Dana010737.1
Basic Information
- Insect
- Drosophila ananassae
- Gene Symbol
- -
- Assembly
- GCA_017639315.1
- Location
- CM029942.1:34326334-34329702[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.02 1.6 9.3 0.5 2 23 39 60 38 60 0.96 2 13 0.0033 0.25 11.8 1.1 1 23 66 89 66 89 0.94 3 13 0.038 2.9 8.4 0.9 1 19 101 119 101 122 0.93 4 13 0.043 3.3 8.3 1.4 3 22 139 158 137 158 0.90 5 13 0.29 22 5.7 2.0 2 23 407 429 406 429 0.94 6 13 0.012 0.88 10.1 0.3 1 23 454 476 454 476 0.97 7 13 0.0046 0.36 11.3 1.6 1 23 484 508 484 508 0.95 8 13 0.1 7.9 7.1 2.4 2 23 513 535 512 535 0.95 9 13 0.00026 0.02 15.2 0.2 2 21 548 567 547 568 0.93 10 13 0.0078 0.6 10.6 0.4 3 23 578 598 576 598 0.97 11 13 7.9e-07 6e-05 23.2 2.8 1 23 604 627 604 627 0.98 12 13 3.1e-05 0.0024 18.1 1.4 1 23 633 655 633 655 0.98 13 13 0.00029 0.022 15.1 2.9 1 23 661 683 661 683 0.95
Sequence Information
- Coding Sequence
- ATGGCCTCAGAGTCGATGGCCCCCAGCAGCAGCAGCGGCGCCGCCGCCGCCGCAGCAGCCGCTGCTGCCACCAAACTCCTGGTGGAGATCTCCACGGACGGAGTACCCAAGCTGCACTGCCCGGTGTGCAACAAGGCCCTTTTCTCGCTTGCCGGCTATGTGAAACATGTGAAGAAGCACCAGCCTCCAGGCGGCTTTGAATGCCGGCAGTGCGACGCCCGCTATTGCAGCGAAGAGGAACTGACCCAGCATGTTAAGGATGAGCATCCAGATAGTGGCTCCGCCCCAGAGGACAAGCCATATGTGTGCGACAAGTGCGGCGTGGAGTACATGTACCAGGAGGCCTATCGCCGCCACTGTCGTACCAAGTGTGGCGAGGAGAAGCTGTCCAGGGAGGAGTCTCGACCTGTGGAGTGTCAGTGCTGCTCCACTCGCTTTTCCACCGATGCCAACCTGGAAAAGCACCGACGCAGTCGTCCTGACACTTGCGGCCAGCCGGAGTACGATCCGCCTGGCAGCTCGAACCAGGAAATGAAGCGCAAGAATCGCAAGAAGATGAAACGAGCTGACTCCGACGAGGAAACCACCTCCGACGAATCCGAGGTGGACAGCGACGATGACATTCCCCTGGCCAGCCGGCTAAAGACGAAGCTAAAGCAGGAGAGCCAGAACTCTGATTCGGGTGACGAGTGCCCCGATTTCGAGCCGAACAACAGTGAAGACGAGGCGTTCCCGTTGCCGCCACCGGCCATGGTCAAGGTGGAGGCGTTCGACGAGGAGGACTTCGAGTACCAGGACGCCAGCATGTATGTGAAGACCGAGAGCACGGATATCTTCAGCAATGAGAAGGACAAGCTATTGGATGTCTTGCTGAACGAGGGCGACGGCCTGAAGCCGTTCGAGAGCCTGAAGGTGGAACAGGGCGCCGGCATTTTAGATGAGATTGCGGCCGTGCCGCTGGTGGAGGTGGCCGAGGAGGATGTCCTTGCGCTGCGTGGCTCGCGCCCAGATAAGCCTGGGATGAAGAGGCGTGGCAGACCGCCGAAGGGAGAGCGAAGGGAGCCGTCGGAACCGGTCGTTAAGAGAAAGTATCGCAAGAGAAACACAAGATCGCCTTCGCCGGACGAATACTCTTCTGGACCGAGGCGCATGGCCAAGATCACTAAGAAGGAACTGAAGGAACGCCTCAAAATGATCAACAAGATGGAGAAGTCCTGGAAGTGCCCGCACTGCGTCAAGATCTACCACATTCGCAAGCCCTATGAGAAGCATCTGCGCGACGATCACAAGCTAACCGAGCAAGAGATGCGCGAAATCTTCAAGGACGTTGACGTTCACGCCAAGCTGGATGAGGAGGTATTCAAGTGTCCCATCTGCAGCAAGATCTACCTGGTCGAGAAGCGCCTGGTCACCCACATGAAAGTTCACGGCGAGGATGGCAATCTGACGTTCAAGTGCCCCTGCTACTGCAATCTTTTCTTCGCCACCAAGGAGCAGGCCACGGAACATGCCCGCGCCCAGCACAAGGAACTGCTCTACTGCGAGAAGTGCGACAAGTATATGACGGGTCACGACAGTCTCAAGAACCACGAGCGCAACTTCCACTCCAAGCGAGAGCCACGCAGCCAGGTGCGCAACCTTATCTGCGACAAGTGTGGCAAGAAGTTCACCGGTCGCACCTCACTCTCCGATCATGTGCGCTCGGACTGCGGCCGCCTGCCACTCTACGGCTGCTCCGTTTGCGGCAAGCATCTTTCCACTGCTGGCATTCTCAAGACTCACATGCTGCTCCACAAGGCAGACACTCCATACCAGTGCGACAAGTGCGGCAAGACGTTCAAGGTGAAGGCACAGTACAAGTCGCACTTGAAGACGCGACACACGGACTACAAGCCCTACAAGTGCCACCTCTGCCCCAAGGAGTATCCGTACAGGGAGAGTTTGCTCACCCACATGACCGTACACACTGGCATTAAGCGATTCCTGTGCAATAACTGCGGCAAGCGGTTCACATGCATCTCCAATCTGCAGGCCCACCGCAAGGTGCACGCCGACACCTGCGGCCAACTGCCCCTCAACGCCAAGGCAACACAATACATGGGCGTGCAGCGCGGAAAGCTACTGATGGGCGCCAAGCCGGAGGCGGGAATGGCTTACGACGAAACCAAGACCCTGATCGCCGAGGAGGTCATCGAGAAGGATATGCCAATGGCCCAGGAGCTAAACTTCCCCTCGGACGGCTCGGCCCCACTAGCCACCGTGCCCCTTAACTACGCCTCCACGCACCTGGTGCCCCACATCGTTCTCCAGACCATGCAGGCTGAGGCACGGCGGCTGGAGTAA
- Protein Sequence
- MASESMAPSSSSGAAAAAAAAAATKLLVEISTDGVPKLHCPVCNKALFSLAGYVKHVKKHQPPGGFECRQCDARYCSEEELTQHVKDEHPDSGSAPEDKPYVCDKCGVEYMYQEAYRRHCRTKCGEEKLSREESRPVECQCCSTRFSTDANLEKHRRSRPDTCGQPEYDPPGSSNQEMKRKNRKKMKRADSDEETTSDESEVDSDDDIPLASRLKTKLKQESQNSDSGDECPDFEPNNSEDEAFPLPPPAMVKVEAFDEEDFEYQDASMYVKTESTDIFSNEKDKLLDVLLNEGDGLKPFESLKVEQGAGILDEIAAVPLVEVAEEDVLALRGSRPDKPGMKRRGRPPKGERREPSEPVVKRKYRKRNTRSPSPDEYSSGPRRMAKITKKELKERLKMINKMEKSWKCPHCVKIYHIRKPYEKHLRDDHKLTEQEMREIFKDVDVHAKLDEEVFKCPICSKIYLVEKRLVTHMKVHGEDGNLTFKCPCYCNLFFATKEQATEHARAQHKELLYCEKCDKYMTGHDSLKNHERNFHSKREPRSQVRNLICDKCGKKFTGRTSLSDHVRSDCGRLPLYGCSVCGKHLSTAGILKTHMLLHKADTPYQCDKCGKTFKVKAQYKSHLKTRHTDYKPYKCHLCPKEYPYRESLLTHMTVHTGIKRFLCNNCGKRFTCISNLQAHRKVHADTCGQLPLNAKATQYMGVQRGKLLMGAKPEAGMAYDETKTLIAEEVIEKDMPMAQELNFPSDGSAPLATVPLNYASTHLVPHIVLQTMQAEARRLE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00615081;
- 90% Identity
- iTF_00546135;
- 80% Identity
- -