Basic Information

Insect: Drosophila ambigua
Gene Symbol: -
Assembly: GCA_018150905.1
Location: JAECWS010000100.1:4028622-4035046[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.033 2.2 8.7 1.8 1 23 865 887 865 888 0.94

2 8 0.0068 0.46 10.8 0.1 1 23 893 916 893 916 0.98

3 8 0.0059 0.4 11.0 2.5 1 23 1079 1102 1079 1102 0.95

4 8 0.00031 0.021 15.0 2.1 1 23 1110 1132 1110 1132 0.98

5 8 3.5e-05 0.0023 18.0 0.8 1 23 1139 1162 1139 1162 0.97

6 8 3.7e-05 0.0025 17.9 1.4 1 23 1168 1190 1168 1190 0.96

7 8 4.2e-06 0.00028 20.9 0.9 1 23 1195 1217 1195 1217 0.99

8 8 0.013 0.86 10.0 3.0 1 23 1223 1245 1223 1245 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.033	2.2	8.7	1.8	1	23	865	887	865	888	0.94
2	8	0.0068	0.46	10.8	0.1	1	23	893	916	893	916	0.98
3	8	0.0059	0.4	11.0	2.5	1	23	1079	1102	1079	1102	0.95
4	8	0.00031	0.021	15.0	2.1	1	23	1110	1132	1110	1132	0.98
5	8	3.5e-05	0.0023	18.0	0.8	1	23	1139	1162	1139	1162	0.97
6	8	3.7e-05	0.0025	17.9	1.4	1	23	1168	1190	1168	1190	0.96
7	8	4.2e-06	0.00028	20.9	0.9	1	23	1195	1217	1195	1217	0.99
8	8	0.013	0.86	10.0	3.0	1	23	1223	1245	1223	1245	0.99

Sequence Information

Coding Sequence: ATGAGCCTCGTCAGCCGCGACGATGGACTTCCGCAGGAGATTTGCCGCCAGTGCATGGCCCAGTTCCTGATGGTGGCCAAATTTCGAAGGAAATGTGTGCGGATGCAGCAGCGCTTGCAGGACTATGCCCAGGAAATATCCGACCGGCAGGCAGCCAGACAGGCCAAGCGAAAACAGAAGCAGCAACTGCTGGAGGAGACGCAGACCACACGACGAGAGGAACAGGATGCGAGGAATACCAATACCAATACGGATGCGAATGCGAGTACATCGGACTACATGCATTTGCCCGAATCACAGATGGAACGAAAGCGTCGCATTATCTCTGAATCCGAGGGTGAAGCCCCATCCCCTCTGCCGCCACTGCCAAAACTTGTGAAGACGGAGGAGGCCGCCACGGAGGAGGTTCTGCCACCGCCCAAGGCACGTCGCCTGCAGCTGAGATTGCGCAGAATGCGAACACAGTCCGTAGGAACTCCGGAACCGGCTGCGAATGCGACTGGGAATGCGGAGGAACGAGCCCCTGCCCACGCTGATCCCAGCAGCATGCCGTGGAAGACAAAGGCTGCGCGGAAGCAGCTGTCCGAGTCGTGGTCCAGCTACTCGCCGGCTCCCTCTTCGGAGATGGAGGGCCGAAGGAGTACCAGCAGTGAGGCGGCCACAGAACATCTGAGCGATCTGTCGGTGGGGCCACTCTGTGGCTTCGAGAGCGACAGCAATCCCTCCTCCACCTCAGCGCCATCGGAGCTCAAGTTCCCCAGGCGATCGCCCAAAGCGATGGCAGCACTGCGACGTGCCCGTCGTCCGCGGAGTTCGCCCGTTTACATGGCAGCCAAGCGGCAGCGGCGATCACTGAGCAAGAAGCCGACGGTGAAGGAGCTCATCCAGCAGATTGGAGCTGAATCCAGTCTGGAGGAGAACACAAAGTCTGACGGGGAAATCTCCTGCGAAAAGCCAAAGGAAAAGCAGTACGAATCAGATGAGAACTGTCCAACTCCGCTGCGTCCAGTGGCAACGTCTTCCTCCTGCGATGAGGCAAGCGACATCAGTACTTCAGATGCGGAGGTGGCAGGAGAATCATCCATCGATGAGGTCCCAAAGGAAATCCAAGAATTAAAAGAAGTCCCAACGGATGGCAAGGAGTCCCCAAAGGAATTGGAAACCAACTGCGATGAGAAACCAGAGGCAGAGTCGGTCAAAGAGCTGACGTCCAGGACAGAGAAGTCACCGAGTGATTCGTCGGATGGGAGCACCTTACGAAATGAGGAGGAGGAGACTCCGTCCAAGCAAAAGATTGAGGGTGTAGAAGAACAAACATTGAAAGGAGCAGCCGCCACTGTCGATCTATCATCGATGGAGCTACAGTCCAAGGAACTGACCTCGTCCACGGAGGCCACAGTCACAACCACAACCCTTGAGGGGGAACAGGTGTCTGTGGAAGGAGCAGAACAGCCAGAGCAGCCCGAGCAGCCAGAGATCATCGTGAGCATACCCCTCGAGGCACTCAATGAGGATCTGCAGCGCAGATTGTGCGTGGACAACACTGGAGAGCAGCAGGAGGAGGATCAGGATCAGGAGAAGAAGCAGCAGCTTCCAGGCCATCCCGACGATGTCAACAACAATGCAAACGATGAGAATTTTTGCCAGAGTGCTACAGCAGATAGCTTCAATTCTGCTGTGGCACTCCAAACAAACGAAATTGAAGCCCCCGATAGGTCCACTGATGCAGAGCCACTGTCACACGTGGCAGAGTCCCCACCACCACCACCACCACCGGATGGGGACGACGAGGACTCCTTCTCGTCTACGGATGAGAGTGAGATCCAAGTGGTAAGGACTGGACCCACACCCATGGACTTTCTGGCCGAATTCGAGAAGCATTGCGAGAAGGGTCTCGAGCAGATTGGAGCCACCACACCCGCCCCATCGCCGCCACCCACACCCAGAGCCGAGCCCCTGCCGCTGGCCCTCAACGATCTGGAGGCCAAGCAGCAGCTCGAGGTGGAGATGAACGATGTGGAGACCACACTGAATGGCATCCTCAACGAGATGCAGGACCAGCACATGTACACGCCGACCTGTCCGCACATCGATGAGTTCCTCACCCCCGCCGACTATGCATCCCTCAGCGAACCCGAGCAGGAGCAGGAACAGGAGCCGGAGCCAGTCGGCGACGCCAAGCCAGATCTCGCCGAGTCGCAGGAGAAACCCAACCCGGGGGCCAGTCAGCGGGAGGAACTCTTCGACAACAGCAACTTTAGCAACGAGCTGATTGGCTTCCAGAATGATATTCCCTGCTTCGAAAACATCGAGGCCTCGCCAGAGCCCGAGCAGAGTCTGCATCTGGAGTTGACGCAGTTCCTCAACGAACTGCAGCCACAGCAGGCAGTGCAGGGATCGCAGGTATCGCCAGGGGTATTGCCAGTCCAAGTGCAAGTGCAGGTGGCGGTACCGCAGGTTGAGGCAGTGGCCGTCCCCCCCGAGGGTCGCGCTGTCTCGCTCAAGTGCCGCTTCTGCCAGAACGGACCGAGATTCAACAACAGTCTGGAGTACAGTCGTCACATCATCGAACTGCATCCGGCGGTGGCGCCATTCAACTGTCCGCACTGTCCTCTGGCCTTTGCGGCGCGCAGCAAGCGGTCGCAGCACATCCTCAACCATCATGTGGTGCAGCAGTACCAGTGCGGGCAGTGCTCGCAGGTGTTTCCCGCCCAGCGAGCCCTCGACCTGCACATCCAGCGCTTCCACATGCAGATTGCCAGCAAAAAGGGCGGCAGAGAAAAGGGAGGAGCTCTGGAGCTGCATGGACACACCACGCCAGGACCACGCAGGCAACGCATTCTCTGCTGTCCGGACTGCGAGGACTGTACCTCTGGCCACAGTCACGGCCACGGACAGTACGAGGAGCTGCAGACCAATCTGCAGGCGCCGCCAACGGTGCTAACGCCGCCATCGACGATCATGTCGGTGCCGTCCCCGCAGCCCATGATGCACATAACCCTGCCCTCGCCGGAGCAATCGGAGCCGGACTCCACCACGACGCTGCGGCAGTTCCGCAAGCGAGGCGTCATTGTGGCTCCGCAATCGGGGGGCTTTAATCAGTCGCTGCAGCTGGCCACGCCCGTGGCATCGCCCTCACCCTCGCCCTCGTCGTCGCCGTCCTCTTCCACGATAGACTCGGCGCCAAACACGCCCGCCTCCGCCAACGTGCAGGTCAGCGAACTGCGGACCAGCCACCAGTGCATGTACTGCGAGGAGCGGTTCTCCAACGACATTGCCCTGCGGAAGCACCACCAGCTGGCCCACGGAGCCCAGACCTCGATGCCCTTCGTATGCACCATCTGCAAGCGGGGCTATCGGATGCGCACGGCCCTACATCGGCACATGGAGTCGCACGACGTGGAGGGACGGCCGTACGAGTGCAATCTGTGCCATGTGCGGTTCCCACGACCCTCGCAGCTGACGCTGCACAAGATCACCGTCCACCTGCTGTCCAAGCCGCACACCTGCGACGAGTGTGGCAAACAATTTGGTACGGAGAGCGCCCTAAAGACGCACGTTAAGTTTCACGGTGAGCTTGGTTACCAGTGCGACGAGTGCGATCTGGCATTCGAGTATCTCAGAGATTTACGCAAGCACCGGCGCACCCACAACAGCGAATTGTTTTACAAGTGCGAGTTCTGTCCACGATCCTTCTTGCATTTTATGGGTTTCCGCGCTCACATGAACTCCCATCTGCCACTGGGAGTGTTTCTGAACGAGGAGGTCGCCCTGAAGTCGTCGTCGACCAACTGCAGCACCACCACCACCACCACCACCACCAGCATCAGCATCAGCAGCATCCACAATGACAAGTCCGGCGAGAATCCAGCCACACCCATAATGGAGGATGGGTCATCACCACTGACCCCGATGAGCAATATCAATAGCAATGCAGATGAGTGCTGTCAAATCTCCGATTCGGTGGAGAGCAGTGTTTTGGTTGGGCGTAGCCTACCCAGCCTAGACTCGATTGCCACAACGCCATAA
Protein Sequence: MSLVSRDDGLPQEICRQCMAQFLMVAKFRRKCVRMQQRLQDYAQEISDRQAARQAKRKQKQQLLEETQTTRREEQDARNTNTNTDANASTSDYMHLPESQMERKRRIISESEGEAPSPLPPLPKLVKTEEAATEEVLPPPKARRLQLRLRRMRTQSVGTPEPAANATGNAEERAPAHADPSSMPWKTKAARKQLSESWSSYSPAPSSEMEGRRSTSSEAATEHLSDLSVGPLCGFESDSNPSSTSAPSELKFPRRSPKAMAALRRARRPRSSPVYMAAKRQRRSLSKKPTVKELIQQIGAESSLEENTKSDGEISCEKPKEKQYESDENCPTPLRPVATSSSCDEASDISTSDAEVAGESSIDEVPKEIQELKEVPTDGKESPKELETNCDEKPEAESVKELTSRTEKSPSDSSDGSTLRNEEEETPSKQKIEGVEEQTLKGAAATVDLSSMELQSKELTSSTEATVTTTTLEGEQVSVEGAEQPEQPEQPEIIVSIPLEALNEDLQRRLCVDNTGEQQEEDQDQEKKQQLPGHPDDVNNNANDENFCQSATADSFNSAVALQTNEIEAPDRSTDAEPLSHVAESPPPPPPPDGDDEDSFSSTDESEIQVVRTGPTPMDFLAEFEKHCEKGLEQIGATTPAPSPPPTPRAEPLPLALNDLEAKQQLEVEMNDVETTLNGILNEMQDQHMYTPTCPHIDEFLTPADYASLSEPEQEQEQEPEPVGDAKPDLAESQEKPNPGASQREELFDNSNFSNELIGFQNDIPCFENIEASPEPEQSLHLELTQFLNELQPQQAVQGSQVSPGVLPVQVQVQVAVPQVEAVAVPPEGRAVSLKCRFCQNGPRFNNSLEYSRHIIELHPAVAPFNCPHCPLAFAARSKRSQHILNHHVVQQYQCGQCSQVFPAQRALDLHIQRFHMQIASKKGGREKGGALELHGHTTPGPRRQRILCCPDCEDCTSGHSHGHGQYEELQTNLQAPPTVLTPPSTIMSVPSPQPMMHITLPSPEQSEPDSTTTLRQFRKRGVIVAPQSGGFNQSLQLATPVASPSPSPSSSPSSSTIDSAPNTPASANVQVSELRTSHQCMYCEERFSNDIALRKHHQLAHGAQTSMPFVCTICKRGYRMRTALHRHMESHDVEGRPYECNLCHVRFPRPSQLTLHKITVHLLSKPHTCDECGKQFGTESALKTHVKFHGELGYQCDECDLAFEYLRDLRKHRRTHNSELFYKCEFCPRSFLHFMGFRAHMNSHLPLGVFLNEEVALKSSSTNCSTTTTTTTTSISISSIHNDKSGENPATPIMEDGSSPLTPMSNINSNADECCQISDSVESSVLVGRSLPSLDSIATTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00487573; iTF_00611670;
90% Identity: -
80% Identity: -