Basic Information

Insect: Drosophila americana
Gene Symbol: pita
Assembly: GCA_018152915.1
Location: JAECXQ010000416.1:19334613-19336824[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0053 0.31 11.3 0.2 1 23 261 283 261 283 0.87

2 9 1.8e-06 0.0001 22.2 2.0 1 23 289 311 289 311 0.94

3 9 9.9e-07 5.8e-05 23.0 2.7 1 23 317 339 317 339 0.99

4 9 0.00049 0.029 14.6 0.4 1 23 345 367 345 367 0.96

5 9 0.00019 0.011 15.8 0.1 1 23 373 395 373 395 0.95

6 9 4.2e-05 0.0024 17.9 0.3 1 23 401 423 401 423 0.94

7 9 0.0037 0.22 11.8 5.7 1 23 429 451 429 451 0.98

8 9 1.4 80 3.7 0.0 2 23 487 508 486 508 0.93

9 9 0.0063 0.37 11.1 0.8 1 23 514 537 514 537 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0053	0.31	11.3	0.2	1	23	261	283	261	283	0.87
2	9	1.8e-06	0.0001	22.2	2.0	1	23	289	311	289	311	0.94
3	9	9.9e-07	5.8e-05	23.0	2.7	1	23	317	339	317	339	0.99
4	9	0.00049	0.029	14.6	0.4	1	23	345	367	345	367	0.96
5	9	0.00019	0.011	15.8	0.1	1	23	373	395	373	395	0.95
6	9	4.2e-05	0.0024	17.9	0.3	1	23	401	423	401	423	0.94
7	9	0.0037	0.22	11.8	5.7	1	23	429	451	429	451	0.98
8	9	1.4	80	3.7	0.0	2	23	487	508	486	508	0.93
9	9	0.0063	0.37	11.1	0.8	1	23	514	537	514	537	0.91

Sequence Information

Coding Sequence: ATGAATGCGCACAGCGTTGCCACTCTTGTCGCTGCGTTGCCAGAGCGCATGCACAGTGTCCAGAGCAATGATGGAATGCCCAGCTTTATCTGCCTGGACTGTCGTCTGCTCTTCGAGCACTGTTACCGTTTTAAACAGATGTGTAAAAATGCGGAGACTCTACTCCGCCAATATCCGCTTACTGGCAAATGGCCAGAGCCGCTGGAGAAGCCGCGTGCCCCGCTGGTGGCTAATCAAACGGTTGCAGTCAAGAAGGAACATGCCGAAGCGCAGCCCAAAAAACTGCTCAATTCCATGGCCAAGTCCAACAATGTGCAAATTGAAAGCGTACAGGTATTGGAAACTAGTTCGCTGACCAAAAAGCTACTCAATACGGGTGCAGTGAGCTCTGCTGAGCCGCCGATTCCGCCAAGGGGATCTCCCGCAAAACGCCAACCCTCAAAGTCATATCAGATGAAAGTGGAGAACAACCAGGAACTATCCATGGACGATGTACAAAATTTGTTAGCCGATATGGCTGAAGAACTGGATGATATGGACAACATAACGCCAGCACCTGTAACGACGCCTTCGGCTGGCAAACCAAAAGTACTTAACAAATCGTCGATGCGACTGCTTAACAAAGGTGCCAGCACCACCGTGGAACCACGCCTAGCCACGCCTCAGATCAAGCACTACGAGGACGGAAATGTGGCGCTGGTTACGGAAATACTTGACCCCGATGCAGTTGATGCGTCCGCGGATCCAATTAAAAATGCCGCGCCCGTGGCGACTAACGTCTTTCCGTGTCCACATTGCGATCGCTCATTTCCGCTGATGCAGCTGCTCGACATACATGTTGTGAATCACACACGTACGCGCAGCTTTCAGTGTCCGGAGTGCGACAAGAGCTTCTTCTCCAAGTACGATCTGCAGAAGCACAACTTTATACACACGGGCGAGCGTCCCTACAAGTGCAGTGTCTGCGAGAAGGCCTTCACGCGTCGCGCCCTGCTGCATCGCCACGAGCGAACTCACACGGATGTGCCCAAGTTTATTTGCCTTTACTGCGAGAAGCCGTTTATTTCGCGCAAGGAGATGGAAAAGCATGCCGAACGCCATACCAAAAAGCGGCCTTTCCAGTGCGGCGTATGCCAGAAAGCGTTTGCCTTCAAGCAGGGTCTGGAACGTCACGAGGTCATACATAGCACAAATCTACCATTCTCTTGCCAGTACTGCAGCCGGAGCTTTGTGACCGCAGGCAAGTTGGCCCGTCACCTGGTTGCGCACGCCGGCAAGCGCGTCTATCCCTGCAAGTACTGCTCCAAGTCGTATCTGCTGTCACATCATTTATCGCGGCATTTGCGCATGCACAAGCAGGCACCGGCGACCTCGTTCACGTGCAGCATTTGCAAGGATACGCACCAAACTTATGACAGTCTGGTGGATCACTCGGCCATTCATGCGGGCATCTCGCTAGTCTGTCCACTGTGTCAGGCGAGCATCGCTGACTTGGGCAGCCTGGAGCCGCACATGGAGGCGCACAAGAAGAGCGAAAGACACGCGTGCGAGTTTTGTGATTTTATTTTCCTCAGCTCGAGCCAATTGCAGAAACACATCGAAGACGATCATGTGGTGGACATGGTGCCCTATCAGAATGAAAGCGAATATGAGCAGGGAGTCAGCAAAGAGGAGGATGTCGCCGAGGAGTCCGAATTAATGGAGGAATTGCTAGGCGAGGAGTCAGAGTCGCCATCAAATAAATCTGCATCGCCAACTCAAGCAAAAGTACGCAAACTAAATCCGGTTCCTAAATCGGAGGAAAGCGACAAAATCAAACAAGAGTCGAAACCCAAGGTAATTAAAGATGAGCCAGTTTCACCAGAAAATTTAAAAAGAGCCCGAACCTCAAAGTCACCCGCCGCTGCGTCCGTCTCACCGGAAAGCAAACGCCAGACGCGCAGGCAAGATACCAAAGAAAAAACTGAGAAGCCAAGCGATTCTGGTAAAAGATTGACAAAGAAGGTTATTCCAGACCAAGCCAAACCGAGCAGCAAGCCAAGGAACGCTAAGGCCGCCAGTTCTAAGCATCAGAGCACCAAGTAG
Protein Sequence: MNAHSVATLVAALPERMHSVQSNDGMPSFICLDCRLLFEHCYRFKQMCKNAETLLRQYPLTGKWPEPLEKPRAPLVANQTVAVKKEHAEAQPKKLLNSMAKSNNVQIESVQVLETSSLTKKLLNTGAVSSAEPPIPPRGSPAKRQPSKSYQMKVENNQELSMDDVQNLLADMAEELDDMDNITPAPVTTPSAGKPKVLNKSSMRLLNKGASTTVEPRLATPQIKHYEDGNVALVTEILDPDAVDASADPIKNAAPVATNVFPCPHCDRSFPLMQLLDIHVVNHTRTRSFQCPECDKSFFSKYDLQKHNFIHTGERPYKCSVCEKAFTRRALLHRHERTHTDVPKFICLYCEKPFISRKEMEKHAERHTKKRPFQCGVCQKAFAFKQGLERHEVIHSTNLPFSCQYCSRSFVTAGKLARHLVAHAGKRVYPCKYCSKSYLLSHHLSRHLRMHKQAPATSFTCSICKDTHQTYDSLVDHSAIHAGISLVCPLCQASIADLGSLEPHMEAHKKSERHACEFCDFIFLSSSQLQKHIEDDHVVDMVPYQNESEYEQGVSKEEDVAEESELMEELLGEESESPSNKSASPTQAKVRKLNPVPKSEESDKIKQESKPKVIKDEPVSPENLKRARTSKSPAAASVSPESKRQTRRQDTKEKTEKPSDSGKRLTKKVIPDQAKPSSKPRNAKAASSKHQSTK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00479656;
90% Identity: iTF_00563378;
80% Identity: -