Dame012941.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila americana
Gene Symbol
-
Assembly
GCA_018152915.1
Location
JAECXQ010000444.1:30126734-30128978[+]

Transcription Factor Domain

TF Family
THAP
Domain
THAP domain
PFAM
PF05485
TF Group
Zinc-Coordinating Group
Description
The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion. It features the conserved C2CH architecture (consensus sequence: Cys - 2-4 residues - Cys - 35-50 residues - Cys - 2 residues - His). Other universal features include the location of the domain at the N-termini of proteins, its size of about 90 residues, a C-terminal AVPTIF box and several other conserved residues. Orthologues of the human THAP domain have been identified in other vertebrates and probably worms and flies, but not in other eukaryotes or any prokaryotes [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 2.5e-21 3.7e-18 65.8 4.8 1 87 3 92 3 92 0.84
2 3 10 1.4e+04 -3.5 3.8 30 71 555 591 483 600 0.62
3 3 10 1.4e+04 -3.7 0.6 50 62 626 640 609 656 0.53

Sequence Information

Coding Sequence
ATGAAGTGTGCGGTGCAAAACTGCGCCAACAAGTTCAAGTCAAGACAAAAACACTCGCAGCAGTTGAGTTTCTTTAGCTTCCCCAAAAACCCGGAAATTTTAAAAAAATGGGTCTCGTTTTGTCGCAAATACAACAAAGAGAAACTTAAGGCTCCTCTGAAGAGTGTCATTTGCAATGAGCACTTCAAGGAGGAGGATATCCAAGGAGCATTACAATTTCAAATGGGCCTGTGCTCAAAGAGAACGCTGAGACCAGGAGCCGTGCCTTGCATCAACAAAAACGATGAAAGCGCAGTTGAACGAGAGCGATCCGAAAAGCGAAAGAACAAGAAATTGGTCGCCGAGCTGTTGGAGGAAGCGGCTGCGCGAGAAGCAGCTGAGGCCAGCGGAGCAATTGTCATAGCTCCAGACTTCATTCGAAATACTGGCATTGTCTCTGTGCCCGACTTTGTGAGTGCCACGGGCAACGCCTTCATTCCATTTACACCGACGCCCAGTGAGAGCGATCCTTTGGCCGAGGAAAGGGCGGAGCTAGATTTGTGCACAAAAGGTAGCTGCAATAATGAAAGACTAACTGATCAGATAAGGTGTCGCACCTGCTGTAGACTCTTTGTTGTCGATGAAAATACTAAGGATCTTTGCGATGAACAAAATGCCGTCATGTTATATCACATTGAAGTTATAACCGGCATTTGGGTCCAATGCAAGGAGGGCATGTCACCGTTCATGTGCTCCGGATGCGTCAATAATCTGCGCACAGCCATTGATTTTCGGGAAACATGTATCCGGGCAGAACTGCAGCTTACCGGGGGCGACGTTGATGAGTTTCCGTCTGTTATTAAAGAAAACGGCAAAGAAATGTCAAATGCACAAGATGCAGAGCTAGTGCAGATTTGTGAGAATGATGCAAAAGATGACTTTGTTTCGGTATTTCCGGCGGAAGATCAAGCTGGTCAAACGACTGTAATTGAGCCTTTATCCCTTGCAGCGGGACAGCAAGTGAATCTGTCAATACGTCCATCGGCTGCAGATCCAAGTAGTATTGCATTGGGTGCACAGATTTATGAGGATCTTCTGAATGAATATAGGGGCAAGGATAAGCTGCCTCGTCCGCGACAAAGAAAGGCAACGACCCAAAGGCCAAACGCGGCAAGAAATCGAAAACGAAAACCTCGGGAGCCAAAACCGAAACGTCCCAAACGCACAAAAGAGGAAAAAAATCGCATACGTCGTGAACAGATCAGAGCCATGCCTCTAAATCATGTGTGCGATCAGTGCGGCGCCTCTTTTCGAGTGAGATGTAATCTAACGATACACATGCTGCGTCATACGCGAACGAAAAACTACCCGTGCTCCGAGTGCCCCAAGAAATTTTACGATGCCTATATGCGAAATATTCACATACGGGTGAGGCACAGGGGAGAGCTGCCATTTGAATGCAATTATTGTCGAAAAGCATTTGGTTCATCTAATACGCGTTATCTGCACGAAAAAAAGGTTCATGGAGCATCTCCACGTATTCACAGGAATGTGAATCGCTTGAACAAAAGAATTGAATTGTCAGATGAGCAACAGGAGCAACAGCCGCCGAATGAGCAGGACCAAAAGGAAATTGTACGGCACTTTTGTTCGTATTGTGACAAAAGCTATGCGACCAAATATGCACTCAATTGGCATAACAATCTGCACATCGGGGCCAAGCCTTTCAAATGCAAATTCTGCGACATGAGCTTTGCAGATCCCCAATCGAAAAAGAAGCACGAAATGAAGCACGATAGCAAACGTCCGTTTGAGTGCGACATTTGTCTGAAGGGCTTCTATGTACGCAGCAAGCTAAAGGAACATGAACGTATTCACACTGGTGAACGTCCCTATAGATGTGACGTCTGCAACGCTTTCTTTCGATATAAATTCAATTTATATTCGCATCAGTTCAGCAAAATGCATAAGGAAAACCTGCAAAAGCTGACAAAGATTGAAATCGTCGATGATTCAAATTAA
Protein Sequence
MKCAVQNCANKFKSRQKHSQQLSFFSFPKNPEILKKWVSFCRKYNKEKLKAPLKSVICNEHFKEEDIQGALQFQMGLCSKRTLRPGAVPCINKNDESAVERERSEKRKNKKLVAELLEEAAAREAAEASGAIVIAPDFIRNTGIVSVPDFVSATGNAFIPFTPTPSESDPLAEERAELDLCTKGSCNNERLTDQIRCRTCCRLFVVDENTKDLCDEQNAVMLYHIEVITGIWVQCKEGMSPFMCSGCVNNLRTAIDFRETCIRAELQLTGGDVDEFPSVIKENGKEMSNAQDAELVQICENDAKDDFVSVFPAEDQAGQTTVIEPLSLAAGQQVNLSIRPSAADPSSIALGAQIYEDLLNEYRGKDKLPRPRQRKATTQRPNAARNRKRKPREPKPKRPKRTKEEKNRIRREQIRAMPLNHVCDQCGASFRVRCNLTIHMLRHTRTKNYPCSECPKKFYDAYMRNIHIRVRHRGELPFECNYCRKAFGSSNTRYLHEKKVHGASPRIHRNVNRLNKRIELSDEQQEQQPPNEQDQKEIVRHFCSYCDKSYATKYALNWHNNLHIGAKPFKCKFCDMSFADPQSKKKHEMKHDSKRPFECDICLKGFYVRSKLKEHERIHTGERPYRCDVCNAFFRYKFNLYSHQFSKMHKENLQKLTKIEIVDDSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00506143;
90% Identity
iTF_00617156;
80% Identity
iTF_00475467;