Basic Information

Insect: Drosophila affinis
Gene Symbol: su(Hw)
Assembly: GCA_037356375.1
Location: JAZHFB010000003.1:27259304-27262279[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00065 0.054 14.3 2.2 1 20 213 232 213 234 0.94

2 12 2.7e-06 0.00022 21.8 0.4 3 23 285 306 283 306 0.93

3 12 0.039 3.3 8.7 0.0 1 23 312 334 312 334 0.95

4 12 5.3e-07 4.4e-05 24.0 2.4 1 21 341 361 341 362 0.95

5 12 6e-06 0.0005 20.7 1.0 2 23 374 395 373 395 0.96

6 12 0.00027 0.023 15.5 6.3 1 23 406 428 406 428 0.99

7 12 7.9e-05 0.0065 17.2 0.9 1 23 434 456 434 456 0.97

8 12 9.1e-06 0.00076 20.1 0.7 1 23 462 484 462 484 0.98

9 12 1.4e-06 0.00012 22.6 3.0 1 23 490 512 490 512 0.98

10 12 1.6e-05 0.0013 19.3 0.5 1 23 516 538 516 538 0.97

11 12 2e-05 0.0017 19.0 0.1 1 21 546 566 546 570 0.92

12 12 2.6e-05 0.0022 18.7 0.4 3 23 590 611 588 611 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00065	0.054	14.3	2.2	1	20	213	232	213	234	0.94
2	12	2.7e-06	0.00022	21.8	0.4	3	23	285	306	283	306	0.93
3	12	0.039	3.3	8.7	0.0	1	23	312	334	312	334	0.95
4	12	5.3e-07	4.4e-05	24.0	2.4	1	21	341	361	341	362	0.95
5	12	6e-06	0.0005	20.7	1.0	2	23	374	395	373	395	0.96
6	12	0.00027	0.023	15.5	6.3	1	23	406	428	406	428	0.99
7	12	7.9e-05	0.0065	17.2	0.9	1	23	434	456	434	456	0.97
8	12	9.1e-06	0.00076	20.1	0.7	1	23	462	484	462	484	0.98
9	12	1.4e-06	0.00012	22.6	3.0	1	23	490	512	490	512	0.98
10	12	1.6e-05	0.0013	19.3	0.5	1	23	516	538	516	538	0.97
11	12	2e-05	0.0017	19.0	0.1	1	21	546	566	546	570	0.92
12	12	2.6e-05	0.0022	18.7	0.4	3	23	590	611	588	611	0.96

Sequence Information

Coding Sequence: ATGAGCGCCGCAAAGGAGGGAAGAAAGACAGATGGCTCCTCCGAAAGGAGCAGCCGGGCCAACACGACTGTAGTGAAAATAATTGGCGTGGACAAACTATGCTTGCCCAAAGTCAAGGGACCAACGACGCGCATGAAGTTGCTCAACGACGTCGCCGCCTCTGCCAAGCCGGAGAAACGTGGTAGCCTTGGTGGCGCTCGTATTAAAATTCTCAACGAGGAGGTCTTGAGCACCCCGAAAGCCGACAAACGCAGCCCACAAAAGACAGTCAGCCCCTCGGGATCTGTCAAGATATTAAACGAGAAGCGAATGGCACCATCCACGGCGACAGCTGTGGAGACGACAAAGATCAAGACGTCCCCCACcaaacagaagaagaaaatgGATCATTATGTGCTGCAGGCCGTAAAGGCGGAGAACAGCAAAGCAGACACCACATCGAGTGTATCCGAGGAGGACGAAAGCATTGCCTTCATCCTGGCCGACGACGATGAGATGGAACCTGTGGCGGGTCGAGCCAATGGCGAGGAGATTGTGGTTTCCAGTGCAGATGAGGACAATGAGGACGACGAAGAGGGCGATAATTCGGTGGAACGGGCCAGTAGCAGCCAAGGGGCGATCAAGGAGATGGTCGAACACGTTTGCGGCAAGTGCTACAAGACGTTCCGTCGCGTGAAGAGCCTGAAGAAGCACTTGGAATTCTGTCGCTACGACAGTGGCTATCACCTGCGCAAGGCGGAGATGCTTAAAAACTTGGAGAAGATTGAAAAGGATGCTGTGGTGATGGAGAAAAAGGACAtttgcttctgctgcagcGAGAGCTACGACACCTTTCATTTGGGCCACATCAATTGCCCCGATTGCCCAAAGTCATTCAAGACGCAGACCAGCTATGAGCGTCACATCTTCATCACGCACTCGGAGTTCAACACCTATCCCTGCTCCATTTGCAATGCCAATTTGCGCAGCGCCGCCCTGCTGACGCTTCACGAGGAGCAACACAAGTCTCGTGGCAAACCGTATGCCTGTAAGATATGTGGCAAGGACTTTACCCGCTCATATCACCTGAAGCGCCACCAGAAGTACTCGTCCTGCTCGGCCAATGAGAACGATACCATGAGCTGCAAGGTGTGCGATCGTGTCTTCTATCGCCTGGACAATCTGCGCTCGCATCTGAAGCAACATTTGGGCACACAAGTGGTGAAGAAACCAGAGTACATGTGCCACACCTGCAAGAACTGCTTCTACAGCTTGTCCACGCTGAACATACACATACGCACCCACACTGGGGAGAAGCCCTTCGATTGCGATCTCTGTGACAAGAAGTTCTCGGCCTTGGTGGCTCTCAAGAAGCATCGACGCTACCACACAGGCGAGAAACCCTACAGCTGCACAGTGTGCAATCAATCCTTTGCCGTCAAGGAGGTGCTCAATCGCCACATGAAGCGACACACTGGAGAGCGTCCGCACAAGTGCAACGAGTGTGGCAAGAGCTTCATCCAGGCCACCCAGCTGCGCACCCATTCCAAAACCCATATACGTCCATATGCCTGCGATTTGTGCGATGAAAAGTTCAAGACAGAGAAGCAACTCGAGCGTCACGTCAAGGAGCACACACGACAGAAGCGTGCCTCTTTCGCTTGCACTGAATGCAAGCGTACCTTCCGGACCCCGGCCTTGCTCAAGGAGCACATGGATGCCGGCGATCATTCGCCCAAACCGCAACGCGCCAAGCGCACTGCAACCAAGGTTATCGAGCGCACAGACTGCGCCATTTGTGACAAGAACTTCGACAGCACCGAGACCTTGCGCAAGCACATCCGCTCCGTTCACGAATGCGATCCGGATGACATCTTTGGTGTCGAACCGCCAGCAGCAAAGCGCAGCAAGAAGTCCAAAAAGTCAGCCGACGCAGACGAGGATACAGAAACCGTGGAGCTTGATACTTCGGCGGGATCGCTCATTTCCAGCCAAACAGATGGCAATGGGGTTGTGGTCAGGGAGTTTCTGGTGGACGATGGCAATGCGCAGACCATCTTGCTAGAGAACGAAACGTACACCATTCTGCCCCTGGATGGGGCCATCAGCAGCGACCAACAGGCGGCCGGAAAAGGGGATACTGTTAAGCCGGAGGCCAACAAAAGTGAGTCCAAGAAAGCAGTGGTTTCGCCGGTGGTCAAGAAGGAGCAGCGAAAATCACTGGGGGCCAGCTTGGCAGCAGCCATTGCAGACAACATGGAGGATCCGGCAAGTGACGATGACGATTTCAGCGGCGATGTACTCACCGAAGCCGACCTGAAGCTCAAGGAGAATGTGGCCAAGTTGATTGACATGCTGGTCGATCCGCACGTCCTCAAGAAGTACGGCTGGCCCAACACCTCCGAGGAGACAATGCTCTGCAAGGTGATCGAGAACTGTGGCCACGATCTGAGCAAGGATGAAGAGAACTACGCTGAGTTGGAATACGGCGATCGTATGCGCGAATATTGCAAGCTTCTCTTCACTGTGGTCATCCACAACGAATCCATACGGTCCCTGCTCAACAACTTCCCCATCGACGATGTCATCGAGTATGTCCTGGGCGACGAGGACCAGgacgaggaggatgaggatggcAAGCAAAAAGACAGTGATGCTGCGTCCGACCACAAGTCGGAAACCGCAGAGACCCCCGAAGCTAAGGCTTAG
Protein Sequence: MSAAKEGRKTDGSSERSSRANTTVVKIIGVDKLCLPKVKGPTTRMKLLNDVAASAKPEKRGSLGGARIKILNEEVLSTPKADKRSPQKTVSPSGSVKILNEKRMAPSTATAVETTKIKTSPTKQKKKMDHYVLQAVKAENSKADTTSSVSEEDESIAFILADDDEMEPVAGRANGEEIVVSSADEDNEDDEEGDNSVERASSSQGAIKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKAEMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNTYPCSICNANLRSAALLTLHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVVKKPEYMCHTCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHIRPYACDLCDEKFKTEKQLERHVKEHTRQKRASFACTECKRTFRTPALLKEHMDAGDHSPKPQRAKRTATKVIERTDCAICDKNFDSTETLRKHIRSVHECDPDDIFGVEPPAAKRSKKSKKSADADEDTETVELDTSAGSLISSQTDGNGVVVREFLVDDGNAQTILLENETYTILPLDGAISSDQQAAGKGDTVKPEANKSESKKAVVSPVVKKEQRKSLGASLAAAIADNMEDPASDDDDFSGDVLTEADLKLKENVAKLIDMLVDPHVLKKYGWPNTSEETMLCKVIENCGHDLSKDEENYAELEYGDRMREYCKLLFTVVIHNESIRSLLNNFPIDDVIEYVLGDEDQDEEDEDGKQKDSDAASDHKSETAETPEAKA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00487439;
90% Identity: iTF_00473938;
80% Identity: -