Basic Information

Insect: Drosophila ambigua
Gene Symbol: ZNF212
Assembly: GCA_018150905.1
Location: JAECWS010000001.1:5714869-5716747[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 1.7 1.2e+02 3.2 2.9 1 20 99 118 99 119 0.93

2 10 0.002 0.13 12.5 1.1 1 23 159 181 159 181 0.97

3 10 0.031 2.1 8.8 1.1 1 23 207 228 207 228 0.97

4 10 5.4e-05 0.0037 17.4 1.8 1 23 235 257 235 257 0.98

5 10 3.9e-05 0.0026 17.9 0.8 1 23 281 303 281 303 0.98

6 10 2.6e-06 0.00018 21.6 0.4 1 23 309 331 309 331 0.97

7 10 7.4e-06 0.0005 20.1 2.2 1 23 337 359 337 359 0.98

8 10 6.2e-06 0.00042 20.4 1.2 1 23 365 387 365 387 0.98

9 10 3.6e-06 0.00024 21.1 0.4 1 23 391 413 391 413 0.98

10 10 0.0011 0.077 13.3 1.2 2 23 444 466 443 466 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	1.7	1.2e+02	3.2	2.9	1	20	99	118	99	119	0.93
2	10	0.002	0.13	12.5	1.1	1	23	159	181	159	181	0.97
3	10	0.031	2.1	8.8	1.1	1	23	207	228	207	228	0.97
4	10	5.4e-05	0.0037	17.4	1.8	1	23	235	257	235	257	0.98
5	10	3.9e-05	0.0026	17.9	0.8	1	23	281	303	281	303	0.98
6	10	2.6e-06	0.00018	21.6	0.4	1	23	309	331	309	331	0.97
7	10	7.4e-06	0.0005	20.1	2.2	1	23	337	359	337	359	0.98
8	10	6.2e-06	0.00042	20.4	1.2	1	23	365	387	365	387	0.98
9	10	3.6e-06	0.00024	21.1	0.4	1	23	391	413	391	413	0.98
10	10	0.0011	0.077	13.3	1.2	2	23	444	466	443	466	0.94

Sequence Information

Coding Sequence: ATGTCGTCCGCCATCAAGCGTGGTAAACCAGCTACCGATACCTCCATGCACGTGGACGTCAAAAAAGTCCAGGAGTCCGTGCTATATTGCAATGTTTGTAGAAATTTGTACGAGAACGAAGAGGCATACGAGGAGGACCATCATAGTGGCACCTGCCTCAGCGGCAGGGAATGCATAGACGAGATGGATTTGGTCGAGCAGGAGGAAATAGTGGAAGCAGATGTGCCGCTCTGGGACGTAATAGATGACGTTGACGATGCAGCACCACAGCCAGTCGATGCAGAGTCGGAACGTTACTTTTGCTTTGATTGCCACATCATATACGACAGCCACAGCAGTGCCGAAAACCATGTGTGTCCACCAGAAGGGGCTAGCAAAGGAGCCAGCCAAAGGTCGACCATGCCCAAGCAACCCGTCCGGCGCAAAGCTCTTGGCGCCGGAGCAGCGGCAGACATCAACGGAGATAGCCCCAAATTTATTTGCAAAATTTGCAATACCATTTTCGCCTCGGAAAAGAGTCTCAAGTTCCACAAGCGCATACACGACGAGCGCAAGCCCAAGCGAATCAAGGATGCCCTTCCTGTGGGCGCCCATCAGGAATATAGCGAACTGGATCTGTTCTACTGCGAGATCTGTCAAAGAGAGTTCGATTACGGCCTCAAGACGATTCACCAGAAGATGCACGTAGAGGCCCCCAACAAGTTTGTGTGCGGCACTTGCAATCGCCAGTTTGAAACCTCCACCAACTACCGGATGCATTTGAAGATGCATGAGAAGAAACAAGCGGAGCCTACTGCTTCATTGTCGAAAAAAGGGCCCGTCGACAAGAGTAAAGCACAATTTCCATGCCAGTACTGCGATAAGGTATTCTACCGGCCATTCGAGAAGGTCAAACACGAACGTGTGCACACAGGAGAGAAGCCCTACGCCTGCGAGGCTTGCGGCAAAACATTTCGCGTCTCATACTCTCTCACCCTGCATCTGCGCTCCCACACAGACATTCGCCCCTACGTGTGCACTGTCTGCAATAAGCGCTTTAAATTGCAGTCAAATTACGCTCATCACCTCCTCATCCATGGCGCGGAGCGTCAGTTTTCCTGTGATATATGCTCCAAGTCCTTCCGCACATCTGTGCAGTTGAACGGCCATAAGAATTCGCACACCAAGCCATTCGAGTGTGAGATTTGCAATCGGCCCTTCTCCACGATGTATGGCGTCAACAATCACATGAAGACCCACAAGCACGGCAAAGGCAGCAAAAGTACAACCGTGATTGTTTCGGCTGAAAAGGAGGACGACTCTGTCAAGATTCTAGCTGGTGGCAAGTGCTCCTGCAGTGAGTGCGGGGCAGAGTACTCGCGCATGTATGCGCTGCGGCAGCACTTTAAGTCGGCTCACGGCAAGGTATCGGGCGCTAAAGCAAACAAGAATGAGCAATCTACCAATGTGGCCGAGTCGGACGACTCTGAGGCAGCCATACGCAAAGCAGCAGCAGAGGCAGATGCTGCGTACATGCATGCGGTGGTGAACGATGTGGATGTCAGTGGTAGCGTGCCCACCTACCAGGAGGCTGTTGAGGTAAGTACAGCTTTCGATGTGGACGACTTCAACGGCGAGGAAATAATCAGTGATTGGCTGAAATAG
Protein Sequence: MSSAIKRGKPATDTSMHVDVKKVQESVLYCNVCRNLYENEEAYEEDHHSGTCLSGRECIDEMDLVEQEEIVEADVPLWDVIDDVDDAAPQPVDAESERYFCFDCHIIYDSHSSAENHVCPPEGASKGASQRSTMPKQPVRRKALGAGAAADINGDSPKFICKICNTIFASEKSLKFHKRIHDERKPKRIKDALPVGAHQEYSELDLFYCEICQREFDYGLKTIHQKMHVEAPNKFVCGTCNRQFETSTNYRMHLKMHEKKQAEPTASLSKKGPVDKSKAQFPCQYCDKVFYRPFEKVKHERVHTGEKPYACEACGKTFRVSYSLTLHLRSHTDIRPYVCTVCNKRFKLQSNYAHHLLIHGAERQFSCDICSKSFRTSVQLNGHKNSHTKPFECEICNRPFSTMYGVNNHMKTHKHGKGSKSTTVIVSAEKEDDSVKILAGGKCSCSECGAEYSRMYALRQHFKSAHGKVSGAKANKNEQSTNVAESDDSEAAIRKAAAEADAAYMHAVVNDVDVSGSVPTYQEAVEVSTAFDVDDFNGEEIISDWLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00601212;
90% Identity: iTF_00564107;
80% Identity: -