Basic Information

Insect: Drosophila aldrichi
Gene Symbol: ken1
Assembly: GCA_035045965.1
Location: JAWNOM010000501.1:2272364-2274574[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0024 0.18 12.4 5.2 2 23 212 233 211 233 0.97

2 12 0.00044 0.033 14.7 0.3 1 23 239 264 239 264 0.93

3 12 0.0044 0.33 11.6 0.1 3 23 273 296 271 296 0.94

4 12 0.017 1.2 9.8 1.4 2 23 309 330 308 330 0.96

5 12 1e-05 0.00076 19.9 0.6 1 23 337 359 337 359 0.98

6 12 0.0061 0.45 11.1 0.1 1 23 365 387 365 387 0.98

7 12 0.012 0.87 10.2 4.0 1 23 393 416 393 416 0.97

8 12 0.0076 0.57 10.8 3.9 1 23 422 444 422 444 0.96

9 12 0.00093 0.069 13.7 2.9 2 23 451 472 450 472 0.96

10 12 8.8e-05 0.0065 16.9 1.6 1 23 570 593 570 593 0.95

11 12 0.012 0.86 10.2 0.7 1 19 599 617 599 621 0.95

12 12 1.8e-06 0.00014 22.2 0.4 1 23 627 649 627 649 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0024	0.18	12.4	5.2	2	23	212	233	211	233	0.97
2	12	0.00044	0.033	14.7	0.3	1	23	239	264	239	264	0.93
3	12	0.0044	0.33	11.6	0.1	3	23	273	296	271	296	0.94
4	12	0.017	1.2	9.8	1.4	2	23	309	330	308	330	0.96
5	12	1e-05	0.00076	19.9	0.6	1	23	337	359	337	359	0.98
6	12	0.0061	0.45	11.1	0.1	1	23	365	387	365	387	0.98
7	12	0.012	0.87	10.2	4.0	1	23	393	416	393	416	0.97
8	12	0.0076	0.57	10.8	3.9	1	23	422	444	422	444	0.96
9	12	0.00093	0.069	13.7	2.9	2	23	451	472	450	472	0.96
10	12	8.8e-05	0.0065	16.9	1.6	1	23	570	593	570	593	0.95
11	12	0.012	0.86	10.2	0.7	1	19	599	617	599	621	0.95
12	12	1.8e-06	0.00014	22.2	0.4	1	23	627	649	627	649	0.98

Sequence Information

Coding Sequence: ATGAGTACAAACACACCGTACTCTGTTCATTCAATATGCCGAGCTTGTCTAGAATATATCGATAGTACTGGGTATGACCTATTCTTATTGCCAGATCTTGCCAAGACTTACACAGTATGCACATCCTTGCTGTTGGATCCCCAAGATGGTTATCCAAGGAATCTCTGCTCCAGCTGTTATACTAGAGTAAACGACCTCCATGATTTTCAGAAGCTCTGTGTGTCCTCGTTGCAGCGCTTTAAGGAAATGGTAGCCAGCAAACTTATTGTGAAAGCGAATCCGATTGATATATTCGAGCCGCTGCCGGTAGGCAGCAACGAGGATGAACTCTTGGCTAAGGATGAGCAGACAAACAATGAATACGATCCGTTAAGTCACAAATTAGAGTTGATCGACAATGAAGAGgatgtatttaaaatgctCGAGAACGTCGACAAGGATGCCGACCTAAAACATAACTTAAGTGACTGTTCATCCGAGTGCAGCTTCAGCGAGGATGATGTACCTCTATCCCGCCGCCTGCTCGATCAGAACGTCGAAGTGGACAGTGAAACAACCAGTGAGAAATTGACCAATTGCAAAGCAAAACGAAGACGTATTCCTGCTAACGAACGACATCTTCGCCGCATCATCACCTGCCACATCTGCCAGCAGAAATTCAAGAAGCAAGTCAACTACGATGAGCATATGAAACACCACAACGAACTTTTGCCCTTTCAGTGCCATGTGGAGCAGTGCCAGAAGGGCTTTACTACAGCTGCCGCATTGCGTCTGCACGTGGACTACGCTCACACAAAGAGCGCCGCTGAGATCCCTTGCACTGTGGAGGACTGTAAGCTGGTGTTTCCGCGCATGCGACTGCTGACAATTCACCTAAAGAAGGTGCACAATATGGCGCGGACGAATGTGCCACGGGCGGAACAGCCGTGCAGGGAGTGTGGTGTGCAATTTCGCTGCCCCATGGCCCTTAAGAAGCATATGTATAAGCACACCGGCCAGCAGCTACCCTATCCCTGCAATATTTGCGGCAAGGGTTTCCACATCAACAGTGCTTTGAAGAATCATCTACTGCGACACGCCGGCATCAAGAACTATGTTTGTCCCTACTGTGGTGTGGGCAAAACAACTCGGCAGGAGTGGAGCAAACATAttctcacccacacacaagaAAAGATGTTCAAATGCCATATCTGCGATCATGCGACACACACAAAGCGGGCGTTGGACAACCATGTGAAGATTGTGCACGAGAAGATCAGGAACTATGCATGCCAGTATTGTGGAAAAACCTTTGGTAAATCGCATGCATGCAAAATCCACGAGATGACCCACACGGGCGAGAAGCGTTGCGAGTGCAAGGTGTGTGGCAAGAAATTTTTGTACACCGAGAGCTTGACGAAGCATCTGAAGATCCATGAGAAGAGTGTAGAACGTGCCATCGAAACGTATCGTCAACGTCAGGTGGAACTCAGCAGTCCCACAGCTGAACAGAGATGCATCGAATCTCAGGACAAAGCTGATGCCAATGCAGCTGATCAGCTATTAAAGGTCTGCGCCGAATCCGTAGCTACCATACCGCGAGATCCGAGGCGTGTCGAGCGCGTGGACATCTCGCAGTTGGCAGGCACTGTAGTGAATCCCATACCCGCTGTTCTAGTGCCCTCCAATACGCCAACACGCATTAACTTTGTGCAGAAGGAGGGCATGCACTTCTGTCCGGGCTGCAATCAGGGCTTCAACAATTTGGGCAATATGAAGCGGCATTATAAGAGCGTCCATGAGAAGGTGAAGGACTTTGAATGCCGCTTCTGCGCACGTCGTTTCGCCAACTCGCAGTCCCTCAAGCAGCACGAGTGGATACACACAGGCGAAAAGCCGTATGCTTGCCCGACCTGTGGCACCCATTTTCGGCAGGAGGCAGCTCTGATCCGCCATCAAAAGGTGCACGAACAGAAGCCACTGAAGCCGACAAAGCGTCCAAAGCAAATTACAGAAAAGTTTCGGCAAAAGGAGTTGCAGAGGTGCGAAAAGCGTCGCAAGGCTGAGGCGCTGCGTCAGAAGATCGCCGAGGCAGCCAAAGAAGAGCTGCAGGAGTTGGCCAAGCAGCGGGAGCTGGAGAAGCAACAAAATACCTACGAACAGTATAAAGCGGCggcagccgctgccgttgAAAAGACTCGCAACACAGACGAAATAGATCTGCCCAGCTGA
Protein Sequence: MSTNTPYSVHSICRACLEYIDSTGYDLFLLPDLAKTYTVCTSLLLDPQDGYPRNLCSSCYTRVNDLHDFQKLCVSSLQRFKEMVASKLIVKANPIDIFEPLPVGSNEDELLAKDEQTNNEYDPLSHKLELIDNEEDVFKMLENVDKDADLKHNLSDCSSECSFSEDDVPLSRRLLDQNVEVDSETTSEKLTNCKAKRRRIPANERHLRRIITCHICQQKFKKQVNYDEHMKHHNELLPFQCHVEQCQKGFTTAAALRLHVDYAHTKSAAEIPCTVEDCKLVFPRMRLLTIHLKKVHNMARTNVPRAEQPCRECGVQFRCPMALKKHMYKHTGQQLPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHILTHTQEKMFKCHICDHATHTKRALDNHVKIVHEKIRNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVERAIETYRQRQVELSSPTAEQRCIESQDKADANAADQLLKVCAESVATIPRDPRRVERVDISQLAGTVVNPIPAVLVPSNTPTRINFVQKEGMHFCPGCNQGFNNLGNMKRHYKSVHEKVKDFECRFCARRFANSQSLKQHEWIHTGEKPYACPTCGTHFRQEAALIRHQKVHEQKPLKPTKRPKQITEKFRQKELQRCEKRRKAEALRQKIAEAAKEELQELAKQRELEKQQNTYEQYKAAAAAAVEKTRNTDEIDLPS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00545421;
90% Identity: iTF_00544673;
80% Identity: -