Dana006930.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila ananassae
Gene Symbol
-
Assembly
GCA_017639315.1
Location
CM029943.1:27476948-27478882[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.00024 0.018 15.4 5.0 2 23 141 162 140 162 0.98
2 9 5.3e-07 4.1e-05 23.7 3.1 1 23 168 190 168 190 0.99
3 9 3.5e-07 2.7e-05 24.3 1.0 1 23 196 218 196 218 0.99
4 9 1e-05 0.00077 19.7 3.3 1 23 279 301 279 301 0.99
5 9 9e-07 6.9e-05 23.0 0.9 1 23 307 329 307 329 0.98
6 9 2.9e-06 0.00022 21.4 5.6 1 23 335 357 335 357 0.99
7 9 4.1e-06 0.00032 20.9 1.0 3 23 486 506 484 506 0.98
8 9 5.5e-06 0.00042 20.5 0.5 1 23 512 534 512 534 0.99
9 9 1e-07 7.9e-06 26.0 2.2 1 23 540 562 540 562 0.98

Sequence Information

Coding Sequence
ATGCATCTGAACCATGCGACCGCCGCCACAGCAGCCATGGCCTCCTACCAGCAATACCCGCTGCCAGCGAACCATGGCGGGGGTGGTGGAAACGGCGGCGGAGGAGGCAGTGGGGGTGGGGGTGGCGGCAGCGGCAGTGGTGGGGGCGCTGGCCTGCACCAACCAACCACGCTGGCTAGCTTGCAGCAGAGCCCGTTCGCCCTGCACCAACTAACTGCCGTGCAGGCCATCCAGCATCCCACCCACCAGGCCATGCTCCATCCACAACATCCGCTCGTCCACCTGCTGGACATTTCCACAACCACAACGAATAGTGGCGGCGGCGGAGGCAGCCACACACCCATATCGCCGATGAAGCAGGAGGTGCAGAGTGTGATCAGCGAGGAGGAGGTGGTGGTTGATGACCCTCGCAAGAAGAAGCAGTGCCACGTGTGCAAGAACAAGTTCCGGCAGCTGACCACCTTACGCAACCATATGAAGATCCACACAGACGAAAGACCCTACAAGTGCAAGCACTGCGACAAGGCCTTCCGCCAGATCTCGACGCTGACCAATCACGTGAAGATCCATACCGGCGAGAAACCCTTCACCTGCAACATCTGTGCCAAGGATTTCCGCCAACAGAGCACGCTGATCAATCACATCAAGACGCACAAGGCGGCGGAGTCCAGCACGCCCACCTCCCTGCTGAACTACCAGCCGCAGCCGAGCGGCAAGCACCGAAAGTCGCAGATGCATCAGGCGTATCAGCCGCAGCATCAGCGAGTCCAAATCTCAAAGACGTTGTACTCCGGCAGCTACAGTTCTCCGGCGGCGGAGGAGTTGGTGAAGCCCTACCAGTGCAGCGTCTGCAAGCGCCGCTTTCCACAGCTGAGCACGCTGCACAACCACGAGCGGACCCACATCGATCCCAAGCCCTACAAGTGCGAGACGTGCGACAAGTCCTTCAGCCAGCTGGCCACGCTGGCCAACCACAAGAAGATCCACACGGGCGACAAGCCGTACACGTGTTCCTACTGCCACATGCAGTTCCGCCAGCAGAGCACTCTCACCAACCACCTCAAGACGCATACGCACCAGCTCGCCCACGGCGGGGCTGGCGCCGGTGGAGGAGGTGGTGGTGGAGGCGCCGTAACAGCCACAGTGGATCACTCAATGCCCGCTCCTCTGGCGCCCGGAACGCAACAACTGACGAGCGGACTGTTGCCGAATAACCTGCATGGCAGCACGCCAAACATCATCCAGCTGGACCATCATCCGCTGCTGCACTTCCTCGACGGCAGCACCACGGTTAGCTCAGTGGTGGCTACAGCAGCGGCCGCGGCCAATACTAAAGTGGAACCGTTCCAGGGCAGCGGCGGCAGTGGTGGCGGCGGGGGATCACCGCCGGGCCGGATGACCGTGGTGGGCACGATACACATGCTGAAGGGCGATAATCCAGACCGGCCGTTCGGCTGCAGCGTCTGCCAGCGATTCTTCTCGCAGCAGAGCACTCTGGTAAATCACATCAAGACGCACACGGGCGAGAAGCCGTACAAGTGCAAGATCTGCGAGGTCAACTTCCGGCAGGTGGCTACGCTCAACAACCACATGAAGATCCATACCGGGGAAAAGCCCTACAACTGTTCCTACTGCCCCAAACAGTTCCGGCAGAAGAGTACGCTGCAGAACCATCTCAGGGTGCACACCTGCTAA
Protein Sequence
MHLNHATAATAAMASYQQYPLPANHGGGGGNGGGGGSGGGGGGSGSGGGAGLHQPTTLASLQQSPFALHQLTAVQAIQHPTHQAMLHPQHPLVHLLDISTTTTNSGGGGGSHTPISPMKQEVQSVISEEEVVVDDPRKKKQCHVCKNKFRQLTTLRNHMKIHTDERPYKCKHCDKAFRQISTLTNHVKIHTGEKPFTCNICAKDFRQQSTLINHIKTHKAAESSTPTSLLNYQPQPSGKHRKSQMHQAYQPQHQRVQISKTLYSGSYSSPAAEELVKPYQCSVCKRRFPQLSTLHNHERTHIDPKPYKCETCDKSFSQLATLANHKKIHTGDKPYTCSYCHMQFRQQSTLTNHLKTHTHQLAHGGAGAGGGGGGGGAVTATVDHSMPAPLAPGTQQLTSGLLPNNLHGSTPNIIQLDHHPLLHFLDGSTTVSSVVATAAAAANTKVEPFQGSGGSGGGGGSPPGRMTVVGTIHMLKGDNPDRPFGCSVCQRFFSQQSTLVNHIKTHTGEKPYKCKICEVNFRQVATLNNHMKIHTGEKPYNCSYCPKQFRQKSTLQNHLRVHTC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00504822;
90% Identity
iTF_00565509;
80% Identity
-