Basic Information

Insect: Drosophila ambigua
Gene Symbol: -
Assembly: GCA_018150905.1
Location: JAECWS010000094.1:2832759-2836017[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.51 34 4.9 0.8 2 23 92 113 91 113 0.92

2 8 0.036 2.4 8.5 0.5 1 23 149 171 149 171 0.97

3 8 0.0068 0.46 10.8 0.4 1 21 177 197 177 198 0.95

4 8 0.079 5.4 7.5 0.1 2 23 569 591 568 591 0.93

5 8 2.6e-05 0.0018 18.4 0.2 1 23 718 740 718 740 0.98

6 8 1.4e-06 9.3e-05 22.4 3.3 1 23 746 768 746 768 0.99

7 8 0.00017 0.011 15.9 2.5 1 23 774 796 774 796 0.98

8 8 0.00065 0.044 14.0 0.1 1 21 802 822 802 823 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.51	34	4.9	0.8	2	23	92	113	91	113	0.92
2	8	0.036	2.4	8.5	0.5	1	23	149	171	149	171	0.97
3	8	0.0068	0.46	10.8	0.4	1	21	177	197	177	198	0.95
4	8	0.079	5.4	7.5	0.1	2	23	569	591	568	591	0.93
5	8	2.6e-05	0.0018	18.4	0.2	1	23	718	740	718	740	0.98
6	8	1.4e-06	9.3e-05	22.4	3.3	1	23	746	768	746	768	0.99
7	8	0.00017	0.011	15.9	2.5	1	23	774	796	774	796	0.98
8	8	0.00065	0.044	14.0	0.1	1	21	802	822	802	823	0.96

Sequence Information

Coding Sequence: ATGCACGTGGATTTGAGCATAATTAAGGAGGAAATCGACATTGATGACACCACGATCAAGCTGGAGGTGGAAGAGAATGCGCCGGAGGAGGCAATGGACGTTTCCTGTGCGAGTGGAGCCGTGAAAATACTTGAGGAGCATGACAATATGATAACGGTACCACTCAGCGATCACAGATCGGAGGACGAGCTCCAGTTTATAGCCAGCCTGGGTACGATGGATGCCCAACAGTTATTCGCAGAATCGTCGAAGAACCAAAATGGCTGTGCATGCGAGTGTCACATTTGCAATATACAGTTACCCACGCAACTGGAGATTAAGGCGCACTTGGTTAACCATCAGATGAACCGTCACTTCTGTCGCTATGGATGCGGTGCCTGGTGCGCCACTCTGGAATTGGTGCTTGAACACGAATATCGACACCATTCCCACGGCATAATGACGTTCTGCTGCAGGATCTGTGATTTAAGGGTTGATGGCGCCGACCGTCTGGCCAGCCATATGAAAAGCCACTCTTATGTGAGTCGCTACGTGTGTGCCATATGCCGACGTCATTTCTACTCTCAGGTGGGCCTGATACTACACCGGAAGAACACCACCTATGTCTGTGGACAGGTGGACTATATTCCGGTAATCTCTGTGACTCCAGAGCACGTGGCAGCCAAGTCGGCTGAATGTGCTGCACCAGTTGATCCGCTACGCATTATGAAGATCAAGAATGAACCACCTGATCCGCTGAGCATTGTGAAGATCAAAGACGAACCACTGGACGTAGATGGGATGGACCCACAGCCACAGAAAGAGGTTGGGCTTGATGTGTACATCAAAGCCGAGCCCTTGGACGAGCCCTTGGAGAAGGTTACTCCCACAAAGGAGCTGCCGGAATCTTCGAGAGTATCAATCTGGGCAAGCCTACCCGTTGAGCTGAGGAGCAAGCTGCGATTGCCTGCCTTGAAGCCCAAGCAAATGATACAAAATAACCCTCGGCCACCCCTCAAATTTGTAAAATTGAATGGGCCGCCAGCATCGAATGCCACTCCTGTTGGTGCGCAGCAGATTTTATTCAAAGTTTTGCCTGACGGCCAAAAAATAAACATTACAGATTTGGTGAGCTTAAAGAAAATCGCAAATTTGAAGACGAATGTGAATGGAAAGCCCCCAATGTCTTCGAATGTACTGAAAGTGTTGCCCAGCAACTGCATGGTCATCAAGTTGCCGCCAAATACAAAAATTGTAAAGCTATCGAATCAGCCGAGTGCACTTGCCCCCCCTGCAAAGGCAAATGGTGTGCCGCTCTCGTCCCCGCAGAACGTAGCTGCTCAGTTGCCAAATTCGCTTACAATTAGAAAGATAACGCCAGAAGAAACCACCTCCCCCGTTACGGCTAGTCCAGTGGATTATAAACCGCTTATTCCCTGTCGGGATCGCAGCTACAGTCTGAAGAATCGGCCAGAATGTTATGAATTGATTACGGAAATTCAAAATCAAATACGCTCCATAGAAAAGACGCTGCCAATGCCGGGGACCGTCTTATTTACAAGAGATGACTTAACAACGACAGTAGTCGCCGAACCAGTAGTGACTACCCCAGTGACTACAACATTACCGGGCGCGCCCTTGGAGGTGGAAATACATCTAGATCCCGAGGCGCATAGGGTGATGCAGGAACTGCGAAAGCAACACCCGGACTTTCGTTTCTTCTGGACTTGTCCCATCTGTGCACGCAACTATGAGCAGGGCTACGCATTCCGCACGCATCTGATACAGGAGCATAAGCAGAAGAGCGCCAACTTGGCGAAGCTGAAAGTTAAATTAAAGCCCCAAATAAAAACGTTATGGACAGAAACGCAGGCGCCACCGAAAGATAATCTAGAATCGGATTCAAGCGCGCCAGAGCCTGCTCCAGCTTCAGAAGTGGGTGATTCAGTCGCGGAAAAAGCAGCAAAGCCTGCAACTCCAACAAAGGAGATACCGGTGCTTACATCTGTCCAGCTGTCGGCCACAGCCCAGTCAGCCGCACGACCGCCAGCCGTTTTGGCGACTCCACTAATCGAAGCAGCATCATCAGAGTCCGAAACAAAGATATCATATACATGCAGGTCCCCAGATGTCCCCGAGACAGCGAAAATAGATGAAACAAAGCCATCGCAGTTCCAGTGCCCCACGTGCCTCAAAATATTCACCACCCAGGGAGGCATGCGAATTCATATGTCAATCCACACGGGTGAAATGCCGTACAAGTGCCATTATTGCGACAAGCGCTTCCGCACTCCTGGCCAAGTGCGTGTCCACGAGCGCCGTCACACTGGGGAGAAACCCTTCCAATGCAAGATCTGCAGCCTGGATTTTACTCATCGAGAGACTCTCATCTCGCACCTATCGCGCCATATTGGAATGAAGCGCTACAAGTGCTACGGCTGTGACAAGTACTTTGTCGTGGTCAGCGGCCTTCGGGCCCATCGTCGCCTGCGGCCGGATACGTGTGGCAAGGTTAAGTTCACGGCTCGAGCCCATGGGCCGCGCGTGCGTGTCATAAAAGGGGAAGTCGTCTTCGAGCCCCAGCCAAGCTACAATGGCTACTTGCGCAGCGAAGATCCGCTCGAGATATTGAAAGAGCGGGGCCAAATCGACTCAATCCCTGCAACCCAAGCCAAGAAGCCGGAAGCTGAAGCTGCGGCTGCGACCGAAGCCGAAGCCAAAGCCAAAGCCTTGGCTGTAGAATAG
Protein Sequence: MHVDLSIIKEEIDIDDTTIKLEVEENAPEEAMDVSCASGAVKILEEHDNMITVPLSDHRSEDELQFIASLGTMDAQQLFAESSKNQNGCACECHICNIQLPTQLEIKAHLVNHQMNRHFCRYGCGAWCATLELVLEHEYRHHSHGIMTFCCRICDLRVDGADRLASHMKSHSYVSRYVCAICRRHFYSQVGLILHRKNTTYVCGQVDYIPVISVTPEHVAAKSAECAAPVDPLRIMKIKNEPPDPLSIVKIKDEPLDVDGMDPQPQKEVGLDVYIKAEPLDEPLEKVTPTKELPESSRVSIWASLPVELRSKLRLPALKPKQMIQNNPRPPLKFVKLNGPPASNATPVGAQQILFKVLPDGQKINITDLVSLKKIANLKTNVNGKPPMSSNVLKVLPSNCMVIKLPPNTKIVKLSNQPSALAPPAKANGVPLSSPQNVAAQLPNSLTIRKITPEETTSPVTASPVDYKPLIPCRDRSYSLKNRPECYELITEIQNQIRSIEKTLPMPGTVLFTRDDLTTTVVAEPVVTTPVTTTLPGAPLEVEIHLDPEAHRVMQELRKQHPDFRFFWTCPICARNYEQGYAFRTHLIQEHKQKSANLAKLKVKLKPQIKTLWTETQAPPKDNLESDSSAPEPAPASEVGDSVAEKAAKPATPTKEIPVLTSVQLSATAQSAARPPAVLATPLIEAASSESETKISYTCRSPDVPETAKIDETKPSQFQCPTCLKIFTTQGGMRIHMSIHTGEMPYKCHYCDKRFRTPGQVRVHERRHTGEKPFQCKICSLDFTHRETLISHLSRHIGMKRYKCYGCDKYFVVVSGLRAHRRLRPDTCGKVKFTARAHGPRVRVIKGEVVFEPQPSYNGYLRSEDPLEILKERGQIDSIPATQAKKPEAEAAAATEAEAKAKALAVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00564187;
90% Identity: iTF_00564187;
80% Identity: -