Basic Information

Insect: Drosophila ananassae
Gene Symbol: prg
Assembly: GCA_017639315.1
Location: CM029942.1:44392268-44394037[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.13 10 6.7 0.6 1 23 210 233 210 233 0.90

2 9 0.00045 0.034 14.5 0.5 1 23 239 262 239 262 0.98

3 9 4.4e-06 0.00034 20.8 0.5 1 23 268 290 268 290 0.98

4 9 2.5e-08 1.9e-06 27.9 2.0 1 23 296 318 296 318 0.99

5 9 0.00013 0.01 16.2 0.6 1 23 324 346 324 346 0.98

6 9 4.8e-06 0.00036 20.7 1.3 1 23 352 374 352 374 0.98

7 9 4.4e-06 0.00033 20.8 0.6 1 23 423 445 423 445 0.96

8 9 2.4e-05 0.0018 18.5 0.3 1 23 450 473 450 473 0.91

9 9 0.047 3.6 8.1 2.5 1 23 477 499 477 499 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.13	10	6.7	0.6	1	23	210	233	210	233	0.90
2	9	0.00045	0.034	14.5	0.5	1	23	239	262	239	262	0.98
3	9	4.4e-06	0.00034	20.8	0.5	1	23	268	290	268	290	0.98
4	9	2.5e-08	1.9e-06	27.9	2.0	1	23	296	318	296	318	0.99
5	9	0.00013	0.01	16.2	0.6	1	23	324	346	324	346	0.98
6	9	4.8e-06	0.00036	20.7	1.3	1	23	352	374	352	374	0.98
7	9	4.4e-06	0.00033	20.8	0.6	1	23	423	445	423	445	0.96
8	9	2.4e-05	0.0018	18.5	0.3	1	23	450	473	450	473	0.91
9	9	0.047	3.6	8.1	2.5	1	23	477	499	477	499	0.98

Sequence Information

Coding Sequence: ATGTTTATTTCGGAGCCCGAAGACTTCCTGGCGTCGAGTGCGAGCTCGTGTCGTCTTTGTCACCGCGAAGCTAGCATCGACTCGCCAAACATCTTTGATAGTTCTCCGAAGTTCTGCAAGGACATGAGCATTGCCGACGTTTGCCAGCGTCTTTGGGATGTCCAGTATGAACGTCACGAGTTTTTGTCGGAGCACATTTGCCCAAATTGTGTTGAGATAATGGAGGATGCAAACGAGCAACGTCGTGGAATGCAGGAGCGGGAACAGGCGCTACAGCAACAACTAATATCTCTCCTTAAGAAGGACGCCATGTATCGTCCAGGCTTGAATGGCAATCCAGGCAATTTCGAAGCAGAAGAGGGCCGTATTATCGTTGATGTGGATCCAGAAAAGCTATCAGAGACGAGTGAGGACGAGTTTCTGCTTGGATCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCATGCCGTTGGGTATGGATGCGGCTCAAATGGCGATTATGGATATGAAGACAGCGGGAGCCAATGACGATGCTAACCCAGGTGGACCACGGCCTAAGAGGGCTTTCCTGTGCCAATATTGCGACGTGGGTTTCACTCTGCCGTCCGAATGCCAGCAGCACGAACTAAGCGCCCACGACCCCAACGCACCATATTCCTGCGCCTACTGCAATCTGTGTCTGGTAACGCGACCCGCTCTGATCTCGCACATTAAGACGTTGCACGATCCGGATCGTCCTTATGTGTGTGCTCAATGCCGCAAAGGATTTGTCCGACGCTCAGATCTTAAGAAGCATACAATTGTTCATACTGGCGTGCGACCTTACACCTGCAACGTGTGCTCCAAGAGTTTCTCGCGCAACACTAACTTGACCAAGCACGTGCGCATCCATAGCGGTGTGAAGCCGTTCGTCTGCCAACAGTGTCCTCGCTCCTTCCAGACGGCAGTCGAAATGATGAAACACTCACGCTCGCACTCCGAAGTGAAACCCTTCCAATGTGGTCGTTGTTCCTACTCGTTCTCTCGCAAGGATAAGTTGTTGGCCCACCAACAGGTCCACACTCGGCGGGATGTGGAACAGCAACAGCAGCAGATGGGAGGTCTTCCGCCAATGGAGGGCGATTTGGCTCAGTACCAACAATTTCACCAGCAACCTATCCAAGTGAAGCCAAAGCCTCCTATGCAACCTAAATCCTCCCGAAGTTTCCGATGCGATATCTGTGACAGGGTGTTCCAGCGGGAGCGGGACTTGCAGCGTCATAGAGCTCTCCATATGGACTCACTGTTTGCTTGCAAGATCTGCAATATGGGATTTAATCGACGGGAGCAGCTGCAGCGTCACGAATTGGAAGCCCATGGACCCAGCTACACGTGTAGCATTTGCTGCATCAGTTTCCTTCATCAGGTGGAACTAGAGAATCACTTGAAGGTACATCAACTGCAGCACAAAATGGTCCAGAGTGCCCAACAAGCCATCAATGCGGCCGCTGTCATGCCACACAAAGTAATGGATCAAGCTCCAGTGCCAATAATGGCCCCTGTAGTGCAGGAGCCGATGCCAATGCGTCCCTCGGCAGCCGAACTTTCTTTCTATAGCAACATGATACCCACTATGAACTTGGGTTTCTACAGCGAAACGCGTCCCGAAGAATAA
Protein Sequence: MFISEPEDFLASSASSCRLCHREASIDSPNIFDSSPKFCKDMSIADVCQRLWDVQYERHEFLSEHICPNCVEIMEDANEQRRGMQEREQALQQQLISLLKKDAMYRPGLNGNPGNFEAEEGRIIVDVDPEKLSETSEDEFLLGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPLGMDAAQMAIMDMKTAGANDDANPGGPRPKRAFLCQYCDVGFTLPSECQQHELSAHDPNAPYSCAYCNLCLVTRPALISHIKTLHDPDRPYVCAQCRKGFVRRSDLKKHTIVHTGVRPYTCNVCSKSFSRNTNLTKHVRIHSGVKPFVCQQCPRSFQTAVEMMKHSRSHSEVKPFQCGRCSYSFSRKDKLLAHQQVHTRRDVEQQQQQMGGLPPMEGDLAQYQQFHQQPIQVKPKPPMQPKSSRSFRCDICDRVFQRERDLQRHRALHMDSLFACKICNMGFNRREQLQRHELEAHGPSYTCSICCISFLHQVELENHLKVHQLQHKMVQSAQQAINAAAVMPHKVMDQAPVPIMAPVVQEPMPMRPSAAELSFYSNMIPTMNLGFYSETRPEE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00550398;
90% Identity: iTF_00481690;
80% Identity: -