Basic Information

Insect: Drosophila affinis
Gene Symbol: -
Assembly: GCA_037356375.1
Location: CM074802.1:60433012-60437163[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0033 0.27 12.1 0.6 2 23 268 290 267 290 0.94

2 9 0.014 1.1 10.1 4.6 2 23 416 438 416 438 0.91

3 9 0.0064 0.53 11.2 2.3 2 23 511 533 510 533 0.94

4 9 0.062 5.1 8.1 3.7 1 19 640 658 640 663 0.94

5 9 0.00022 0.018 15.8 0.2 2 23 773 795 772 795 0.96

6 9 0.011 0.88 10.5 3.6 2 23 916 938 915 938 0.96

7 9 0.1 8.7 7.3 4.2 2 23 952 974 951 974 0.92

8 9 0.0082 0.68 10.8 0.4 2 23 1035 1057 1035 1057 0.95

9 9 0.033 2.7 8.9 0.7 1 23 1168 1190 1168 1190 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0033	0.27	12.1	0.6	2	23	268	290	267	290	0.94
2	9	0.014	1.1	10.1	4.6	2	23	416	438	416	438	0.91
3	9	0.0064	0.53	11.2	2.3	2	23	511	533	510	533	0.94
4	9	0.062	5.1	8.1	3.7	1	19	640	658	640	663	0.94
5	9	0.00022	0.018	15.8	0.2	2	23	773	795	772	795	0.96
6	9	0.011	0.88	10.5	3.6	2	23	916	938	915	938	0.96
7	9	0.1	8.7	7.3	4.2	2	23	952	974	951	974	0.92
8	9	0.0082	0.68	10.8	0.4	2	23	1035	1057	1035	1057	0.95
9	9	0.033	2.7	8.9	0.7	1	23	1168	1190	1168	1190	0.99

Sequence Information

Coding Sequence: ATGGCTGCATCCATATATGCCACCCCACCGCCAGATCTGAGCAGCGAGGACACTGCTCTCTCCGATGTCTCCAACTCGTCGACACTCAACACGAAccgaggcagcaacaacaatagcaacaacagcaacaataccaatgaagccacaagagcaacagcaaaagcaacagcagcagcagcagcaggaggaggaggagatggcACCATTTCACCCACGGAGCAGTTcaaggggcaggagcaggagcgggtGCAGGagtcgcagccacagccacagccgaaGCAGAAGCTAGCGGGAAGCAGCACAAATGAGGCAGACAATGCCGAAGACGATATGGAAACGGAAACTGGAGAgggaaatggagatggagtgGAGGATGGAGCGGGTCtggaagcagcagcggaaacggaaacggaagaGGGGGCCACCATGGCGGCCATGgcagcgacggcggcggcggcagccaaTGCGGCAGccatgcagctgcagctgctggaagCCCTCAGCGATGCGGCCAAGAAGCGACGCAAGCAGCACAATCCCATTCGCCTGGAGGCCCTCAACCTCAGTGGAGGCGACGGCGAGCCACCAGCAGAGATCGAGGATCGTAGGCAGGACACCGCCAGCCGGGTGGACTACGAGGAGAAGCTATCGAAGATGTTCCTGCCCAAGTCGATGGAGAAGCTGAAGGAGACCTTCGAGCTCctgcagcagcacaagcaggAGGAGCCCGAGCAGGATTCAGACCCTGCCAGCGAACACATATCAGAGGACAAGCATCAGCGAAGGAATCCGTATCAGACCTACTGCAAGCAGTGTGGCGAGAACTTCGAGACCGAGTTCAAGCTCAGTCTCCACATGCTGCAGGACCATCGCGAGGGTCAGAGTCACGACCAGGATCAAGATCGGGATGGGAACGAACCCATGGACTTTCTCAACTCAATCAAGGTGAAGCTGGAGCGGGAGGAGAGCCCCAATCAGCTGCAGGAACACATGCAGATGCAGCTGGACCATGACATGTCCAATGGCCATggcaaggagcaggagcacgaACAGGAACAGGATCACTGGTTCCGAGCCatggcccagcagcagcagcatcatccgCATGGCTCGGCGCTGGCGCCCGCCTTTCCCTTTCCACCTGGCATGGGTCCCGCGGGATATCTGCCGCTCCTCGGCATGTCGGGATTCCCCGGCGTGGACGGATTGAATCGTCCGCCGCTGCGCATCTTTAATCCGGAGGCCTACTGCGAGCTGTGCAACAAGGAGTTCTGCAACAAGTACTTCCTCAAGACGCACAAGGCCAACAAGCACGGGATCTTCGATCCTGTGGGAGAGCCCTCGTCCAATGcttccaacaacaacaacaataacaacaacaacaacaccacaagcagcaacaacaacagcaacagcggcagctcCATGAGCCACATGTTCCAGCTGCAGAGggaggcccaggcccagccaCCACCGAGCGTGGCCCCCAAAGCGGATCAGTCCGCAGCGGCCCCGCCGGCGGCCACGATCCACTGCGACATCTGCTCGAAGCGCTTTACCAACATCTTTGCCATGCGACGCCACCGAGCCAAGCAGCACGACCAGGCCGCTGACTCGTCGCCCAACTCCCAGCCCGGCCAGTCGCGGCGCGGCAGTCCCATTGAGTCATCGCCCCAGATCCAGTCCctgacacagcagcagcagggccagCCCATCAAGCAGGAGAGCCAGGCAGAGGTGGACATCCCCAAGCCCTTCCAGCTGCCCGAGGGATTCCGCGAGGACTTCTCCttggagcaggaggaggtgaACTTTGTGCCGCCGCCCCGCAAGCTGCCGTCGCACCTACAGCCGCAGGCCAGGGAGTCCAATCTCAGTGCGGAGAAGCTGCGACGTCTGGGCGTCCACTTCCCGGAGTTCTACTGCGAGCTGTGCCACAAGGAGTACGCAAACAGGTACTTCCTGCGCACCCACAAGTGGAAGCGGCATGGGGTGTTCGTGCCGCCGGAGGACTTGCCGCAGATTGGCAAGGATGAGGCACAGCTGAGCGGCTGGCCCTTTATGCCCCTGAATCTGATGCTGGCCAAGGCAGCGGCGGCCGCTTCGATGGAGCAGGCCGAGGCCGAACAGGAGCCCGAGCAGGAGCCAGAGCCCGAGCAGGAGCAAGATCTGATCGAGCAGCCCAGCAAGCGGATCAAGCTGGAGCCGGACCTGGACGAAGAGAAGCTCAACGGGTCCGTCATGGGGCTGCAGAACCTCCAGAAGCTGCAGTCaatgctgcagcagctcaaCGACATCAACGGGAAGCGACCCCTACCCTGCCACCTGTGCGGCCGGGAGCTGGAGAACCAGTACGCCCTGCGAGCACATCTCATGACGGAGCATGCCGCCCAGATGCAGATGCCCTTGCAGATGCCCCTTCAGATGGCACCCATGTCCATGCCACTGCCCGAGCAGCATCCGCAACAGCTGCCCCTGCACGCCCTCTACCAACAGCAGGCAGCCCCACAAACGCCCCCGAATGGAGGGGCTGGAGGAGCCAGATCCTCGCCAGGAAGTGGCGAGGAGTTCAAGCAACATATCGCCGAATCGCACTTGCCCAGGGGAGCGACCGCTCCGAGTGGGAGTCCACTGCGCGAGGGCTTCTACACGCCCGAGCGTCCGGTGGCACCACCAGCAGGCACTGGCAGTGTCCCCGTGCCGCCACCAAATCGGCCGGCCTACACGATAACCCCGACGAGCAGCTACTGCGAGATCTGCAACAAGGAGCTCTGCAACAAGTACTTCATGAAGACCCACATGCAGCGGATGCACGGCATCGAGATCGAGAACGGGGCCCAGATCGGGGGCGTGGTGTGCAATATCTGCAACAAGGAGCTGTGCAGCAAGTACTTCCTGCGCGTCCACAAGCACAACACCCACGGCATCATCGAGGAGGGCTCGCCCCTCCCGCAGCCGCGAGGCCAGAACGGCGTCAAGCTCGAGGCGGcggccgcagccgcagcgcaACAGGCGCCGCCCATACAGCCAGAGCAGCAGGAACTCAATCTGACTCCTTCCGCAGCACCAGGGGGAGAGACCAGCTCCGGCAGTGGCCACGAGGTGTGTCCGCTGTGTGCGCGACAGTTCCGTAGCTTCAAGTGGCTCCGCTCGCATCTGATGAACGAGCACGGACCGGCCGGAGTGGAGCGACTCAGGGAGCTGGAGGCTACACAGACAGCCCCGGCTTCGGCTCCATCTGCACGCAGCAAGCCCAACAGTCCCACGCTCAAGATACCCAAtgggagcaacagcagcagcaatgctCCGTCTGCAACGCCATCCGTGGGAGCTGGCAATCCGCCACCCAATCTCGCCCAGGCCCTGCAGAACCTTAATGCGCAGCATTTGTTCGgacagatgcagcagcagcagcagcaggggcccAAGGCCATGCAGGGGATGCCGCCAATGCCACCTCTGCCCGGGATGTTCGGTGAGCAGGCGCCACGCTTCAAGGAGTACCAGTGCTCCATGTGCCCCTTCACCACGCCCTACTACGCGTTCCTCTTCATCCACGAGCGCTCGCACGCCCTGCTCAACAGTGCCGATGGGGTGGAGGCGTCTTTGGAGGCGCCACCGCCTCCCCCAGCCGCCCGTAGTCAGGGCAAGTCCCGCAGCAAAGCCAGTCGAGTGGCAGCAGCTCCGCCAGCTGTGGAGGAAGCCGATCTTCACGTGGAACCCACCAACCTAAGCACCTCCAAGGCCACAACCCTCCAGAGAACCCACTCTCCTCCACAACACACACCCGGAACTCCCTCACCAAAGGCCACGGGCCGCGCCCAGTCGCCGCTGGCCGCATCCAAGAACCGCTCACCGAATCCAGGACGTCGCTCCTCCAAGTCGATCACACCCAATGGGATCGGAGGGGGCCACAGGTCAGCCGCCACCTCGCCCTTTGAGGTGTGCTCCGATCTGGCCAACGGCACCGGAAAGCCGGCTAGCTACGCTCAGCCGGATCGGGCCGAAGAAGCATATCAGATGCAGGCCTTCCATCTGCAGCCAGCCGATCCGGACTCGGAGATGCAGTTTGCCCCGGCTCTGGTCTATCTGCCCGTGAGGGTGCGGGCCTCGGAGTCGGCCACGCTGAGCTTCAGACTAACACCAGCCTAA
Protein Sequence: MAASIYATPPPDLSSEDTALSDVSNSSTLNTNRGSNNNSNNSNNTNEATRATAKATAAAAAGGGGDGTISPTEQFKGQEQERVQESQPQPQPKQKLAGSSTNEADNAEDDMETETGEGNGDGVEDGAGLEAAAETETEEGATMAAMAATAAAAANAAAMQLQLLEALSDAAKKRRKQHNPIRLEALNLSGGDGEPPAEIEDRRQDTASRVDYEEKLSKMFLPKSMEKLKETFELLQQHKQEEPEQDSDPASEHISEDKHQRRNPYQTYCKQCGENFETEFKLSLHMLQDHREGQSHDQDQDRDGNEPMDFLNSIKVKLEREESPNQLQEHMQMQLDHDMSNGHGKEQEHEQEQDHWFRAMAQQQQHHPHGSALAPAFPFPPGMGPAGYLPLLGMSGFPGVDGLNRPPLRIFNPEAYCELCNKEFCNKYFLKTHKANKHGIFDPVGEPSSNASNNNNNNNNNNTTSSNNNSNSGSSMSHMFQLQREAQAQPPPSVAPKADQSAAAPPAATIHCDICSKRFTNIFAMRRHRAKQHDQAADSSPNSQPGQSRRGSPIESSPQIQSLTQQQQGQPIKQESQAEVDIPKPFQLPEGFREDFSLEQEEVNFVPPPRKLPSHLQPQARESNLSAEKLRRLGVHFPEFYCELCHKEYANRYFLRTHKWKRHGVFVPPEDLPQIGKDEAQLSGWPFMPLNLMLAKAAAAASMEQAEAEQEPEQEPEPEQEQDLIEQPSKRIKLEPDLDEEKLNGSVMGLQNLQKLQSMLQQLNDINGKRPLPCHLCGRELENQYALRAHLMTEHAAQMQMPLQMPLQMAPMSMPLPEQHPQQLPLHALYQQQAAPQTPPNGGAGGARSSPGSGEEFKQHIAESHLPRGATAPSGSPLREGFYTPERPVAPPAGTGSVPVPPPNRPAYTITPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVVCNICNKELCSKYFLRVHKHNTHGIIEEGSPLPQPRGQNGVKLEAAAAAAAQQAPPIQPEQQELNLTPSAAPGGETSSGSGHEVCPLCARQFRSFKWLRSHLMNEHGPAGVERLRELEATQTAPASAPSARSKPNSPTLKIPNGSNSSSNAPSATPSVGAGNPPPNLAQALQNLNAQHLFGQMQQQQQQGPKAMQGMPPMPPLPGMFGEQAPRFKEYQCSMCPFTTPYYAFLFIHERSHALLNSADGVEASLEAPPPPPAARSQGKSRSKASRVAAAPPAVEEADLHVEPTNLSTSKATTLQRTHSPPQHTPGTPSPKATGRAQSPLAASKNRSPNPGRRSSKSITPNGIGGGHRSAATSPFEVCSDLANGTGKPASYAQPDRAEEAYQMQAFHLQPADPDSEMQFAPALVYLPVRVRASESATLSFRLTPA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00484711;
90% Identity: iTF_00581083;
80% Identity: -