Basic Information

Insect: Drosophila aldrichi
Gene Symbol: L
Assembly: GCA_035045965.1
Location: JAWNOM010000161.1:2378419-2387581[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1e-05 0.00075 19.9 2.9 1 23 168 190 168 190 0.98

2 17 0.35 26 5.6 6.2 1 23 196 218 196 218 0.97

3 17 1.7e-07 1.2e-05 25.5 3.2 1 23 224 246 224 246 0.99

4 17 1.2e-05 0.00091 19.6 0.4 1 23 252 274 252 274 0.99

5 17 0.014 1 10.0 0.2 2 23 355 379 354 379 0.93

6 17 0.0003 0.022 15.2 0.2 2 23 403 425 402 425 0.96

7 17 0.061 4.5 8.0 0.7 1 23 500 522 500 522 0.97

8 17 0.072 5.3 7.8 0.3 2 23 530 551 529 551 0.91

9 17 0.02 1.5 9.5 1.2 3 23 562 584 559 584 0.86

10 17 3.2 2.4e+02 2.6 1.0 2 23 620 642 619 642 0.95

11 17 0.0025 0.19 12.3 1.1 1 23 688 711 688 711 0.97

12 17 0.0064 0.47 11.1 1.6 2 23 886 908 885 908 0.96

13 17 0.11 8.4 7.1 0.1 1 23 914 936 914 936 0.92

14 17 0.25 19 6.1 0.6 2 23 944 965 943 965 0.96

15 17 0.31 23 5.8 1.3 1 23 1059 1081 1059 1081 0.94

16 17 0.0081 0.6 10.7 0.0 1 23 1091 1113 1091 1113 0.96

17 17 0.00022 0.016 15.7 1.2 1 23 1118 1140 1118 1140 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1e-05	0.00075	19.9	2.9	1	23	168	190	168	190	0.98
2	17	0.35	26	5.6	6.2	1	23	196	218	196	218	0.97
3	17	1.7e-07	1.2e-05	25.5	3.2	1	23	224	246	224	246	0.99
4	17	1.2e-05	0.00091	19.6	0.4	1	23	252	274	252	274	0.99
5	17	0.014	1	10.0	0.2	2	23	355	379	354	379	0.93
6	17	0.0003	0.022	15.2	0.2	2	23	403	425	402	425	0.96
7	17	0.061	4.5	8.0	0.7	1	23	500	522	500	522	0.97
8	17	0.072	5.3	7.8	0.3	2	23	530	551	529	551	0.91
9	17	0.02	1.5	9.5	1.2	3	23	562	584	559	584	0.86
10	17	3.2	2.4e+02	2.6	1.0	2	23	620	642	619	642	0.95
11	17	0.0025	0.19	12.3	1.1	1	23	688	711	688	711	0.97
12	17	0.0064	0.47	11.1	1.6	2	23	886	908	885	908	0.96
13	17	0.11	8.4	7.1	0.1	1	23	914	936	914	936	0.92
14	17	0.25	19	6.1	0.6	2	23	944	965	943	965	0.96
15	17	0.31	23	5.8	1.3	1	23	1059	1081	1059	1081	0.94
16	17	0.0081	0.6	10.7	0.0	1	23	1091	1113	1091	1113	0.96
17	17	0.00022	0.016	15.7	1.2	1	23	1118	1140	1118	1140	0.97

Sequence Information

Coding Sequence: ATGATGGCCTTAAAGATGTTGTATCGCGGTCCCAGTTCGCGTTTagagaatttaattgaaaagattCAAGCGACCAAGGAGATAACTAACAACGATATGTACAGCACGCACACTTCGTCGAGCTATTCGCCCAGCATCTCGGATGGCACTTTGACGCCCAATTCAcagctgcagtcgcagtcgcagttgcagtcgcagtcgcagtcgcagcagccaCAGACTGCCTCGGAGGAGACAGGCGAGGAGTCGGCCAAGGCGAATGGCGATGCTGCACAGCAAACGGaactggagcaggagctgagCAAACCGAAGCGACCGGCACAtttgcatcatcatcatcatcatcattatcatcatcagcaggcgcTGAAAATAGCAAACAAGCTGCGCAAAATCAATAAGGATGCAAAACTGGCTGCaggacaaggacaaggacaTGGCACAGCCGCCAAGTTTGATAAGTTGACAGGGGAGGGGATTAAAAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCACGGCTCGGCTACCTCAAGCATCACGTGCAGaGTCATGCCGAGCATTTGCCTTTCAAGTGCGAGTACTGCGCAAAGCTGTTCAAGCACAAACGTTCCCGAGATCGCCACAAGAAGCTGCATACAAATGAGAGGAACTACAAGTGTCCGCATTGCGAGGCTGCTTTCTCCAGAAGTGATCATCTGAAGATCCACATGAAGACGCACGATATACAGAAGCCCTTCCAGTGCAGCATGTGCAATCGTGGCTACAACACAGCCGCCGCCCTCACCTCGCACATGCAGAAGCACAAGAAGAACGCCGCAATTCTCGCAGCTGGCGGCAATCCCAATGCGCTCAATTACAGTCCACGCTCCACGGGTTCCGCCTCGATCTCGAGCAATGGAAGCCTGCATAAGCGTCGCTATGCCTTGGCGCTGGCCTCCGACAGTAGTCCCAGTCGGCTGGAGTTTCCCAAGCGGGCGCGTGGCCAGCtgacggccacgcccacggcGACAACGATGGCCACACCGACGCCCACGCcgctgctgcgctgcagcTACTGCCCCAAGGCAACGGAGTTCAGCAGCCTCGAGCAGCTCAATGCGCATCTGCAGAGCACGCACGAGCAGcaccagccgcagcagcagcagcagtcgatgGAGTCGGATGGCCAGACGAATGGCTTCCAGTTGAGCTGTGAATATTGCACGATGAAGTTTGTGAATATCGCTGCGCTGTTCCAGCACATGAGAGTCACGCACTTGGATCGCCTGAGCAGTCCCAATTCCTATTACGAGCACTTCAATCGGCTCGGCTCGCCGCAGTCGAAGCTGAAGTCGGATCTGGCGCCAGCGGAGAAGCCCGAGCAGGAGTTGCCCACCGATctgagcagcaacaagcgacGTCCGCTGACCTCgcccacgcagcagcagcagcagcagcagcagccggcgccTGCTCCACCGCCGCCTCCTCCTGGCATCTTCTTCTGCAATCAGTGCAACGCCGGCCTGCCGGACTTTGAGAGCTTTCGCAATCATCTGAAGAGCCACATAGCCGAGGGCATGCAGCTGATCTGTCCGCACTGCGGCCTCAGTCTGCCCGAGCAGTGCGAGTACGAGCGCCATGTGGTCGCCCACTTCCTGATCAGCAGCTCCGAGTTCAATtgctgcagcgccagctgTGGCAAGTCCTATGCCAAGGCGGAGGAGCTGCACCAGCACCTGCTGGCCGAGCACGTCCAGACGATGCTGAAGTGCGTGCTGTGCTCGGAGCTCTGCGAGAATCGCATGTCCATGCAGCTGCATCTGGCCTGCGCCCATAGCCAGGAGTCGAAGCTGTTGCGCTGCAGCGCCTGCCTGGAGCTGTTCCGCAACGATGGCGACTTCCATGTGCATGTGAAGACGCGCCATCAGCTGGGCAACCAGGGCACGCTGTCCGGAGCTAATCCTGCTGCGCCGGCCAATCCGCTGCAGTGCATGTTCTGCCGCGCCGTCTGCTCCTCGGAGCTGGAGatgcatttccatttggcGGCGCATGCGCGACAATTTCGCTGCCCCAGCTGCCCGGAGACCTTCCATGTGGAGTTCCTGCTGGACAGGCATATGCAGAGCCAGCACGGCGGCACCAAGGACAAGGAGTCGCCCGTTCCGGGCGGCATGGGCAGCTTGTATGTGAatgcgctgctgccgcctttggcagcggctgctgctgccgctgccgcagcaaacaatgcgaacaacaacaacaacaacaacaataataatattgattacAATGTCGCCTTCAAGGGTCTCTTTGGCGGCAGCAATCCGCCGAGCAAGTTCTACAACAGCCCGCTCCAGGTGGACACCAAGCAGAGTCCGCATCCGGCGCTCATGTACGGCCTGAGCCAGCGCTATCTGATGGAAATGTACGCCGCAAAGGCCAATTCGCCAGCGGCAGAGCAGAGCACGCCGCAGGCCGTGCAGTCCGTgcagtcagcagcagcgagcgcaagcaacagcagcggcggcggcagcggcagcaacaacaacaacagctacagctgtGGCATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCCGAGCTCCACTCACATCGCAAGCTCGCCCACAATCTGAAGACGGGCGTCAGCCTGCGCTGCGCGTACTGCTCCGGCAACTACAAGAGCCGAgcggagctggagcagcacaTGAAGAGCTGCCACAACTCGAGCGGCAAGCACAAGTGTCTCATCTGCGACGAGATCTTCCCCTCGCCGGCCATTCTCGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGCCAGTCCGGCAAGTGCGCCCACTGCggacagcagctggagcatgTGGCCGCCTTCCGTGCCCATCTGAGCGAGCATGGCAACGATGGCAATCTGCCCATGGCCTGCATCTGCTGCCGCCAGACGCTGCACTCGGAGTTCGAGCTGAGTCTGCATGCCAAATTCCACACCAAGTCGCCCAGTTGCAATAGCCTGCAGGAACCGGTCTGCGCCTTGTGCCTGGAGCCGCTGCCGGGCGCAGGTGAAACGGCCAAGTTGTGCGACAAATGCTGCCGCAAACACAATCTGAATGGCAAGCGCAAGGAGCAGGCGCCGCCCACGAGCATCGCTGCCTCAGCAGCTGGCACCTATCTGGAGCATCGCTGTAATCTGTGCAAGATGATCTTGCCGCATGCCCAGAAGCTGCAGGAGCATCTCGTCGAGCACACCTTCGCGGGCACCGAGCAGCGCGGCTACAATTGCTACATCTGCTCGGCCGTGTTCACGGCGCCCGCTGGCCTGCTCGCCCACATGGCTGAGCATGGCACGCGTCCGTACGACTGCAACTTGTGCCCGGAGAAATTCTACTTTCGTGCCGAGCTGGAGCATCATCAGCGAGCGCACGAGCTGCGCGCTCAGCcggcagcaatggcagcagcagcagcctcagcagcagcagcagcagcagcaacacgtcCGCCTAAGCAGGAGGCGCACAGCTCGACGGCCAGCTCCCCATTGACGCTCAGTCCCAGCCATGTCAAGCAGGAGCTATACGAATCGGAGCCAGCGAATTCGCCCAACCCGGCTGAGCTGCCTgcgcagcaggaggaggaggagtacaTTGAGGTGGAGCAAATGCCGCAGGAGACGCTGCGAACTGGCGAACTACTAAGCACCGAGCgttccagcagcagcgcctaA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSQLQSQSQLQSQSQSQQPQTASEETGEESAKANGDAAQQTELEQELSKPKRPAHLHHHHHHHYHHQQALKIANKLRKINKDAKLAAGQGQGHGTAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGQLTATPTATTMATPTPTPLLRCSYCPKATEFSSLEQLNAHLQSTHEQHQPQQQQQSMESDGQTNGFQLSCEYCTMKFVNIAALFQHMRVTHLDRLSSPNSYYEHFNRLGSPQSKLKSDLAPAEKPEQELPTDLSSNKRRPLTSPTQQQQQQQQPAPAPPPPPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLICPHCGLSLPEQCEYERHVVAHFLISSSEFNCCSASCGKSYAKAEELHQHLLAEHVQTMLKCVLCSELCENRMSMQLHLACAHSQESKLLRCSACLELFRNDGDFHVHVKTRHQLGNQGTLSGANPAAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGTKDKESPVPGGMGSLYVNALLPPLAAAAAAAAAANNANNNNNNNNNNIDYNVAFKGLFGGSNPPSKFYNSPLQVDTKQSPHPALMYGLSQRYLMEMYAAKANSPAAEQSTPQAVQSVQSAAASASNSSGGGSGSNNNNSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLSEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCNSLQEPVCALCLEPLPGAGETAKLCDKCCRKHNLNGKRKEQAPPTSIAASAAGTYLEHRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAPAGLLAHMAEHGTRPYDCNLCPEKFYFRAELEHHQRAHELRAQPAAMAAAAASAAAAAAATRPPKQEAHSSTASSPLTLSPSHVKQELYESEPANSPNPAELPAQQEEEEYIEVEQMPQETLRTGELLSTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: iTF_00502755;
80% Identity: -