Damb004932.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila ambigua
Gene Symbol
-
Assembly
GCA_018150905.1
Location
JAECWS010000100.1:13659522-13662200[-]

Transcription Factor Domain

TF Family
THAP
Domain
THAP domain
PFAM
PF05485
TF Group
Zinc-Coordinating Group
Description
The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion. It features the conserved C2CH architecture (consensus sequence: Cys - 2-4 residues - Cys - 35-50 residues - Cys - 2 residues - His). Other universal features include the location of the domain at the N-termini of proteins, its size of about 90 residues, a C-terminal AVPTIF box and several other conserved residues. Orthologues of the human THAP domain have been identified in other vertebrates and probably worms and flies, but not in other eukaryotes or any prokaryotes [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 2.3e-11 3.5e-08 33.9 0.5 6 84 8 72 3 74 0.75
2 3 4.1 6.2e+03 -2.2 1.0 31 64 448 482 429 511 0.61
3 3 0.097 1.5e+02 3.0 3.0 49 74 593 618 565 629 0.59

Sequence Information

Coding Sequence
ATGTCGAGCTACTGCGGTGCCTGTCGAAAGAGAACCAACCTGAAAACGTTTCGAATGCCAGTTAATGAACAAAAAAGAAAATTATGGGCTGATTCGCTGGATATCGAATACACAAATCAAAGAATTTGCGAGAATCATTTTAAAAAGACTGATTTTTACTATGCCGACAGTATGAATAGTAAACGGCGACTTCGACTGCGCCCCGAAGCCATTCCAGAGCAATGTTTATTGTTATTTAAGGACAAAAAACTAGGCTCACCGTCAGAAAACGCAGAGCAAGGAGAGAACCAGACAAACGATGAAACGGAAGCCGCTCCCAGCTACGATAATTATCAAACAGAAAACCCATCGGCCGCTTCGTGTGAAAGTCCGCCCATTGATGAAGATGACTCCCTTGACTCCATGTTTCTCGAAGATGACGATCCCCTGGCAGGCGAAGACAACAAGGAAACTGTTAATCAGTTGATGAAATGTCGGGCCTGCTATCGGGACTATCAGTTTGACTCGAGTGCCAAAGATGTCTTCGTCAAGCAGAACGCTGTTTTGCTGTATCGTATCGAAGTCATTTGCGGAGTTTGGCTCACCAGCATCGAAGGCGGACCACGTTACATGTGTCCGGATTGTCAGTCGGCCCTGAATACGGCTATTGAGTTCCGCGAGAAGGTCATAAGTACGGAGGTGACGCTAACGCAGGGCAATCCCGTGTGTGATATTGCCGCTGTAGAAGTAGAGTTGGACTCGGCTGATAATTATCAAGGAACGTCAACGATTGAGTGGCCCTTGGGTTTGATTTGTAAGGAAGAGGATGAGGAGGCTAAGGCACAGAGCACTATCCATAGCCCGAATATAGAAATGCTAGAGCCCCTGGAGGAGGACATCGGTGCAGACCCGTCAGATCCACTGAGCGTTGCTCGTGGCACCGATATCCTCAAGGAGCTGGTAATAGAACTAATTGGTACAGATAAAGTCAACCCTGAGAGGCCAGCCAGAAAAACAAAAGTAGATGGCGAGGAAGAGGACGAAGAGACCATAGAAGATGCCATTGAAAATTACATGGACGACGTCATTGAAGAGGAAAGCAGCGAACAGGCCAAGAAGCAGGACAAGAAAAAGGCAAAGAAGGCAAAGGCTCGCGAGGCACAGCCCAAACGAAAGGTGAACGCCAAATTGAAACGGGAACGGGAACGCATCCGTCTCGCCAAGATGAGGGAAAAGCCACCAAACTATGTGTGCGATCAATGCGGATCGGCCTTCCATTTGGTGCACAATTTACAAATTCATATGCTTCGTCATAGCCGCACAAAGAACTTCCAGTGCACGGAATGTCCAATGAAATTCTACGATGCCTACATGAGAAACATTCACATACGCGTTCGTCACAAGGGCGAGCTGCCCTTCGCATGTAGACATTGCTCCGAGGCATTTACAAATGCTGGCGCCCGTCATACTCACGAGTGCAAATTACATGGCGTAAAAGTACCCCAAAGTAACAGTAAAGCCGTTGCCAAGGAAAGGCAACCACCGCAGCGCTTCTTTTGCGAAACTTGCGACAAGAGTTATGTCTCAAAGTACGCCTTAGCCTGGCACGTCAAATCGCATGCAGAGGCGAACGCCTTCAAATGCAAACTGTGCGACAAGAGCTACAATGCGCCAGCGATGCTGAAGCAACACGAAAGGGTACACAAGGAGCGACCACTGCAGTGCGATGTCTGTCTGAAGGGATTTTATCAGCGCACCAAGCTCAAAGCTCACAAACTTATACACTCGGGCGAGCGACCACATCGCTGTGAACTTTGTAACGTTCATTTCCGTTATAAAACAAATTTAAAGACCCATGAGAACACGAAAATGCATCAGGAGAATTTGAGAAAGGTTCATGAGAGTGTAACCGTTGATATTGAATAA
Protein Sequence
MSSYCGACRKRTNLKTFRMPVNEQKRKLWADSLDIEYTNQRICENHFKKTDFYYADSMNSKRRLRLRPEAIPEQCLLLFKDKKLGSPSENAEQGENQTNDETEAAPSYDNYQTENPSAASCESPPIDEDDSLDSMFLEDDDPLAGEDNKETVNQLMKCRACYRDYQFDSSAKDVFVKQNAVLLYRIEVICGVWLTSIEGGPRYMCPDCQSALNTAIEFREKVISTEVTLTQGNPVCDIAAVEVELDSADNYQGTSTIEWPLGLICKEEDEEAKAQSTIHSPNIEMLEPLEEDIGADPSDPLSVARGTDILKELVIELIGTDKVNPERPARKTKVDGEEEDEETIEDAIENYMDDVIEEESSEQAKKQDKKKAKKAKAREAQPKRKVNAKLKRERERIRLAKMREKPPNYVCDQCGSAFHLVHNLQIHMLRHSRTKNFQCTECPMKFYDAYMRNIHIRVRHKGELPFACRHCSEAFTNAGARHTHECKLHGVKVPQSNSKAVAKERQPPQRFFCETCDKSYVSKYALAWHVKSHAEANAFKCKLCDKSYNAPAMLKQHERVHKERPLQCDVCLKGFYQRTKLKAHKLIHSGERPHRCELCNVHFRYKTNLKTHENTKMHQENLRKVHESVTVDIE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00611587;
90% Identity
iTF_00611587;
80% Identity
iTF_00474744;