Dana005059.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila ananassae
Gene Symbol
-
Assembly
GCA_017639315.1
Location
CM029943.1:12220419-12222540[+]

Transcription Factor Domain

TF Family
THAP
Domain
THAP domain
PFAM
PF05485
TF Group
Zinc-Coordinating Group
Description
The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion. It features the conserved C2CH architecture (consensus sequence: Cys - 2-4 residues - Cys - 35-50 residues - Cys - 2 residues - His). Other universal features include the location of the domain at the N-termini of proteins, its size of about 90 residues, a C-terminal AVPTIF box and several other conserved residues. Orthologues of the human THAP domain have been identified in other vertebrates and probably worms and flies, but not in other eukaryotes or any prokaryotes [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 8.3e-20 2.3e-16 60.2 0.6 1 86 3 93 3 94 0.85
2 2 3.8 1.1e+04 -2.8 2.7 49 61 585 599 533 622 0.54

Sequence Information

Coding Sequence
ATGAAATGCGTGGTGCCCAATTGCAGAAATGCTTTTGTAGGTAGGGCCAAGCGGGACCCAGAACAGCATCAGCAGCCTATTGGTTTCTTCAGTTTCCCCAAGTGCCCGGAAACATTCAAACTTTGGCTTGCCTTCTGCGGTTACGAAAATGCACCCAAAATTAAGAATCCCTACATTTGTATCGAGCATTTCAAGCAGGAGGACATAGAGGGATCTCTCAAGTTCGAAATGGGACTTGCTAAAAAACGAACTTTACGGCCTGGTGCAGTGCCTTGCATCAAAAAAGGTGACAAGAGTGCCTCTGAAGAAGCACGCCTAGAGGGAATACAACGCCGCGAGAACAAGCGCCTGGTGGACGAACTCCTGGCGGAGGACGAGGCGAAGGGCTATACACCCGGCAAGGTGGAGCCAACGCCCAACTACGTAAGATACACCACAGGAATCGCTTCTGCTCCCGACTTTGTTACGCCACCGCAAGATGACGATGACCTGTTCGAGGATGCCTTTCCGGAGTACGATCCCCTGACGTACCAGGAAAAGATTAGGTGCCGCATCTGCTACCAGGATTTGATGAAAGACTCCTCAGCAAAAGATCTCTTCGATGAGGACAACAGCATCCTGCTTTTTCACATAGAAGTCATCAGCGGTGTCTGGATTAGCCAAATCGAAGGAGAACCTCACATTATTTGCCAAACATGTCAGTCGTCACTCCACGAGGCCATTGAATTCCGAGAAATGTGCGTAAACACGGAACTGAGGATAACTCAAGCACTACCCGAAATCGAAGTTACGGCAATCGAGTCTGAGGATGAAGAATCACTACCACTAGAGTCTGACTTTATCCCAGGCGTGGAAGATCAAGCTAATGATCAGGAGGAGCCTCATAAACCCGAAGTCACAACCGATATTCAGCCAAAAGAAGAGCCCAAAGAAGAAGTTACAGACGTTGCTTCACAAGATCCGCTTAGTGTAACTCCCGGAGCCAGGATTTTCAAGGATCTGATCGACCAATACACTGGGCTGGAGAAAACGAGAAACAGAACAAAAACTGGAGATTCCTCGGAAAGAAAACCAAAACCTCCGGCCAAACCTCGAAAAATGCAAGTCCGTCAACAGATAACAAGAAGAAGGGCCAATCCAAAGACCAAGGAGGAGAGAAATCTGATACGTCGCGCCCAACTTCGCGCCAAGCCGCCTAATTTTGTGTGTGATCAGTGCGGCCAGGCCTTCCGCATGTCGCACAACCTGCGGATCCATCAACTGCGCCACACCCGCACCAAGAACTATCAGTGCCCCGAGTGTCCGATGGCATTCTATGATGCCTACATGCGCAATATGCATGTCCGGGTCCGCCATCGAGGAGAAACTCCATATTCGTGCCGTCACTGCACAGAAACCTTCGCCTATGCGGGAGCTCGCCAAAAACACGAGAGCGAAGTCCACGGAGCTCCGCCCCGGACAATTGTGCAGCGCATTAACCCGATGCCCATGCCACGCAACGATGGGAGGCACTTCTGTAAGCTGTGTCACAAAAGCTACGCCTCACAATACGCCCTGCGTTGGCACTCAAAAACGCACACGGATGGCCAAATTTACAAATGCGGGCAGTGCGACAAGAGTTACAATGATCCTGCTAAGCTGAAACGCCATGAGATGTCTCACGAGAAGAGGCCTCTGCAATGCGATGTCTGCCTCAAGGGATTCTACCAGCGAACGCGGCTAAAGGAGCACGAACTTATTCACACCGGCGAGCGACCATACTGGTGTGAGATCTGCAATGTAAACTTCCGGTACAAGTACAACATGAAGACCCACGCCAACACCAAAATGCACAAGGACAATCTGCATAAAAAGAGGTCTATTAATGAATTCGTCGTTGAATAA
Protein Sequence
MKCVVPNCRNAFVGRAKRDPEQHQQPIGFFSFPKCPETFKLWLAFCGYENAPKIKNPYICIEHFKQEDIEGSLKFEMGLAKKRTLRPGAVPCIKKGDKSASEEARLEGIQRRENKRLVDELLAEDEAKGYTPGKVEPTPNYVRYTTGIASAPDFVTPPQDDDDLFEDAFPEYDPLTYQEKIRCRICYQDLMKDSSAKDLFDEDNSILLFHIEVISGVWISQIEGEPHIICQTCQSSLHEAIEFREMCVNTELRITQALPEIEVTAIESEDEESLPLESDFIPGVEDQANDQEEPHKPEVTTDIQPKEEPKEEVTDVASQDPLSVTPGARIFKDLIDQYTGLEKTRNRTKTGDSSERKPKPPAKPRKMQVRQQITRRRANPKTKEERNLIRRAQLRAKPPNFVCDQCGQAFRMSHNLRIHQLRHTRTKNYQCPECPMAFYDAYMRNMHVRVRHRGETPYSCRHCTETFAYAGARQKHESEVHGAPPRTIVQRINPMPMPRNDGRHFCKLCHKSYASQYALRWHSKTHTDGQIYKCGQCDKSYNDPAKLKRHEMSHEKRPLQCDVCLKGFYQRTRLKEHELIHTGERPYWCEICNVNFRYKYNMKTHANTKMHKDNLHKKRSINEFVVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00477549;
90% Identity
iTF_00477549;
80% Identity
iTF_00476143;