0.044	14.2	1.2	1	23	1914	1938	1914	1938	0.91
8	8	0.0018	0.14	12.6	2.7	1	23	1959	1983	1959	1983	0.92

Sequence Information

Coding Sequence: ATGCTAAACAGTCCGAGGAGCAGCAGCAGCAGTCGAAAGTTCAAGCGATTGGCCAGCACCACCGAGGTGGAGAACGCCAACGGCAATGGGAATCTGTCTGGGGATGCCGGTCGCACCACATCGCTGTCCTCAAATAGTTCACTTTCGCCGCCACCACCGCCGATGGTCGCCAATGGCCACCACTTGACCCAACCGCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGCCAACTTTGTAAATAGCAATCATGTCAATGCCATCGGTCAGGAGGAGAGCCAGAAGGCAGTGCCCAGAACGCGAACGCCGCTGAGCAGCAGCAATAGCAACACAAACAGCAACTATGCGGCAAATGCCACACTGTCGCCGGCAACATTCGCCCAGCACCAGCAGTTGACGCAGCCAACGGCAGGAGGTGGAGTGCCAGGTGGCGGAGGAGGAGGTGGTGGCGGTGGAGTTACTACTCCCGCAGGTGAGAAGGCCGGACGATATGTCTGCCCGTATTGCAGTTTGATTTGTGCCAAGCCCTCGGTGCTGGAGAAGCACATCAGGGCACATACCAACGAGAGACCCTATCCCTGCGATCCCTGCGGCATTGCCTTCAAAACGAAGAGCAATCTGTATAAGCACTGCCGCTCCAGGTCGCATGCAGCCAGAGCCCGGGGCTTGGAGGTGCCACCAGATGCGGATGATGGTCTCTCCGACCAGGATGCGGACCTGAGTAACAGTAGTTCCGAGTTGCCAAGTCGCGCTGGATCGCCATATGATGAGCCCATGAGCTCGCCCACACCCTCACCCTCCACCTTGTCGGCGGCGAAGAGCGCCTACATCCAGCAGCCGCCACTCCCCCAGCACATGCAACAGTTGCCGCTGGGATCGCCGGCCGCTGGGACTCTACCACCCGCCACGGCGGACAACCTGCACTCGGCCACTGCCCAGCACCGGTCGTCTGTCGACTACAAGCCATACAAGCCCAAGTTCCACAACGCCTCGCTTTACGCTCCTGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTGCACGCCCAGCAATCGCTCCTGGTCGGCCTGCCGCCGGTGCCCCCAGCTGGGGTGTACTACTTGGGCCAGCCTCCCTATTACAATCAGGATCCTACCGCGGCTGCGATCCATCAGCAGCTAGTCCTCCAGCAAATCCAACTGCAGCAACACATCCACCTGGCCCAACAGCAACAGCAACAGCAGCAGCAGCAGCAACACTCTCCGTTGGTTAAGGCACCGCCGCCAATGGCACAGCCGCCCAGTGTTCCCCCGCAACAGCTGGTGCGAGCCAACAGTCAGGTTTCCAGTGTAACCCCAGCACCGGCCACTCCCTCGCCCGCCACAAATCTCAGCAGTTTCGCGAGCTCCAGCGGCGGCATGCAAGTGAATGTGGCCAAAGTTCAGGAGCACATATCGAAGCTGATTTCGCACAACGAGGCCATTACAATGCAGTATCGCCAGGATCCGGCCACCCCGGTGGCCAAGATGGACCAACAGGCGATGGGGGTGCATGTGATGCCTTTGAACTTGTCGGCGAAACCGAAGCCCGCCGTAGTTAGTCTGCCCGTCAGCTCCATAGCCACCAGTTCCGTGGCGTCCACCCCCACCACCTCCACAGCTCCTACGGCCAGCGGCTCGAAAACTGCCCCACCCACTGCCCAGCCAAACAACTCCATCATCAAAAACCTCCTGTTGAACGCTCGGGGACTAGCCGTGCCCATTGGAGAGGGCGACGACGCTGTCTACTCGTGTCCCATTTGTGCCAATGAGTTCCGCAGTGCGGACGAGCTGAAGCAGCACAACAGCACCTATTGCCAGGATGCGAGCTCCAGCGCCCCCATGAGTCCGGCCTCATCGCCCTTCCGCTCCAACTCGATCTCGCTCAGCCTGCCGGAGCTGAAGAACCACATTGCCAACTCAAAGAATCCTCTGTCGCTGGCCAAGCTGGCCTGGTGTCAGCTGAAGACCAAGAGGAGCTGCCTGGTCCTCAATCGCCTAAATGCGGCTCAAACGCACGCAAGGACCTCTACGGTGACAGCACCCACAGCCACTCCTCCGGCCACTGCTCCTGCCACTGGTGCGGGCCCTGCTCCTGCTCTTTCCAGTGCCACTCCAGCCACTCAACCAATAGTTGCTCCCACAGCCATCGAAGCTCTGCGCTTCGTGGACGCACCACTGCCATCGCCAGGACCTCTCCTCGGAAAGACGCCACTGGTGGACTTTGCCCAGCAGAACACACCCCGCAAGGCCCAAGACTCCGTTGTCATTACGAAAATGCACGAGGACCGGCAGTTCCCTGTCGACTTGGAAGCTCAGCCGGCCAAGCGAGTAAAGACCAGCGATGTCGTCATAGTTCCTTCCCAGACTCAGCCGCAGGTCTTCACATTTCCCTTCAGCAGCGTCTCGGAGTCGCAGTCCAGCAAGGAAGAGCGCTTGCGGAGATTGACGTCCTCTGGAGGCACCATGATTCCCATCTCGGAGTGCCCCGAGCTGGAGAAGAGTCCCAGGGTGATACGTACTTCGCTGTTGTCGGGCGGAAGCTTCCAGGAGGTCGGAAGTGCCTCCAAGGTCAACGAGCCGGGATCGGGCAAGGACCGGAAGCTACTGCCGCTGCCCGGTGGCCTGTCCACGGGCGCCCAGCACTTTCAGTTCCCGCCCATCAACTCGATTACTGCCTTCAATCCTCTGACCCTGCCGCAGATGGGCGGTGGGGACAAGGCTACCCCCAGCACACCGATTCCCTACGTGCCGGGCATCCCAGGACCTGGCAGTCTGACGCCTCAGATGCCCCTGCTTCCGCCGCCGCCGCAACAGTTGCAGCTGCCGGTGCCCACGGGTCGCGGCCGCAGTCCGAACCGGAAGCAGCCCAGTCCGCTCTTGATGGCCAGCGCAGCTGCTGGCGAACTGAAGGCGTTGTCTCCCTTCGGCGGAGTTCAGAATCTTCCCAGCGAGTTCAGCCGACTGCCGCCAACGCCCGCCCAGCGTCAGGCCCTCCAGTGGAACAGCAAGGAGGCCGGCAAGAAGGCGCCGTTCAACTTCCTGCGAATGGCCGACAACGTAAAGATCTCTGAGCCGGAGGTGCGTCACTTCAACCTGGACAGCGTGATTGCCGGAAAGCAGCAGCAGGAGTCGCCATTAACGCCGCTCCACGTGGACACGCCCAATGGAGTAGCCACCGAGGAAGCGAGTGCCCCCTCCACGTCCAGTTCCTCCGCCAAATCCAAGTTCCTGCGACCCACTAGCTTGCCTTTGAAGCCGGGAACGTTTACCCCGAAACGCCATCATGGAATCACTCCCACGGCCAATACACTGCCACTCATTTCTCCGGAGACGCCGAGGCCGTCGAAGTCCTGCGTCCAGCTGTATCTGAACGGGCATGCCTACACCTACCTGGGCCTGAAGTGCAGCACCAAGATGTTCTACTGCACGGTGAACTGCCCGCAGCCCTCGTACGTGGCCGGCATGCACAAGCTGTCGATGTACAGCGTGTGGCAGGTGTGCGAGGAGAACCAGCCGCATCCTCTGGGCTTCAAGCTGAAGCAGGTCATGGGCCTCTACGACTCCCGCCAGCGGATGCTGGGCAACGTGAGCACCACTGCGATGGCTGGAACTGGGAAGCTGAGCTACGGCCTGGTCTCGTCCCAGCAGATCGTGTGCTCCCCCTCGCCCAACGCCAGTGGCAGTGCCTTCTACCAGGCCCAACAGAAGTCGGCGCCAGCCGTCCAGGTGGGCGCTCTCAGCGAGGCGAATGTGGCGGCCAAGGCGGCCAACGACGAGGCGCAAGCCAAGAAGCTGGAGACCAGCCCCTCCGGACAACCGCTGGTGGGCGGATACGAGTCGCACGAGGACTACACCTACATCCGGGGCCGAGGAAGAGGCAGGTATGTCTGCTCCGAGTGCGGCATTCGCTGCAAAAAGCCTTCCATGTTGAAGAAACACATTCGTACACATACGGATGTGAGGCCTTTTACATGCAGCAACTGCAATTTCAGCTTCAAAACCAAGGGGAACCTGACCAAGCACATGCAGTCCAAGACGCACTTCAAAAAGTGCATGGAACTGGGCATCAATCCGGGACCCATGCCCGCTGATGGCGAATTTTTGGACGTGGACATGGACTTTGATCAGCAGTCGTCCACTTCGGCCGGAGGACGCACATCCTCCATGGCCGGGGAGTCAGATTCCGATGACTTCACCGACAACGAATCGGAAAGTAGTGACACGGATGAGTCGAAATCGCGGCTGAAGGAGCACGAGGCGGCCAGATGCCTCCTGTCGCTGTCCATGACACCGCCCATTCCTCAGAGTGTCTCCCCTTATCCGCAACTGCAGGATACACCTGTTCCGGCCGCCAGCCCGGCCAACAGTATTGGATCCTCGGGATCGCAGCCAAAGCGATTGGTTTGCTCCTTCACCTCACCGAAGCCTCCGTTCGACTACCAGAAGCAGGAACAGTATTACTCCAATCCGGAGGAGTCCAAGCCGAAGCGAAGCGTGGCCAGCGAGGAGAGCGCTCCCATGGATCTCACCAAGCCACGTAGCTCTGCGTCGGCCATCTCGCCCTTGCCGCTGGTCCCGCCTGTGCAGGACCTCCCCAAGTCACAGGCCCAGCAGATGCGCGAGGTGATCTTCGGCAGCTCTGGCAACGAGAGCGGCTTCATGAAGACCCTGATCTCGGTGTCGGACAAGGTGCGCATCTCCGCCGAAATGGAGGAGCAGGCCAAGCTGGGGGCCGAGGGCGAGGACGTGCTGCTGCAGACGTACATCAAGGAGCAGGCTCTCCACCACGCCAAGATGAAGCAGAGCCAGTTCAGCCGCAGCTACTTGATCAATACCCTGTTCTCCACTGCGGCGCCGGTGATGAGCAGCAGTGCCAATCTGCTGACCACCACCAGCCGGCCAGTCATGAGCATAAACGAGGTGCCCAGCATCGAAGTGCACGAGGTGAAGACACCGGATGAGGTGCCGTCTGTGGCTCCTGCTATTCCAGCTCCAGTGCCGGCTCCAGCTCGCTCTGCTGTCGCACCCGTTGCCAACACAGCTCCGGAGGAAGGAGAGGAGAGCGATCACGAGAAGTCCAAGGTGGAGCGACACAATGCCAACTTGCCGGCTGCAGTGCAACAGCCGGATGTCAATGACTTCAGCGGAGTGCTGAGCGGCCCGGCCCTTGCCACAACTACACCTGCAGTATCTGTGGCCACGTCCACTCCCGCACCTGTGGTCACATCCAGCACCGCCTCCACACCCAGCGTCTCATCCCAGCCCACGCAACGCACTGTGATTGTGGGCGAAGATGGCTTCAAGAACTCCACGCCCAGCAGCAAGAGCAGCGATCTCCAGTCGGGTCCCTACGCCCGGGGCATGCCATCAGCTCCTCCGCCGATCGCTGCCGATGCCCGGCCCACCTGCACCATCTGCTCGAAGACGTTCCAGCGGCAGCATCAGCTCACCCTCCACATGAACATCCACTACATGGAGCGGAAGTTCAAGTGCGAGCCCTGCAGCATCTCCTTCCGCACCCAGGGCCATCTGCAGAAGCACGAGCGATCCGAGGCGCACAAGAACAAGGTGATGATGACGTCGACGTTCGGAGTGCCCACCACATCCAATCCGCGTCCCTTCGAGTGCACCGACTGCAAGATCGCCTTCCGCATCCACGGGCATCTGGCCAAGCATCTGCGCTCCAAGACTCATGTCCAGAAGCTGGAGTGCCTGCAGAAGCTGCCATTCGGAACGTACGCGGAAATCGAACGGGCTGGCATCAGTCTCACGGAGATCGACACCAGTGACTGCGAGAATTCGTTGATTTCCCTGAAGCTACTGGCCCAGAAGCTGCTGGAGAAGGATCCCAACAAGCTGAGTGGCTACACCACGCCGTCGGGAATGATGCAGCTGGCCCAGGACGCCACTGGCCCGACCTCGCAGGACAGTGCCTCCGAGGATGGCTTCAGTGCCGCCATAGCCTCGGCCATTGCATCGCTGGACAACGACAGTGCTGGGAACACACCGAAGCGTGCCAGTTCCATGTCCGAGGACGAGACAGTGACCAATGGCCTGAACCACAATCTGAAGCGACGCTTGCCGGGAAGCTTTAGCAGCACCGGCGAAGAGAGCGACAATCCGGCGGAGGGCACTGTCGAGAAGCGGGCGCGATCCGGACAACCGGAGTTGCCAGCTCCTGTGCCCGTGGCTGTTCCGGTGGCCGCCTCAGCGGCAGCCAGCAACTGA
Protein Sequence: MLNSPRSSSSSRKFKRLASTTEVENANGNGNLSGDAGRTTSLSSNSSLSPPPPPMVANGHHLTQPPXXXXXXXXXXXXXXXXXXXXXXXXXXANFVNSNHVNAIGQEESQKAVPRTRTPLSSSNSNTNSNYAANATLSPATFAQHQQLTQPTAGGGVPGGGGGGGGGGVTTPAGEKAGRYVCPYCSLICAKPSVLEKHIRAHTNERPYPCDPCGIAFKTKSNLYKHCRSRSHAARARGLEVPPDADDGLSDQDADLSNSSSELPSRAGSPYDEPMSSPTPSPSTLSAAKSAYIQQPPLPQHMQQLPLGSPAAGTLPPATADNLHSATAQHRSSVDYKPYKPKFHNASLYAPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLHAQQSLLVGLPPVPPAGVYYLGQPPYYNQDPTAAAIHQQLVLQQIQLQQHIHLAQQQQQQQQQQQHSPLVKAPPPMAQPPSVPPQQLVRANSQVSSVTPAPATPSPATNLSSFASSSGGMQVNVAKVQEHISKLISHNEAITMQYRQDPATPVAKMDQQAMGVHVMPLNLSAKPKPAVVSLPVSSIATSSVASTPTTSTAPTASGSKTAPPTAQPNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADELKQHNSTYCQDASSSAPMSPASSPFRSNSISLSLPELKNHIANSKNPLSLAKLAWCQLKTKRSCLVLNRLNAAQTHARTSTVTAPTATPPATAPATGAGPAPALSSATPATQPIVAPTAIEALRFVDAPLPSPGPLLGKTPLVDFAQQNTPRKAQDSVVITKMHEDRQFPVDLEAQPAKRVKTSDVVIVPSQTQPQVFTFPFSSVSESQSSKEERLRRLTSSGGTMIPISECPELEKSPRVIRTSLLSGGSFQEVGSASKVNEPGSGKDRKLLPLPGGLSTGAQHFQFPPINSITAFNPLTLPQMGGGDKATPSTPIPYVPGIPGPGSLTPQMPLLPPPPQQLQLPVPTGRGRSPNRKQPSPLLMASAAAGELKALSPFGGVQNLPSEFSRLPPTPAQRQALQWNSKEAGKKAPFNFLRMADNVKISEPEVRHFNLDSVIAGKQQQESPLTPLHVDTPNGVATEEASAPSTSSSSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKLKQVMGLYDSRQRMLGNVSTTAMAGTGKLSYGLVSSQQIVCSPSPNASGSAFYQAQQKSAPAVQVGALSEANVAAKAANDEAQAKKLETSPSGQPLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSNCNFSFKTKGNLTKHMQSKTHFKKCMELGINPGPMPADGEFLDVDMDFDQQSSTSAGGRTSSMAGESDSDDFTDNESESSDTDESKSRLKEHEAARCLLSLSMTPPIPQSVSPYPQLQDTPVPAASPANSIGSSGSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRSVASEESAPMDLTKPRSSASAISPLPLVPPVQDLPKSQAQQMREVIFGSSGNESGFMKTLISVSDKVRISAEMEEQAKLGAEGEDVLLQTYIKEQALHHAKMKQSQFSRSYLINTLFSTAAPVMSSSANLLTTTSRPVMSINEVPSIEVHEVKTPDEVPSVAPAIPAPVPAPARSAVAPVANTAPEEGEESDHEKSKVERHNANLPAAVQQPDVNDFSGVLSGPALATTTPAVSVATSTPAPVVTSSTASTPSVSSQPTQRTVIVGEDGFKNSTPSSKSSDLQSGPYARGMPSAPPPIAADARPTCTICSKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMMQLAQDATGPTSQDSASEDGFSAAIASAIASLDNDSAGNTPKRASSMSEDETVTNGLNHNLKRRLPGSFSSTGEESDNPAEGTVEKRARSGQPELPAPVPVAVPVAASAAASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00550443;
90% Identity: -
80% Identity: -