Basic Information

Insect: Drosophila algonquin
Gene Symbol: grau
Assembly: GCA_035041765.1
Location: JAWNKY010000952.1:789900-791907[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 8.5e-07 7e-05 23.2 0.3 2 23 307 328 306 329 0.94

2 8 2e-06 0.00016 22.1 0.9 1 23 337 359 337 359 0.96

3 8 0.085 7.1 7.5 1.5 1 23 367 392 367 392 0.90

4 8 0.00033 0.028 15.1 0.7 2 23 398 419 398 419 0.97

5 8 0.061 5.1 7.9 0.2 2 23 428 451 427 451 0.86

6 8 8.8e-05 0.0073 16.9 2.0 1 23 458 481 458 481 0.96

7 8 7e-06 0.00058 20.3 0.8 1 23 486 508 486 508 0.97

8 8 6.9e-05 0.0057 17.2 3.8 1 23 514 537 514 537 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	8.5e-07	7e-05	23.2	0.3	2	23	307	328	306	329	0.94
2	8	2e-06	0.00016	22.1	0.9	1	23	337	359	337	359	0.96
3	8	0.085	7.1	7.5	1.5	1	23	367	392	367	392	0.90
4	8	0.00033	0.028	15.1	0.7	2	23	398	419	398	419	0.97
5	8	0.061	5.1	7.9	0.2	2	23	428	451	427	451	0.86
6	8	8.8e-05	0.0073	16.9	2.0	1	23	458	481	458	481	0.96
7	8	7e-06	0.00058	20.3	0.8	1	23	486	508	486	508	0.97
8	8	6.9e-05	0.0057	17.2	3.8	1	23	514	537	514	537	0.98

Sequence Information

Coding Sequence: atggaTATCTGCCGTTTGTGTTTGCGCGGAATTGGCGGAGCCCAGATGTGTCTGCAGATCTTCGATGCAGCGGACAGCAAGGTCGCCGAAGTGCTGCGCCAGCATTTCTGGTTCGAGGTTCTGCCCAACGATGAGATATCCAAAGTTATCTGCAACGTCTGCTGGACGCAGGTGTCCGAGTTTCACCAGTTTTATATTTCCATTCAAGAGGCTCAAGTGATTTATGCCACCACCTCGAAATTCAAACAGGATCCCGAGGCAGCGAACACATCTTGGCCGGAGGAAGTACTAATGCCAGCAGATGTGCTGGCAGTGGACAATGATGTCAGTGCGCAGATAAATGTGAATCCCCTGGATGAGCTAGAACTAGGCCAGACTCTGTCGCCGGAATCTCCAGTCGACAGTAAGCTGGACATCAAAACTGAGCGGCAAACCCCAGATCTGGAATTTGTCCTCGAAGAACCCaacaacgatgatgatgatgatgacgacgacgacgacaacgacgatgaTAATGGTGATGACTATGAAGATGAGGAAGACGATTTAATTATTACGAGGAGTGGCCGCAAACGGATGGGCAGAGAAGGTGTCGCCAAGCCAGACAAGACGAAAAGGATTGTACAGACGGGAAACAAGGGCAAAGCTAAAATTAAGAAACCTAAACCGGTGAAAAGAGTATTTAAGATGGAACGCTTGCCGCCGTTCTGCAAGGAAGATGAGGAACTCATAAAGCGATACATTGTGATGGGCTGTGAGCTGTGCATATTTTTGGCTGAAGACTTCGACGGTATTCGGGAGCACTTCAAGGAGAAGCATCCAGATGAACGGCCCTACATAAAATGTTGCGGCCGCAAGCTAAATAAACGCTGTCTCATCCAAGAGCACGCAAGAAGGCATGAGAATCCGGAGTATATTAAGTGCAAGGATTGTGGCAAGGTGTTCGCCAACTCCAGCGTATTGCGCGCTCATTGGCTAGTTCACCATGTTCCCGATGAGGAATGCGACTTCCAGTGCGAGGATTGTGGAAAGCGCTTCTCCCGCCGTAATCTACTCGAGCTGCACAAGGGCTCCCATGTGCCAGTAAACGAAAGAAAGTTCATTTGTCCCGAGTGTCCCAAGCACAATGCCTTCGCAACGGAATACCACATGCAGGTCCACATCAGCATGCAGCATCGCAAAGCGGCGAATGTGTGCCATGTGTGCGGCAAGAGTATCAAGGACAAGGCCGTCTTTGAAAAACATGTTCGCCTGCATTTTGAGGAGAGTGGGCCACGCATCAAATGCCCCCGACCAGACTGCGAGAGTTGGCTGAAGGACGAGGATAACCTCAAGCAGCATTTGAGGCGTCACAACGACGAAGGCAAGCTTTTCATTTGCTCGGAGTGTGGCAAGAGTTGCAAGAACTCTCGTGCGCTGATCGGTCACAAGCGATACTCCCACTCGAATGTGATTTACACTTGTGAACAGTGCGGCAAAACGTTCAAAAAAGATATAAGCCTTAAAGAGCACATGGCCCAGCACACTGGCGAACCTCTGTACAAGTGTCCCTTCTGCCCACGCACCTTTAATTCGAATGCCAACATGCATTCGCACAAGAAGAAAATGCATCCAGTCGAGTGGGACATTTGGCGGAAAACGAAGACAGGAAGTTCTCAGAAGATTCTGCCCAGTGCACAAGTGAGCCAGATGTTCAGagacgatgccgatgccgcaGCTATTGCCAATGACTACACTACAGCTTAG
Protein Sequence: MDICRLCLRGIGGAQMCLQIFDAADSKVAEVLRQHFWFEVLPNDEISKVICNVCWTQVSEFHQFYISIQEAQVIYATTSKFKQDPEAANTSWPEEVLMPADVLAVDNDVSAQINVNPLDELELGQTLSPESPVDSKLDIKTERQTPDLEFVLEEPNNDDDDDDDDDDNDDDNGDDYEDEEDDLIITRSGRKRMGREGVAKPDKTKRIVQTGNKGKAKIKKPKPVKRVFKMERLPPFCKEDEELIKRYIVMGCELCIFLAEDFDGIREHFKEKHPDERPYIKCCGRKLNKRCLIQEHARRHENPEYIKCKDCGKVFANSSVLRAHWLVHHVPDEECDFQCEDCGKRFSRRNLLELHKGSHVPVNERKFICPECPKHNAFATEYHMQVHISMQHRKAANVCHVCGKSIKDKAVFEKHVRLHFEESGPRIKCPRPDCESWLKDEDNLKQHLRRHNDEGKLFICSECGKSCKNSRALIGHKRYSHSNVIYTCEQCGKTFKKDISLKEHMAQHTGEPLYKCPFCPRTFNSNANMHSHKKKMHPVEWDIWRKTKTGSSQKILPSAQVSQMFRDDADAAAIANDYTTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00494594;
90% Identity: iTF_00481054;
80% Identity: -