Dame005018.1
Basic Information
- Insect
- Drosophila americana
- Gene Symbol
- -
- Assembly
- GCA_018152915.1
- Location
- JAECXQ010000416.1:18587304-18593659[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.00021 0.012 15.7 3.4 1 23 331 353 331 353 0.98 2 10 0.001 0.059 13.6 10.5 1 23 360 382 360 382 0.96 3 10 0.0001 0.0059 16.7 6.5 1 23 388 410 388 410 0.98 4 10 0.00046 0.027 14.6 1.6 1 23 416 438 416 438 0.95 5 10 2.2e-05 0.0013 18.8 0.5 1 23 444 466 444 466 0.97 6 10 1.5e-05 0.00085 19.4 0.1 1 23 472 494 472 494 0.98 7 10 0.00012 0.0072 16.4 2.0 1 23 499 522 499 522 0.97 8 10 0.052 3 8.2 0.3 1 23 528 551 528 551 0.94 9 10 0.00017 0.0097 16.0 0.1 1 23 609 631 609 631 0.98 10 10 0.0044 0.26 11.5 4.9 5 23 726 744 718 744 0.92
Sequence Information
- Coding Sequence
- ATGTGCGCTGCACAGAGCAATCCGCCGCCCTTCGGCTACACTTGGGGTTTTGCAGACAACGGCAATCGTGCCGCAGAATCAGTTTTGGAGATATCGCCAAATATTAACTACACTGTCAGTGGGGAATCGATGCCCTATCTGTTATCCACGGATGGATCATTGGCCGTACAAAAGGATGTTAAAGGTGCACTCAGCAGCAATAAGGGCAATGTCGTTCGGCGCATGTTCGTGGTGAACGATTCCTCATTTGCGCCCGGAACACAAAGAGTAATTACCACAGGCTCCGCATCGACGGTGGTCAAAAAACAGGACTCTGGTCAACAGGTGTTGAGCATAAATTCGCTCGATAAGAACTATCTTTTGGTCGATCAGGCAACAGCGGCAGCAGCTGCGGCTGCAGCAGGTGGAGGTGATCCGGCGTCTGCTGCACATCATCATACATTGACAAATGGCAGCATTGTTGATGCCAAAACTGGACAAACGGTATTGAGCACATCGGGTGCCGCCGCGGCCGCGGCCAAATCGCATTTTAGCTCAATTGGTGCACTGCATCTAACCCAAGAGGAGTGCAATGAGATCTTAATCAAGCGCGCCATTGCAGCCGGCCACGGCCACCATCAGACGCACACACTCACCGCTGGCGACGGAGCACACCACCACCACCACCACCATCATTCGACGGCGCCAGGCGCGACACCAAGTAAGCATCTCAAATCTGTGTTGTGCTCGAATATCTCCTCCTTCTCCTCCTACAACTCTCCTCTACTGTTCTACTGTTCTACTGTTCTACTGCTACTGCTACTGCTACACTCTGGCCTCTGGCACTGGTATTCGAAAGTAATACAAGGACTCGAAGAGAACGAGGACTCGCAGGGCGACGCACCCAACTTAAAGTTGGAGCCAGGCACATTAGAATTGTCCCCAAAGACCGAACTACAGGAATCAATGCATTTCAGCGAAACCGACGCCACCATCAAAAAGGAGCGCCCGTACAGTTGTGACGAGTGCGGCAAATCCTTTCTGCTCAAACATCATTTGACAACACACGCACGCGTGCACACAGGTGGCGAACGTCCACACATTTGCACCCATTGCGGCAAAAGTTTTGCGCACAAACATTGTCTAAATACGCATCTACTGCTCCATTCGACGGATCGGCCATATCAGTGTCAGGAGTGCAAGAAGAGCTTTACGCTTAAGCATCATCTGTTGACGCATTCGCGTGTCCATAGCCGGGAGCGGCCATTTGTGTGCCAGGAGTGCGGACGTGCATTTCCCCTCAAGCGTCATCTGGTCACGCACAGTAAATTTCACGCCGGCGAACGTCCCTACGTCTGCGAGGAATGCGGTGAGAGTTTCGCACAGGAGAATCACCTGATTATGCACTCGCGCTTTCATGGTTCATTGAATCCATTTGTTTGTGCTGATTGCGGTGCCTCGTTTCCACGCAAATTTCAATTGGTTAATCACGGACGCATACACGGCAAGATACCACACTCCTGCACAGTTTGCGGCAAAGAATTTCTACAGAAGCGCACCCTAGTTTCCCACATGAGGCGCGTACACACCGGCGAGCAGGCGCATCCCTGCGTCAGCTGCGGCGAAGGTTTCCTCACCAAGGCGGAACTGCATCAGCATGTCCGTGCGGCGCACAACGGCGTCAATCCCAATACGAGCAGCGCCACCATTATAGCCAATCAACAGATACAGCAGCCGCATCATCATCCAGGGCATCCGCAGACGATCACCGTTGTCAGCAATCCGGCTAATTCAACGCTGCTCACCGTCTCCACAACCGATGCCAATGGCGTTGCACGTCCACAATTTGTTTGCCGCGAATGCGGCAGCGCGTTTAACAGCCGGGAGGCGCTTGCCTTGCACTTGCGACTGCACACGGGCGACAAGAGCCTTATGACCGATCTGTGCGCTTTGACAGCAGCGCTGCCCGGCCACTTTTTGAGCACGGCGAGCCTCAATCCGGGCACTGTTGTAACGGCCAATCCGAATCTGGTGGGCCAGAGTCCGGTGCCGGTGCAAATCATATCATCCACCGGTCAGGTGATGTCGCAGACCACGCTGGTGCAGGCCGCCAATTCGACCCATCCGCAAGCGGTTGTCACAGCCCACAATCGACGACATCCAAACGGCGGCTGCACGGTGCGCACCCATGTCTGCGAGTGTGGAAAGGCATTCTTCCAAAAGAACCATCTGATGCTGCATCAGCGCCAGCATTTGGAAACAAAGCCAGCCATATCGCAGCAACAGGTATGCTAA
- Protein Sequence
- MCAAQSNPPPFGYTWGFADNGNRAAESVLEISPNINYTVSGESMPYLLSTDGSLAVQKDVKGALSSNKGNVVRRMFVVNDSSFAPGTQRVITTGSASTVVKKQDSGQQVLSINSLDKNYLLVDQATAAAAAAAAGGGDPASAAHHHTLTNGSIVDAKTGQTVLSTSGAAAAAAKSHFSSIGALHLTQEECNEILIKRAIAAGHGHHQTHTLTAGDGAHHHHHHHHSTAPGATPSKHLKSVLCSNISSFSSYNSPLLFYCSTVLLLLLLLHSGLWHWYSKVIQGLEENEDSQGDAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGGERPHICTHCGKSFAHKHCLNTHLLLHSTDRPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCADCGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRAAHNGVNPNTSSATIIANQQIQQPHHHPGHPQTITVVSNPANSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNLVGQSPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQVC
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01556276;
- 90% Identity
- -
- 80% Identity
- -