Dalg007866.1
Basic Information
- Insect
- Drosophila algonquin
- Gene Symbol
- -
- Assembly
- GCA_035041765.1
- Location
- JAWNKY010001574.1:1251454-1253350[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 7 4.6e-05 0.0038 17.8 3.4 2 23 364 386 363 386 0.95 2 7 0.0022 0.18 12.5 4.7 1 23 394 417 394 417 0.96 3 7 6.1e-06 0.00051 20.5 1.1 1 23 422 444 422 444 0.98 4 7 1.2e-05 0.001 19.6 0.4 1 23 453 476 453 476 0.91 5 7 2.7e-05 0.0023 18.5 1.5 1 23 482 504 482 504 0.97 6 7 5.1e-05 0.0042 17.6 0.7 2 23 511 532 510 532 0.96 7 7 0.0004 0.033 14.8 0.7 2 23 538 560 537 560 0.97
Sequence Information
- Coding Sequence
- ATGGTGGTGTGCGGGAGCATTCTGGCACGGAGCAATTACGAAAATTTCGTATTGAGCTGTGGGCTGAGCAATGACTGCGACGTGCAAATGGACATTGAGAGGTGGAAGGAGTTCGTCCTGCACATTAAGCGGCACAGAGAAGAGGATCAGGAGAGTGATAGCGACTTCGATGCCAGTGCGAGCAGCGACAATTCACCAACAGAGTCAAAGCAGTGTGGGCCGACTGTGAAGGATGCTGAAGATTGTTTAGCCGAAGGAATGATTGTAGATCTTCCCATATCAtccgatgaagatgatgacgACGAAGTAGACTCCTCATCAATGCCGGTTGCATGCGAACTGGGAGGAGCACGAGCACATACAACAGCTGACTTCTCGCCAGTAGTAAAATTTAATCCAACTTTCTACCGACGCAGTCCACGAATTACTCAATTCATCGAGCTCTATAAAGATCATCCTTGCCTCTGGGATCCTTCAGATCCGTCCtataaaaacaaagaagaacGTACCCGCGCATACGAGTCCCTGATGCAGAAGTTGAAAGCGTCTGTCAACATTCATCTGACGATCTATAGGCTGAAAAAGTCTATAGCAAGTCTGCACTCCCAGTATGCAGCAATAACGCGgcaaaaaaagatacaaaaactGACCAAGGTCCCATTGTACTATCATGCAAAATACCACTTTTTGGCGGAGCGAGGAAATGTGGAAGAAGGTGACAGCGATGACGATGGCGGCGATGGAAAGATCAAGCTCCTGTTTACGGAAGAAAATGTGTTGACGAGTCTGTTTATTAAACTGTATTCAAAATTTCCCCACCTGTACGATCCGGCTCACAAGAACTTCTCGAATCTTAGTGAGCGTAAAAATGCTTATATAGAAATAACAGATGTTCTCTCCTCAAAAGTTTCACTGGGGATTATCACCCACTACGATGTCTACGACAGCATTCTCAGCCTACGCCAGTGGTATTCTCGAAAGATGAAGACTCTCACTGAGGTTCAGACTGTCGGCCTATCGACGGCTGAAAAGGAGTACATTGAGAGGTGCCAAAATTTTATGCCGACAAAAACGTTCCGTCAGAAGTTACAGTGCCATGGTTGTCAGAAAAGTTTTAGCACTGATCACGCGTTGCAGGCCCATCAGTTCAAAGATCACAAACTGGGCGAAGGCGGCTGGTTTAAATGTCCCTTGTGTGAGCTGAATTTTGAGAGACGGTGTCATCTGCAACAGCACAACCAACGTGTTCATATGAGCAAAACTTTTACCTGCCAAATCTGCAGTCGAAGCTTCGCCTTTGCCAGCCAACtagccacacacaaacgctCTCATGATGAGAAACATGTGGACAAGCCGTATATCTGCGAATTCTGTGGAAAATCTTTTAGACAGAAGATTCAGCTGAGCACGCATGTAACGGCCGTGCACACCAAAATTCGCGCATTCAAGTGCACCATGTGTCCCAAAGACTTTTTTACTAAGCGCGATCTCAAGGATCACGTTAAGGCGCACTTAAATATACGCGACAAGGTGTGCGAGGTGTGCCAGAAAGCCTTTACAAACGCCAACGCCCTGGTCAAGCATCGACATGTACACCGGGAGAAAACGCTTCAGTGCACTCTCTGCAGCACCCGTTTTTCTGAGAGGGTTAGCTTGGGTGTTCACATGAGGCGCACACATAAGATTATTAAGAACACTTTGAAAGGGGCTGAGACTTCCAACGACGCCCTACTCAAACATACATTCCCACAATCTAACGACATTTCagacaaataa
- Protein Sequence
- MVVCGSILARSNYENFVLSCGLSNDCDVQMDIERWKEFVLHIKRHREEDQESDSDFDASASSDNSPTESKQCGPTVKDAEDCLAEGMIVDLPISSDEDDDDEVDSSSMPVACELGGARAHTTADFSPVVKFNPTFYRRSPRITQFIELYKDHPCLWDPSDPSYKNKEERTRAYESLMQKLKASVNIHLTIYRLKKSIASLHSQYAAITRQKKIQKLTKVPLYYHAKYHFLAERGNVEEGDSDDDGGDGKIKLLFTEENVLTSLFIKLYSKFPHLYDPAHKNFSNLSERKNAYIEITDVLSSKVSLGIITHYDVYDSILSLRQWYSRKMKTLTEVQTVGLSTAEKEYIERCQNFMPTKTFRQKLQCHGCQKSFSTDHALQAHQFKDHKLGEGGWFKCPLCELNFERRCHLQQHNQRVHMSKTFTCQICSRSFAFASQLATHKRSHDEKHVDKPYICEFCGKSFRQKIQLSTHVTAVHTKIRAFKCTMCPKDFFTKRDLKDHVKAHLNIRDKVCEVCQKAFTNANALVKHRHVHREKTLQCTLCSTRFSERVSLGVHMRRTHKIIKNTLKGAETSNDALLKHTFPQSNDISDK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00515110;
- 90% Identity
- iTF_00517945;
- 80% Identity
- -