Dald012776.1
Basic Information
- Insect
- Drosophila aldrichi
- Gene Symbol
- -
- Assembly
- GCA_035045965.1
- Location
- JAWNOM010000484.1:12103506-12106382[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 2.6 1.9e+02 2.9 0.2 2 23 114 136 113 136 0.90 2 13 0.0091 0.67 10.6 1.1 2 23 143 165 142 165 0.92 3 13 6.4e-07 4.8e-05 23.6 2.0 2 23 180 202 179 202 0.96 4 13 0.06 4.5 8.0 8.6 2 23 466 487 466 487 0.97 5 13 1.2e-06 8.5e-05 22.9 2.8 1 23 493 516 493 516 0.96 6 13 0.0055 0.41 11.3 0.3 1 23 521 544 521 544 0.96 7 13 6e-05 0.0044 17.5 5.5 1 23 562 584 562 584 0.96 8 13 0.00012 0.0089 16.5 1.6 1 23 589 611 589 611 0.98 9 13 3.1e-05 0.0023 18.3 1.7 1 23 617 639 617 639 0.95 10 13 0.00031 0.023 15.2 0.7 1 23 645 667 645 667 0.98 11 13 3.3e-07 2.4e-05 24.6 2.7 3 23 675 695 674 695 0.99 12 13 2.2e-08 1.6e-06 28.3 1.0 1 23 701 723 701 723 0.99 13 13 1.5 1.1e+02 3.6 5.2 1 19 728 746 728 751 0.88
Sequence Information
- Coding Sequence
- ATGCCTGACACCTACGGCCAATTCGATGCGGAGCGCGTCTGCCGTGTTTGCCTGCGCGAGGTGGGCGATTTCTACTTCATCTACGATGAGGCGCCCGTGGAGCAGGGCGCGAACATCGCCCAAATACTTAACGAGTGTACGCGTTACACCTGCGAGCGCTATGATAAGATGCCCCATCACATGTGCGACACCTGCATCAAGGCCGCCTGCCAAGCATACCGCTTCAAGCAGGACGCCGAGAAGGCCTACCGTTCGCTCGTGGCGATGCTGGGACGCACGCCTGTGACCAAGCCCAATAGCAGTGATGTCTGCACCCAGACTGATCAATTACCAATGCTGCCGTGTGGGATCTGTAGCGAAAAATTTCTAAACATTCTGGAATTGCGCCTACATCGCAGTCGCCAGCACATGAAAATTGAGGAGCTGAAGTGCAGGCTCTGCGGCGAGCAGTTCCAAAAGCTTCGTCAGCTGCGCAACCATCTCACCGAGCAGCATGATCAGAAGTCACCAGATTCGCCGTTGCTACGTCGGCGTCTGGAGTGTCGGGTTTGTCAACGTGAGTTCTCGCGACGCGATCATCTTATACGCCATATGCGAACAATCCACGATGTgcatcggcagcagcaactgaaggCTGCAGCGCCCTGGACGCCCAACGACGAGATAACTATGCAAAGCGGCGATGAGCTGGAATCAACCGCCGTCTTATTCAATGATCCGGCTGTCTGTTCGGATAACGAAAATAACGAGAGTGGCTATCAATGCCATACTACGAATCCTATATCAAGCAATGAGGATTCTGGCGATGATGAGGTGCATGCCGAGGCTAAAGAATCGCTCTGGCTGCACATCAAGCCAGAGCCAGAAGCAGAACTGGAAGCAGAGCAGGAGGCTGAGgcagaggcggaggcggaaATTGAGCAAGTGAAGCACGATAGgcgcaaaaagaaaacgaattcAAAGGTTGCAGTTCATACAGATACGGAGGAGGAGCCCGAAGGCGTCAGCAGGCTGAACCCAGCTTCGAGCTCATTTTCACCAGAGGTAAAAGAGGAGCCACTTGCCGCCGGTGGTGAGCAGCAGTTGTCCATTAAGCAAGAGCGACAGCGTGCTGACAGCATCAAGGTGGATGAGGACTATGAGATGGAGGCCGCAACAGCGGATCTATTTCACAGTGCCGAGGAGGAAGAAGACGCTGACGAGGAAAGCGACCTTGATGAAGTGGACGATGAAGctgaagaggaggaggaagcgAATGCCGAGCTCAATGAGGATAATCCAAAGCTGGCACAAGTGGAAATCGTACGAGAGTATTTACAAAAGCCCACAAAAGGCAAGCAGCGACGTAGACGGCGCAAGCAGACGCAAAGCGAAACCGAAGCAAATCCAGAGAATCGTTGCGATGTCTGCTTGCGCACCTTCTCCCGCCATTGCCATTTGCTGCGCCACAAGCTGTCCCATCTGGAGAAGAAGCCGCACAGCTGTCCGCATTGCCCCAAGGCTTTTGCGCGCAGCGATCATTTGAAGGCGCACGTCCAGAGCCTGCACGGCAATAAGGAGCACAAGTGCGTGCTCTGTGATGCGGCCTTCGCCCGTGTCGATGCCCTCGATCGGCACAAGATGAGCAAGCACAATGGCGAGGGTCTCGACGCCAGCAATGAGCTGAAGCTCCAAATGAGCGAGCACACGTGCGAGTACTGCTCGAAGCGTTTCTCCAGCAAGACCTACCTGCGCAAGCATACGCTGCTCCACACGGAGTTCCTGTACGCGTGCAAGAGCTGCGACGAGACGTTCAaggagcggcagcagctacGCAGCCACGAGAAGACCCACACCGGTCAGCGGAACTTCCTCTGCTGCATTTGCGGAGACAGTTTCGCGCGCAACGACTATCTGCGCGTCCATATGCGACGGCACAATGGCGAGAAGCCATACAAGTGCCGTTACTGCATCAAGGCATTTCCACGCGCCACAGACCTTAAGGTACACGAGCGGTACCACACTGGCACCAAGCCCAATCTGTGCAACACCTGCGGCAAGAGTTTCCATCGTGCCTACAATCTGACCATACATATGCGCACCCATACGGGCGAACGCCCGTACAAGTGTGACCAGTGCCCCAAGAGCTTCAGCCAGAGCAACGATCTGAAGGCTCACATACGACGGCATACGGGCGAGCGGTACAAGTGCCCCCATTGCGATGCCTACTTCCTGCAGCTCTATCACATGCGCAACCATTGCCTGAGTGCCCACAATAAGCACATTGAGACAAAGACGGGTCGGCTGCAGCGCACCGGCCTGCTGGACGAGCCCATTAACTCGCATCTGACCACGGTCGTTATGCCGCCTGCACGCTACCAGCAATCGACGCCCGATCCGCAACCAATGGCCTCTGTTACGACTCAGCTGCCCGCGGCAATTGCCACGTCCATAATGCATTCACCGGTGGCGTATAGTACAACGTCGCCAGTGCCGGTACCCGTAACCGTGTCCGTGCCACTGTCCGATGCAAGCGGATTCGTTGGTGCAACGACAAATGCAACGAGCACAACCGCGACGGCACCATTTGGCACCTTCAGTATAGCTCCTGTCGTGATGGCGCATCTGATGTACAATCATGGCGGGAACAGTCAACAAAGCAATGCGAGCAAATAG
- Protein Sequence
- MPDTYGQFDAERVCRVCLREVGDFYFIYDEAPVEQGANIAQILNECTRYTCERYDKMPHHMCDTCIKAACQAYRFKQDAEKAYRSLVAMLGRTPVTKPNSSDVCTQTDQLPMLPCGICSEKFLNILELRLHRSRQHMKIEELKCRLCGEQFQKLRQLRNHLTEQHDQKSPDSPLLRRRLECRVCQREFSRRDHLIRHMRTIHDVHRQQQLKAAAPWTPNDEITMQSGDELESTAVLFNDPAVCSDNENNESGYQCHTTNPISSNEDSGDDEVHAEAKESLWLHIKPEPEAELEAEQEAEAEAEAEIEQVKHDRRKKKTNSKVAVHTDTEEEPEGVSRLNPASSSFSPEVKEEPLAAGGEQQLSIKQERQRADSIKVDEDYEMEAATADLFHSAEEEEDADEESDLDEVDDEAEEEEEANAELNEDNPKLAQVEIVREYLQKPTKGKQRRRRRKQTQSETEANPENRCDVCLRTFSRHCHLLRHKLSHLEKKPHSCPHCPKAFARSDHLKAHVQSLHGNKEHKCVLCDAAFARVDALDRHKMSKHNGEGLDASNELKLQMSEHTCEYCSKRFSSKTYLRKHTLLHTEFLYACKSCDETFKERQQLRSHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCIKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFSQSNDLKAHIRRHTGERYKCPHCDAYFLQLYHMRNHCLSAHNKHIETKTGRLQRTGLLDEPINSHLTTVVMPPARYQQSTPDPQPMASVTTQLPAAIATSIMHSPVAYSTTSPVPVPVTVSVPLSDASGFVGATTNATSTTATAPFGTFSIAPVVMAHLMYNHGGNSQQSNASK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00532523;
- 90% Identity
- iTF_00554519;
- 80% Identity
- -