Basic Information

Insect: Drosophila ananassae
Gene Symbol: Kr-h1
Assembly: GCA_017639315.1
Location: CM029942.1:46421168-46423688[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0033 0.25 11.8 3.0 1 23 137 159 137 159 0.98

2 8 1.4e-06 0.00011 22.4 0.5 1 23 217 239 217 239 0.99

3 8 1.7e-05 0.0013 19.0 2.3 1 23 245 267 245 267 0.98

4 8 3.6e-07 2.8e-05 24.2 2.8 1 23 273 295 273 295 0.99

5 8 2.7e-07 2e-05 24.7 1.3 1 23 301 323 301 323 0.98

6 8 9.2e-05 0.007 16.7 1.4 1 23 329 353 329 353 0.99

7 8 0.68 52 4.5 2.8 1 23 359 381 359 381 0.94

8 8 7.3e-07 5.6e-05 23.3 0.6 1 23 387 409 387 409 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0033	0.25	11.8	3.0	1	23	137	159	137	159	0.98
2	8	1.4e-06	0.00011	22.4	0.5	1	23	217	239	217	239	0.99
3	8	1.7e-05	0.0013	19.0	2.3	1	23	245	267	245	267	0.98
4	8	3.6e-07	2.8e-05	24.2	2.8	1	23	273	295	273	295	0.99
5	8	2.7e-07	2e-05	24.7	1.3	1	23	301	323	301	323	0.98
6	8	9.2e-05	0.007	16.7	1.4	1	23	329	353	329	353	0.99
7	8	0.68	52	4.5	2.8	1	23	359	381	359	381	0.94
8	8	7.3e-07	5.6e-05	23.3	0.6	1	23	387	409	387	409	0.98

Sequence Information

Coding Sequence: ATGGTTTACTATCCCGCTAACCAGCTTCTGATAAAAACAGAGCAACCGAGTCAGGCCCAGTTTTGCCTGCAGGTGCCACCCACTCTGACCGCCACAACGACGGCTTCCGGTCCTGGCCTGAGAGTACCAGCCTCCGGGGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTCTCCACGTCGACGCCACCAGTTAACCGGATTAAGACGGAGGTGACCGGAAACTTTGCTTCAGCCGTTGTACATCCCCAGGCGCAGACGCAGCCGCAGCCGCGCAAGACCAACGCCAACAAGCCGCAGTTCAAGTGCGAACAGTGTGGCATGACCTTCGGCAGCAAGTCGGCACACACCTCGCACACCAAGTCGCATGCCAAGAACGCCGAGCTCGCCCTGGGTGTCGGGGTGGGTGCTGGCGAGGCCGGTAGTGGTGCCGTCGCGATATCTCCAGCCATCGAGCTGAACGAGGCGGGTCTGCCGGTGGGCATTCCCAAGAGCCCGACCATCAAGCCGCTGGCGAATGTGGCTGCCGGAGCCGATCCCTATCAGTGCAATGTGTGCCAGAAGACCTTCGCCGTTCCTGCCAGGCTGATCCGTCACTACCGCACCCATACCGGCGAGCGACCCTTCGAGTGCGAATTCTGTCACAAGCTCTTCAGCGTCAAGGAGAACCTTCAGGTCCACCGACGCATTCACACCAAGGAGCGTCCCTACAAGTGCGATGTCTGTGGTCGTGCCTTCGAGCACTCTGGAAAACTCCATCGCCATATGCGCATCCACACCGGCGAACGACCACACAAGTGCTCCGTCTGCGAGAAGACGTTCATCCAGTCGGGCCAACTGGTCATCCACATGCGCACGCACACCGGCGAGAAGCCCTACAAGTGCCCGGAGCCGGGCTGCGGCAAGGGATTCACCTGCTCCAAACAGCTGAAGGTCCACTCGCGCACCCACACGGGCGAGAAGCCCTACCACTGCGACATCTGCCTCCGTGACTTTGGCTACAACCATGTGCTGAAGCTGCACCGTGTCCAGCATTACGGCTCCAAGTGCTACAAGTGCACCATCTGCGACGAGACTTTCAAGAACAAGAAGGAAATGGAGGCCCACATCAAGGGTCATGCCAATGAGATTCCCGACGACGAGGCGGAGGCAGCAGCGGCAGCAACGGGCTCATCCTCCTCGGTCGTGTCGCCATCCTCGCACGGCGTCAGTAGCGGAGTGTCGGAGAGCAGCAGCAACTCGCCGCCCAGCTCCCCGGCGGCCGTCAAGAAGCCTCGTCAGCCACGCCAGCCCCGTGGAGCCAAAGCGGCGGCGGCAGCGTCTTCCTCGGCTTCACCATTCTCGCCCAGTTCCCCCAGCTCCACGTACTCGCCCTCGACCAGCAGCCTGGCCTCGCCACCGCCCACGACGGCCCACTACCTGCCCGCCCAGGTGGAGCAGGATGCCCTAAGCCGGGACAGCGGAGTGTCCAGCGCCCAGTTGGCTCACAGCAGTTATGCGGACGAGGAGCTGCCCACGGACCTAAGCATACAGCAGGTGACGGGACAGGTTCCCACCCCAGCAGTCACCTACTACCAGGTCCCGCCCAGTCTCGTGGAGCTGCAGCCCCAGGCAGCCGGACTCACCATCAATCCGGCCCTGCTCGAGGCGGCCAGCATGGCACGACGTCATCACGACAACGACGATCAGGACCGGGAGCGCGACCAGGATGAGGACGTGCATGCCGCCGCCTGGCAAATGATTCAACTGCGTCGCGGTCATGCGGCCACGCCCCCTCTGGAGCAGCAAATGCAATACCAGCCGCCTCCGCAGCAGCAGCAACAACAGCTGCACGTCAGCGATCTGGCGGCCAACTATGATGACACCCACGAAGCAACAGTTCTCATCGAGCACTTCAAGCGTGGCGACCTGGCCCGCCACGGTCTCCACAAGGGCTATGCGCCTGTGCCCAAGTACGAATCCGCCTTGCCCAATCCGGATATCGTGCGCCGAGTGGAGGCTGCCATCGGACTGAGGTCCAGCACAGAGTCCCCTGAGCGGAGCTCCTCTCCGGAAAGCGACTCCCTGCTGATGGCCGACCGGAATGTGATGACCCTCCCGCTGCGCAAACGCAAACACTACATGAACAAGGGCGACAGCGGCCAGGTGGAGTTGGAGAAGCCCCAGGGACCGAGCGGAGAAGTCTCTTCCGCCGGCGTTGATGCATCGATGGATACCTTGGATAGTTCCGGGTCGAAGGTGATGCGGATGAGCTCTGTCATCCAGTTCGCCAAGGCCTCGTAG
Protein Sequence: MVYYPANQLLIKTEQPSQAQFCLQVPPTLTATTTASGPGLRVPASGGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVSTSTPPVNRIKTEVTGNFASAVVHPQAQTQPQPRKTNANKPQFKCEQCGMTFGSKSAHTSHTKSHAKNAELALGVGVGAGEAGSGAVAISPAIELNEAGLPVGIPKSPTIKPLANVAAGADPYQCNVCQKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIHTKERPYKCDVCGRAFEHSGKLHRHMRIHTGERPHKCSVCEKTFIQSGQLVIHMRTHTGEKPYKCPEPGCGKGFTCSKQLKVHSRTHTGEKPYHCDICLRDFGYNHVLKLHRVQHYGSKCYKCTICDETFKNKKEMEAHIKGHANEIPDDEAEAAAAATGSSSSVVSPSSHGVSSGVSESSSNSPPSSPAAVKKPRQPRQPRGAKAAAAASSSASPFSPSSPSSTYSPSTSSLASPPPTTAHYLPAQVEQDALSRDSGVSSAQLAHSSYADEELPTDLSIQQVTGQVPTPAVTYYQVPPSLVELQPQAAGLTINPALLEAASMARRHHDNDDQDRERDQDEDVHAAAWQMIQLRRGHAATPPLEQQMQYQPPPQQQQQQLHVSDLAANYDDTHEATVLIEHFKRGDLARHGLHKGYAPVPKYESALPNPDIVRRVEAAIGLRSSTESPERSSSPESDSLLMADRNVMTLPLRKRKHYMNKGDSGQVELEKPQGPSGEVSSAGVDASMDTLDSSGSKVMRMSSVIQFAKAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00481689;
90% Identity: iTF_00477484;
80% Identity: -