Basic Information

Insect: Drosophila ananassae
Gene Symbol: -
Assembly: GCA_017639315.1
Location: CM029944.1:15039964-15041753[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00015 0.011 16.0 0.2 3 23 234 254 232 254 0.98

2 12 7.6e-05 0.0058 16.9 1.1 3 23 267 287 265 287 0.96

3 12 3.6e-06 0.00028 21.1 1.8 1 23 293 315 293 315 0.99

4 12 1.5e-05 0.0011 19.2 0.5 3 23 323 343 321 343 0.96

5 12 1.1e-05 0.00083 19.6 0.2 1 23 349 371 349 371 0.98

6 12 5.5e-07 4.2e-05 23.7 0.7 1 23 377 399 377 399 0.99

7 12 3.2e-08 2.4e-06 27.6 3.2 1 23 405 427 405 427 0.99

8 12 1.2e-06 9.2e-05 22.6 7.6 1 23 433 455 433 455 0.99

9 12 2.1e-05 0.0016 18.7 0.3 1 23 461 483 461 483 0.98

10 12 6.5e-07 5e-05 23.4 1.3 1 23 491 513 491 513 0.98

11 12 0.0012 0.095 13.1 3.8 1 23 522 544 522 544 0.99

12 12 0.00013 0.0098 16.2 2.4 1 23 549 571 549 571 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00015	0.011	16.0	0.2	3	23	234	254	232	254	0.98
2	12	7.6e-05	0.0058	16.9	1.1	3	23	267	287	265	287	0.96
3	12	3.6e-06	0.00028	21.1	1.8	1	23	293	315	293	315	0.99
4	12	1.5e-05	0.0011	19.2	0.5	3	23	323	343	321	343	0.96
5	12	1.1e-05	0.00083	19.6	0.2	1	23	349	371	349	371	0.98
6	12	5.5e-07	4.2e-05	23.7	0.7	1	23	377	399	377	399	0.99
7	12	3.2e-08	2.4e-06	27.6	3.2	1	23	405	427	405	427	0.99
8	12	1.2e-06	9.2e-05	22.6	7.6	1	23	433	455	433	455	0.99
9	12	2.1e-05	0.0016	18.7	0.3	1	23	461	483	461	483	0.98
10	12	6.5e-07	5e-05	23.4	1.3	1	23	491	513	491	513	0.98
11	12	0.0012	0.095	13.1	3.8	1	23	522	544	522	544	0.99
12	12	0.00013	0.0098	16.2	2.4	1	23	549	571	549	571	0.97

Sequence Information

Coding Sequence: ATGCGGAAAACACCGGACGCCGGCATGGTCAAGTACTGTCGCTTATGCGCCGTGCCCTCCTCGATACTGGTGGACCTGTTCTCCAAAGATATCTCCAATCCGCCGGTCTCCGAAATGATGAACTCGTTTTTAAAAGAGGATTGCCGCGTAAAAAAGGATGCACTGCCTCAAAAGGTTTGTCCCACATGTTTGGTGGCCGCACAAAGCGCCTTCCAATTCAAGGAGAAGTGCGAGCTGAGTTTCCAATACTTCACACAATTAACCGCGACTGGCAACAAGGAGGACCAGAAAGCGGAACTGGAGCCCGGAGAAATTGCCTTCGAGATGGTTGGATGTGGGGATCCCCTGAGCACCGAGGTTGTGCTGGAGTCTGGAGAGGACAGACTGGACGATTCCGAAACAAAAGTGTGCCCCGTTGAGCTAGAATGCTGCCTTGAAGGGGAGGAGGACACTTTGTTATGTGAAATCACCCCCAGTGATCTGAAGGTAGACGTAAAACTGAAGGCTACGGGGGAAGAATCGCAAAATGGAATAGACCAGCGAGATGGATGTCGATCGGATGAGGACAATGAAGAGGATGGTTTCTCCGATGCCTGGGCCCCCGAGGAGACGTCATCGATATCCAGCGAGGAGGTGGAGGATGATATCAAGATCGAGATCCCACCGAACACCAAGGACGGTAAATCTGCTTCTCTTCTATGTCCCGATTGCGGAGCCCAGTCCACAACACGAAGGGGTCTGGCCAAGCATATGCAGCGACACAAGAATCAGGGCAAGAATCCGGGGCTCCCGCATTTGTGTGATCTTTGCGGGACAGGGTTTAGGACAAATGCCAAACTTGTCATCCATTATCGCCGTCACACGGGCGAGCGACCCTTCAAATGCGAGCTCTGCCCCAAAGCGTACACCCATCGTCCCACCCTCAAGATGCATATGCTCACCCATGATGCGGATAAGGCTCAAAATTGTCCGGAGTGCCAGAAGACTTTCTATAAGGTTTCTGCTTTGCGATCACATATGCTGTTGCACTCGGGAGACCGGCCCTTCAAATGCCCCGACTGCCCGATGGCTTTTAGCAAGAACGCCGGACTTAAGATGCACAGCCGCCTGCATACTGGGGAGCGACCGTACAAGTGCGAGATCTGTGGCCAAGGATTTATTCAAAACCAACATTTGGTCACCCATTTGCGGGTCCACAACGAGGACCGTCCGTTCAAGTGCCCCGACTGCGATAAGTCCTTCTTCGAGAAGTCCAACATGAAGAAGCATCAACGCACCCACTCCGGAGTTAAACCCTACAAATGTGAAGAGTGTGGTCACGAATTCTCGCACGCTCATCATCTTAAGAATCATATGCGGGTCCACACCGGAGAGAAACCGTATAAATGCACTCAGTGTGAAAAATCCTTTGCCGCTAGCCAGTCCCTGGTGAAGCACATCCTTTGGCACGAGGGCAACCGCGTACGTGAGTTCATGTGCCCGGAGTGCCCGAAAGGTTTCGACACAAATCACGGCCTAAAAAGCCACCAAAAGACGCACAAAACGGCGCAACCAAAGCAGACATACCAATGCACGCACTGTGAAGTGAGGTTTGCTTTGAAAAAGACCTACGACAAACATATGTCCACTCATAAGATTCGACCACACCCGTGTCCGCACTGCCCGGAGGGATTCTTCTCCCTGAAGAGCTACAAAAAGCACGTCAGAGTGCACAACCTGAAGAGGGGAACATCTTAA
Protein Sequence: MRKTPDAGMVKYCRLCAVPSSILVDLFSKDISNPPVSEMMNSFLKEDCRVKKDALPQKVCPTCLVAAQSAFQFKEKCELSFQYFTQLTATGNKEDQKAELEPGEIAFEMVGCGDPLSTEVVLESGEDRLDDSETKVCPVELECCLEGEEDTLLCEITPSDLKVDVKLKATGEESQNGIDQRDGCRSDEDNEEDGFSDAWAPEETSSISSEEVEDDIKIEIPPNTKDGKSASLLCPDCGAQSTTRRGLAKHMQRHKNQGKNPGLPHLCDLCGTGFRTNAKLVIHYRRHTGERPFKCELCPKAYTHRPTLKMHMLTHDADKAQNCPECQKTFYKVSALRSHMLLHSGDRPFKCPDCPMAFSKNAGLKMHSRLHTGERPYKCEICGQGFIQNQHLVTHLRVHNEDRPFKCPDCDKSFFEKSNMKKHQRTHSGVKPYKCEECGHEFSHAHHLKNHMRVHTGEKPYKCTQCEKSFAASQSLVKHILWHEGNRVREFMCPECPKGFDTNHGLKSHQKTHKTAQPKQTYQCTHCEVRFALKKTYDKHMSTHKIRPHPCPHCPEGFFSLKSYKKHVRVHNLKRGTS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00481664;
90% Identity: iTF_00481664;
80% Identity: -