Basic Information

Insect: Drosophila ambigua
Gene Symbol: -
Assembly: GCA_018150905.1
Location: JAECWS010000002.1:21944014-21945948[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 2.5e-05 0.0017 18.5 1.1 2 23 210 231 209 231 0.96

2 6 2.7e-05 0.0018 18.4 1.3 1 23 237 260 237 260 0.95

3 6 0.00019 0.013 15.7 1.2 1 23 269 292 269 292 0.97

4 6 7.6e-06 0.00051 20.1 0.6 1 20 305 324 305 327 0.93

5 6 0.00051 0.034 14.4 3.2 1 23 335 358 335 358 0.96

6 6 2.5e-05 0.0017 18.5 0.9 2 23 366 388 365 388 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	2.5e-05	0.0017	18.5	1.1	2	23	210	231	209	231	0.96
2	6	2.7e-05	0.0018	18.4	1.3	1	23	237	260	237	260	0.95
3	6	0.00019	0.013	15.7	1.2	1	23	269	292	269	292	0.97
4	6	7.6e-06	0.00051	20.1	0.6	1	20	305	324	305	327	0.93
5	6	0.00051	0.034	14.4	3.2	1	23	335	358	335	358	0.96
6	6	2.5e-05	0.0017	18.5	0.9	2	23	366	388	365	388	0.95

Sequence Information

Coding Sequence: ATGTTTGAATCAAAAGCAAAACATCGCGCGCGTCGTGCAGTTGCGGACTCCACTACTGTCGCAGGAACTGAAACGGAAGCGAGCAAGATGCTGCTATGCCGGGCCTGCCTGGTGCTACTTAGTACCGAGGATGTGTCCTACGACCTATGCAGCGAGAAAGGCTTGGCGACCAAATACTTTGCCTGCACCGGTGGCGACCCGGACATGCACATTCAGATGAAGGAAGAGGAACAACTGGTACCGCAGCAGTTGGTGCTGAAAAGCATCTGTGAATGTTGCTACCAGTTAGTGCAGAAATTCCATGACTTTCAACGCATGTGCGAAGAGTCCTCCAGGAACTTTGAGAAGCTGCTGGCGGTGGTAAACTCTCAGGATACCGTCCATAACTCCATCCAGGAGCAAGATGTAACCAACACCAGCTCCGCTCTGCCAGAATATGATACTCTTTCGGAAGGCATACAATGCGATGGCGAGGAAGCGACACCCGCAGAATCAATCGAAGATATTGAGGAAGTGTACATTATTGAGGATGAAAGTGCAAAGAAAAATCTTGGAAGAGAGAAGATTCCCATATCGTCACGGCAAAATGTGCCCGGGCAACGCAAACAGGGACTGAGATATACGCTTAACTGCAGCAAATGCAATCGGGGATTCTACAAAATCTCATCGCTCGAGGCACATATGAAGAAACACGATGGCATAGATCCTCACCCGTGCGTGCACTGCGGCAGGAGCTACGCAAGAGCAAACCTCCTTGAATCACACCTGCGCGAGAAGCACTTGGGCTCCACTCAGAGTATAACTTATCCGTGTCCCAGGTGCGATAAGGTCTACAGTGCTTCGCGCAGTCTGAACTACCACTTCAAGAGGAAACACAAAAGTCAACAGAAGCAGGAGCCCCCAGCATCTATGCACATGTGCGACAGGTGTGGGAAATCGTATGCGCGAAAGGCGAACCTTGCACGCCACCAATGGGTGCACAGGAGCATGGATGAGCGCCGTCACGTGTGCCAGTTCTGTGGCCAGCGCTTCTACACGAAGCAAAACATGGTGGATCACCTGCAGCGACGGCATACCAGCAGTAAGAGTCTATTGCGGTGCAAGAAATGCGGTCGCATCTTCCGGTCTCGGGCGGCCCTGGCCGTACACCGTACAAAAAAGCATGCGAGTGCCACCACCGGTGGTGCACGGCAGAAACAGGATCGATCCTCAGCTCAGATCGTTAGGGAATAA
Protein Sequence: MFESKAKHRARRAVADSTTVAGTETEASKMLLCRACLVLLSTEDVSYDLCSEKGLATKYFACTGGDPDMHIQMKEEEQLVPQQLVLKSICECCYQLVQKFHDFQRMCEESSRNFEKLLAVVNSQDTVHNSIQEQDVTNTSSALPEYDTLSEGIQCDGEEATPAESIEDIEEVYIIEDESAKKNLGREKIPISSRQNVPGQRKQGLRYTLNCSKCNRGFYKISSLEAHMKKHDGIDPHPCVHCGRSYARANLLESHLREKHLGSTQSITYPCPRCDKVYSASRSLNYHFKRKHKSQQKQEPPASMHMCDRCGKSYARKANLARHQWVHRSMDERRHVCQFCGQRFYTKQNMVDHLQRRHTSSKSLLRCKKCGRIFRSRAALAVHRTKKHASATTGGARQKQDRSSAQIVRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00603574;
90% Identity: iTF_00611568; iTF_00603574; iTF_00564162;
80% Identity: -