Basic Information

Insect: Drosophila americana
Gene Symbol: ZNF639
Assembly: GCA_018152915.1
Location: JAECXQ010000464.1:14178241-14180329[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.013 0.78 10.0 0.4 3 23 297 318 296 318 0.91

2 10 0.00014 0.0083 16.2 0.5 6 23 327 344 327 344 0.99

3 10 8.5e-06 0.0005 20.1 0.3 1 23 350 373 350 373 0.98

4 10 0.00012 0.0068 16.5 0.5 1 23 385 407 385 407 0.98

5 10 0.13 7.3 7.0 1.4 1 15 414 428 414 430 0.81

6 10 1.2e-05 0.0007 19.6 1.8 1 23 432 454 432 454 0.96

7 10 0.093 5.4 7.4 0.5 2 23 463 484 462 484 0.96

8 10 3.6e-05 0.0021 18.1 2.8 2 23 490 512 489 512 0.95

9 10 1.8e-07 1e-05 25.4 0.7 2 23 519 540 518 540 0.97

10 10 0.00018 0.01 15.9 4.4 1 23 546 569 546 569 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.013	0.78	10.0	0.4	3	23	297	318	296	318	0.91
2	10	0.00014	0.0083	16.2	0.5	6	23	327	344	327	344	0.99
3	10	8.5e-06	0.0005	20.1	0.3	1	23	350	373	350	373	0.98
4	10	0.00012	0.0068	16.5	0.5	1	23	385	407	385	407	0.98
5	10	0.13	7.3	7.0	1.4	1	15	414	428	414	430	0.81
6	10	1.2e-05	0.0007	19.6	1.8	1	23	432	454	432	454	0.96
7	10	0.093	5.4	7.4	0.5	2	23	463	484	462	484	0.96
8	10	3.6e-05	0.0021	18.1	2.8	2	23	490	512	489	512	0.95
9	10	1.8e-07	1e-05	25.4	0.7	2	23	519	540	518	540	0.97
10	10	0.00018	0.01	15.9	4.4	1	23	546	569	546	569	0.96

Sequence Information

Coding Sequence: ATGATCTGTCGCTTGTGTTTAAAAAGCATAAACGCAAACAATGCCGTCTACCTGTTCGAAACCAACGACACACTGGCTGAATCCTCGCTACTGAAGATGATTGCCAAGTTTCTGCAGCTTGAGATAATGCCCGATGACAACATCTCGACAAACATTTGCCACGAGTGCTGTGAGCACTTGGAGGATTTTAACAACTTTTGGCAGCTGGTGGAGCAAAAACAAGGAACACTTAAAAAGGAGTTCCTTAATGTGGACGTCGACTGTGTCGCCCTCAAATGGACGGGCATCGATGTGGATGTCAACATTGATGAGCTGCCACTGGTGGCCGATGAGATGGACGAGAAGCCCCTAGATATACACAATCTCAGTCTGCTCGGCAGTGTGCTTGACGTGAACGTGGATAGCGTCGAGGTGCCGCAGCTAACAACTGCCCCAAAACAATCGCAGACTGAACATTTACCGCCGCTGCTGGCTCCCGACCCTACCGACGACGACGACGAGGATGTCGAGGAGAAACCAACAATGCACGACAGCAGCGACAGCGCGCGGAACGCTTCCTCAGATGATGTTGATGATGATGATGATGATGATGATGACGAGGTGCCGCTGGTCAGGCTGCAGCACAAGCTCAAGCCGAAGCGCCAGGCCCGCACCGTTACACGGCGAAACAAGCGAACGCTGACGCTCGCCCAAGAGCTTGATCAGCTGTTGGATGACAGCGAGCGAGCGGGCAGCAGATCGCGACGAAAGAAAACAACAAACAGTGCGCCAACCGATGTTCAGCGTAGCGAACTGCAAGCGGCACTGGAGCGCAAGCCCAAGGGCTGTTCCCGTGCGCAGCTGACCAAACGCTACGAAGAGGCCATCGCCAGCTATATGAGCGCCGACTGTGATCTCTGCGACTTTAGTACCAAGTACCTGTCACAGCTGAAGGTGCATTTCCTGGAAGTGCATCAGCGCGATGCGTATCTCAAGTGCTGCAACAAGGTCTTCAATCGCGCATCCAAGCTAATGGATCACATACGCAAACACATCAATCCCAGTCTATTCACCTGCTCCATTTGCAACAAGTCGCTAAATTCCCAGGACTATCTGGCCACCCATATTGAGACGGTCCACAACAAGGTTGCCCAGATTGGCAAGGTGCTCAAGTATCCCTGTCCCAAGTGCGAGCGCACCTTCAGCAGCGAGCGCCGACTGGGCAATCATCTACTTAAGCACGACACGGATCAGTTGGAGCACCAGTGCCACATATGCCACAAGAGGTGCTCCATACACGAGGATCTGCATCCGCATGTCTGTGATATATGCGGCAAGAAGTTCAAGTTTAAGCCCTCCTTCGAACGGCATTTGCTGGAGCATCAGGGCGTTGTGGCGCCGGCCATGGAGTGCCCCGTATGCGGTGTCTGGCTAAAGAACGAGCATAGCCTGCGACTGCATCGATTTACACACGACAGCACCGATACCGTCTGCCCGCACTGCTCGAAAACGTGCAGCTCCCGTACGGCGCTGCGCGCCCACATTAAATATGCCCACAAGTTGACCACAAATCTGCAGTGCACGTACTGCGAGAAGAGCTTCAAGCAGCAGCGCAATCTGGAGGAGCACATGGCCATACACACCGGCCTGCAGCTATACAATTGCCCGCATTGCCCCAAAGAGTGCCGCAGTCGCTCCAACATGTACGTCCACATCAAGCAGCGGCACGCGGACGAATGGCTGAAGGCGAAAATGGCCCGATCCCACAATCCGCAGTTCAAGCCGCACGCCTAG
Protein Sequence: MICRLCLKSINANNAVYLFETNDTLAESSLLKMIAKFLQLEIMPDDNISTNICHECCEHLEDFNNFWQLVEQKQGTLKKEFLNVDVDCVALKWTGIDVDVNIDELPLVADEMDEKPLDIHNLSLLGSVLDVNVDSVEVPQLTTAPKQSQTEHLPPLLAPDPTDDDDEDVEEKPTMHDSSDSARNASSDDVDDDDDDDDDEVPLVRLQHKLKPKRQARTVTRRNKRTLTLAQELDQLLDDSERAGSRSRRKKTTNSAPTDVQRSELQAALERKPKGCSRAQLTKRYEEAIASYMSADCDLCDFSTKYLSQLKVHFLEVHQRDAYLKCCNKVFNRASKLMDHIRKHINPSLFTCSICNKSLNSQDYLATHIETVHNKVAQIGKVLKYPCPKCERTFSSERRLGNHLLKHDTDQLEHQCHICHKRCSIHEDLHPHVCDICGKKFKFKPSFERHLLEHQGVVAPAMECPVCGVWLKNEHSLRLHRFTHDSTDTVCPHCSKTCSSRTALRAHIKYAHKLTTNLQCTYCEKSFKQQRNLEEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLKAKMARSHNPQFKPHA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610817;
90% Identity: iTF_00531107;
80% Identity: -