Basic Information

Insect: Drosophila ambigua
Gene Symbol: RREB1
Assembly: GCA_018150905.1
Location: JAECWS010000100.1:5001177-5002461[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 8.3e-05 0.0056 16.8 0.4 1 23 158 181 158 181 0.95

2 8 0.0095 0.64 10.4 2.0 1 21 187 207 187 208 0.92

3 8 1 69 4.0 4.7 1 23 222 244 222 244 0.95

4 8 3.2e-06 0.00021 21.3 2.0 1 23 250 272 250 272 0.97

5 8 1.3e-05 0.00091 19.3 2.7 1 23 278 301 278 301 0.92

6 8 8.7e-05 0.0059 16.8 3.3 1 23 307 329 307 329 0.98

7 8 1.7e-05 0.0011 19.0 1.2 1 23 335 357 335 357 0.99

8 8 1.1e-05 0.00077 19.6 3.3 1 23 363 385 363 385 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	8.3e-05	0.0056	16.8	0.4	1	23	158	181	158	181	0.95
2	8	0.0095	0.64	10.4	2.0	1	21	187	207	187	208	0.92
3	8	1	69	4.0	4.7	1	23	222	244	222	244	0.95
4	8	3.2e-06	0.00021	21.3	2.0	1	23	250	272	250	272	0.97
5	8	1.3e-05	0.00091	19.3	2.7	1	23	278	301	278	301	0.92
6	8	8.7e-05	0.0059	16.8	3.3	1	23	307	329	307	329	0.98
7	8	1.7e-05	0.0011	19.0	1.2	1	23	335	357	335	357	0.99
8	8	1.1e-05	0.00077	19.6	3.3	1	23	363	385	363	385	0.98

Sequence Information

Coding Sequence: ATGTCTCTACAATTAAGCGATTTGCTTTGCCGGGTGTGCTTGCAACAAGACGAACTCCTGGTGGACATTTATGAGCATGTGGAAGAGCTTCAATTGGACTTGTGCTCGTTGCTGGAGAGTTGCGGCAACATTAAAGTGAACCCATCCGATGCATATCCGAAATATTTATGCCAGGAGTGCACCAAGGAGCTGCTCATCACGGCCAAGTTTCGCAAAAAGTGCTCCGAGACAGAGATACGACTGCAAGAAGACGCTGCACGCATTTCGCTGATTTACAAGGAGGAAGATATTCTGGCGGATGAAGAAATTGTGGGGGAGGAGGAAATGTGTCTGCCGGAGGAAGGGTACCTGGCAGAGGAAATCATTGTATGCGATCCCAGCGACTATGCGGACCGGATGCCAACAGCGGAGCAGGAGGAGTCGATTGAAGAGGATCAGGCGGATCCGTTGCCGCCACTCGTCTCTGCCAGGTACAACTGCGACAATTGTGGTGCCGTCTTCCAGCAGGCCCAAACCCTACGCAAGCATCTCGAGAACTTCCATGCTCTTATCACCATCTACGACTGCAAAATGTGTGGTCAGTTCTACACGGACCTCGCCACTTACAAAAGCCACAGCTGCACCGATCGCTCCGCGGAATCATCGCCGGACAAAAGCGGTCGGCATAGATGCATCCACTGCGGCAAGTGTATGCAGTCGGCCACCAGTCTGGACGAGCACCTTCGACTGCACAGCGGCGAGCGACCTTATTGTTGCGCCAATTGCCCAAAGACATTTACGACGAATGGAGCCCTGGTCACGCACCAGAAGCGGCACTTTAAAGTAATTCAGCACCACTGCAGCTATTGTGGGCAGGGATTCGTGGAGTCTAGCAATCTCAAGCGCCACATTACCGCCAAGCACACAAAGGAAAAGCCGCACACCTGCACCGTCTGCCAGCGCAAGTTCTCCAGGGTCTATCTGCTGGAGCTGCACAGCCGCACCCATACGGGCGAACGGCCGTATAAGTGCAACCAGTGCCAACGTAGGTTTAGCCAGCTGGGCGTGCTACGCAGCCACGAGAGAATACACTCGAATGAGCGCCTTCATCGCTGCCAGTTCTGCCCGAAAACCTTTGGTCGTGCGACTCAGCTTAGAACTCATCTGATGCGGCACGAAAGCGGTCAAGTTCAGTGA
Protein Sequence: MSLQLSDLLCRVCLQQDELLVDIYEHVEELQLDLCSLLESCGNIKVNPSDAYPKYLCQECTKELLITAKFRKKCSETEIRLQEDAARISLIYKEEDILADEEIVGEEEMCLPEEGYLAEEIIVCDPSDYADRMPTAEQEESIEEDQADPLPPLVSARYNCDNCGAVFQQAQTLRKHLENFHALITIYDCKMCGQFYTDLATYKSHSCTDRSAESSPDKSGRHRCIHCGKCMQSATSLDEHLRLHSGERPYCCANCPKTFTTNGALVTHQKRHFKVIQHHCSYCGQGFVESSNLKRHITAKHTKEKPHTCTVCQRKFSRVYLLELHSRTHTGERPYKCNQCQRRFSQLGVLRSHERIHSNERLHRCQFCPKTFGRATQLRTHLMRHESGQVQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00611564;
90% Identity: iTF_00611564;
80% Identity: -