Basic Information

Insect: Drosophila aldrichi
Gene Symbol: -
Assembly: GCA_035045965.1
Location: JAWNOM010000501.1:8434583-8438689[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.003 0.22 12.1 0.6 2 23 257 279 256 279 0.94

2 9 0.013 0.94 10.1 4.6 2 23 415 437 415 437 0.91

3 9 0.0063 0.46 11.1 2.3 3 23 526 547 524 547 0.94

4 9 0.00031 0.023 15.2 0.7 2 23 780 802 779 802 0.96

5 9 0.0034 0.25 11.9 0.3 2 23 857 879 856 879 0.92

6 9 0.0099 0.73 10.5 3.6 2 23 928 950 927 950 0.96

7 9 0.096 7.1 7.4 4.2 2 23 964 986 963 986 0.92

8 9 0.0026 0.19 12.3 0.5 3 23 1052 1073 1051 1073 0.96

9 9 0.045 3.3 8.4 0.6 1 23 1158 1180 1158 1180 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.003	0.22	12.1	0.6	2	23	257	279	256	279	0.94
2	9	0.013	0.94	10.1	4.6	2	23	415	437	415	437	0.91
3	9	0.0063	0.46	11.1	2.3	3	23	526	547	524	547	0.94
4	9	0.00031	0.023	15.2	0.7	2	23	780	802	779	802	0.96
5	9	0.0034	0.25	11.9	0.3	2	23	857	879	856	879	0.92
6	9	0.0099	0.73	10.5	3.6	2	23	928	950	927	950	0.96
7	9	0.096	7.1	7.4	4.2	2	23	964	986	963	986	0.92
8	9	0.0026	0.19	12.3	0.5	3	23	1052	1073	1051	1073	0.96
9	9	0.045	3.3	8.4	0.6	1	23	1158	1180	1158	1180	0.99

Sequence Information

Coding Sequence: ATGGCCGCATCCATATATGCCACCCCACCGCCGGATCTGAGCAGCGAGGATACAGCGCTCTCCGATGTCTCCAACTCATCCACACTCAACACAAAtcgcggcggcggcagcagcaacaacagcagcaccaacaccaccaacaacaacaacagtcacacacatgaagccacagcagcagcagcagcagcagcaaccactgCAGCAAACACAGCAATGTCACCCACTCTGGAAGCGGAGTCTAAGCCACTTGGAAGCAACACAAATGAGACAGACATGCCACCAGTCGAGGATGAGGTCGagggcgaaggcgaaggcgaaggcgagaACGAGGGCGAGGCAGCTGGCGGTCTGGATCAGACGGCGATGGCTGCaatggctgcagcagcagctaacgcAGCAgccatgcagctgcagctgctcgaggCGCTCAACGATGCGGCCAAGAAGCGGCGCAAGCAACACAATCCCAGTCGTCTGGAGGCGCTCAATCTGAGCGGCGGCGAGCAGGAGGAGGGAGCCGCAACGGGTACTGCGACAGCGGGTCAGTCAGATCCAGCGACAATCGACTACGAGGAGAAGCTGTCGAAGATGTTGCTGCCCAAGTCCATAGAGAAGCTAAAGGAGACAttcgagctgctgcagcagcaaaagctgcAGCCCGAAGACATATCAGAAGCGGAggagaaacagcaacagcaacagcagcagcagcaacagcaagaggaggagcagcagcagcagcaacagctaattAATCCCTATCAGACCTATTGCAAGCAGTGCGGCGAGAACTTTGAGACAGAGTTCAAGCTCAGTCTGCACATGTTGCAGGATCatcagcagccacagcagcaacaccaacagcaacagcagcagcagcaacagttgtcgTCTGACGAGCCCATGGACTTGCTGGCCTCCATCAAAGTGAAGCTGGAGCGCGCTGAGAGTCCCtcgcagctggagctgcagcagcaacaacagcaactggaatTGCCCAACGGGCATGCCGGCAGCAACAAAGAGCACGAACTTTGGCTACAGGCCATggctcagcaacagcagcagcagcaacaacaccaacagcaacagcagcagcagcatcagcaactgCCCGGCATGCCGCCCGCTTTTGCATTTCCGCCAGAGGCTGCACTTGGCTGGCCACTTCTGGGCATGCCTGGCTTTGCCGGCGTCGATGGACTCAATCGTCCGCCGTTGCGCATCTTTAATCCGGAGGCCTACTGTGAGCTCTGCAACAAGGAGTTCTGCAACAAGTACTTTCTGAAAACGCACAAGGCCAACAAGCATGGCATCTTTGATCCAGCTGGTGATATGACCACGCccaacaacaatatcagcaccatcagcaacaacaacaacaacaacagcagcagcagcaacaacaaccacagcaacagcaacagtattggcatcagcaacatcaacaacaacaacaataacaacaacagcagcagctcaacttCCATCTTTCCAACGCTGCAAATGCCACGTGAGCCGCCGCCACAGAAACCTGAGCCACAGTTGACACCACCCGCACCACCGGCAGTGCACTGCGATATCTGCTCCAAACGCTTCACCAACATCTTTGCCATGCGTCGCCATCGCGCCAAGCAGCATGAgcaggccacgcccactgcctcGCCGACGCCCAACGAGCAGTCGCCGTCCACAGCACAGGCGGCGGTCAAGCAGGAGCCCACGCCGGAAGCTTTAGCCGTGCCGGAACAGAAGCCGTACCAACTGCCCGAAGGATTTCGCGAGGACTTCACGCTCGAGCAGGAGGAGGTGGCCTTTGCGCCGCCGCCTCGCAAGCTGCccagccagctgcagcagcaggcgcgcGACTCCAACTGGGCGCCAGAGAAGCTGCGACGCCTCGGCGTCCAGCTGCCGGAGGCATTCTGTGAGCTGTGCTGCAAGGAGTACGCCAATCGCTACTTCCTGCGCACGCATAAATGGAAGCGTCATGGAGTCTTTGTGCCGCCCGAGGAGCTGGGCAAAGAGGAGCAGCCGCTGATGCCCGCTGGCTGGCCATTCATGCCTCTGAATCTGATGCTGGCCAAGGCAGCTgccgagcaggagcagcagcagcagcagcagcccgagCAGGACGACGAACAGCaaccgccgcagcagcaacagcagcaacaacagcaagaggaGCAGCCGAGCAAACGCATCAAGCTGGAGCCCTACGACGAGACGACGCCGCCACAGGACAAGCTGGATAACTCCGTGGTGGGTCTGCAGAATCTGCAGAAGCTGCAAtcgatgctgcagcagctcaacgACTTCAATGGCAAGCGGCCGCTGCCCTGTCATCTGTGCGGCAGAGAGCTGGAGCATCAATATGCTCTGCGTGCCCATTTGATGACGGAGCATGCCGGACAGCTGCTGCCCGAGGGACATCCCATGCtctaccagcaacagcagcaacagcaacaacagcagcaacagcagcagcagcagttgccgctGAAGCTATCGCCAGTGGGCGGTGCTGGGGGCTCCCCCAACGCAGTCACGCCCACCCCGAACGAGCTGCGCTGCCAGACGTGCGAGCGCGACTTTGCCAACTCACAGGAATTCAAGCAACATATCGCCGAGGTGCATCTGGGTCGTCTGCCCGGCAGTAGTCCGCTACGCGAGGGCTTCTACACGCCGGAACGTGCAACGGCTGCCGCTGCGGGGGGCGCCGCTGGAGGCGTGGCACCCGGCACACCGCGTGCCGCCTACACCATCACGCCCACCTCCAGCTACTGCGAGATCTGCAACAAGGAGCTGTGCAACAAGTACTTCATGAAGACGCACATGCAGCGCATGCACGGCATCGAGATCGAGAACGGGGCACAGATCGGCGGTGTCGTCTGCAACATATGCAACAAGGAGCTCTGCAGCAAATACTTTCTGCGCGTGCACAAGCACAATACGCACGGCATCATCGAGGATGGCGCTCCGCTGCCTCAGCCGCGTGGCAGTGCACAGAACGGCCTGAAAGTCGaggctcagcagcagcaacaacaacagcaacagcagcagcagcaacaacagcagcagcaacagcagcagcaacagttgctcgaGCCGGAGATTAACCTAACGCCGCTGCGTGGCGAATCAAATGAGCTCTGCCCGCTCTGCGCTCGACAGTTCCGCAGCTCCAAGTGGCTGCGCACGCATCTGATGAACGAACACGGTGCCGCTGGCATCGAGAAGCTGCGCGAGCTGGAGCAGTCGGCcatcggcaacagcaacaacggcagcagcaagccCAACAGTCCCACGCTCAAGATACCCAATGGGAGTGCTGCGGGCGCTGCCAACAATCTGGCCCAGGCGCTGCAGaacgcgcagcagcagctgttcggCCAGATGCAGTTGCCCAAAGGgatgccgctgccgttgccgttgccgggCATGTTCGAGCAGACGCCACGCTTCAAGGAATACCAATGCTCACTGTGCCCCTTCACCACGCCCTACTACGCATTCCTCTTCATACACGAACGCTCCCATGCGCTGCTCAACAATGGAGGCAACGATGGCAACGACGCTCCATTGGAGGCGGATCGAGAGAGAGCATTCGGCGCCGTACAGAGCAAGGCCCGAAGCAAGCCGAGCAGAGAGCGTGCCCTCAAAGCTGAACGCTCCGAAATCGAACCCACAAATCtgaccaccaacaacaacagcaacaacagtaacaacagcaacaacagcagccacagcaaggCAGGCACGCCCACTCCATCGCCAGGCGCGCCTGCCGTCTCGCCCAAAGCCCGTTCAGCCAGTGTGACTCCCATCCACAACTCCAAGCCGGGCACACCCAACGGTCTCCAGGCTCAGCGTTCGGCCGCCACCTCGCCGTTTGAGTTGTGCGCGGATCTGGCCAATGGCAGCGGCAAGCCGGCCAGCTACGCCCAGCCGGACAAGTCAGAGGAGGCCTATCAGATGCAGGCCTTCCATCTGACGCCCgctgatgccgatgccgagGGTCTCTTTGCTCCGGCGCTCGTTTATCTGCCGGTGCGCGTGCGCGCCTCGGAGTCGACCACACTGAGCTTCAGGCTGACGCCGGCCTAA
Protein Sequence: MAASIYATPPPDLSSEDTALSDVSNSSTLNTNRGGGSSNNSSTNTTNNNNSHTHEATAAAAAAATTAANTAMSPTLEAESKPLGSNTNETDMPPVEDEVEGEGEGEGENEGEAAGGLDQTAMAAMAAAAANAAAMQLQLLEALNDAAKKRRKQHNPSRLEALNLSGGEQEEGAATGTATAGQSDPATIDYEEKLSKMLLPKSIEKLKETFELLQQQKLQPEDISEAEEKQQQQQQQQQQQEEEQQQQQQLINPYQTYCKQCGENFETEFKLSLHMLQDHQQPQQQHQQQQQQQQQLSSDEPMDLLASIKVKLERAESPSQLELQQQQQQLELPNGHAGSNKEHELWLQAMAQQQQQQQQHQQQQQQQHQQLPGMPPAFAFPPEAALGWPLLGMPGFAGVDGLNRPPLRIFNPEAYCELCNKEFCNKYFLKTHKANKHGIFDPAGDMTTPNNNISTISNNNNNNSSSSNNNHSNSNSIGISNINNNNNNNNSSSSTSIFPTLQMPREPPPQKPEPQLTPPAPPAVHCDICSKRFTNIFAMRRHRAKQHEQATPTASPTPNEQSPSTAQAAVKQEPTPEALAVPEQKPYQLPEGFREDFTLEQEEVAFAPPPRKLPSQLQQQARDSNWAPEKLRRLGVQLPEAFCELCCKEYANRYFLRTHKWKRHGVFVPPEELGKEEQPLMPAGWPFMPLNLMLAKAAAEQEQQQQQQPEQDDEQQPPQQQQQQQQQEEQPSKRIKLEPYDETTPPQDKLDNSVVGLQNLQKLQSMLQQLNDFNGKRPLPCHLCGRELEHQYALRAHLMTEHAGQLLPEGHPMLYQQQQQQQQQQQQQQQQLPLKLSPVGGAGGSPNAVTPTPNELRCQTCERDFANSQEFKQHIAEVHLGRLPGSSPLREGFYTPERATAAAAGGAAGGVAPGTPRAAYTITPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVVCNICNKELCSKYFLRVHKHNTHGIIEDGAPLPQPRGSAQNGLKVEAQQQQQQQQQQQQQQQQQQQQQQQLLEPEINLTPLRGESNELCPLCARQFRSSKWLRTHLMNEHGAAGIEKLRELEQSAIGNSNNGSSKPNSPTLKIPNGSAAGAANNLAQALQNAQQQLFGQMQLPKGMPLPLPLPGMFEQTPRFKEYQCSLCPFTTPYYAFLFIHERSHALLNNGGNDGNDAPLEADRERAFGAVQSKARSKPSRERALKAERSEIEPTNLTTNNNSNNSNNSNNSSHSKAGTPTPSPGAPAVSPKARSASVTPIHNSKPGTPNGLQAQRSAATSPFELCADLANGSGKPASYAQPDKSEEAYQMQAFHLTPADADAEGLFAPALVYLPVRVRASESTTLSFRLTPA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00502799;
90% Identity: iTF_00532681;
80% Identity: -