Damb006628.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila ambigua
Gene Symbol
L
Assembly
GCA_018150905.1
Location
JAECWS010000001.1:4226923-4233827[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.1e-05 0.00076 19.6 3.1 1 23 160 182 160 182 0.98
2 16 0.32 21 5.6 6.2 1 23 188 210 188 210 0.97
3 16 1.5e-07 1e-05 25.5 3.2 1 23 216 238 216 238 0.99
4 16 1.1e-05 0.00076 19.6 0.4 1 23 244 266 244 266 0.99
5 16 0.0034 0.23 11.7 0.2 2 23 395 417 394 417 0.95
6 16 0.056 3.8 7.9 0.7 1 23 502 524 502 524 0.97
7 16 0.0041 0.28 11.5 0.1 2 23 532 553 531 553 0.91
8 16 0.0012 0.084 13.1 0.1 1 23 561 585 561 585 0.92
9 16 1.2 79 3.8 0.9 2 23 621 643 620 643 0.95
10 16 0.0023 0.15 12.3 1.1 1 23 696 719 696 719 0.97
11 16 0.0045 0.3 11.4 1.2 2 23 915 937 914 937 0.96
12 16 0.1 7 7.1 0.1 1 23 943 965 943 965 0.92
13 16 5 3.4e+02 1.8 0.4 2 23 973 994 973 994 0.92
14 16 0.67 45 4.6 0.5 2 23 1094 1115 1094 1115 0.94
15 16 0.064 4.3 7.8 0.0 1 23 1125 1147 1125 1147 0.96
16 16 6e-05 0.004 17.3 1.0 1 23 1154 1176 1154 1176 0.97

Sequence Information

Coding Sequence
ATGATGGCCCTAAAAATGCTTTATCGCGGCCCCAGTTCGCGCTTGGAGAACCTCATCGAGAAGATCCAGGCCACCAAGGAGATCACCAATAACGACATGTACAGTACCCACACCTCGTCCAGCTACTCGCCGAGCATCTCCGATGGCACCATGACACCCAACGCCCATCACCTGGCCGCTGCCTCGGCGAACGCCCTGCAGGAGGACCTCAATCCGGCTGACGGCAAGTCGAACGGCCTCCCAGGAGAGGAGCCAGCGAAGCCGAAGCGCCAGCCGCACTTCCACCACCACCACCATCACTACCACCACCAGCAGGCCCTGAAGATTGCCAACAAGCTGCGCAAAATCAATAAGGAGGCCAAAATGGCAGCTGCCGGAGCTGCAGGACCTGGAGCCGGATCCGGCGCTGCTGGCGGAGCAGCCGCAAAGTTTGATAAGTTGACAGGCGAAGGCATTAAGAGTCGCGGCGACGGCTCCTATCAGTGCCAGTTCTGTGATAAGACGTTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGAGCCATGCCGAGCATCTGCCCTTCAAGTGCGAGTACTGCGCCAAGCTGTTCAAGCACAAGCGCTCCCGGGACCGCCACAAGAAGCTGCACACCAACGAGCGCAACTACAAGTGTCCGCACTGCGAGGCGGCCTTCTCCCGAAGCGATCACCTGAAGATCCACATGAAGACGCACGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAACAGGGGCTACAACACGGCCGCGGCCCTCACCTCGCACATGCAGAAGCACAAGAAGAACGCCGCCATACTGGCTGCCGGCGGCAATCCCAATGCCCTCAACTACAGTCCGCGGTCGACGGGCTCCGCCTCGGCGTCGGTGTCCAGCAATGGGAGCCTGCACAAGCGGCGCTATGCCCTGGCCCTGGCCACCGACAGCAGTTCCAGTCGCCTGGACTTTCCCAAGCGATCGCGCAGCAGCCATGTGGCCAGCACGCCAACACCCACCCCGCTGCTGCGGTGCAGCTACTGCCCCAAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCGAAGACCCCCGTCCAGGAGGGGGAGGGCTTCCAGCTGAGCTGCGAGTACTGCACCATGAAGTTCGGCAACATTGCCGGACTCTTCCAGCACATGCGCGCCACCCATCTGGACCGGCTGAGCAGCCCCAACTCCTACTACGAGCACTTCAACCGGCTGGCCACCGCTGGCACGTTTAGTCCCCGGCTGGCGCTGGATATGCCCAAGATTAAGTCGGATCTGGGCAGTCCCGAGCCGAGGGAGAGCCGACCGCCCGAGGACGACCTGCCCACGGATCTGAGCAGCAACAGGCGTCGCCCGCAGACACCGCCCAGCGCAGCGCCCCATCCCCCGCCGCAGGCAGCGGCCCCACCCGGCATCTTCTTCTGCAACCAGTGCAACGCGGGACTGCCCGACTTCGAGAGCTTCCGCAACCACCTGAAGAGCCACATTGCCGAGGGCATGCAGCTGATCTGCCCGCACTGCGGGCTGAGTCTGCCGGAGCAGTCGGACTTCGAGCGGCACGTGGTGGGCCACTTCCTGATCGCCAGCGCCGAGTTCAACTGCAGCGCCAGCTGCGGCAAGAGCTTCGGCAAGGCGGAGGAGCTGCAGCAGCACCTCAGCGCCGAGCACGTGCTCACCCTGCTGAAGTGCGCCCTCTGCGCGGAGATGTGCGAGACGCGGATGGCCATGCAGCTGCATCTGGCCTGCGCCCACAGCCACGAGACGAAGCTGCTGCGCTGCAGCGCCTGCATGGAGGTCTTCCGCTCCGACGGCGACTTCCACGTGCACGTCAAGACGCGCCATCAGCTGGGCAACCACCACCAGCAGCACCACCAGCAGCACCACCCGCTGGGCGGCAGCGGCAGTAGTCCGGCCAACCCGCTGCAGTGCATGTTCTGCCGCGCCGTGTGCTCCTCCGAGCTGGAGATGCACTTCCATCTGGCGGCGCATGCGCGACAGTTCCGCTGCCCCTCCTGCCCGGAGACCTTCCACGTGGAGTTCCTGCTCGACAGGCACATGCAGAGCCAGCACGGCGGCGGCAAGGACAAGGAGCAGCCGCCCCAAAGCTCCCCCAACATGGGCAGTCTCTATGTGAACGCCCTGCTGCCGCCCCTGGCCGCAGCGGCCGCTGCCGCCGCCGCCACCAACAACAACAGCAGCATCATCGACTACAACGTGGCCTTCAAGGGGCTGTTCGGGGGGGGAGCCGGCGCCGGGACCGGAGGCAGTGCACCCACGGGCCCCGCGGCGGCCAGCAAGTTCTACAGCCCCTTGCAGGTGGACACGAATGCCTTGAAGGCGCAGACCTCGCCCCACCCCGCCTTGATGTACGGCCTCAGCCAGCGGTACCTCATGGAGATGTACGCCGCCAAGTCCACGTCTCCGGCCAACAGCACCGCCAACGAATCAGCAGCAGCAGCAGCAGGAGGGGGAGGGGGAGGAGTAGGAGGAGCCTCCTCCATCAATGGCCCGCCAGCAGCGCAGGCGCCGCCGCCGCCAAGCGCACCCGCCGCCACCTTCAGCTGTGGGATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCGGAGCTGCACTCGCACCGGAAGCTGGCCCACAACCTGAAGACTGGCGTGAGCCTGCGCTGCGCCTACTGTGCGGGCAACTTCAAGTCGCGGGCGGAGCTGGAGCAGCACATGAAGAGCTGCCACAACTCGACGGGCAAGCACAAGTGCCTGATCTGCGACGAGATCTTCCCCTCGCCGGCCATCCTGGCGGAGCACAAGCTGCAGCACTCGAAGGTGGGCCAGTCGGGCAAGTGCGCCCACTGCAGCCACCCGCTGGAGGATGTGGCCGCCTTCCGGGCCCACCTCGGCGAGCATGGCAGCGACGGCGGCTCCCTGCCCCTGGCCTGCATCTGCTGTCGCCAGACGCTCCACTCGGAGTTCGAGCTGAGCCTGCACGCCAAGTTCCACACCAAGTCCTCGTCCAGTGGCGGCAGTCTCCAGGAGCCGGTTTGCGCCCTCTGCCTGCAGCCGCTGCCCGGGGCAGTGGAGGGTCCCACCACGCCGGCCAAGCTGTGCGAGAAGTGCTGCCGCAAGCACAACCTCAACGGCAAGCGGAGCAAGGCCAGCGAGGGCCCCGCGATCCAGGCCCAGCCGGCTGCCTACCTGGAGAACCGCTGCAACCTGTGCAAGATGATCCTGCCGCACGCCCAGAAGCTGCAGGAGCACCTCGTGGAGCACACCTTCGCCGGCACCGAGCAGCGCGGCTTCAACTGCTACATCTGCTCGGCCGTCTTCACGGCCCCCGGCGGCCTCCTGGGCCACATGGCCGAGCACGGCGCCCACTCGCGTCCCTACGACTGCAACATCTGCCCCGAGAAGTTCTACTTCCGCGCCGAGCTGGAGCACCACCAGCGGGCCCACGAGCTGAGGCCAACGGCCCGGCCAGCGCTGGCCAAGCCAGAGCCACCGATGCGGCAGCGCAGTGCATCGCCCAGTCCGAGTCCAGTGCGCAGTCCCACGACCGTCAAGCAGGAGTTGTACGACACGGACACGGCCCACTCGGGCGGCTGTGAGGATGAGCCAGAGCCCGCCCAGGATGAGGAGGAGTACATAGAGGTGGAGCGCATGCCGCACGAGACGCGGCCAAGGGATGCCATGTCTCAGCTGGAGAGGGCCACAAACAGCGCCTGA
Protein Sequence
MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTMTPNAHHLAAASANALQEDLNPADGKSNGLPGEEPAKPKRQPHFHHHHHHYHHQQALKIANKLRKINKEAKMAAAGAAGPGAGSGAAGGAAAKFDKLTGEGIKSRGDGSYQCQFCDKTFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASASVSSNGSLHKRRYALALATDSSSSRLDFPKRSRSSHVASTPTPTPLLRCSYCPKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKTPVQEGEGFQLSCEYCTMKFGNIAGLFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALDMPKIKSDLGSPEPRESRPPEDDLPTDLSSNRRRPQTPPSAAPHPPPQAAAPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLICPHCGLSLPEQSDFERHVVGHFLIASAEFNCSASCGKSFGKAEELQQHLSAEHVLTLLKCALCAEMCETRMAMQLHLACAHSHETKLLRCSACMEVFRSDGDFHVHVKTRHQLGNHHQQHHQQHHPLGGSGSSPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGKDKEQPPQSSPNMGSLYVNALLPPLAAAAAAAAATNNNSSIIDYNVAFKGLFGGGAGAGTGGSAPTGPAAASKFYSPLQVDTNALKAQTSPHPALMYGLSQRYLMEMYAAKSTSPANSTANESAAAAAGGGGGGVGGASSINGPPAAQAPPPPSAPAATFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCAGNFKSRAELEQHMKSCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCSHPLEDVAAFRAHLGEHGSDGGSLPLACICCRQTLHSEFELSLHAKFHTKSSSSGGSLQEPVCALCLQPLPGAVEGPTTPAKLCEKCCRKHNLNGKRSKASEGPAIQAQPAAYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLGHMAEHGAHSRPYDCNICPEKFYFRAELEHHQRAHELRPTARPALAKPEPPMRQRSASPSPSPVRSPTTVKQELYDTDTAHSGGCEDEPEPAQDEEEYIEVERMPHETRPRDAMSQLERATNSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
iTF_00611560;
80% Identity
-