Basic Information

Insect: Drosophila ambigua
Gene Symbol: -
Assembly: GCA_018150905.1
Location: JAECWS010000094.1:2672775-2674633[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 2.1e-06 0.00014 21.9 1.7 1 23 247 270 247 270 0.97

2 8 6e-06 0.00041 20.4 0.5 3 23 281 301 279 301 0.94

3 8 0.012 0.79 10.1 0.1 1 23 310 333 310 333 0.92

4 8 0.00042 0.029 14.6 0.0 3 23 343 363 341 363 0.97

5 8 6.5e-05 0.0044 17.2 6.4 1 23 369 391 369 391 0.98

6 8 7.5e-05 0.0051 17.0 0.2 1 23 396 418 396 418 0.98

7 8 1.5e-06 0.0001 22.3 1.7 1 23 424 446 424 446 0.97

8 8 0.0089 0.6 10.5 3.8 1 23 452 475 452 475 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	2.1e-06	0.00014	21.9	1.7	1	23	247	270	247	270	0.97
2	8	6e-06	0.00041	20.4	0.5	3	23	281	301	279	301	0.94
3	8	0.012	0.79	10.1	0.1	1	23	310	333	310	333	0.92
4	8	0.00042	0.029	14.6	0.0	3	23	343	363	341	363	0.97
5	8	6.5e-05	0.0044	17.2	6.4	1	23	369	391	369	391	0.98
6	8	7.5e-05	0.0051	17.0	0.2	1	23	396	418	396	418	0.98
7	8	1.5e-06	0.0001	22.3	1.7	1	23	424	446	424	446	0.97
8	8	0.0089	0.6	10.5	3.8	1	23	452	475	452	475	0.97

Sequence Information

Coding Sequence: ATGGCCGCCGCCACGCTGAGTGGCCACGAGGCCAGTGCCTCGGACTGGCGTCTGTGGTGCCGCCTATGTGCCAAGAACGACCTGCAGGGCAACATAAATGTGTTTCTGAAAAACGAGCATACGGGCGGTCCTGGAGATGGCTCAGGCAGCGATCTGGCACTTGCCACAGCTATTGGAAAGTACTTTTGGGTGGATATAACGCGTGGCGAGGAACTGCCAAAGATGATCTGCACCGACTGCCTCACGCTGGTCACAACTTTGGTCAACTTTTCGGAGCGCATTAGTCGCGTGCAGAAGCTCTACTGCATTCTACAGGCCAGCGCCAAGCAGGAGCATGTGAATCTGCAGGAGCTGCGCTCCAAGTTTGGCCTGCTGGAGGAGGAACCAGAGACCCAAACTGAAGTCCACTATGTGGAGGAGAAACCCAAGTTGGGGGCACAAGGCGATCTGCTGATAGAAGAGTCTGCATTCGAAATGAAGAACCCGCTAAATGAGACGGCAGAGGATCAGGAAGAGGAGCATGGAGAAGCAACAAGTAGAAGCGAGGAGAATGAAGACGAATCGGAGCAGGAAGAGCAAGAGCAAGAGCAGCAGGAACTGGAGATGGAGCAGGAGCAGGGGTACGATGAAGATGCAGTGCTGCTGAAGCTCTGCGATGCCTATGGGATTAACGAAGATAGTTCCTCGCGCGACACCCACAAATGCCCTCCAAGACAGAAGGAGAACCCCGACAAGGCACATCAGTGCAGCATGTGCACGCGGGCGTATGCCAGAGCCAGCACCCTGAACCGCCACATGCGGCAGGACCATGATAGGATCTACGAGCCCAATCTGCTGGCCTGCGAGGAGTGTCCCAAGAAGTTTCGCACGCGCTACCAGCTGGAGCGGCACAGCCAGGGCCATCTGCCGATGCCGAAACGCAAGGTCTATCCGTGTGCCAGCTGCGACAAGATGTTTGCCAGCAGCGCCTCCGCCGTGCAGCATGCCCAGTACATGCATTTGGATGAGCGGCCACGGCCCGTCATCTGTGAGCAGTGCGGCGTGCGGGTCACGTCCATCAGCAACCTCAAGGTGCACGTACTCACGCACACGGACGATGCACCCTTCGAGTGTGATGTGTGCAAGAAGTGCTTCAAGAGCGCCAGCCGGCTGAAGCATCACAAGGAGACGCACGATCCGCACAAGTACATCTGTCCCGAGTGTGGCATGCAGCTGAATTCGCGCACCACCCTCAATCGCCATCGCCTCGTGCACACGGATCAGATGCAGCACAAATGCGACTACTGTGGCAGGGAGTTTAAGCGCGCCAAGGCCCTCAAGAATCATCTCATACTGCACACCGGCCTCAAGCCGTACTCCTGTGACTTCTGCGATCGCACATTTGCCAATGGCTCGAATTGTCGCACGCACAAGAAGAAGGCCCATCCCGAGGAGTTGGCCGCCCAGGAGGCGGCTGGCGGTGGCAAGACATGCAATCGGAATATACCCAAATTGGAGGCGCTGAAGGCTTTCACAAAAAACAAGGATAATTTATCGCCCGTGGCCACCAAGCAGAGCGGTTGCTTTGCCTTTGGCAAGAAGCCCAAGCAGCAGATCAAAGAGGATGTAAGTCCGCCTGCAGCGGAGCCAGTGGCCGAAGTCAAACCTCCCACAACAGCAGCAACAACAACGGCCATACCCATACCCACGATAGATACGATTTACAATCATATTATGATTGATTACCATTAA
Protein Sequence: MAAATLSGHEASASDWRLWCRLCAKNDLQGNINVFLKNEHTGGPGDGSGSDLALATAIGKYFWVDITRGEELPKMICTDCLTLVTTLVNFSERISRVQKLYCILQASAKQEHVNLQELRSKFGLLEEEPETQTEVHYVEEKPKLGAQGDLLIEESAFEMKNPLNETAEDQEEEHGEATSRSEENEDESEQEEQEQEQQELEMEQEQGYDEDAVLLKLCDAYGINEDSSSRDTHKCPPRQKENPDKAHQCSMCTRAYARASTLNRHMRQDHDRIYEPNLLACEECPKKFRTRYQLERHSQGHLPMPKRKVYPCASCDKMFASSASAVQHAQYMHLDERPRPVICEQCGVRVTSISNLKVHVLTHTDDAPFECDVCKKCFKSASRLKHHKETHDPHKYICPECGMQLNSRTTLNRHRLVHTDQMQHKCDYCGREFKRAKALKNHLILHTGLKPYSCDFCDRTFANGSNCRTHKKKAHPEELAAQEAAGGGKTCNRNIPKLEALKAFTKNKDNLSPVATKQSGCFAFGKKPKQQIKEDVSPPAAEPVAEVKPPTTAATTTAIPIPTIDTIYNHIMIDYH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575031;
90% Identity: iTF_00603528;
80% Identity: -