Basic Information

Insect: Drosophila ambigua
Gene Symbol: -
Assembly: GCA_018150905.1
Location: JAECWS010000100.1:5282855-5284243[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 2.7e-06 0.00018 21.5 4.6 2 23 252 273 251 273 0.96

2 5 3.2e-05 0.0021 18.2 1.5 1 23 279 302 279 302 0.97

3 5 0.00041 0.027 14.7 2.6 1 23 308 330 308 330 0.97

4 5 2.6e-05 0.0018 18.4 1.8 1 23 336 358 336 358 0.96

5 5 9.4e-05 0.0063 16.7 2.8 1 23 364 388 364 388 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	2.7e-06	0.00018	21.5	4.6	2	23	252	273	251	273	0.96
2	5	3.2e-05	0.0021	18.2	1.5	1	23	279	302	279	302	0.97
3	5	0.00041	0.027	14.7	2.6	1	23	308	330	308	330	0.97
4	5	2.6e-05	0.0018	18.4	1.8	1	23	336	358	336	358	0.96
5	5	9.4e-05	0.0063	16.7	2.8	1	23	364	388	364	388	0.91

Sequence Information

Coding Sequence: ATGACGCTCCAATGCCGAGTCTGCGGGGGCGTCATCTACAACACCAAGGCCAAGAATCTATTCCAGAATGAGAACTCTTCGCTGTTGCTGAACATCGAATTGGTGTGCGGGATTTTGCTCGTGAATGATCCAGAGCTGCCCAGTTGCATCTGTGCTTGTTGCTTGCACGACTTGACTCAGGCAATCGTGTTCCGAAATCTCTGTATCCAGACGCAGGAGAACTTGCGGCAGAATCGCAGCAGAACTCCTTCGGAGCTCGCAACGGACTATGATGAGGACACAGAAATTAAGCAAGAGATTGAAATGGACAGTGAGCTGGCGGCCATGTCGTCTGGTGACCTTGACTATTCCTATGCAAATATGGACGAGCTGTTCGACCCAGACGAGAATGTTGATGACCCACCAAACCATAATAGTGATGAGGGGGAGGACACTGCACATGATGCAGACTCTCTGATTACGAGTCTGAAGAAAGAGCTGGGTAGCATTTATGATAGCAGTGATGACGAAGTCGAGCACGAAGAGCTCGCGGAATTCTCCGAGAACAACAACTCAAGCGGCAGATCCTCTCCAGCCGACAATGTGTCATTGTCACCTGTGTTGGTTATCCAAACCAAGAAAAGAGGCCGACCCAAGAAAATGCCACCTGCAACAACGCCAGCTAGCAAAGCCAAGAAACAATACACGACTTGGAAAAATTTAACAGAGGAAGAGATAATCGAAAGGAAGCGGCAACAGCGTCGTCGGGATTGTGTCTGTGAGCAGTGCGGTAGGCACTTTACCGATCAGAGCAACTTCAAATTGCACATGATCAGGCATACGGGCATCAAGAATTTTGAATGTCAGGATTGTGGGAAAAAGTACTACACAGATCATTTGCTGTCGCTCCACCAAAGGATTGTTCACAGAGGCGAAAAGCCCTATGCCTGTAAATACTGCGACAAAACTTTTCACAACAGCACAACCCGCGTAATACACGAACGAATTCACACAAATGCACGACCGTATGCCTGTAACCATTGCAGTAAAAGTTTTAGCTCGGCATCTGGGCGCAAGCGGCATGAATTAATACACACTGGCGTGAGGGCATTTTACTGCGCCACCTGCGATCAAACTTTCCAGCGCAACACACACTTAAAAGCTCATCTTCAGTCAAAGTTGCATATCATGAGAGCAAAACATAAGGAGATAGATTAA
Protein Sequence: MTLQCRVCGGVIYNTKAKNLFQNENSSLLLNIELVCGILLVNDPELPSCICACCLHDLTQAIVFRNLCIQTQENLRQNRSRTPSELATDYDEDTEIKQEIEMDSELAAMSSGDLDYSYANMDELFDPDENVDDPPNHNSDEGEDTAHDADSLITSLKKELGSIYDSSDDEVEHEELAEFSENNNSSGRSSPADNVSLSPVLVIQTKKRGRPKKMPPATTPASKAKKQYTTWKNLTEEEIIERKRQQRRRDCVCEQCGRHFTDQSNFKLHMIRHTGIKNFECQDCGKKYYTDHLLSLHQRIVHRGEKPYACKYCDKTFHNSTTRVIHERIHTNARPYACNHCSKSFSSASGRKRHELIHTGVRAFYCATCDQTFQRNTHLKAHLQSKLHIMRAKHKEID

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00603612;
90% Identity: iTF_00564203; iTF_00611612;
80% Identity: -