Dald015227.1
Basic Information
- Insect
- Drosophila aldrichi
- Gene Symbol
- -
- Assembly
- GCA_035045965.1
- Location
- JAWNOM010000511.1:999395-1003953[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 3.7 2.7e+02 2.4 0.0 1 23 362 387 362 387 0.92 2 17 0.0068 0.51 11.0 1.6 2 23 398 419 397 419 0.94 3 17 5.5 4.1e+02 1.8 3.0 2 17 430 445 429 456 0.75 4 17 0.024 1.8 9.2 0.3 3 23 489 509 487 509 0.95 5 17 0.00025 0.019 15.5 0.3 1 23 517 540 517 540 0.98 6 17 0.0009 0.067 13.7 0.5 2 23 545 566 544 566 0.97 7 17 0.071 5.2 7.8 0.0 1 20 574 593 574 595 0.94 8 17 0.00062 0.046 14.3 0.3 1 22 614 635 614 638 0.90 9 17 0.018 1.3 9.7 0.7 1 21 643 663 643 664 0.93 10 17 0.004 0.3 11.7 0.5 1 23 683 708 683 708 0.97 11 17 0.036 2.7 8.7 2.0 2 23 724 746 723 746 0.94 12 17 0.0023 0.17 12.5 0.2 3 23 753 774 751 774 0.92 13 17 0.0052 0.38 11.4 0.3 2 23 778 800 777 800 0.96 14 17 7.1e-05 0.0053 17.2 3.2 1 23 806 828 806 828 0.98 15 17 0.0081 0.6 10.7 0.8 1 23 832 855 832 855 0.94 16 17 0.00017 0.013 16.0 1.5 1 23 861 884 861 884 0.97 17 17 0.00045 0.033 14.7 2.0 1 23 888 916 888 916 0.92
Sequence Information
- Coding Sequence
- ATGTCGGAAAATTCGAAAATAAACAACGAAAATGGACCTATCTGCCTGCATTGCGGTGTGCACAGTTCAAAACACCAATATCAAGAAATTTTCGATGAAGTGGGAATCGAAATTGAGCTCGCTAATCTTTTGGCGAAGTATTTCCAAGTCGTCGTCAAATCCGATGCCCACAAGCCGCAATTACTGTGCGAAGAATGCGTAAAAACGCTAATACGCTTCTTTGACATAGAcgagctgcagcggcagcaggatGCTGCCAATGCAGCCAAAAGGGCTGCCAAAAAGGCTGCCAAGCCGCCAGAGGATTTACCAAGTACTGTTAAAAAGGTAGGGATATCAGCTAAAAAGGTGACGCCGACGCCGTTACCAAAGACAAAGAGCGTCGCTTCTCCAGTCAAAAATTTACCAAAACCCGAaacagttgctgccactgGTGTGGCTACAAGCGCAGCAAAAAAATCGATCTTAACAGTTCTGCCCAAACGTTTGCCCGATAAGGACAAGGAGGTAGTTAAACGAAATGTCAAAGACAAGGTGAAAACTCATGGCGCGGCAGATCAGGAACAAATCAGCGCGCTCATACGCGACATTCTGGATGATGAGGAGCCGCCGACCGATGATAAATTTGCCGAGGCAGCAGCCACAGTGCGGCAGCTGGATAAGCAAACTAGCAAAAACCAGGGACAGCAGGAGGCAGTGCCAAAGCAGCTGGGACAGGAGGAAGAGGATAACAATGACGAGCTGGAGTTTCTGCTGGAGCAAGATGAAAACTCATCCGATGCGGACGTGCGTCATTTCAAAGTAGAGCGCAAGGTCAAACGCTCGGCTTCCCAATCGCAGTCACAAAATGAAAGCCAAAGCGAGGATGATTCATTGAAAGTGGAGCCCTTTAATTTTGTCCTAATTAAAGAATCTGACAACATTGGCGATCTGCATGAATATCTATCGACTGTGGTGAAGACCTGCTTTGAGACCTTGCAATTCGATTGGGCCACTGTTTGCTGCCATTGCTCGctgaaatgcaacaaatttgaaaCTCTGCTCGGCCACATGCAAAAATGCCATCAGCTGGACGACGAGCGCTATATATGTCCCATTGAGGGCTGCAAGGCGGAGCTGAAAGGACGCAAATATTTGGCCATGCATCTGGTGGTGCTGCATGCACCTGTGGCAGAAATACCCATTTATGGCAAATGTCCCGAGTGCAATATGACCTTCTCCAATATATTGCAATATAATAAACACTCTTGCGCACATGTAATTAAAAAGCGTCGCGGCATGCGCTTATACTGTGAGATGTGTGGCCTGGAGTTTCCCTCGTGGAAGCGCTTTAATTTCCACAATCAATTCCATTTGGAGCGTCACAGGCCACGCGCTTGTTTCGTTTGCGATTTTGCAGACAACAACATCGATGAGCTCTTCCGTCACTTGTATTATGCCCACGAGCCGGAGGGCACACTCTTTTGTGATCTCTGTGATCGCAACTTTCGTGACGCTGCCGTCTTTATGGAGCACAACAAATCGCATGCGAATGTCAGCAGCACCACCTACAGCTGCTCGGAGTGTAACGCCAACTTTGAGACACGGGGTCGTCTCAACGGTCATATGCGCTCCATTCACGGCAGTGCCATCAGCTGCGAGTTGTGCAGCCGCGAGTTTTCCACAGAGGCGACCTACAGCATGCATATGAAGTCGCATTTGATCATTGAGCGTCAGGTGCACGTGTGCAGCGGCTGTGGACTGCTCAGCGACAGCAGCGCGAAACTGCAGGCTCATATGGAGGCGGAGGATTCGGCCTGCTTTGGCTCGGAGACGTATGCGGAACTGTTGCGCAATGCTTACGTCTGTGAATATTGCTCGGCATACTTTAAGGAGAAGAGTGATCTGCGTGCCCATCGCGATTCGGGCGTGCATAAGAACGGATTATTCATATGCCAGCCGTGTGACAAGCCCTTTTCCGACATGAAACTCTATCGTCATCATTTGCGCAACTTTCAGCAACAGCGCTCAGATATAGCGCATCGCAAGCTAGAGATATGTGTCTTCTATATGTGTGACTATGAGGATTGCACTGAGGCCTACATTAACTGGAACTCGCTGTACACACACAAGCGACGTTCGCACGATGCCATCACGAGACATGAGTCGCTGGTCAAGGATAACGAATGGGTCTGCCAGTTCTGTCAGAAGCAATGTCGATCCAAAATGTCACTATCGGTGCATGTGGCGCGTAGTCATAATAATAATAATGTCATATGCCCGCTGTGCAAGGCCTCCTATAAGGATAGCGATGCGCTGTCTAAACATCACGCCTATTGGCATGAGCCCATGGAATGCAGTGTCTGCTTGAAAGTGGTCAAAAATCGTCGCAATTACGATACGCACATGAATGTGGTGCATTCGAATAATAAACGCTACTCGTGCAGCTTCTGCCAAAAGGGCTTCTATCATAAAAGTGAAATGGAGGCGCATCAGCGGCTGCATAGCCAATCGTATAGCTGCAACCAGTGCAGCTTCGTCACAAGGAACAGGAAGTCGCTGTCGGTGCATGTGATGGGACAGCATTACAAGCGATTTGCATTCGAGTGCAAGGCGTGCAATAAGCGTTTTGGACGTCGCCAGGGTCTGTCGAATCACATGCAGCGTACGCATGGCTCCCGTTATACGTGTCAGGATTTCTTCGATGGTGGATGCAGCAAATCGTTTAGTTCGACGACGCACCTGAAATTGCATGTGCGTAAAGTGCACAATGGCAGCATTTATCTAGAAGATGAGTCAGTGAAGGCCGAGGATCTAGATGAGCAGGAAGAGGAACAggaagaggaggagcagcagcagctggaacagGAGGAGGATGAACAGAAGGACGGCCCGTCGTCATCGAAGAAACGCTGTATACGCATCAATGGGAATACACAAATCGAGTTTATTGGCGACGCCACGGAGAATAAGGATAAGGAGTTGTTGTCGGAGTTGCAGGAGCCCAAGTCGAATAATaagaggcagaggcaaaaaTAA
- Protein Sequence
- MSENSKINNENGPICLHCGVHSSKHQYQEIFDEVGIEIELANLLAKYFQVVVKSDAHKPQLLCEECVKTLIRFFDIDELQRQQDAANAAKRAAKKAAKPPEDLPSTVKKVGISAKKVTPTPLPKTKSVASPVKNLPKPETVAATGVATSAAKKSILTVLPKRLPDKDKEVVKRNVKDKVKTHGAADQEQISALIRDILDDEEPPTDDKFAEAAATVRQLDKQTSKNQGQQEAVPKQLGQEEEDNNDELEFLLEQDENSSDADVRHFKVERKVKRSASQSQSQNESQSEDDSLKVEPFNFVLIKESDNIGDLHEYLSTVVKTCFETLQFDWATVCCHCSLKCNKFETLLGHMQKCHQLDDERYICPIEGCKAELKGRKYLAMHLVVLHAPVAEIPIYGKCPECNMTFSNILQYNKHSCAHVIKKRRGMRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCDFADNNIDELFRHLYYAHEPEGTLFCDLCDRNFRDAAVFMEHNKSHANVSSTTYSCSECNANFETRGRLNGHMRSIHGSAISCELCSREFSTEATYSMHMKSHLIIERQVHVCSGCGLLSDSSAKLQAHMEAEDSACFGSETYAELLRNAYVCEYCSAYFKEKSDLRAHRDSGVHKNGLFICQPCDKPFSDMKLYRHHLRNFQQQRSDIAHRKLEICVFYMCDYEDCTEAYINWNSLYTHKRRSHDAITRHESLVKDNEWVCQFCQKQCRSKMSLSVHVARSHNNNNVICPLCKASYKDSDALSKHHAYWHEPMECSVCLKVVKNRRNYDTHMNVVHSNNKRYSCSFCQKGFYHKSEMEAHQRLHSQSYSCNQCSFVTRNRKSLSVHVMGQHYKRFAFECKACNKRFGRRQGLSNHMQRTHGSRYTCQDFFDGGCSKSFSSTTHLKLHVRKVHNGSIYLEDESVKAEDLDEQEEEQEEEEQQQLEQEEDEQKDGPSSSKKRCIRINGNTQIEFIGDATENKDKELLSELQEPKSNNKRQRQK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00551740;
- 90% Identity
- -
- 80% Identity
- -