Damb008050.1
Basic Information
- Insect
- Drosophila ambigua
- Gene Symbol
- -
- Assembly
- GCA_018150905.1
- Location
- JAECWS010000107.1:4322775-4328912[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 1.6e-05 0.0011 19.1 2.1 1 23 215 237 215 237 0.97 2 18 5.2e-06 0.00035 20.6 0.4 1 23 243 265 243 265 0.97 3 18 0.00076 0.051 13.8 0.9 1 23 271 293 271 293 0.95 4 18 1.1e-05 0.00074 19.6 3.1 1 23 299 321 299 321 0.97 5 18 2.5e-05 0.0017 18.5 4.7 1 23 327 349 327 349 0.99 6 18 4.5e-05 0.0031 17.7 5.7 1 23 355 377 355 377 0.97 7 18 2.2e-07 1.5e-05 24.9 4.3 1 23 383 405 383 405 0.98 8 18 8e-08 5.4e-06 26.3 2.4 1 23 411 433 411 433 0.97 9 18 4.7e-05 0.0031 17.6 6.7 1 23 440 462 440 462 0.97 10 18 8.1e-05 0.0055 16.9 6.5 1 23 468 490 468 490 0.98 11 18 7.2e-06 0.00049 20.2 4.5 1 23 496 518 496 518 0.98 12 18 5.2e-06 0.00035 20.6 8.1 1 23 524 546 524 546 0.98 13 18 4.3e-06 0.00029 20.9 7.6 1 23 552 574 552 574 0.97 14 18 4.8e-07 3.2e-05 23.9 7.7 1 23 580 602 580 602 0.98 15 18 0.00015 0.01 16.0 9.5 1 23 608 631 608 631 0.95 16 18 5.3e-05 0.0036 17.5 0.9 1 23 637 659 637 659 0.98 17 18 0.00056 0.038 14.2 4.4 1 23 669 691 669 691 0.98 18 18 6.6e-06 0.00045 20.3 1.6 1 23 697 720 697 720 0.96
Sequence Information
- Coding Sequence
- ATGCAGCACGTGAGCGCTGCGAGCTCGGTGCCATCAGTTGTAGCCCCGGTCGTGACCACTGGTGGAACCACCATCACCCTCGGCGGACCGCCGCCATTGCCTAAATCAGAGAACAAAGAGGATGGCAAACCGCCGCACGGCATAGAAATGTACAAGGTGAACATTGAGGATATCTCCCAGCTGTTTACATACCACGAGGTCTTTGGAAAGATCCATGGCGATGTGGTGAATCATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGGAGGCAACGGCCTGCCGGTGGCGACAAGCTCCGGTGGCCAGCAGGGCAGCGCAACGGTGACCACGACCAGTTCGACGGCGAGCAGTGGCAGCGGCGGCAGCGGTAGCGGGGGCACCACAACCACGGCGGGTGAGTTGCTTATGCCTAAAATGGAGGGCGGCATTCATGGCGTGGACGGGCAGTCGACCGTGGCGCTGGCCCCAGACGGGACGCCCATTGCGACGGGGACCCATGTGTGCGACATTTGTGGCAAGATGTTCCAGTTTCGGTATCAGCTGATCGTGCACCGTCGCTACCACAGCGAACGCAAGCCGTTCATGTGTCAGGTGTGCGGACAGGGTTTCACCACGTCGCAGGACCTGACACGCCATGGCAAAATCCACATCGGTGGCCCCATGTTCACCTGCATCGTGTGCTTCAATGTGTTTGCCAACAACACCAGTCTGGAGCGGCATATGAAACGTCATTCCACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACCTTTGCCCGCAAAGAGCATCTGGACAATCACTTTCGTTCGCATACGGGCGAAACGCCCTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCATATGGTTAACCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGTGATGTATGCGGCAAGAAATACACGCGCAAGGAGCATCTAGCAAATCATATGCGATCGCACACCAACGAGACGCCGTTCCGTTGCGAGATCTGTGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGCGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCACGTGCGCCAGCATACGGGAGAATCGCCCCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTCAATCACATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACGCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACCAAGACGTTCACGCGCAAGGAGCACCTAACGAACCATGTGCGCCAGCATACGGGCGACTCACCGCACCGTTGCTCCTACTGCAAGAAGACCTTCACACGCAAGGAGCACCTGACGAATCATGTGCGGCTGCATACGGGCGACTCGCCGCACAAGTGCGAGTACTGCCAGAAGACGTTCACACGGAAGGAGCACCTGAACAACCATATGCGCCAGCATTCTAGCGACAATCCGCATTGCTGCAACGTTTGCAACAAGCCGTTCACCCGCAAGGAGCATCTGATCAATCACATGTCGCGCTGTCACACCGGCGATCGACCCTTCACCTGCGAGACATGCGGAAAGTCGTTCCCCCTCAAGGGCAACCTGCTCTTCCATCAGCGCAGCCACACCAAGGGCCAGGAGATGGAGCGTCCGTTCTCCTGCGAGAAGTGCCCCAAGAACTTCATCTGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGCGAGAAACCGCACGCGTGCACTCTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCGCAAATACCGGCTGGTGTGCTGACGCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCACCACTCGGCGACCACCACGATGCACACCATCCAGCAGATAACGGCCGGTGCTGCCGGCGGAGCGGGTGCGGTCCAACTGACGCCGGGTCTGGTGCCGTTGCATCCGGTGGTTTACTAA
- Protein Sequence
- MQHVSAASSVPSVVAPVVTTGGTTITLGGPPPLPKSENKEDGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGGNGLPVATSSGGQQGSATVTTTSSTASSGSGGSGSGGTTTTAGELLMPKMEGGIHGVDGQSTVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFSCEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAGGAGAVQLTPGLVPLHPVVY
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00478871;
- 90% Identity
- -
- 80% Identity
- -